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861
Representation of Fictional Characters with Disabilities in Selected Crime Novels of Oͅládèͅjoͅ Òkédìjí
Published 2023-05-01“…The findings of the study showed that Òkédìjí represents the blind and cognitively impaired persons in a positive manner through his modes of projected characterization. …”
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862
A Comprehensive Analysis of Fibromyalgia and the Role of the Endogenous Opioid System
Published 2025-01-01“…Fibromyalgia represents a chronic pain disorder characterized by musculoskeletal pain, fatigue, and cognitive impairments. The exact mechanisms underlying fibromyalgia remain undefined; as a result, diagnosis and treatment present considerable challenges. …”
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863
Age-Related Decline in Controlled Retrieval: The Role of the PFC and Sleep
Published 2012-01-01“…Age-related cognitive impairments often include difficulty retrieving memories, particularly those that rely on executive control. …”
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864
Brain Reward System and Its Volumetric Investigations in Alcohol Addiction
Published 2024-12-01“…It is an indication that structural changes play a role in the etiology of cognitive impairments commonly seen in alcohol use disorder.…”
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865
A Proposed Role for Lymphatic Supermicrosurgery in the Management of Alzheimer's Disease: A Primer for Reconstructive Microsurgeons
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866
From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
Published 2012-01-01“…A wide variety of evidence from studies on DS individuals and mouse models of DS indicates that synaptic plasticity is adversely affected in human trisomy 21 and mouse segmental trisomy 16, respectively, an outcome that almost certainly extensively contributes to the cognitive impairments associated with DS. In this review, we will highlight some of the neurophysiological changes that we believe reduce the ability of trisomic neurons to undergo neuroplasticity-related adaptations. …”
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867
The gut microbiome, immune modulation, and cognitive decline: insights on the gut-brain axis
Published 2025-01-01“…A noteworthy correlation has been identified between imbalances in the gut microbiome and cognitive impairments, suggesting novel pathways for the treatment of cognitive disorders. …”
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868
Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism
Published 2025-01-01“…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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869
Cognitive Function in Parkinson’s Disease Patients with and without Anxiety
Published 2016-01-01“…Previous reports have noted that neuropsychiatric symptoms impair cognitive performance in PD patients; however, to date, no study has directly compared PD patients with and without anxiety to examine the impact of anxiety on cognitive impairments in PD. This study compared cognitive performance across 50 PD participants with and without anxiety (17 PDA+; 33 PDA−), who underwent neurological and neuropsychological assessment. …”
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870
Profile of cognitive deficits among children residing in areas with high ambient air pollution in Odisha
Published 2024-12-01“…While prior research has explored the association between air pollution and cognitive impairments, it is poorly studied in the Indian population. …”
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871
A Data Mining Approach for Visual and Analytical Identification of Neurorehabilitation Ranges in Traumatic Brain Injury Cognitive Rehabilitation
Published 2015-01-01“…Cognitive rehabilitation (CR) has become the treatment of choice for cognitive impairments after TBI. It consists of hierarchically organized tasks that require repetitive use of impaired cognitive functions. …”
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872
The Experience of Patients with Schizophrenia Treated with Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations
Published 2013-01-01“…A phenomenological approach was used and modified to involve some predetermined data structuring to accommodate for expected cognitive impairments of participants and the impact of rTMS on auditory hallucinations. …”
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873
Engagement in computerized cognitive training instructions by older people. A within-subject design to evaluate comprehension and acceptability of serious games instructions
Published 2025-02-01“…This research offers valuable insights into methodological strengths that can be applied in future studies to improve the usability and acceptance of CCT tools for older adults without cognitive impairments.…”
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874
Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice
Published 2025-02-01“…Utilizing APPswe/PSEN1dE9 (APP/PS1) mice, we investigated neurophysiological mechanisms underlying AD-associated cognitive impairments by assessing place cell activities in CA1 and CA3 hippocampal subregions, which have distinct yet complementary computational roles. …”
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875
Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models
Published 2025-02-01“…While APPSAA mice have been shown to develop progressive Aβ pathology and neuroinflammation, the age at which behavioral and cognitive impairments begin to develop has yet to be described. …”
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876
The Efficiency of Chitosan Against Tert Butylhydroquinone (TBHQ)-Induced Neurobehavioral Changes and Toxicity Effects in Male Rats
Published 2025-01-01“…Results: TBHQ exposure led to significant cognitive impairments and increased oxidative stress, marked by elevated malondialdehyde (MDA) and decreased superoxide dismutase (SOD) and glutathione (GSH) levels. …”
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877
Feasibility of Dual-Task Gait Training for Community-Dwelling Adults after Stroke: A Case Series
Published 2014-01-01“…Individuals with a combination of physical and cognitive impairments may not be appropriate for dual-task gait training.…”
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878
Impact of childhood trauma on cognitive function in patients with bipolar disorder
Published 2025-01-01“…BackgroundPatients with bipolar disorder (BD) frequently exhibit cognitive impairments. However, the association between childhood trauma as a risk factor for BD and cognitive deficits remains ambiguous.ObjectiveTo investigate the relationship between childhood trauma and cognitive function among patients with BD.MethodsThe study included 90 patients with BD and 94 healthy controls (HC). …”
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879
Top-Down Computerized Cognitive Remediation in Schizophrenia: A Case Study of an Individual with Impairment in Verbal Fluency
Published 2015-01-01“…The objective of this case study was to assess the specific effect of cognitive remediation for schizophrenia on the pattern of cognitive impairments. Case A is a 33-year-old man with a schizophrenia diagnosis and impairments in visual memory, inhibition, problem solving, and verbal fluency. …”
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880
Enhancing quality of care for older adults: The age‐friendly health system (4Ms framework) and the role of general medicine physicians as system‐based complexologists
Published 2025-01-01“…Older adults often experience multimorbidity, cognitive impairments, and physical frailties, increasing healthcare utilization and costs. …”
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