Rare Case Studies of Bilateral and Symmetric Sacroiliac Disease by Stephen Soloway, Alyxandra M. Soloway, Tyler G. Chin, Timothy Lieske

“…We present three rare conditions presenting with bilateral and symmetric SIJ disease, none of which is ankylosing spondylitis, Crohn’s colitis, ulcerative colitis, psoriatic arthritis, and reactive arthritis (Reiter syndrome); there are reports of concurrent SIJ disease in rheumatoid arthritis and SLE. …”
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Clinical Experience with 5-Aminosalicylate Preparations in Inflammatory Bowel Disease - A Review by C.N. Williams

“…The efficacy of 5-ASA tablets is around 65 co 70% in patients with active ulcerative colitis, whereas the efficacy of the rectal preparations approach 100% when the treatment is for active distal disease. …”
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Crohn’s Disease: Advise and Consent by Bruce E Sands, Paul C Adams

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Overview of 5-ASA in Therapy of Inflammatory Bowel Disease by CN Williams

“…The multiplicity of action is probably its strength because drugs that have only one of these actions are relatively ineffective in inflammatory bowel disease. 5-ASA compounds are effective in treating mild to moderate acute ulcerative colitis and in maintaining remission, and are equivalent to sulfasalazine in this regard. 5-ASA used topically in enema or suppository form is highly efficient in both acute disease and in maintaining remission. 5-ASA is also effective in active Crohn’s disease, but not as effective as in maintenance therapy compared with ulcerative colitis. …”
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Update of Immunomodulatory Therapy for Inflammatory Bowel Disease by Charles N Bernstein

“…Intravenous cyclosporine is efficacious in acute severe ulcerative colitis and can settle active disease within days of administration. …”
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A Canadian Working Group Report on Fecal Microbial Therapy: Microbial Ecosystems Therapeutics by Emma Allen-Vercoe, Gregor Reid, Norman Viner, Gregory B Gloor, Susy Hota, Peter Kim, Christine Lee, Kieran C O’Doherty, Stephen J Vanner, J Scott Weese, Elaine O Petrof

“…A working group from across Canada comprised of clinician and basic scientists, epidemiologists, ethicists, Health Canada regulatory authorities and representatives of major funding agencies (Canadian Institutes of Health Research and the Crohn’s and Colitis Foundation of Canada) met to review the current experience with fecal microbial therapy and to identify the key areas of study required to move this field forward. …”
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The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues by Xin Xu, Hirokazu Fukui, Ying Ran, Xuan Wang, Yoshihito Inoue, Nobuhiko Ebisudani, Heihachiro Nishimura, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroshi Kiyama, Hiroto Miwa

“…The link between type III Reg and STAT3-associated cytokines appears to play a pivotal role in the pathophysiology of DSS-induced colitis.…”
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Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases by M. V. Kruchinina, M. F. Osipenko, A. I. Valuyskikh, E. Yu. Valuiskikh, I. O. Svetlova

“…In 48 additionally examined patients with IBD in remission (25 patients with ulcerative colitis, 15 — with Crohn’s disease, 8 — with unclassified colitis), the course of the disease was monitored over the next 12 months. …”
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<i>Сlostridium difficile</i> Infection in a COVID-19 Patient by A. A. Timofeeva, Yu. O. Shulpekova, V. M. Nechaev, M. R. Skhirtladze

“…Patients with COVID-19 are at risk of clostridial colitis due to massive antibiotic, systemic glucocorticoid and biologics-based therapy they receive. …”
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Empyema Caused by Clostridium difficile by Darren A Hudson, A Patrick Gibb, M John Gill

“…A case of empyema caused by aspiration of C difficile in a patient with carcinoid syndrome and C difficile colitis is described.…”
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Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages by Yanxia Fu, Jun Li, Mengdi Li, Junfeng Xu, Zheng Rong, Fangli Ren, Yinyin Wang, Jianqiu Sheng, Zhijie Chang

