Trait Impulsivity Is Independent of Mild Cognitive Impairment in a Parkinson’s Disease Cohort by Ashani Jeyadevan, Megan C. Bakeberg, Michelle Byrnes, Jade Kenna, Soumya Ghosh, Rick Stell, Sue Walters, Tess Evans, Sarah McGregor, Malcolm Horne, Frank L. Mastaglia, Ryan S. Anderton

“…Based on cognitive scores, participants were divided into two groups, one defined as having mild cognitive impairment (PD-MCI; n = 113) and the other with normal cognitive function (PD-C; n = 189). Trait impulsivity was evaluated using the Barrett Impulsiveness Scale 11 (BIS-11). …”
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Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications by Dariusz Fabian, Klaudia Maria Kufel, Mateusz Teofilak, Natalia Maria Smyl, Olga Śpiołek, Jan Siwiec, Aleksandra Słowikowska, Julia Szatkowska, Marcelina Paula Sztyler-Krąkowska, Agnieszka Alicja Wąsowicz, Franciszek Kędziora

“…The article identifies key neurotrophic factors, such as BDNF (brain-derived neurotrophic factor) and VEGF (vascular endothelial growth factor), which are regulated by physical activity and contribute to improved cognitive function and mental health. The paper demonstrates the multifaceted effects of physical activity on neuroplasticity and brain health. …”
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Effectiveness of a Dyadic Technology–Enhanced Home-Based Horticultural Therapy on Psychosocial Well-Being Among People With Dementia and Their Family Caregivers: Multimethods Pilot... by Patrick Pui Kin Kor, Justina Yat Wa Liu, Arkers Kwan Ching Wong, Alex Pak Lik Tsang, Han Zhi Tan, Daphne Sze Ki Cheung, Humphrey Kwong Wai Leung, Frances Kam Yuet Wong

“…Outcomes were measured at baseline and postintervention (at week 11), including feasibility outcomes, cognitive function, neuropsychiatric symptoms, and happiness levels of people with dementia. …”
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Domain‐Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach by Marlene Tahedl, Ulrich Bogdahn, Bernadette Wimmer, Dennis M. Hedderich, Jan S. Kirschke, Claus Zimmer, Benedikt Wiestler

“…Finding: No associations were found for cognitive function. The extremity‐specific MAP predicted extremity‐specific motor progression over 1 and 3 years above chance level. …”
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Thyroid function abnormalities in individuals with sickle cell disease: a meta-analysis by Sagad O. O. Mohamed, Hussein Ahmed, Mohammed A. H. Mohammednoor, Khalefa B. K. Alzubeir, Safaa Fadlelmoula, Osman O. A. Abdallah, Izzut Awad Ahmed

“…Thyroid disorders can have significant clinical consequences, including growth retardation and impaired cognitive function. However, there is a disparity in the available data concerning the magnitude and spectrum of thyroid abnormalities in this population. …”
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Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT by Kristen L. Nowak, Anna Ostrow, Ester S. Oh, Zhiying You, Michel Chonchol

“…These results suggest that cognitive function should be monitored following AKI in this patient population.…”
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A synergistic effect of secondhand smoke with vitamin D deficiency on cognitive impairment in older adults: a cross sectional study by Yan Li, Qianqian Shen, Chengyu Chen, Xueru Yin, Xinru Wang, Xiyue Yang, Xueqian Zhang, Lei Chen, Jian Xu, Guifang Gong

“…ObjectivesTo investigate whether exposure to secondhand smoke (SHS) aggravates the detrimental effect of vitamin D deficiency (VDD) on cognitive performance in the elderly.MethodsBased on National Health and Nutrition Examination Surveys (NHANES) 2011–2014, 1,446 non-smoking participants (≥ 60 years old) with detailed serum 25-hydroxyvitamin D [25(OH)D], concentration of cotinine and tests score of cognitive function were included. Cognitive impairment was defined as having a cognitive score in the lowest quartile. …”
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No Relation Between Cognitive Impairment, Physical Disability and Serum Biomarkers in a Cohort of Progressive Multiple Sclerosis Patients by Bartosz Gajewski, Iwona Karlińska, Małgorzata Domowicz, Igor Bednarski, Mariola Świderek-Matysiak, Mariusz Stasiołek

