Showing 501 - 520 results of 936 for search '"cognitive impairment"', query time: 0.07s Refine Results
  1. 501

    Effects of Gestational Inflammation with Postpartum Enriched Environment on Age-Related Changes in Cognition and Hippocampal Synaptic Plasticity-Related Proteins by Shi-Yu Sun, Xue-Yan Li, He-Hua Ge, Yu-Xin Zhang, Zhe-Zhe Zhang, Zhan-Qiang Zhuang, Chong-Yang Ren, Fang Wang, Gui-Hai Chen

    Published 2020-01-01
    “…Increasing evidence indicates that exposure to inflammation during pregnancy intensifies the offspring’s cognitive impairment during aging, which might be correlated with changes in some synaptic plasticity-related proteins. …”
    Get full text
    Article
  2. 502

    Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease by Jared M. Fine, Jacob Kosyakovsky, Tate T. Bowe, Katherine A. Faltesek, Benjamin M. Stroebel, Juan E. Abrahante, Michael R. Kelly, Elizabeth A. Thompson, Claire M. Westby, Kiley M. Robertson, William H. Frey, Leah R. Hanson

    Published 2025-01-01
    “…We and other research groups have shown that IN DFO rescues cognitive impairment in several rodent models of Alzheimer Disease (AD).MethodsThis study was designed to probe dosing regimens to inform future clinical trials, while exploring mechanisms within the intracerebroventricular (ICV) streptozotocin (STZ) model.ResultsFive weeks of daily IN dosing of Long Evans rats with 15 μL of a 1% (0.3 mg), but not 0.1% (0.03 mg), solution of DFO rescued cognitive impairment caused by ICV STZ administration as assessed with the Morris Water Maze (MWM) test of spatial memory and learning. …”
    Get full text
    Article
  3. 503

    Mortality of elder financial and psychological abuse victims in rural Malaysia: a prospective cohort study by Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo, Sajaratulnisah Othman, Rajini Sooryanarayana, Norliana Ismail, Sharifah Nor Ahmad, Inayah Abdul Razak, Devi Peramalah, Awang Bulgiba Awang Mahmud, Halima B Awang, Siti Zaharah Jamaludin, Jamali Samsuddin, Mohammad Mafrukhin Mokhtar, Syed Mohd Fauzi, Zainudin Mohd Ali

    Published 2022-07-01
    “…Individuals with severe cognitive impairment were excluded.Outcome measure Mortality data were provided by the Malaysian National Registration Department and linked to respondents’ national identification numbers. …”
    Get full text
    Article
  4. 504

    Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study) by Lotte Haverman, Eelco Franz, Ka Yin Leung, Albert Jan Van Hoek, Hans Knoop, Cees C van den Wijngaard, Elizabeth N Mutubuki, Tessa van der Maaden, Albert Wong, Anna D Tulen, Siméon de Bruijn

    Published 2022-07-01
    “…Common symptoms include fatigue, cognitive impairment and dyspnoea. However, knowledge regarding the nature and risk factors for developing persisting symptoms is still limited. …”
    Get full text
    Article
  5. 505

    Iron deposition is associated with motor and non-motor network breakdown in parkinsonism by Fangda Leng, Yue Gao, Fan Li, Luhua Wei, Yunchuang Sun, Fang Liu, Ying Zhu, Jianxing Qiu, Zhaoxia Wang, Yiwei Zhang

    Published 2025-01-01
    “…Impairment of cerebellar network and language network are associated with motor symptoms and cognitive impairment, respectively. Moreover, dysfunction of the networks is associated with iron deposition in deep nuclei (SN, DN, Putamen).…”
    Get full text
    Article
  6. 506

    Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation by Bo Ye, Tianzhu Tao, Andong Zhao, Liyuan Wen, Xiaofei He, Yi Liu, Qiang Fu, Weidong Mi, Jingsheng Lou

    Published 2019-01-01
    “…Sepsis-associated encephalopathy (SAE) is a poorly understood condition that leads to long-term cognitive impairment and increased mortality in survivors. …”
    Get full text
    Article
  7. 507

    Steroid-Responsive Encephalopathy Associated with Thyroiditis (SREAT): A Case Report of Saving a Young Female Life by Abdelrahman Mahmoud Senosy

    Published 2023-08-01
    “…Symptoms include altered mental status, seizures, and cognitive impairment. When diagnostic criteria are met, steroids are the cornerstone of treatment with a reported good response. …”
    Get full text
    Article
  8. 508

    Updating the Diagnosis and Management of Dementia. Practical Contributions in our Context by Ángel Julio Romero Cabrera, Eduardo Fernández Casteleiro, Julio López Argüelles, Julio Daniel Suz Piña, Juan Rafael Cordero Jiménez

    Published 2012-01-01
    “…<strong></strong>Considering as our main goal to expose the state of the art in diagnosis and treatment of dementia insisting in its latest advances and suggesting practical contributions for its management in our context, we offer a panoramical view of dementia as an important health problem and expose the essentials for its diagnosis and management including cognitive impairment diagnosis, variants, etiologic diagnosis, the diagnosis of demential syndrome, the importance of neuropsychiatric assessment and the treatment options. …”
    Get full text
    Article
  9. 509

    Fatigue in chronic liver disease patients: prevalence, pathophysiology, and management by Artur Kośnik, Maciej Wójcicki