“…Indeed, HUC-MSCs dramatically ameliorated the disease symptoms and pathological changes of DSS-induced colitis mice. We deciphered the mechanism that HUC-MSCs inhibited tumorigenesis through reducing the proportion of macrophages, which were decreased in the mice suffered from AOM/DSS-induced colon cancer. …”
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A Case of In-Bore Transperineal MRI-Guided Prostate Biopsy of a Patient with Ileal Pouch-Anal Anastomosis by Michael Kongnyuy, Thomas Frye, Arvin K. George, Amichai Kilchevsky, Amogh Iyer, Meet Kadakia, Akhil Muthigi, Baris Turkbey, Brad J. Wood, Peter A. Pinto

“…Ulcerative colitis (UC) is an inflammatory disease that specifically affects the colon. …”
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Oral Contraceptives, Sex, Pregnancy and Breast Feeding in Inflammatory Bowel Disease by RN Allan

“…The information should be reinforced by simple, concise, clear information booklets, such as those produced by the National, Association for Colitis and Crohn's Disease.…”
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Outcome of Toxic Megacolon during Pregnancy by Carl Chartrand-Lefebvre, Jacques Heppell, Claude Potvin, Richard Clermont, Alfons Pomp

“…Two patients with ulcerative colitis required subtotal colectomy and ileostomy for toxic megacolon during pregnancy. …”
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Medical Management of Inflammatory Bowel Disease among Canadian Gastroenterologists by J Jones, R Panaccione, ML Russell, R Hilsden

“…BACKGROUND: Little is known about physician perceptions of and practices in using infliximab – a biological agent that was approved in Canada for the treatment of Crohn’s disease in 2001, and for ulcerative colitis in 2006.…”
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Meeting Report: Research Topics in Gastrointestinal Disease IX by Nicola Jones, Ken Croitoru, Stephen Vanner, George Tolomiczenko, Paul Belanger, Louise Hope

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Very Early-Onset Inflammatory Bowel Disease (VEO-IBD) Presenting with Recurrent Leukocytoclastic Vasculitis Preceded by Streptococcal Pharyngitis by Ashley Fonseca, Julee Sunny, Lina M. Felipez

“…Association between LV and ulcerative colitis (UC) is not commonly seen. We report a case of a 6-year-old female with a VEO-IBD UC phenotype presenting with multiple episodes of leukocytoclastic vasculitis, each preceded by streptococcal pharyngitis. …”
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A multi-omics spatial framework for host-microbiome dissection within the intestinal tissue microenvironment by Bokai Zhu, Yunhao Bai, Yao Yu Yeo, Xiaowei Lu, Xavier Rovira-Clavé, Han Chen, Jason Yeung, Dingani Nkosi, Jonathan Glickman, Antonio Delgado-Gonzalez, Georg K. Gerber, Mike Angelo, Alex K. Shalek, Garry P. Nolan, Sizun Jiang

“…We demonstrate MicroCart by investigating gut host and microbiome changes in a murine colitis model, using spatial proteomics, transcriptomics, and glycomics. …”
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Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient by Evgeni Brotfain, Leonid Koyfman, Amit Frenkel, Jochanan G. Peiser, Abraham Borer, Benjamin F. Gruenbaum, Alexander Zlotnik, Moti Klein

“…Unrecognized severe pseudomembranous colitis may become life threatening. A typical Clostridium difficile infection is associated with involvement of the colon; however, small bowel disease has also been described. …”
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Successful Therapy of Refractory Erythema Nodosum Associated with Crohn's Disease Using Potassium Iodide by John K Marshall, E Jan Irvine

“…This report describes successful treatment of severe, refractory erythema nodosum associated with Crohn's colitis using oral potassium iodide. While the mechanism of action of this agent is poorly understood, it appears to be an effective and nontoxic therapy for Crohn's-related erythema nodosum and warrants further evaluation in a placebo controlled trial.…”
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