“A quien perturbe el orden público le caerá el rigor de las penas, hasta la de muerte”. Aproximaciones al tratamiento de la pena capital en el Río de la Plata en la década de 1820.... by María Cecilia Guerra Orozco

“…El clero fue uno de los actores fundamentales dentro del entramado social colonial. Este rol principal sufrió algunas modificaciones a partir de mayo de 1810, cuando la revolución empezó a delinear una nueva forma de relación entre la Iglesia y los individuos que la componían, y los nuevos poderes emergentes. …”
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Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia by Yu Zhang, Zhao Yin, Zurong Yao, Dan Xu, Xuejie Jiang, Xiaqi Nie, Dandan Chen, Hongsheng Zhou, Pengcheng Shi, Hui Liu, Qifa Liu, Guopan Yu

“…Background: We aim to analyze the efficacy and safety of Venetoclax (Ven) added to cladribine + cytarabine + granulocyte colony-stimulating factor (G-CSF) ± idarubicin or mitoxantrone (CLAG ± Ida/Mito) regimen as a salvage treatment of relapsed/refractory acute myeloid leukemia (RR-AML). …”
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RELIGIOUS KNOWLEDGE IN CONTEMPORARY INDONESIA: The Contributions of Al Washliyah Madrasahs and Scholars to the Development of Hadith Studies by Ja'far Ja'far, Umar Muhammad Noor

“…The findings indicate that hadith has been introduced and taught across all Al Washliyah educational institutions from the Dutch colonial period to the present. Several Al Washliyah scholars have published works on hadith studies in both Arabic and Indonesian. …”
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Refractory myasthenia gravis treated with autologous hematopoietic stem cell transplantation by Benjamin Beland, Jan Storek, Liam Quartermain, Christopher Hahn, C. Elizabeth Pringle, Pierre R. Bourque, Michael Kennah, Natasha Kekre, Christopher Bredeson, David Allan, Kareem Jamani, Christopher White, Harold Atkins

“…Stem cells were mobilized with cyclophosphamide and granulocyte colony‐stimulating factor. The grafts were depleted of immune cells by selecting CD34+ cells. …”
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RapidBenthos: Automated segmentation and multi‐view classification of coral reef communities from photogrammetric reconstruction by Tiny Remmers, Nader Boutros, Mathew Wyatt, Sophie Gordon, Maren Toor, Chris Roelfsema, Katharina Fabricius, Alana Grech, Marine Lechene, Renata Ferrari

“…Additional validation of 524 Acropora coral colonies from 11 additional test plots resulted in a segmentation accuracy of 0.92 and classification accuracy of 0.88 to the coarser ‘Acropora’ group. …”
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Soft computing approaches of direct torque control for DFIM Motor's by Zakariae Sakhri, El-Houssine Bekkour, Badre Bossoufi, Nicu Bizon, Mishari Metab Almalki, Thamer A.H. Alghamdi, Mohammed Alenezi

“…This article provides a critical analysis of the following cutting-edge methods: DTC with Space Vector Modulation (DTC-SVM), DTC based on Fuzzy Logic (DTC-FL), DTC using Artificial Neural Networks (DTC-ANN), DTC optimized by Genetic Algorithms (DTC-GA), DTC with Ant Colony Optimization (DTC-ACO), DTC with rooted tree optimization (DTC-RTO), Sliding Mode Control (DTC-SMC), and Predictive DTC (P-DTC). …”
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Impact of the unconventional extraction on antioxidants and antimicrobial characteristics of hibiscus and olive leaves extracts by Abdel-Aziz R.E. El-Hadary, Ayat M.A. Abulmakarm, A.M. Sulieman, Gehan A. El-Shorbagy, Alaa S. Mohamed