    Published 2022-03-01
    “…In CLD patients, fatigue manifests with both central symptoms, characterised by cognitive impairment, sleep disturbance, apathy, and autonomic dysfunction, and peripheral symptoms, characterised by decreased exercise tolerance and reduced physical activity levels. …”
    Get full text
    Article
  10. 510

    Method of Recognition and Assistance Combining Passive RFID and Electrical Load Analysis That Handles Cognitive Errors by Dany Fortin-Simard, Jean-Sébastien Bilodeau, Sébastien Gaboury, Bruno Bouchard, Abdenour Bouzouane

    Published 2015-10-01
    “…In this paper, we present an affordable system that exploits a combination of passive RFID and the load signatures of appliances to assist elders and to detect errors related to cognitive impairment. The entire multi-sensor system has been implemented and deployed in a real prototype smart home. …”
    Get full text
    Article
  11. 511

    Disability and quality of life in patients with treatment-resistant schizophrenia on long- term clozapine therapy by Dhandapani Nandakumar, Ragul Ganesh, Koushik S. Deb, Raka Jain, Mamta Sood

    Published 2023-06-01
    “…Subgroup analysis revealed significant difference between medication adherence (good vs poor) and cognitive (impairment vs non-impairment) groups. Conclusion: Negative and cognitive symptoms, and medication adherence correlated with disability and QOL.…”
    Get full text
    Article
  12. 512

    Improved spectral clustering algorithm and its application in MCI detection by Jie XIANG, Dong-qin ZHAO

    Published 2015-04-01
    “…In order to detect mild cognitive impairment (MCI) using functional magnetic resonance imaging (fMRI),a method based on fMRI clustering was proposed fMRI data were clustered to obtain the blood oxygen level dependence( BOLD) change model of MCI patients,then abnormal patterns were used to detect disease.The traditional spectral clustering algorithm needs to calculate all of the eigenvalue and eigenvector,so time and space complexity is higher.An improved spectral clustering method was proposed which modified the similar matrix construction method and the setting method of σ and k,and then this method was applied to clustering and detection of MCI patients.To verify the performance of the proposed method,the comparison of the clustering result,classification accuracy using traditional algorithm and Nyström is also done.The comparative experimental results show that the proposed method can get BOLD pattern more accurately,the accuracy of MCI detection is higher than the other two algorithms,and the time and space complexity are less than the traditional algorithm.…”
    Get full text
    Article
  13. 513

    Therapeutic drug monitoring of atypical antipsychotic drugs by Grundmann Milan, Kacirova Ivana, Urinovska Romana

    Published 2014-12-01
    “…Schizophrenia is a severe psychiatric disorder often associated with cognitive impairment and affective, mainly depressive, symptoms. …”
    Get full text
    Article
  14. 514

    Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review by Yasir Rehman, Nadia Rehman, Riaz Rehman

    Published 2014-01-01
    “…The purpose of this literature review is to focus on the systemic inflammation and the role of proinflammatory cytokines IL1, IL6,and TNF and other inflammatory mediators which mediates the cognitive impairment and induces sickness behaviour. Moreover, this review will also help to determine if some patients could have long-term cognitive changes associated with musculoskeletal injuries or as a consequence of surgery and thereby will lead to efforts in reducing that risk.…”
    Get full text
    Article
  15. 515

    Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research by Qi Liu, Chang Liu, Yu Chen, Yumei Zhang

    Published 2022-01-01
    “…The goal of this review is to spread awareness of cognitive impairments in cerebellar disorders.…”
    Get full text
    Article
  16. 516

    Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis by Bruno Lenne, Jean-Luc Blanc, Jean-Louis Nandrino, Philippe Gallois, Patrick Hautecæur, Laurent Pezard

    Published 2013-01-01
    “…The disturbance of cortical communication has been hypothesized as an important factor in the appearance of cognitive impairment in (MS). Cortical communication is quantified here in control subjects and patients with relapsing-remitting multiple sclerosis (RRMS) on the basis of mean coherence in the δ, θ, α, β and γ bands and using mutual information computed between pairs of bipolar EEG signals recorded during resting condition. …”
    Get full text
    Article
  17. 517

    Sex Differences in Parkinson’s Disease: A Narrative Review by Carlo Cattaneo, Javier Pagonabarraga

    Published 2024-12-01
    “…The results confirm the existence of differences between men and women in PD; women have a higher risk of developing disabling motor complications and non-motor fluctuations compared to men, while men have a higher risk of developing cognitive impairment, postural instability, and gait disorders. …”
    Get full text
    Article
  18. 518

    Machine Learning-Based Alzheimer’s Disease Stage Diagnosis Utilizing Blood Gene Expression and Clinical Data: A Comparative Investigation by Manash Sarma, Subarna Chatterjee

    Published 2025-01-01
    “…<b>Background/Objectives:</b> This study presents a comparative analysis of the multistage diagnosis of Alzheimer’s disease (AD), including mild cognitive impairment (MCI), utilizing two distinct types of biomarkers: blood gene expression and clinical biomarker samples. …”
    Get full text
    Article
  19. 519
  20. 520

    Hubungan Antara Tingkat Aktivitas Fisik dengan Fungsi Kognitif pada Usila di Kelurahan Jati Kecamatan Padang Timur by Milfa Sari Muzamil, Afriwardi ., Rose Dinda Martini

    Published 2014-05-01
    “…The prevalence of cognitive impairment is high in the country with high proportion of elderly. …”
    Get full text
    Article