Showing 861 - 880 results of 936 for search '"cognitive impairment"', query time: 0.08s Refine Results
  1. 861

    Representation of Fictional Characters with Disabilities in Selected Crime Novels of Oͅládèͅjoͅ Òkédìjí by Oͅlálérè Adéyeͅmí

    Published 2023-05-01
    “…The findings of the study showed that Òkédìjí represents the blind and cognitively impaired persons in a positive manner through his modes of projected characterization. …”
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    Article
  2. 862

    A Comprehensive Analysis of Fibromyalgia and the Role of the Endogenous Opioid System by Mario García-Domínguez

    Published 2025-01-01
    “…Fibromyalgia represents a chronic pain disorder characterized by musculoskeletal pain, fatigue, and cognitive impairments. The exact mechanisms underlying fibromyalgia remain undefined; as a result, diagnosis and treatment present considerable challenges. …”
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    Article
  3. 863

    Age-Related Decline in Controlled Retrieval: The Role of the PFC and Sleep by Kristine A. Wilckens, Kirk I. Erickson, Mark E. Wheeler

    Published 2012-01-01
    “…Age-related cognitive impairments often include difficulty retrieving memories, particularly those that rely on executive control. …”
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  4. 864

    Brain Reward System and Its Volumetric Investigations in Alcohol Addiction by Muhammed Fatih Tabara, Murad Atmaca, Hanefi Yıldırım, Onur Solmaz, Muhammed Amir Essibayi, Mehmet Gürkan Gurok

    Published 2024-12-01
    “…It is an indication that structural changes play a role in the etiology of cognitive impairments commonly seen in alcohol use disorder.…”
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  5. 865

    A Proposed Role for Lymphatic Supermicrosurgery in the Management of Alzheimer's Disease: A Primer for Reconstructive Microsurgeons by Joon Pio Hong, Wei F. Chen, Dung H. Nguyen, Qingping Xie

    “…Evidence is building that suggests disease progression in AD and other cognitive impairments could be explained by dysfunction in the brain's lymphatic system or obstruction of drainage. …”
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    Article
  6. 866

    From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome by Nathan Cramer, Zygmunt Galdzicki

    Published 2012-01-01
    “…A wide variety of evidence from studies on DS individuals and mouse models of DS indicates that synaptic plasticity is adversely affected in human trisomy 21 and mouse segmental trisomy 16, respectively, an outcome that almost certainly extensively contributes to the cognitive impairments associated with DS. In this review, we will highlight some of the neurophysiological changes that we believe reduce the ability of trisomic neurons to undergo neuroplasticity-related adaptations. …”
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    Article
  7. 867

    The gut microbiome, immune modulation, and cognitive decline: insights on the gut-brain axis by Ruyi Zhang, Ruyi Zhang, Ning Ding, Xicui Feng, Wenli Liao

    Published 2025-01-01
    “…A noteworthy correlation has been identified between imbalances in the gut microbiome and cognitive impairments, suggesting novel pathways for the treatment of cognitive disorders. …”
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  8. 868

    Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism by Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek

    Published 2025-01-01
    “…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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  9. 869

    Cognitive Function in Parkinson’s Disease Patients with and without Anxiety by K. A. Ehgoetz Martens, J. Y. Y. Szeto, A. J. Muller, J. M. Hall, M. Gilat, C. C. Walton, S. J. G. Lewis

    Published 2016-01-01
    “…Previous reports have noted that neuropsychiatric symptoms impair cognitive performance in PD patients; however, to date, no study has directly compared PD patients with and without anxiety to examine the impact of anxiety on cognitive impairments in PD. This study compared cognitive performance across 50 PD participants with and without anxiety (17 PDA+; 33 PDA−), who underwent neurological and neuropsychological assessment. …”
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  10. 870

    Profile of cognitive deficits among children residing in areas with high ambient air pollution in Odisha by Kulumina Dash, Pratap Kumar Jena, Jigyansa Ipsita Pattnaik, Sayali Mishra, Jayaprakash Russell Ravan

    Published 2024-12-01
    “…While prior research has explored the association between air pollution and cognitive impairments, it is poorly studied in the Indian population. …”
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    Article
  11. 871

    A Data Mining Approach for Visual and Analytical Identification of Neurorehabilitation Ranges in Traumatic Brain Injury Cognitive Rehabilitation by Alejandro García-Rudolph, Karina Gibert

