The Clock Drawing Task reveals executive dysfunction in the dialysis population – an underrecognized and underestimated problem by Piotr Olejnik, Aleksandra Golenia, Oliwia Maciejewska, Ewa Wojtaszek, Paweł Żebrowski, Jolanta Małyszko

“…Moreover, remarkably similar pattern of clock drawing was observed, with numbers written outside the clock face in the CLOX1 test.Conclusions Executive dysfunctions in dialysis patients may manifest itself before the onset of global cognitive impairment. There appear to be a deficit in the spatial domain as well. …”
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Clinically probable RBD is an early predictor of malignant non-motor Parkinson’s disease phenotypes by Alfonso Enrique Martinez-Nunez, Hunter Hutchinson, Patricia Coutinho, Filipe Pereira Sarmento, Venkat Srikar Lavu, Qingqi Yuan, Jagan Mohan Reddy Dwarampudi, Aysegul Gunduz, Gregory M. Pontone, Michael S. Okun, Joshua K. Wong

“…A survival analysis revealed an association between early RBD and faster progression to cognitive impairment. These NMS profiles may play a critical role in stratifying patients for targeted interventions.…”
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Risk of Venous Thromboembolism in Patients Nursed at Home or in Long-Term Care Residential Facilities by Guido Arpaia, Federico Ambrogi, Maristella Penza, Aladar Bruno Ianes, Alessandra Serras, Patrizia Boracchi, Claudio Cimminiello

“…The risk of DVT for patients with reduced mobility due to cognitive impairment was about half that of patients with cognitive impairment/dementia. …”
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Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion by Zhao-Hui Yao, Xiao-li Yao, Shao-feng Zhang, Ji-chang Hu, Yong Zhang

“…Our findings suggest that TRC may be beneficial in the treatment of cognitive impairment induced by CCH.…”
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Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions by Yu Du, Yufei Song, Xiaojie Zhang, Yan Luo, Wenying Zou, Jiawei Zhang, Jianliang Fu

“…These results suggested that LepR deficiency would protect mice against the CCH-induced cognitive impairment and WMLs by inhibiting glial activation and suppressing proinflammatory responses as well as promoting anti-inflammatory cytokine expression and M2 microglia activation in the white matter.…”
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Pharmacist interventions for older adults with polypharmacy in an ambulatory geriatric clinic by Antonietta Paneccasio, Anna Bondar, Emily Fargo, Marcie Parker, Ardeshir Hashmi, Kenneth Koncilja, Gina Elder

“…Of the 133 additional pharmacist interventions, medication education was the most common (52%).Discussion The results of this study emphasize the benefit of comprehensive medication management with a focus on deprescribing for an older adult population with polypharmacy, the majority of whom had cognitive impairment.…”
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Prenatal Counseling and Diagnosis of COX20 Gene-Related Mitochondrial Complex IV Deficiency: A Case Report and Literature Review by Su J, Zeng L, Chen H, Tong J, Chen Y, Huang L, Deng L, Huang Y

“…Moreover, this report delineated the process of prenatal counseling and diagnostic testing that was undertaken for the subsequent pregnancy of the patient’s mother.Conclusion: The presence of ataxia, cognitive impairment, and peripheral neuropathy in children should prompt consideration of COX20-related mitochondrial disease. …”
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Successful throb endarterectomy in a patient with occlusion of the internal carotid artery by V. V. Akhmetov, K. V. Mozharovskiy, M. S. Gapizov, R. V. Shilov, Yu. V. Chernikova, I. P. Dudanov

“…The results obtained indicate a correlation between the improvement of brain perfusion and cognitive impairment, as well as a positive effect of revascularization of the internal carotid artery on the patient’s quality of life. …”
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White matter hyperintensities and cholinergic degeneration as Lewy body disease by Sungwoo Kang, Seun Jeon, Yeoju Kim, Su‐Hee Jeon, Minsun Choi, Young‐gun Lee, Mijin Yun, Byoung Seok Ye

“…Methods A total of 407 patients with cognitive impairment meeting the diagnostic criteria for AD, DLB, or both (AD+DLB) were assessed. …”
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Evidence-based integration of yoga in psychiatric practice by B. N. Gangadhar

