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Quantitative analysis and pharmacokinetic study of a novel diarylurea EGFR inhibitor (ZCJ14) in rat plasma using a validated LC-MS/MS method
Published 2021-09-01“…Chromatographic separation of ZCJ14 and internal standard (IS) [1-phenyl-3-(4-((3-(trifluoromethyl)phenyl)amino) quinazolin-6-yl)urea] was accomplished by gradient elution using the Kromasil C18 column. The selected reaction monitoring transitions were performed at m/z 507.24→436.18 and 424.13→330.96 for ZCJ14 and IS, resp. …”
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Purification and Characterization of Hemagglutinating Proteins from Poker-Chip Venus (Meretrix lusoria) and Corbicula Clam (Corbicula fluminea)
Published 2012-01-01“…Hemagglutinating proteins (HAPs) were purified from Poker-chip Venus (Meretrix lusoria) and Corbicula clam (Corbicula fluminea) using gel-filtration chromatography on a Sephacryl S-300 column. The molecular weights of the HAPs obtained from Poker-chip Venus and Corbicula clam were 358 kDa and 380 kDa, respectively. …”
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PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway
Published 2014-01-01“…Phorbol 12-myristate 13-acetate (PMA) was isolated as an active component of Croton tiglium by activity-guided fractionation, column chromatography, HPLC, NMR, and MS. PMA at a range of nM induced PKC-dependent NF-κB activation and IL-8 production in both TLR5− and TLR5+ assay systems. …”
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Efficient diagnosis of diabetes mellitus using an improved ensemble method
Published 2025-01-01“…Data preprocessing included cleaning the dataset by replacing missing values with column means and selecting highly correlated features using forward and backward selection methods. …”
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WEAR AND CRACK initiation PREDICTION OF RAIL IRREGULARITY WELDING ZONE
Published 2024-01-01Get full text
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A reliable analytical procedure to determine the carbon isotopic signature of CO<sub>2</sub>-bearing COH fluids generated in petrological experiments
Published 2025-01-01“…The optimal values of the carrier gas flow in the QMS, sampling times, and chromatography column temperature for IRMS are determined. The high degree of similarity, within acceptable errors, observed in both compositional and isotopic analyses indicates a robust reproducibility, minimally affected by contamination and fractionation effects during sampling. …”
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Global seasonal urban, industrial, and background NO<sub>2</sub> estimated from TROPOMI satellite observations
Published 2025-01-01“…<p>The tropospheric NO<span class="inline-formula"><sub>2</sub></span> vertical column density (VCD) values measured by the Tropospheric Monitoring Instrument (TROPOMI) were used to study the NO<span class="inline-formula"><sub>2</sub></span> variability and estimate urban NO<span class="inline-formula"><sub><i>x</i></sub></span> emissions for 261 major cities worldwide. …”
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