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501
Effects of Gestational Inflammation with Postpartum Enriched Environment on Age-Related Changes in Cognition and Hippocampal Synaptic Plasticity-Related Proteins
Published 2020-01-01“…Increasing evidence indicates that exposure to inflammation during pregnancy intensifies the offspring’s cognitive impairment during aging, which might be correlated with changes in some synaptic plasticity-related proteins. …”
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502
Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease
Published 2025-01-01“…We and other research groups have shown that IN DFO rescues cognitive impairment in several rodent models of Alzheimer Disease (AD).MethodsThis study was designed to probe dosing regimens to inform future clinical trials, while exploring mechanisms within the intracerebroventricular (ICV) streptozotocin (STZ) model.ResultsFive weeks of daily IN dosing of Long Evans rats with 15 μL of a 1% (0.3 mg), but not 0.1% (0.03 mg), solution of DFO rescued cognitive impairment caused by ICV STZ administration as assessed with the Morris Water Maze (MWM) test of spatial memory and learning. …”
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503
Mortality of elder financial and psychological abuse victims in rural Malaysia: a prospective cohort study
Published 2022-07-01“…Individuals with severe cognitive impairment were excluded.Outcome measure Mortality data were provided by the Malaysian National Registration Department and linked to respondents’ national identification numbers. …”
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504
Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study)
Published 2022-07-01“…Common symptoms include fatigue, cognitive impairment and dyspnoea. However, knowledge regarding the nature and risk factors for developing persisting symptoms is still limited. …”
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505
Iron deposition is associated with motor and non-motor network breakdown in parkinsonism
Published 2025-01-01“…Impairment of cerebellar network and language network are associated with motor symptoms and cognitive impairment, respectively. Moreover, dysfunction of the networks is associated with iron deposition in deep nuclei (SN, DN, Putamen).…”
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506
Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation
Published 2019-01-01“…Sepsis-associated encephalopathy (SAE) is a poorly understood condition that leads to long-term cognitive impairment and increased mortality in survivors. …”
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507
Steroid-Responsive Encephalopathy Associated with Thyroiditis (SREAT): A Case Report of Saving a Young Female Life
Published 2023-08-01“…Symptoms include altered mental status, seizures, and cognitive impairment. When diagnostic criteria are met, steroids are the cornerstone of treatment with a reported good response. …”
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508
Updating the Diagnosis and Management of Dementia. Practical Contributions in our Context
Published 2012-01-01“…<strong></strong>Considering as our main goal to expose the state of the art in diagnosis and treatment of dementia insisting in its latest advances and suggesting practical contributions for its management in our context, we offer a panoramical view of dementia as an important health problem and expose the essentials for its diagnosis and management including cognitive impairment diagnosis, variants, etiologic diagnosis, the diagnosis of demential syndrome, the importance of neuropsychiatric assessment and the treatment options. …”
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509
Fatigue in chronic liver disease patients: prevalence, pathophysiology, and management
Published 2022-03-01“…In CLD patients, fatigue manifests with both central symptoms, characterised by cognitive impairment, sleep disturbance, apathy, and autonomic dysfunction, and peripheral symptoms, characterised by decreased exercise tolerance and reduced physical activity levels. …”
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510
Method of Recognition and Assistance Combining Passive RFID and Electrical Load Analysis That Handles Cognitive Errors
Published 2015-10-01“…In this paper, we present an affordable system that exploits a combination of passive RFID and the load signatures of appliances to assist elders and to detect errors related to cognitive impairment. The entire multi-sensor system has been implemented and deployed in a real prototype smart home. …”
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511
Disability and quality of life in patients with treatment-resistant schizophrenia on long- term clozapine therapy
Published 2023-06-01“…Subgroup analysis revealed significant difference between medication adherence (good vs poor) and cognitive (impairment vs non-impairment) groups. Conclusion: Negative and cognitive symptoms, and medication adherence correlated with disability and QOL.…”
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512
Improved spectral clustering algorithm and its application in MCI detection
Published 2015-04-01“…In order to detect mild cognitive impairment (MCI) using functional magnetic resonance imaging (fMRI),a method based on fMRI clustering was proposed fMRI data were clustered to obtain the blood oxygen level dependence( BOLD) change model of MCI patients,then abnormal patterns were used to detect disease.The traditional spectral clustering algorithm needs to calculate all of the eigenvalue and eigenvector,so time and space complexity is higher.An improved spectral clustering method was proposed which modified the similar matrix construction method and the setting method of σ and k,and then this method was applied to clustering and detection of MCI patients.To verify the performance of the proposed method,the comparison of the clustering result,classification accuracy using traditional algorithm and Nyström is also done.The comparative experimental results show that the proposed method can get BOLD pattern more accurately,the accuracy of MCI detection is higher than the other two algorithms,and the time and space complexity are less than the traditional algorithm.…”
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513
Therapeutic drug monitoring of atypical antipsychotic drugs
Published 2014-12-01“…Schizophrenia is a severe psychiatric disorder often associated with cognitive impairment and affective, mainly depressive, symptoms. …”
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514
Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review
Published 2014-01-01“…The purpose of this literature review is to focus on the systemic inflammation and the role of proinflammatory cytokines IL1, IL6,and TNF and other inflammatory mediators which mediates the cognitive impairment and induces sickness behaviour. Moreover, this review will also help to determine if some patients could have long-term cognitive changes associated with musculoskeletal injuries or as a consequence of surgery and thereby will lead to efforts in reducing that risk.…”
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515
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Published 2022-01-01“…The goal of this review is to spread awareness of cognitive impairments in cerebellar disorders.…”
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516
Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis
Published 2013-01-01“…The disturbance of cortical communication has been hypothesized as an important factor in the appearance of cognitive impairment in (MS). Cortical communication is quantified here in control subjects and patients with relapsing-remitting multiple sclerosis (RRMS) on the basis of mean coherence in the δ, θ, α, β and γ bands and using mutual information computed between pairs of bipolar EEG signals recorded during resting condition. …”
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517
Sex Differences in Parkinson’s Disease: A Narrative Review
Published 2024-12-01“…The results confirm the existence of differences between men and women in PD; women have a higher risk of developing disabling motor complications and non-motor fluctuations compared to men, while men have a higher risk of developing cognitive impairment, postural instability, and gait disorders. …”
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518
Machine Learning-Based Alzheimer’s Disease Stage Diagnosis Utilizing Blood Gene Expression and Clinical Data: A Comparative Investigation
Published 2025-01-01“…<b>Background/Objectives:</b> This study presents a comparative analysis of the multistage diagnosis of Alzheimer’s disease (AD), including mild cognitive impairment (MCI), utilizing two distinct types of biomarkers: blood gene expression and clinical biomarker samples. …”
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519
Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation
Published 2024-12-01“…The AANCP inhibited aggregation of Aβ in vitro and alleviated cognitive impairment in a scopolamine-induced in vivo dementia mouse model. …”
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520
Hubungan Antara Tingkat Aktivitas Fisik dengan Fungsi Kognitif pada Usila di Kelurahan Jati Kecamatan Padang Timur
Published 2014-05-01“…The prevalence of cognitive impairment is high in the country with high proportion of elderly. …”
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