“…The absolute ethanolic extracts registered high efficiency (P < 0.05) and the olive leave extract was the highest (273.5 ± 1.5 mg GAE g−1 of dried extract, 18.1 ± 0.8 μg mL−1 to IC50, 86.2 ± 0.2 % to βCB, 91.16 ± 0.45 % to TBARs, 34.94 ± 0.7 (P < 0.05) to inhibitor the growth of Staphylococcus aureus, and 1.25 ± 0.5 (P < 0.05) to diameter the colony of Aspergillus ochraceus). The results also showed that DPE extraction not only reduced the extraction time to 12.5 % (P < 0.05) (from 48 h to only 6 h), but also registered higher efficiency in antioxidant and antimicrobial activity compared with the conventional extraction method.…”
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Cloning, expression, and purification of fusion antigens MPT83 and ESAT6 from the local strain of Mycobacterium tuberculosis in Escherichia coli as a seed vaccine candidate against... by Rusdina Bte Ladju, Ahyar Ahmad, Abdul Karim, Rugaiyah Arfah, Rosana Agus, Najdah Hidayah, Muhammad Nasrum Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani

“…The existence of the appropriate recombinant Rv2873 + Rv3875 fusion genes was confirmed through the observation of a band of 948 base pairs in the colony PCR product containing fusion antigens. A band measuring 3966 base pairs was observed in the recombinant plasmid pGEM-T Easy- Rv2873+Rv3875, supporting the presence of the desired fusion genes target. …”
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CTX-M, SHV, TEM and VEB β-lactamases, and MCR-1 among multidrug-resistant Escherichia coli and Klebsiella isolates from environment near animal farms in Thailand by Arpasiri Srisrattakarn, Bhanubong Saiboonjan, Patcharaporn Tippayawat, Sunpetch Angkititrakul, Aroonwadee Chanawong, Chanakan Pornchoo, Chokdee Smithkittipol, Aroonlug Lulitanond

“…The samples were cultured in appropriate media and isolated colonies were further identified. Antimicrobial susceptibility and ESBL production were tested by disk diffusion method except for colistin susceptibility determined by broth disk elution test. …”
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A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats by Pleydell, David R.J., Ndong Bass, Innocent, Mba Djondzo, Flaubert Auguste, Meta Djomsi, Dowbiss, Kouanfack, Charles, Peeters, Martine, Cappelle, Julien

“…The current study presents an age-structured epidemiological model that characterises the effects of seasonal birth pulses on ebolavirus transmission within a colony of African straw-coloured fruit bats (Eidolon helvum). …”
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Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…In vitro, SLC3A2's influence on cell proliferation, migration, and invasion was evaluated through CCK8, wound healing, colony formation, transwell assays, and cell cycle analysis.ResultsIn this study, we identified the high expression of SLC3A2 in NPC and head and neck squamous cell carcinoma (HNSC) and analyzed its potential mechanism and correlation with patient prognosis. …”
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Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia by Chandra Prakash Chaturvedi, Naresh Kumar Tripathy, Ekta Minocha, Akhilesh Sharma, Khaliqur Rahman, Soniya Nityanand

“…., macrophage inflammatory protein (MIP)-1α, tumor necrosis factor (TNF)-α, granulocyte colony-stimulating factor (G-CSF), stromal cell-derived factor (SDF)-1α, stem cell factor (SCF), and transforming growth factor (TGF)-β in lipopolysaccharide-induced bone marrow mesenchymal stem cells (BM-MSCs) and levels of their soluble forms in the culture supernatants of BM-MSCs and BM plasma of patients with acquired aplastic anemia (AA) (n=29) and controls (n=29). …”
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Characterization of subcutaneous and visceral de-differentiated fat cells by Yan Li, Houyu Zhang, Carlos F. Ibáñez, Meng Xie

“…We also show that high-fat diet (HFD) feeding enhances DFAT cell colony formation and re-differentiation into adipocytes, while switching from HFD to chow diet (CD) only reverses their re-differentiation. …”
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Pentavalent Antimonials Combined with Other Therapeutic Alternatives for the Treatment of Cutaneous and Mucocutaneous Leishmaniasis: A Systematic Review by Taisa Rocha Navasconi Berbert, Tatiane França Perles de Mello, Priscila Wolf Nassif, Camila Alves Mota, Aline Verzignassi Silveira, Giovana Chiqueto Duarte, Izabel Galhardo Demarchi, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Jorge Juarez Vieira Teixeira, Thaís Gomes Verziganassi Silveira

