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581
Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review
Published 2025-01-01“…Additionally, polyphenols have shown promise in modulating various cellular signaling pathways associated with neuronal viability, synaptic plasticity, and cognitive function. Epidemiological and clinical studies highlight the potential of polyphenol-rich diets to decrease the risk and alleviate symptoms of neurodegenerative disorders and neuroinflammation. …”
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582
Preliminary evidence of immune infiltration and neutrophil degranulation in peripheral blood of non-obese OSA patients related to cognitive decline
Published 2025-01-01“…OSA patients showed a significant decline in overall cognitive function and were associated with higher daytime sleepiness scores. …”
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583
BMAL1 ameliorates type 2 diabetes-induced cognitive impairment via AREG upregulation and PI3K/Akt/GSK-3β pathway activation
Published 2025-01-01“…We identified a marked decrease in BMAL1 levels in the hippocampus of db/db mice, followed by gain- and loss-of-function studies to explore the impact of BMAL1 on cognitive function. Our findings indicated that BMAL1 downregulation led to cognitive deficits, characterized by tau hyperphosphorylation and accumulated amyloid plaque. …”
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584
Relationship between subjective masticatory performance assessed by food acceptance questionnaire and comprehensively assessed oral function in older outpatients at a dental hospit...
Published 2025-01-01“…Age, sex, number of functional teeth, geriatric depression, cognitive function, and oral health-related quality of life were assessed. …”
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585
Electroacupuncture Improves Clearance of Amyloid-β through the Glymphatic System in the SAMP8 Mouse Model of Alzheimer’s Disease
Published 2021-01-01“…After EA treatment, Morris water maze (MWM) test was used to evaluate the cognitive function; HE and Nissl staining was performed to observe the brain histomorphology; ELISA, contrast-enhanced MRI, and immunofluorescence were applied to explore the mechanisms underlying EA effects from Aβ accumulation, glymphatic system function, reactivity of astrocytes, and AQP4 polarization, respectively. …”
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586
Effect of central sensitization on postoperative cognitive dysfunction in total knee arthroplasty patients: a retrospective study
Published 2025-01-01“…Patients were classified into CS (CSI ≥ 40) and non-CS (CSI < 40) groups according to Central Sensitization Inventory (CSI) score. Cognitive function and POCD incidence were assessed with the Mini-Mental State Examination (MMSE), and knee recovery with the Knee Injury and Osteoarthritis Outcome Score (KOOS). …”
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587
Treatment of Vascular Dementia by Using Fuyuan Capsule Combined with "Xingnao Kaiqiao" Acupuncture
Published 2023-06-01“…The change of MMSE score was positively correlated with the change of SOD activity (<italic>r</italic>=0.520, <italic>P</italic>=0.003) and negatively correlated with the expression of TNF-α protein (<italic>r</italic>=-0.308, <italic>P</italic>=0.026).ConclusionFuyuan capsule combined with "Xingnao Kaiqiao" acupuncture could effectively improve the cognitive function of VD patients, improve the symptoms of vascular dementia and improve the ability of daily living activities, which may be related to relieving oxidative stress injury and inhibiting inflammatory response.…”
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588
A comprehensive investigation of Clerodendrum Infortunatum Linn. using LC-QTOF-MS/MS metabolomics as a promising anti-alzheimer candidate
Published 2025-01-01“…The results showed that the extract promoted enhanced cognitive functions in the novel object recognition test. …”
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589
An exploration of distinguishing subjective cognitive decline and mild cognitive impairment based on resting-state prefrontal functional connectivity assessed by functional near-in...
Published 2025-01-01“…PurposeFunctional near-infrared spectroscopy (fNIRS) has shown feasibility in evaluating cognitive function and brain functional connectivity (FC). …”
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590
Feasibility and Preliminary Effects of Acupuncture for Cognitive Dysfunction in Diverse Cancer Survivors: A Pilot, Randomized, Placebo-Controlled Trial
Published 2025-01-01“…Subjective CRCD was assessed by the Functional Assessment of Cancer Therapy-Cognitive Function—Perceived Cognitive Impairment subscale (FACT-Cog PCI) and objective CRCD was assessed by the Hopkins Verbal Learning Test—Revised (HVLT-R). (3) Results: 32 participants (57.1% of eligible patients) were enrolled. …”
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591
Subchronic cyanuric acid treatment impairs spatial flexible behavior in female adolescent rats through depressing GluN2B-dependent neuronal and synaptic function
Published 2025-01-01“…To examine if this exposure induced negative effects on cognitive function in females, we examined the behavioral performance and further attempted to investigate synaptic and neuronal function. …”
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592
Working-memory load decoding model inspired by brain cognition based on cross-frequency coupling
Published 2025-02-01“…Working memory, a fundamental cognitive function of the brain, necessitates the evaluation of cognitive load intensity due to limited cognitive resources. …”
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593
Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review
Published 2025-01-01“…Its ergogenic properties, such as improved strength, endurance, and cognitive function, have been well documented in the literature. …”
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594
2-O-β-D-Glucopyranosyl-L-ascorbic acid, an ascorbic acid derivative isolated from the fruits of Lycium barbarum L., ameliorates high fructose-induced neuroinflammation in mice: inv...
