Similar Clinical and Surgical Outcomes Achieved with Early Compared to Late Anti-TNF Induction in Mild-to-Moderate Ulcerative Colitis: A Retrospective Cohort Study by Christopher Ma, Candace L. Beilman, Vivian W. Huang, Darryl K. Fedorak, Karen Wong, Karen I. Kroeker, Levinus A. Dieleman, Brendan P. Halloran, Richard N. Fedorak

“…Biologic agents targeting tumor necrosis factor alpha are effective in the management of ulcerative colitis (UC), but their use is often postponed until after failure of other treatment modalities. …”
Get full text

Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF-κB Pathway Inhibition in Mice by Zhen Ni, Hao Li, Dong Mu, Juanni Hou, Xiaoyan Liu, Shanhong Tang, Shumei Zheng

“…Rapamycin protects against colitis through induction of autophagy, thus inhibiting the activation of NF-κB pathway and secretion of TNF-α.…”
Get full text

Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review by Michalina Jurkiewicz, Karolina Siembab, Julia Białeta, Katarzyna Rowińska, Agnieszka Napieralska, Wiktor Garbarczyk, Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Wiktoria Pysiewicz

Subjects: Get full text

Clinical and laboratory characteristics of solitary rectal ulcer syndrome: a retrospective analysis of 36 case by Furkan Ali Uygur, Muhammed Emin Göktepe, Gökhan Aydın, Enes Ağırman, Ahmet Cumhur Dülger

Subjects: Get full text

The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease by Paulina Jakubczyk, Piotr Widera, Justyna Helis, Maciej Michalik, Aleksandra Buczek, Hubert Bigajski, Aleksandra Banaś, Olga Bilczewska, Wiktoria Janik, Marta Handschuh

Subjects: Get full text

Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

Subjects: “…ulcerative colitis…”
Get full text

Antibiotic-associated diarrhea: state-of-the-art by D. V. Piliev, S. I. Achkasov, T. K. Korneva, O. I. Sushkov

Subjects: Get full text

Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases by A. S. Tertychnyy, Kh. M. Akhriyeva, E. A. Kogan, O. V. Zayratyants, L. S. Selivanova

Subjects: Get full text

Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance by Sandra Bermúdez-Sánchez, Palle Bager, Jens Frederik Dahlerup, Simon Mark Dahl Baunwall, Tine Rask Licht, Martin Steen Mortensen, Christian Lodberg Hvas

Subjects: Get full text

Development and validation of a nomogram for predicting immune-mediated colitis in lung cancer patients treated with immune checkpoint inhibitors: a retrospective cohort study in China by Qianjie Xu, Xiaosheng Li, Yuliang Yuan, Guangzhong Liang, Zuhai Hu, Wei Zhang, Ying Wang, Haike Lei

“…BackgroundThe increasing utilization of immune checkpoint inhibitors (ICIs) has led to a concomitant rise in the incidence of immune-related adverse events (irAEs), notably immune-mediated colitis (IMC). This study aimed to identify the clinical risk factors associated with IMC development in patients with lung cancer and to develop a risk prediction model to facilitate personalized treatment and care strategies.MethodsThe data collected included 21 variables, including sociodemographic characteristics, cancer-related factors, and routine blood markers. …”
Get full text

Effects of Ginkgo biloba Extract on Inflammatory Mediators (SOD, MDA, TNF-α, NF-κBp65, IL-6) in TNBS-Induced Colitis in Rats by Yan-Hong Zhou, Jie-Ping Yu, Yi-Fei Liu, Xiao-Jun Teng, Mei Ming, Peng Lv, Ping An, Shi-Quan Liu, Hong-Gang Yu

“…Inflammatory mediators play a criticial role in ulcerative colitis immune and inflammatory processes. The aim of the study was to investigate the effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-α, NF-κBp65, IL-6) in TNBS-induced colitis in rats. …”
Get full text

Fucoidan alleviated colitis aggravated by fiber deficiency through protecting the gut barrier, suppressing the MAPK/NF-κB pathway, and modulating gut microbiota and metabolites by Weiyun Zheng, Shuangru Tang, Xiaomeng Ren, Xiaomeng Ren, Shuang Song, Shuang Song, Chunqing Ai, Chunqing Ai

“…This study showed that dietary fiber deficiency enhanced the susceptibility of mice to colitis, which could be attributed to the disruption of the gut barrier integrity, activation of the NF-κB pathway, and oxidative stress. …”
Get full text

Dual Biologic or Small Molecule Therapy in Pediatric Inflammatory Bowel Disease: A Single Center Experience by Cheng Guo, Jin Zhou, Guoli Wang, Jie Wu

Subjects: Get full text

Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital by Ieva Renata Jonaitytė, Vita Karpavičiūtė, Gediminas Kiudelis, Juozas Kupčinskas, Laimas Jonaitis

Subjects: “…ulcerative colitis…”
Get full text

Medical and social rehabilitation of patients and disabled persons with inflammatory bowel diseases by K. A. Velikolug, Ye. K. Baranskaya, Zh. M. Sizova

Subjects: “…ulcerative colitis…”
Get full text

Substantiation of application and estimation of efficacy of probiotics at inflammatory bowel diseases by Ye. A. Poluektova, Yu. O. Sidorina, S. Yu. Kuchumova, A. V. Korolev, O. S. Shifrin

Subjects: Get full text

Analysis of risk factors of Clostridioides difficile infection in patients with inflammatory bowel disease by Alicja Jakubowska, Dorota Szydlarska, Grażyna Rydzewska

Subjects: Get full text

Murine DX5+NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4+CD62Lhigh T Cells through Fas Ligand by Jens M. Werner, Michael Damian, Stefan A. Farkas, Hans J. Schlitt, Edward K. Geissler, Matthias Hornung

“…It has been previously shown that immunoregulatory DX5+NKT cells are able to prevent colitis induced by CD4+CD62Lhigh T lymphocytes in a SCID mouse model. …”
Get full text

Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

Subjects: Get full text

Relieving Effect of <i>Artemisia ordosica Krasch</i> Extract on DSS-Induced Colitis by Regulating Immunity, Antioxidant Function, Gut Microbiota, and Bile Acid Metabolism in Mice by Min Jiang, Xuekai Zhang, Xiao Jin, Binlin Shi, Yuanqing Xu, Zheqi Wang

Subjects: Get full text