Metallothioneins in Inflammatory Bowel Diseases: Importance in Pathogenesis and Potential Therapy Target by Anna Socha-Banasiak, Patrycja Sputa-Grzegrzółka, Jędrzej Grzegrzółka, Krzysztof Pacześ, Piotr Dzięgiel, Beata Sordyl, Hanna Romanowicz, Elżbieta Czkwianianc

“…In the treatment of patients with Crohn’s disease (CD) and ulcerative colitis (UC), it is increasingly common to use biological drugs that selectively affect individual components of the inflammatory cascade. …”
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Image Characterization of Cancer of the Colon by Thaimi Conde Cueto, Martha Yudey Rodríguez Pino, Pedro Juan Barrios Fuentes, Bárbara Aleida García Hernández, Julio Suz Piña, Nery M. Díaz Yanes

“…It was mainly associated to idiopathic ulcerative colitis and to family history of cancer of the colon and cholecystectomy. …”
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Five-Aminosalicylic Acid: An Update for the Reappraisal of an Old Drug by Cristiana Perrotta, Paolo Pellegrino, Eliana Moroni, Clara De Palma, Davide Cervia, Piergiorgio Danelli, Emilio Clementi

“…Inflammatory bowel disease (IBD) comprises several conditions with chronic or recurring immune response and inflammation of the gastrointestinal apparatus, of which ulcerative colitis and Crohn’s disease are the commonest forms. …”
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Toxicity Associated with Pembrolizumab Monotherapy in Patients with Gastrointestinal Cancers: A Systematic Review of Clinical Trials by Nikolas Naleid, Amit Mahipal, Sakti Chakrabarti

“…The most prevalent grade 3 or higher irAEs were hepatitis (3.6%), pneumonitis (0.8%), and colitis (0.7%). Death attributed to irAEs was infrequent (0.9%). …”
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The Prevalence of Headache in Crohn’s Disease: Single-Center Experience by Ulker Anadol Kelleci, Turan Calhan, Abdurrahman Sahin, Resul Kahraman, Kamil Ozdil, Haci Mehmet Sokmen, Destina Yalcin

“…Patients in Crohn’s disease group were diagnosed and monitored according to European Crohn’s and Colitis Organization diagnostic criteria. The control group composed of healthy subjects with similar age and sex to Crohn’s disease group. …”
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Colonic Abnormalities in Manitoban Children with Helicobacter pylori Gastritis by Upama Banik, Camelia Stefanovici, Jennifer Griffin, Wael El-Matary

“…Twenty-two (59%) of 37 children who had colonoscopy had significant endoscopic and histopathological findings on colonoscopy including polyposis and colitis. Boys with colonic changes were diagnosed at an earlier age compared to those without (11.5 ± 7.0 versus 15.0 ± 2.0, p<0.049). …”
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Fecal Lactoferrin: Reliable Biomarker for Intestinal Inflammation in Pediatric IBD by Stephan Buderus, James H. Boone, Michael J. Lentze

“…Three patient groups were determined: n=21 (mean age 13.2) with Crohn’s disease (CD), n=15 (mean age 10.9) with ulcerative colitis (UC), and n=20 (mean age 11.9) in whom IBD was ruled out. …”
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Inflammatory Bowel Disease in Hispanics: The University of Puerto Rico IBD Registry by Esther A. Torres, Abdiel Cruz, Mariola Monagas, Marina Bernal, Yadira Correa, Rafael Cordero, Víctor L. Carlo

“…A registry of patients with inflammatory bowel diseases, ulcerative colitis (UC) and Crohn's disease (CD), was created at the University of Puerto Rico in 1995. …”
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Lymphocyte levels in Crohn’s disease patients in clinical remission are significantly lower than those in healthy people by Asi He, Tulan Hu, Linzhen Li

“…Patients and methods A total of 94 Crohn’s disease (CD) and 20 ulcerative colitis (UC) patients were included in this study. …”
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Disseminated Gastrointestinal Basidiobolomycosis: A Case Report with Review of Diagnostic Clues by Neda Soleimani, Mohammad Hossein Anbardar, Hamed Nikoupour, Faranak Derakhshan, Mojtaba Shafiekhani, Sahand Mohammadzadeh, Seyed Mohamad Sakhaei, Mahsa Farhadi

“…A colonoscopy showed an ulcerative lesion in the descending colon, and the biopsy was in favor of ulcerative colitis. Despite immunosuppressive treatment, there was no improvement, and with worsening symptoms, more investigations revealed advanced colon mass with entrapment of the stomach and pancreas. …”
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The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study by Sijia Sun, Jie Li, Mengxian Sun, Jie He, Songtao Tan, Ge Wang, Yuan Zheng, Xiaoping Fan