Published 2024-01-01“…Western diet (rich in highly refined sugar and fat) can induce a range of metabolic dysfunctions in animals and humans, including neuroinflammation and cognitive function decline. Neuroinflammation and cognitive impairment, two critical pathological characteristics of Alzheimer’s disease, have been closely associated with microbial alteration via the gut-brain axis. …”
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595
Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of <i>Centella asiatica</i>
Published 2024-12-01“…Urban, family Apiaceae (CAW), improves cognitive function in mouse models of aging and Alzheimer’s disease and affects dendritic arborization, mitochondrial activity, and oxidative stress in mouse primary neurons. …”
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596
Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway
Published 2025-01-01“…Finally, molecular docking studies suggested that RA could directly interact with GRP78, PERK, and IRE1, but not with MANF.Conclusion: RA plays a protective role in improving cognitive function against endotoxemia-associated encephalopathy in mice via inhibiting the GRP78/PERK/MANF pathway.Keywords: Rosmarinic acid, endotoxin, neuronal damage, GRP78/PERK/MANF pathway…”
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597
Meta-narrative review: the impact of music therapy on sleep and future research directions
Published 2025-01-01“…Sleep is essential to human health, yet 27% of the global population suffers from sleep issues, which often lead to fatigue, depression, and impaired cognitive function. While pharmacological treatments exist, non-pharmacological approaches like music therapy have shown promise in enhancing sleep quality. …”
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598
Guidelines for Stroke Critical Rehabilitation
Published 2024-01-01“…Timing of rehabilitation intervention, rehabilitation assessment (history assessment, physical examination, laboratory examination, imaging examination, assessment of conscious state, cognitive function assessment, motor function assessment, swallowing function assessment, ADL function assessment, mental state assessment, respiratory function assessment, diarrhea function assessment, pain assessment, agitation and sedation assessment, cooperation assessment, delirium assessment, nutritional assessment, screening for deep vein thrombosis), rehabilitation goals and plan development; content of rehabilitation intervention The content of rehabilitation intervention (motor function rehabilitation, circulatory function rehabilitation, respiratory function rehabilitation, swallowing function rehabilitation, consciousness disorder rehabilitation, bladder function rehabilitation, rectal function rehabilitation, musculoskeletal joint rehabilitation, skin management, pain and agitation management, deep vein thrombosis management, shoulder subluxation management, nutritional support management), the frequency of rehabilitation interventions, rehabilitation education, the requirements of rehabilitation implementation, the evaluation of the efficacy of rehabilitation, and the indicators of suspension of rehabilitation interventions. intervention pause indicators, rehabilitation efficacy evaluation, referral, follow-up; ⑤rehabilitation implementation conditions: basic conditions, environmental and facility conditions, personnel conditions; ⑥rehabilitation quality control: rehabilitation quality control system, rehabilitation quality assessment system, service feedback mechanism, emergency plan. …”
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599
Feasibility of teleyoga for people with post COVID-19 condition– a mixed method design
Published 2025-01-01“…After 7 weeks of teleyoga there was a significant improvement in cognitive function (p-value = 0.048). No differences were found in the physical tests, health-related quality-of-life, anxiety and depression, sleep or in exercise motivation. …”
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600
Respiratory and Rehabilitation Expert Consensus on Full-cycle Rehabilitation Assessment and Treatment for Elderly Patients with Chronic Obstructive Pulmonary Disease
Published 2024-01-01“…It recommends a comprehensive assessment of elderly COPD patients' multifaceted impairments based on the International Classification of Functioning, Disability, and Health (ICF) framework, covering four aspects:body structure, body function (respiratory function, cardiac function, exercise function, psychological and cognitive function, swallowing function, and nutritional factors), activity and participation, and environmental factors. …”
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