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661
Early career teachers’ social and emotional competencies, self-efficacy and burnout: a mediation model
Published 2025-01-01“…Structural equation modelling was implemented to test models of hypothesised relations for the overall burnout as a dependent variable and for each burnout dimension: exhaustion, mental distance, cognitive impairment, and emotional impairment. Tested models singled out self-management and social awareness as two social and emotional competencies that are, along with teacher self-efficacy, particularly predictive of burnout. …”
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662
Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRI
Published 2025-01-01“…Results We observe that both intra-regional and inter-regional E-I balance is progressively disrupted from cognitively normal individuals, to mild cognitive impairment (MCI) and to AD. Also, we find that local inhibitory connections are more significantly impaired than excitatory ones and the strengths of most connections are reduced in MCI and AD, leading to gradual decoupling of neural populations. …”
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663
Clinical and Imaging Prognosis in Patients with Delayed Encephalopathy after Acute Carbon Monoxide Poisoning
Published 2020-01-01“…Except for the pathologically confirmed DEACMP, epileptic seizure, hemiplegia, and vegetative state, the remaining symptoms had been improved, especially the cognitive impairment, which had been decreased from 95% to 25% and psychiatric symptoms also decreased from 95% to 55% at the 6-month follow-up. …”
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664
The Diagnostic Role of Serum Inflammatory and Soluble Proteins on Dementia Subtypes: Correlation with Cognitive and Functional Decline
Published 2007-01-01“…However there are restricted data about the profile of the inflammatory and soluble proteins in well evaluated Alzheimer’s disease (AD), vascular dementia (VD), mild cognitive impairment (MCI) and healthy controls. There are also no reliable data regarding the relationship between the overlapping protein levels and cognitive or functional decline. …”
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665
Multi-protective effects of wheat embryo globulin on D-gal-induced aging mice
Published 2023-07-01“…These results effectively revealed that WEG not only improved the abilities of learning and memory, and the cognitive impairment, but also delayed the aging process of the D-gal-induced mice.…”
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666
Assessing the Inter-Rater and Inter-Trial Reliability of the NeurOptics Pupillary Light Response-3000 Pupillometer
Published 2025-02-01“… # Study Design: Observational, reliability study Methods: Forty-eight healthy adults (age 18-40 years) without a history of neurological injury, optical surgery, or cognitive impairment participated. Two independent raters used the NeurOptics PLR-3000 to measure PLR parameters in the left and right eyes of each subject. …”
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667
Non-Linear Effects of Acute Sleep Deprivation on Spatial Working Memory: Cognitive Depletion and Neural Compensation
Published 2024-12-01“…These findings highlight the non-linear nature of cognitive impairment due to sleep deprivation, involving complex self-regulatory and compensatory mechanisms, with implications for understanding cognitive resilience and adaptive processes.…”
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668
Effect of phototherapy on event-related potentials in patients with post-stroke depression through serum tetrahydrobiopterin level intervention: a clinical study
Published 2025-01-01“…Abstract Background This study investigated the effects of phototherapy on serum BH4 levels, evoked potentials, and cognitive impairment in post-stroke depression patients. …”
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669
Effect of neonatal dexamethasone treatment on cognitive abilities of adult male mice and gene expression in the hypothalamus
Published 2019-07-01“…Malfunction of the HPA axis as a result of activation of the glucocorticoid system in early life may cause the development of cognitive impairment in the adult mice.…”
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670
Early Diagnosis of Alzheimer’s Disease Using Adaptive Neuro K-Means Clustering Technique
Published 2025-01-01“…Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, behavioral changes, and impaired self-care, often preceded by Mild Cognitive Impairment (MCI). Not all MCI cases progress to AD, creating a diagnostic challenge. …”
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671
To Assess Caregiver Burden of Patients with Dementia: Its Sociodemographic and Clinical Correlates
Published 2024-01-01“…Dementia is a chronic neurodegenerative disorder that refers to a disease process marked by progressive cognitive impairment in clear consciousness. The morbidities associated with dementia accounts for the poor quality of life. …”
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672
Preclinical Cognitive Markers of Alzheimer Disease and Early Diagnosis Using Virtual Reality and Artificial Intelligence: Literature Review
Published 2025-01-01“…ObjectiveResearch emphasizes the significance of early detection in AD during the preclinical phase, which does not involve cognitive impairment but nevertheless requires reliable biomarkers. …”
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673
Advances in Stem Cell Therapy for Huntington’s Disease: A Comprehensive Literature Review
Published 2025-01-01“…Huntington’s disease (HD) is an inherited neurodegenerative disease characterized by uncontrolled movements, emotional disturbances, and progressive cognitive impairment. It is estimated to affect 4.3 to 10.6 per 100,000 people worldwide, and the mean prevalence rate among all published studies, reviews, and genetic HD registries is 5.7 per 100,000. …”
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674
Temporal ablation of the ciliary protein IFT88 alters normal brainwave patterns
Published 2025-01-01“…These afflictions are caused by disturbances in a wide variety of genes but a common phenotype amongst them is cognitive impairment. While cilia-mediated neural function has been widely examined in early neurodevelopment, their function in the adult brain is not well understood. …”
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675
IUPHAR Review: Alpha6-containing GABAA receptors – Novel targets for the treatment of schizophrenia
Published 2025-03-01“…This recently has been confirmed by demonstrating that positive allosteric modulators with high selectivity for α6GABAARs can reduce positive and negative symptoms and cognitive impairment of schizophrenia in several animal models of this disorder. …”
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676
Research progress on the mechanism and markers of metabolic disorders in the occurrence and development of cognitive dysfunction after ischemic stroke
Published 2025-01-01“…Post-stroke cognitive impairment (PSCI) is a common complication following a stroke that significantly affects patients’ quality of life and rehabilitation outcomes. …”
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677
Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review)
Published 2024-10-01“…An analysis of clinical studies in Ukraine shows that drugs based on B. monnieri can be used in the complex treatment of cognitive impairment associated with dyscirculatory encephalopathy in adults and perinatal CNS damage in children. …”
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678
Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease
Published 2025-01-01“…Transcriptome profiling, DNA methylation, and Sap130 ChIPseq analyses all demonstrate dysregulation of genes associated with autism and cognitive impairment. This includes perturbation of REST transcriptional regulation of neurogenesis, disruption of CREB signaling regulating synaptic plasticity, and defects in neurovascular coupling mediating cerebral blood flow. …”
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679
Spectrum-specific encephalography standardized low-resolution brain electromagnetic tomography network and gray matter correlations in vascular dementia patients
Published 2020-01-01“…The encephalography and neuroimaging data mining at different stages would bring neuromodulation strategies in practice; 15 mild cognitive impairment patients and 16 mild vascular dementia patients as well as 17 cognitive healthy controls were screened in this study. …”
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680
Understanding the Impact of Urinary Incontinence in Persons with Dementia: Development of an Interdisciplinary Service Model
Published 2021-01-01“…Our aim was to develop a dedicated urology service within a cognitive impairment clinic in order to treat and better understand the bothersome urinary symptoms suffered by persons with dementia. …”
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