Showing 741 - 760 results of 936 for search '"cognitive impairment"', query time: 0.07s Refine Results
  1. 741

    Patient-reported systemic symptoms in women with silicone breast implants: a descriptive cohort study by Karlinde Amber Spit, Miranda Scharff, Christel JM de Blok, Frank B Niessen, Yara Bachour, Prabath W Nanayakkara

    Published 2022-06-01
    “…Most frequently reported systemic symptoms at baseline included fatigue (88%), arthralgia (71%), morning stiffness (59%), myalgia (48%), cognitive impairment (33%), peripheral neurological symptoms (30%) and lymphadenopathy (22%). …”
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  2. 742

    Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study by Robert W Platt, Laurent Azoulay, Ying Cui, Christel Renoux, Oriana Hoi Yun Yu, Zarin Abdullah, Chenjie Xia

    Published 2025-01-01
    “…Objectives To assess the association between sodium-glucose co-transporter-2 inhibitor (SGLT-2i) use and the risk of incident dementia compared with dipeptidyl peptidase-4 inhibitors (DPP-4i) use among individuals with type 2 diabetes.Design A population-based retrospective cohort study.Setting The Clinical Practice Research Datalink (CPRD) Aurum database from the UK.Participants Individuals with type 2 diabetes, aged 40 years or older, newly prescribed SGLT-2i or DPP-4i on or after 2013–2021, registered in the CPRD Aurum database.Main outcome measure The primary outcome was incident dementia, and the secondary outcome was incident mild cognitive impairment (MCI). Cox proportional hazard models were used to estimate the HR and corresponding 95% CI for the primary and secondary outcomes. …”
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  3. 743

    Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

    Published 2025-01-01
    “…The final model was adjusted for sex, age, comorbidity, education, physical activity, and cognitive impairment.ResultsA total of 304 participants with two evaluations (baseline and follow-up) were included in the study. …”
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  4. 744

    Investigating ITM2B‐associated ataxia in a Taiwanese cerebellar ataxia cohort by Shih‐Yu Fang, Cheng‐Tsung Hsiao, Kang‐Yang Jih, Yu‐Sheun Tsai, Kuan‐Lin Lai, Cheng‐Ta Chou, Yi‐Chu Liao, Yi‐Chung Lee

    Published 2025-01-01
    “…Most participants had no cognitive impairment at symptom onset but experienced memory decline, oculomotor disturbances, lower limb spasticity, and extensor plantar responses within 2–5 years. …”
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  5. 745

    Amyloid-β and heart failure in Alzheimer’s disease: the new vistas by Hayder M. Al-Kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Sohaib G. Mohammed, Ali I. Al-Gareeb, Ali K. Albuhadily, Retaj A. Dawood, Amer Al Ali, Mohammed H. Abu-Alghayth

    Published 2025-02-01
    “…Aβ-induced neurodegeneration and associated neuroinflammation, oxidative stress, endoplasmic reticulum stress (ER), and mitochondrial dysfunction contribute to the development of cognitive impairment and dementia. Of note, Aβ is not only originated from the brain but also produced peripherally and, via the blood–brain barrier (BBB), can accumulate in the brain and result in the development of AD. …”
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  6. 746

    Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report by Elisa Dinoi, Giuseppe Daniele, Giuseppe Daniele, Angela Michelucci, Fulvia Baldinotti, Fabrizio Campi, Piero Marchetti, Stefano Del Prato, Angela Dardano, Angela Dardano

    Published 2025-02-01
    “…The patient was discharged on a basal-bolus insulin therapy managed by his parents due to his cognitive impairment. In spite of COVID-19 pandemic, the patient achieved tight glycemic control (HbA1c 41 mmol/mol) with non-severe hypoglycemic events in the face of significant body weight (BW) increase (+ 13 kg vs baseline). …”
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  7. 747

    Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

    Published 2025-01-01
    “…Subgroup analysis revealed that the effect size was non-significant for participants with mild cognitive impairment (MCI) (p = 0.08), while significant for participants with normal cognitive function (p < 0.01). …”
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  8. 748

    The research progress on effective connectivity in adolescent depression based on resting-state fMRI by Xuan Deng, Jiajing Cui, Jinyuan Zhao, Jinji Bai, Junfeng Li, Kefeng Li

    Published 2025-02-01
    “…We first introduce some common EC analysis methods, discuss their application background and specific characteristics.ResultsEC analysis reveals information flow problems between different brain regions, such as the default mode network, the central executive network, and the salience network, which are closely related to symptoms of depression, such as low mood and cognitive impairment. This review discusses the limitations of existing studies while summarizing the current applications of EC analysis methods. …”
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  9. 749

    Effects of Quetiapine on Novelty‐Related Object Recognition Memory and Hippocampal BDNF Level in Sleep‐Deprived Rats by Öznur Özge Özcan, Burcu Çevreli, Emel Serdaroğlu Kaşıkçı, Mesut Karahan, Muhsin Konuk

    Published 2025-01-01
    “…ABSTRACT Background The underlying mechanism of quetiapine (QET) in treating cognitive impairment in sleep deprivation is unclear. The present study aimed to evaluate the effects of treatment with QET on novel object recognition and hippocampal (hippo) brain‐derived neurotrophic factor (BDNF) levels in rats submitted to 72 h sleep deprivation (SD). …”
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  10. 750

    Correlation between Serum Platelet Count and Cognitive Function in Patients with Atrial Fibrillation: A Cross-Sectional Study by Dandan Sun, Quanliang Wang, Jie Kang, Jie Zhou, Ruijuan Qian, Wenqing Wang, Haichen Wang, Qingyun Zhang