    Published 2015-01-01
    “…Cognitive rehabilitation (CR) has become the treatment of choice for cognitive impairments after TBI. It consists of hierarchically organized tasks that require repetitive use of impaired cognitive functions. …”
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  12. 872

    The Experience of Patients with Schizophrenia Treated with Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations by Priya Subramanian, Amer Burhan, Luljeta Pallaveshi, Abraham Rudnick

    Published 2013-01-01
    “…A phenomenological approach was used and modified to involve some predetermined data structuring to accommodate for expected cognitive impairments of participants and the impact of rTMS on auditory hallucinations. …”
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  13. 873

    Engagement in computerized cognitive training instructions by older people. A within-subject design to evaluate comprehension and acceptability of serious games instructions by Christelle Nahas, Marc Gandit, Emmanuel Monfort

    Published 2025-02-01
    “…This research offers valuable insights into methodological strengths that can be applied in future studies to improve the usability and acceptance of CCT tools for older adults without cognitive impairments.…”
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    Article
  14. 874

    Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice by Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J. Kim, Jeiwon Cho, Yeowool Huh

    Published 2025-02-01
    “…Utilizing APPswe/PSEN1dE9 (APP/PS1) mice, we investigated neurophysiological mechanisms underlying AD-associated cognitive impairments by assessing place cell activities in CA1 and CA3 hippocampal subregions, which have distinct yet complementary computational roles. …”
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  15. 875

    Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models by Lisa Blackmer-Raynolds, Lyndsey D. Lipson, Isabel Fraccaroli, Ian N. Krout, Jianjun Chang, Timothy Robert Sampson

    Published 2025-02-01
    “…While APPSAA mice have been shown to develop progressive Aβ pathology and neuroinflammation, the age at which behavioral and cognitive impairments begin to develop has yet to be described. …”
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  16. 876

    The Efficiency of Chitosan Against Tert Butylhydroquinone (TBHQ)-Induced Neurobehavioral Changes and Toxicity Effects in Male Rats by Shahad Alahmadi, Mohammed Mufadhe Alanazi, Fawaz Alasmari, Wedad Saeed Al-Qahtani, Gadah Albasher

    Published 2025-01-01
    “…Results: TBHQ exposure led to significant cognitive impairments and increased oxidative stress, marked by elevated malondialdehyde (MDA) and decreased superoxide dismutase (SOD) and glutathione (GSH) levels. …”
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  17. 877

    Feasibility of Dual-Task Gait Training for Community-Dwelling Adults after Stroke: A Case Series by Prudence Plummer, Raymond M. Villalobos, Moira S. Vayda, Myriam Moser, Erin Johnson

    Published 2014-01-01
    “…Individuals with a combination of physical and cognitive impairments may not be appropriate for dual-task gait training.…”
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  18. 878

    Impact of childhood trauma on cognitive function in patients with bipolar disorder by Zhiyang Zhang, Zhiyang Zhang, Chenyu Zhou, Chenyu Zhou, Zhen Mao, Zhen Mao, Yue Sun, Yue Sun, Lei Zhao, Lei Zhao, Tian Li, Tian Li, Chuanyue Wang, Chuanyue Wang, Qijing Bo, Qijing Bo

    Published 2025-01-01
    “…BackgroundPatients with bipolar disorder (BD) frequently exhibit cognitive impairments. However, the association between childhood trauma as a risk factor for BD and cognitive deficits remains ambiguous.ObjectiveTo investigate the relationship between childhood trauma and cognitive function among patients with BD.MethodsThe study included 90 patients with BD and 94 healthy controls (HC). …”
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  19. 879

    Top-Down Computerized Cognitive Remediation in Schizophrenia: A Case Study of an Individual with Impairment in Verbal Fluency by Marjolaine Masson, Til Wykes, Michel Maziade, Clare Reeder, Marie-Anne Gariépy, Marc-André Roy, Hans Ivers, Caroline Cellard

    Published 2015-01-01
    “…The objective of this case study was to assess the specific effect of cognitive remediation for schizophrenia on the pattern of cognitive impairments. Case A is a 33-year-old man with a schizophrenia diagnosis and impairments in visual memory, inhibition, problem solving, and verbal fluency. …”
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  20. 880

    Enhancing quality of care for older adults: The age‐friendly health system (4Ms framework) and the role of general medicine physicians as system‐based complexologists by Masaya Higuchi, Takashi Watari, Kenya Ie

    Published 2025-01-01
    “…Older adults often experience multimorbidity, cognitive impairments, and physical frailties, increasing healthcare utilization and costs. …”
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    Article