“…Some examples include depression, schizophrenia, anxiety, obsessive–compulsive disorder (OCD), somatoform pain, addiction, mild cognitive impairment, and elderly and childhood disorders. …”
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Knowledge and attitudes towards sarcopenia among healthcare professionals by Jeremy Jun Wei Teng, Raymond Kai Heng Goh, Melanie Mei Ying Tan, Le Alicia How, Li Feng Tan

“…It leads to increased adverse outcomes such as increased risks of falls, fractures, postoperative complications, disability and increased mortality.2 It is associated with many chronic diseases such as heart failure, chronic kidney disease, chronic obstructive pulmonary disease, diabetes and cognitive impairment.2,4 The prevalence of sarcopenia is expected to dramatically increase in the next few decades, especially in ageing populations.6…”
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A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults by Louis Bherer, Kirk I. Erickson, Teresa Liu-Ambrose

“…Results from cross-sectional, longitudinal, and intervention studies with healthy older adults, frail patients, and persons suffering from mild cognitive impairment and dementia are reviewed and discussed. …”
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Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study by Manel Mateu‐Salat, Nicole Stanton‐Yonge, Frederic Sampedro Santaló, José Ignacio Vela, Jesús Díaz Cascajosa, Eva Safont Pérez, Daniela Rego‐Lorca, Ana Chico

“…MPR has been described as a marker of cognitive impairment in people with Type 2 diabetes, but it has never been assessed in people with Type 1 diabetes (T1D). …”
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Association of N-terminal pro-brain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes. by Insa Feinkohl, Naveed Sattar, Paul Welsh, Rebecca M Reynolds, Ian J Deary, Mark W J Strachan, Jackie F Price, Edinburgh Type 2 Diabetes Study-ET2DS Investigators

“…The ventricular N-terminal pro-brain natriuretic peptide (NT-proBNP) is a marker of CHF, suggesting potential as a marker for cognitive impairment and/or depression. This was tested in the Edinburgh Type 2 Diabetes Study (ET2DS).…”
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Operationalizing goal setting as an outcome measure in trials involving patients with frailty, multimorbidity or complexity by Emma Tenison, Katherine Lloyd, Yoav Ben-Shlomo, Emily J. Henderson

“…Disease-specific outcomes have limitations in older people, those with cognitive impairment, multimorbidity, disability or short life expectancy. …”
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Characterization of cognitive functioning in complex PTSD compared to non-complex PTSD by Zoe-Sofia Schöndorf, Zoe-Sofia Schöndorf, Valentin Terhoeven, Anna Jaehn, Daniela Roesch-Ely, Hans-Christoph Friederich, Hans-Christoph Friederich, Christoph Nikendei, David Kindermann, David Kindermann

“…BackgroundPrevious research has indicated cognitive impairments in patients with post-traumatic stress disorder (PTSD), specifically in attention, memory, and executive functioning. …”
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Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach by Alessia Vignoli, Giovanni Bellomo, Federico Paolini Paoletti, Claudio Luchinat, Leonardo Tenori, Lucilla Parnetti

“…Methods This pilot study proposes a serum investigation via nuclear magnetic resonance (NMR) spectroscopy in a consecutive series of AD patients including 57 patients affected by Alzheimer’s disease at dementia stage (AD-dem) and 45 patients with mild cognitive impairment (MCI) due to AD (MCI-AD). As control group, we considered 31 subjects with mild cognitive impairment in whom AD and other neurodegenerative disorders were excluded (MCI). …”
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Postictal Psychosis: Case Report and Literature Review by Joana Regala, João Lourenço, Francisco Moniz-Pereira, António Bento

“…Additionally, she had previous cognitive impairment and encephalomalacia in the right parietooccipital region as a sequela of a moderate-to-severe traumatic brain injury known to precede the emergence of the epilepsy. …”
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Hyponatraemia and hypothyroidism: A case report by Giulia Cantoni, Gabriella Nucera, Pietro Marino

“…An 82-year-old woman arrived at an emergency department with aphasia and a progressive cognitive impairment associated with walking problems during the last week. …”
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The effects of PM2.5 air pollution on human health: A narrative review with a focus on cerebrovascular diseases by Leticia Simo

“…PM2.5 exerts its deleterious effects through complex pathways involving systemic inflammation, oxidative stress, endothelial dysfunction, and neurovascular damage, heightening the risks of ischemic stroke, hemorrhagic stroke, vascular cognitive impairment, and other cerebrovascular disorders. …”
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