“…Additionally, there was no evidence to suggest that AA may increase the risk of inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC), systemic lupus erythematosus (SLE), and psoriasis (PSO). …”
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Pharmacokinetic Properties of Baitouweng Decoction in Bama Miniature Pigs: Implications for Clinical Application in Humans by Qianqian Xu, Huilan Gao, Fuqiang Zhu, Wenliang Xu, Yubo Wang, Jinwen Xie, Guangjun Guo, Limei Yang, Li Ma, Zhiqiang Shen, Jichang Li

“…For instance, the administration of Baitouweng decoction (BTWD) has proven effective in the treatment of ulcerative colitis. However, the limited understanding of its pharmacokinetics (PK) has impeded its widespread use. …”
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Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis by Feray Gençer Bingöl, Duygu Ağagündüz, Ferenc Budán

“…Additionally, p40 and p75 proteins exhibit protective effects on intestinal epithelial tight junctions, suggesting their therapeutic potential in preventing intestinal damage and diseases such as colitis. HM0539 enhances intestinal barrier integrity, exhibits antiinflammatory properties, and protects against bacterial infection, suggesting its possible as a therapeutic for inflammatory bowel disease. …”
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The Stability-Indicating Ultra High-Performance Liquid Chromatography with Diode Array Detector and Tandem Mass Spectrometry Method Applied for the Forced Degradation Study of Ritl... by Jelena Kovačić, Daniela Amidžić Klarić, Nikša Turk, Željko Krznarić, Emma Riordan, Ana Mornar

“…Background/Objectives: Janus kinase inhibitors open new horizons for small-molecule drugs in treating inflammatory bowel disease, with ritlecitinib demonstrating significant efficacy in clinical trials for ulcerative colitis and Crohn’s disease. Ritlecitinib, a second-generation JAK3 inhibitor, is a novel therapeutic agent for alopecia areata and other autoimmune conditions. …”
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Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases by Camilla de Almeida Martins, Ana Elisa Rabe Caon, Carolina Bortolozzo Graciolli Facanali, Carlos Walter Sobrado, Sergio Carlos Nahas, Rosa Maria Rodrigues Pereira, Reuma Margalit-Yehuda, Uri Kopylov, Natalia Sousa Freitas Queiroz

“…Overall, five patients had Crohn’s disease (DC) and two had ulcerative colitis (UC), and they were mostly female and non-Asian. …”
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Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro by Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang

“…Abstract Background Macrophages play an important role in the pathogenesis of ulcerative colitis (UC). We will explore the effects of sodium butyrate (SB) on macrophage function. …”
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To Bind or to Let Loose: Effectiveness of Sodium Polystyrene Sulfonate in Decreasing Serum Potassium by Shaifali Sandal, Hatim Karachiwala, John Noviasky, Dongliang Wang, William C. Elliott, David F. Lehmann

“…Thirteen deaths were noted in our cohort, of which one death was due to ischemic colitis. Conclusion. We conclude that sodium polystyrene sulfonate is effective in lowering serum potassium.…”
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PPARγ and the Innate Immune System Mediate the Resolution of Inflammation by Amanda Croasdell, Parker F. Duffney, Nina Kim, Shannon H. Lacy, Patricia J. Sime, Richard P. Phipps

“…These effects contribute towards the attenuation of multiple disease states, including COPD, colitis, Alzheimer’s disease, and obesity in animal models. …”
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The Relationship between Serum Bilirubin and Inflammatory Bowel Disease by Xiaojing Zhao, Linzhen Li, Xueting Li, Jiajia Li, Di Wang, Hongjie Zhang

“…We conducted a retrospective study with a total of 242 consecutive patients with Crohn’s disease (CD) and 211 consecutive patients with ulcerative colitis (UC). The Crohn’s Disease Activity Index (CDAI) score was used to assess disease activity in patients with CD and the Mayo score of patients with UC. 255 clinically healthy subjects comprised the control group, which come from the same geographic area as the IBD group. …”
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Diagnostic Role of Colon Capsule Endoscopy in Patients with Optimal Colon Cleaning by Ümit Akyüz, Yusuf Yılmaz, Ali Tüzün İnce, Bülent Kaya, Cengiz Pata

“…The CCE findings were as follows in 28 patients who were also examined with colonoscopy: polyp (range: 5–10 mm) in 6 patients, internal hemorrhoids in 3 patients, angiodysplasia in 1 patient, diverticula in 1 patient, and ulcerative colitis in 1 patient. The sensitivity, specificity, PPV, and NPV of CCE were 100%, 92%, 93%, and 100%, respectively. …”
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