“…Sixteen articles were selected and the pentavalent antimonials were administered in combination with pentoxifylline, granulocyte macrophage colony-stimulating factor, imiquimod, intralesional sodium stibogluconate, ketoconazole, silver-containing polyester dressing, lyophilized LEISH-F1 protein, cryotherapy, topical honey, and omeprazole. …”
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An AI-Based Digital Scanner for <i>Varroa destructor</i> Detection in Beekeeping by Daniela Scutaru, Simone Bergonzoli, Corrado Costa, Simona Violino, Cecilia Costa, Sergio Albertazzi, Vittorio Capano, Marko M. Kostić, Antonio Scarfone

“…A major threat is the <i>Varroa destructor</i> mite, which feeds on honey bee fat bodies and transmits viruses, leading to significant colony losses. Detecting the parasite and defining the intervention thresholds for effective treatment is a difficult and time-consuming task; different detection methods exist, but they are mainly based on human eye observations, resulting in low accuracy. …”
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Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects by Agnieszka Żak-Gołąb, Piotr Kocełak, Małgorzata Aptekorz, Maria Zientara, Łukasz Juszczyk, Gayane Martirosian, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…Positive correlations between bacterial colony count and sTNFR1 (r=0.33, P<0.01) and plasma zonulin (r=0.26, P<0.05) but not haptoglobin levels were found. …”
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Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

“…Both CCG-257081 enantiomers robustly suppressed development of Vem-resistant colonies with the S isomer being more potent (1 μM IC50).ConclusionCCG-257081 appears to target pre-resistant cells and Vem-induced resistant cells through enhanced apoptosis. …”
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Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC by Domenico Lo Tartaro, Beatrice Aramini, Valentina Masciale, Nikolaos Paschalidis, Francesco Demetrio Lofaro, Anita Neroni, Rebecca Borella, Elena Santacroce, Alin Liviu Ciobanu, Anna Valeria Samarelli, Federica Boraldi, Daniela Quaglino, Alessandra Dubini, Michele Gaudio, Gloria Manzotti, Francesca Reggiani, Federica Torricelli, Alessia Ciarrocchi, Antonino Neri, Federica Bertolini, Massimo Dominici, Pier Luigi Filosso, Franco Stella, Lara Gibellini, Sara De Biasi, Andrea Cossarizza

“…VISTA+ Bregs displayed high metabolic demand and were able to produce different cytokines, including interleukin (IL)-10, transforming growth factor (TGF)-β, IL-6, tumor necrosis factor (TNF), and granulocyte–macrophage colony-stimulating factor (GM-CSF). Spatial analysis showed colocalization of B cells with CD4+/CD8+ T lymphocytes in TME. …”
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Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis by Juliana Carvalho de Quaglia e Silva, Amanda Manoel Della Coletta, Taiane Priscila Gardizani, Graziela Gorete Romagnoli, Ramon Kaneno, Luciane Alarcão Dias-Melicio

“…Therefore, analysis of Dectin-1 receptor expression was done by flow cytometry whereas the effector mechanisms were evaluated by fungal recovery by colony-forming unit (CFU) counting and hydrogen peroxide (H2O2) production. …”
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Skeletal Site-Specific Lipid Profile and Hematopoietic Progenitors of Bone Marrow Adipose Tissue in Patients Undergoing Primary Hip Arthroplasty by Drenka Trivanović, Marko Vujačić, Aleksandra Arsić, Tamara Kukolj, Milica Rajković, Nikola Bogosavljević, Zoran Baščarević, Mirjana Maljković Ružičić, Jovana Kovačević, Aleksandra Jauković

“…This was associated with a higher incidence of total clonogenic hematopoietic progenitors and late erythroid colonies CFU-E in femoral BMAT when compared to acetabular BMAT, similar to their BM counterparts. …”
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