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561
Experimental Study on the Central Mechanism of Penehyclidine Hydrochloride against Relapse Behavior in Morphine-Dependent Rats
Published 2022-01-01“…Results. 4 and 7 hours after administration, compared with group 1, the TchE activity increased and Ach level decreased in groups 2, 3, and 4 and the difference was significant (P<0.05), so the principle of penehyclidine hydrochloride against morphine-dependent rats is that penehyclidine hydrochloride causes cognitive impairment in the brain of mice, thereby achieving antimorphine effects.…”
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562
Fear of Falling among Elderly Individuals with Various Medical Conditions
Published 2025-01-01“…In Alzheimer`s disease with mild cognitive impairment, fear of falling indicators are almost indistinguishable from those of healthy individuals. …”
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563
Hybrid electroconvulsive therapy in an adolescent with major depressive disorder: a case report
Published 2025-01-01“…We tried to preserve the rapid relief of depressive symptoms in electroconvulsive therapy (ECT) while causing less cognitive impairment, thus designing the hybrid-ECT (HECT), a modified ECT therapy. …”
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564
Active Aging for Individuals with Parkinson’s Disease: Definitions, Literature Review, and Models
Published 2014-01-01“…Movement problems of PD affect physical activity, psychiatric symptoms lessen social communication, and cognitive impairment could worsen mental well-being in elderly with PD, all of which could lead to earlier retirement and poorer quality of life compared with healthy elderly. …”
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565
A Case of Cognitive Decline Resulting from Aging, Temporal Lobe Epilepsy, and Environmental Factors
Published 2019-01-01“…We diagnosed the patient with mild cognitive impairment and adjustment disorder with anxiety. …”
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566
Meeting the Challenge of Diabetes in Ageing and Diverse Populations: A Review of the Literature from the UK
Published 2016-01-01“…These provide a theoretical framework for future research to advance knowledge about concordance; culturally meaningful measures of depression and cognitive impairment; and care planning in different contexts which support effective diabetes care for aging and diverse populations.…”
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567
From Mechanisms to Medicine: Neurovascular Coupling in the Diagnosis and Treatment of Cerebrovascular Disorders: A Narrative Review
Published 2024-12-01“…Pathological conditions such as stroke, subarachnoid hemorrhage, cerebral small vascular disease, and vascular cognitive impairment can disrupt NVC even before clinical symptoms appear. …”
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568
Prevalent symptoms and characteristics of the Long COVID-19 population: a scoping review
Published 2025-02-01“…Results: an analysis of the 13 articles selected showed that Long COVID affects all age groups and people of both sexes, presenting a multiplicity of symptoms, such as fatigue (61.5%), dyspnea (46.1%), changes in smell and/or taste (38.6%), anxiety (15.3%) and cognitive impairment (30.7%). Females were found to be at increased risk of developing Long COVID. …”
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569
Limited research investigating the value of MRI in predicting future cognitive morbidity in survivors of paediatric brain tumours: A systematic-review and call to action for clinic...
Published 2025-01-01“…Reliable individual-level predictions regarding the likelihood, degree, and affected domains of cognitive impairment would be clinically beneficial. While established risk factors exist, quantitative MRI analysis may enhance predictive value, above and beyond current clinical risk models. …”
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570
Hip Fractures in Persons with Stroke
Published 2013-01-01“…Persons with fractures more often had impaired vision and cognitive impairment and more had had previous fractures. …”
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571
Current Status of Plant-Based Bioactive Compounds as Therapeutics in Alzheimer’s Diseases
Published 2025-01-01“…Alzheimer’s disease (AD) is a common central neurodegenerative disease disorder characterized primarily by cognitive impairment and non-cognitive neuropsychiatric symptoms that significantly impact patients’ daily lives and behavioral functioning. …”
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572
A Qualitative Study to Explore Ways to Observe Results of Engaging Activities in Clients with Dementia
Published 2017-01-01“…Many occupational therapists face the challenge of helping clients with dementia to select and perform meaningful occupations, which may be difficult due to cognitive impairment. Understanding tacit knowledge of well-experienced occupational therapists could positively affect occupational therapy practice for clients with dementia. …”
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573
Central Poststroke Pain: Its Profile among Stroke Survivors in Kano, Nigeria
Published 2017-01-01“…The study was a cross-sectional design involving stroke survivors who were ≥18 years old and with no significant cognitive impairment approved by the Research Ethics Committee of Aminu Kano Teaching Hospital. …”
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574
Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade
Published 2024-12-01“…Abstract Impaired muscle mitochondrial oxidative capacity is associated with future cognitive impairment, and higher levels of PET and blood biomarkers of Alzheimer’s disease and neurodegeneration. …”
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575
IMPLEMENTATION OF BRAIN GYM THERAPY IN ELDERLY WITH DEMENTIA EXPERIENCING MEMORY IMPAIRMENT AT UPTD GRIYA WREDA JAMBANGAN SURABAYA: CASE STUDY
Published 2024-09-01“…Results: The results of applying brain gym for 6 x 2 weeks with a duration of 5-10 minutes showed that there was an increase in the MMSE examination score, which was obtained with a value of 21 (moderate cognitive impairment). There is an increase in the orientation section of 3 points, remembering 1 point, and language 1 point. …”
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576
Alzheimer’s disease diagnosis by 3D-SEConvNeXt
Published 2025-01-01“…Subsequently, the preprocessed data is input into the 3D-SEConvNeXt network to perform four classification tasks: distinguishing between AD and Normal Control (NC), Mild Cognitive Impairment (MCI) and NC, AD and MCI, as well as AD, MCI, and NC. …”
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577
The intricate interplay between dietary habits and cognitive function: insights from the gut-brain axis
Published 2025-01-01“…This review underscores the potential of dietary interventions to prevent and mitigate cognitive impairment, ultimately aiming to improve quality of life.…”
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578
Dysfunction of G Protein-Coupled Receptor Kinases in Alzheimer's Disease
Published 2010-01-01“…The deficiency of GRK5, on the other hand, impairs presynaptic M2 autoreceptor desensitization, which leads to a reduced acetylcholine release, axonal/synaptic degenerative changes, and associated amnestic, mild cognitive impairment. It also promotes an evil cycle to further increase Beta-amyloid accumulation and exaggerates brain inflammation, possibly even the basal forebrain cholinergic degeneration. …”
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579
Crossroads of Neurology and Virology: The Neurological Manifestations of COVID-19
Published 2024-12-01“…Acute neurological manifestations include encephalitis, stroke, and Guillain-Barré syndrome, while long-term sequelae encompass cognitive impairment, neurodegeneration, and psychiatric disorders. …”
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580
Role of Thyroid Hormone in Neurodegenerative Disorders of Older People
Published 2025-01-01“…In addition, there is a significant association between thyroid hormone (TH) levels and the degree of cognitive impairment in Parkinson’s disease (PD). The pathophysiology of TH-related neurodegeneration include changes in the blood–brain barrier, increased cellular stress, altered processing of β-amyloid precursor protein and the effect of TH on neuronal cell viability. …”
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