    Published 2021-01-01
    “…Background. The risk of cognitive impairment in patients with atrial fibrillation is significantly increased. …”
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  11. 751

    Increased Growth Differentiation Factor 15 Levels Are Associated with HIV-Associated Neurocognitive Impairment: A Pilot Study by Ali Boustani, Mary K. Ford, Jacqueline R. Kulbe, Anna E. Laird, Leeann Shu, Matthew Spencer, Bryant Avalos, Kyle C. Walter, Ronald J. Ellis, Jerel Adam Fields

    Published 2025-01-01
    “…The strong association between GDF15 levels and cognitive impairment severity suggests its potential as a biomarker for the early detection and monitoring of NCI in PWH.…”
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  12. 752

    Cerebellar white and gray matter abnormalities in temporal lobe epilepsy: a voxel-based morphometry study by Yini Chen, Jingyu Pan, Andong Lin, Lu Sun, Yufei Li, Hongsen Lin, Renwang Pu, Ying Wang, Yiwei Qi, Bo Sun

    Published 2024-08-01
    “…Furthermore, it was observed that the MMSE was more effective than the MoCA in identifying epilepsy patients with cognitive impairment.ConclusionThis study supported previous research indicating that temporal lobe epilepsy (TLE) is linked to structural changes in the cerebellum, specifically affecting the volume of gray matter. …”
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  13. 753

    The development and validation testing of a comprehensive frailty assessment in women with breast cancer by Sheng-Miauh Huang, Ling-Ming Tseng, Chi-Cheng Huang, Pei-Ju Lien, Su-Chen Fang, Yinhui Hong

    Published 2025-02-01
    “…The factors were interpreted as (1) deterioration of body and mobility, (2) negative emotions, and (3) cognitive impairment. The goodness of fit indices of the confirmatory factor analysis were as follows: chi-square = 234.498 (p < 0.01), normed chi-square = 2.322, SRMR = 0.055, RMSEA = 0.08, CFI = 0.930, and LI = 0.917. …”
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  14. 754

    Large-Scale Neuronal Network Dysfunction in Diabetic Retinopathy by Xin Huang, Yan Tong, Chen-Xing Qi, Han-Dong Dan, Qin-Qin Deng, Yin Shen

    Published 2020-01-01
    “…There is accumulating evidence that specific functional and structural architecture changes in the brain are related to cognitive impairment in DR patients. However, little is known regarding whether the functional architecture of resting-state networks (RSNs) changes in DR patients. …”
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  15. 755

    Case report: Overlapping syndrome of MOG-IgG associated optic neuritis and autoimmune encephalitis with co-existence of anti-NMDAR and anti-GABABR antibodies by Zhujun Mei, Zhujun Mei, Zhujun Mei, Zhujun Mei, Jingguo Wang, Jingguo Wang, Junling Wang, Xiaoni Liu, Xiaoni Liu, Bo Deng, Bo Deng, Wenbo Yang, Wenbo Yang, Xiang Zhang, Xiang Zhang, Xiangjun Chen, Xiangjun Chen, Hai Yu, Hai Yu

    Published 2025-01-01
    “…The patient exhibited a constellation of symptoms, including vision loss, seizures, mental and behavioral disorders, cognitive impairment, and speech abnormalities. At the two-year follow-up, the patient’s symptoms had abated entirely. …”
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  16. 756

    Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction by Cathrin E. Hansen, Davide Vacondio, Lennart van der Molen, Annika A. Jüttner, Wing Ka Fung, Manon Karsten, Bert van het Hof, Ruud D. Fontijn, Gijs Kooij, Maarten E. Witte, Anton J. M. Roks, Helga E. de Vries, Inge Mulder, Nienke M. de Wit

    Published 2025-01-01
    “…Abstract Aging of the brain vasculature plays a key role in the development of neurovascular and neurodegenerative diseases, thereby contributing to cognitive impairment. Among other factors, DNA damage strongly promotes cellular aging, however, the role of genomic instability in brain endothelial cells (EC) and its potential effect on brain homeostasis is still largely unclear. …”
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  17. 757

    Peripapillary retinal nerve fiber layer and ganglion cell complex in Alzheimer’s disease by R.N. Gulieva

    Published 2020-06-01
    “…</i> </p> <p> <i><b>Patients and Methods: </b>45 patients (88 eyes) aged 58–74 years (mean age 66.2±3.44 years) with AD and mild cognitive impairment (10 men and 35 women) were examined. …”
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  18. 758

    Brain health in Norwegian female former top-level football players: a protocol for a longitudinal cohort study by Thor Einar Andersen, Roald Bahr, Emilie Isager Howe, Peter Filipcik, John Bjørneboe, Geir Selbaek, Sara Christina Dahlén, Stian Kirkerud Sandmo, Lena Bache-Mathisen, Einar August Høgestøl, Truls Straume-Næsheim, Lars T Westlye

    Published 2025-01-01
    “…Recent studies have identified an association between playing football at the top level and an elevated risk of cognitive impairment and neurodegenerative disease. However, these were conducted on men, and there is a knowledge gap regarding these risks in female athletes. …”
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  19. 759

    Static and dynamic brain functional connectivity patterns in patients with unilateral moderate-to-severe asymptomatic carotid stenosis by Junjun Wang, Junjun Wang, Linfeng Song, Binlin Tian, Li Yang, Xiaoyu Gu, Xu Chen, Lei Gao, Lin Jiang

    Published 2025-01-01
    “…Background and purposeAsymptomatic carotid stenosis (ACS) is an independent risk factor for ischemic stroke and vascular cognitive impairment, affecting cognitive function across multiple domains. …”
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  20. 760