“…The aim of this prospective study in a group of people with progressive MS was to determine whether changes in the levels of selected serum biomarkers and in cognitive function may predict disease progression, and therefore refine the decision-making process in the evaluation of MS patients. …”
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Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions by Chi-Hang Yee, Ching Leung, Yuki Yu-Ting Wong, Sylvia Lee, Jenny Li, Pauline Kwan, Winnie Chiu-Wing Chu, Vincent Chung-Tong Mok, Chi-Fai Ng

“…We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function. Methods. A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment. …”
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Sleep patterns and long-term mortality among older Israeli adults: a population-based study by Lital Keinan-Boker, Yariv Gerber, Saar Ashri, Gali Cohen, Tal Hasin

“…We explored sleep patterns and long-term mortality in older adults and tested whether the relationship is modified by cognitive function.Methods We analysed data from 1519 participants in the National Health and Nutrition Survey of older adults aged 65+ years (‘Mabat Zahav’), conducted by the Israel Center for Disease Control during 2005–2006. …”
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Effectiveness of mental health interventions for older adults in South Asia: A scoping review. by Hoimonty Mazumder, Farah Faizah, Easter Protiva Gain, Irfath Sharmin Eva, Kaniz Ferdouse Mou, Nobonita Saha, Farzana Rahman, Jyoti Das, A M Khairul Islam, Fazilatun Nesa, M Mahbub Hossain

“…Depression and anxiety were the most frequent mental health outcomes, followed by quality of life, cognitive function, self-esteem, physical performance, and many more.…”
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Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes by Lin Sun, Xue Diao, Xiaokun Gang, You Lv, Xue Zhao, Shuo Yang, Ying Gao, Guixia Wang

“…Chinese T2DM patients (n=120) aged 50–70 years were divided into groups with impaired (mild, moderate, and severe) and normal cognitive function based on Montreal Cognitive Assessment and Mini-Mental State Examination scores. …”
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Effect of endoscopic sinus surgery on eustachian tube function in adult patients with chronic rhinosinusitis by Mahmoud Atef Abdelghaffar Youssef, Nassim Talaat Nassim, MohamedNourEddin Bashir Alkeeb, Tareq Muhammad Algarf

“…Abstract Background Chronic rhinosinusitis (CRS) is a frequent chronic heterogeneous inflammatory disease of the upper airways and paranasal sinuses persistent for ≥ 12 weeks causing considerable healthcare expenses and reduction of patients’ quality of life due to severe tiredness and disappointment as well as diminished cognitive function. CRS is commonly associated with eustachian tube (ET) dysfunction. …”
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The role of CXCL12/CXCR4/CXCR7 axis in cognitive impairment associated with neurodegenerative diseases by Rojin Sarallah, Shima Jahani, Alireza Soltani Khaboushan, Amir Kian Moaveni, Maryam Amiri, Masoumeh Majidi Zolbin

“…PD studies reveal that CXCL12/CXCR4 signaling influences dopaminergic neuron survival and microglial activation, affecting cognitive function. In MS, the axis modulates neuroinflammation and demyelination processes, impacting cognitive performance. …”
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Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model... by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…Although there was no significant difference in cognitive function between the hUC-MSC groups, NEP-enhanced hUC-MSCs had superior neurogenesis and anti-inflammation properties compared to naïve hUC-MSCs due to increased NEP in the hippocampus by enriched NEP-possessing EVs. …”
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Constant Dizziness Versus Episodic Vertigo in Ménière’s Disease: Health-Related Quality of Life, Cognitive Dissonance, and Postural Problems by Ilmari Pyykkö, Jing Zou, Vinaya Manchaiah

“…Conclusion: We emphasize that constant dizziness in MD constitutes a long-term maladaptation to a vestibular and visual cognitive function causing cognitive dissonance. Different types of vertigo and their associated complaints require different treatment strategies to the manage balance problems and to cope with the disease, but best practices is still under research.…”
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The long-term outcome of children with VP shunt and hydrocephalus: motor developmental outcome and QOL of patients with hydrocephalus is associated with the number of revisional pr... by Danielle S. Wendling-Keim, Hannah Luz, Elena Kren, Oliver Muensterer, Markus Lehner

“…Therefore, we performed a study including a questionnaire, which aimed to analyze parameters that may have an impact on the cognitive function and quality of life of the pediatric patient with hydrocephalus.MethodsIn this retrospective study, we included 81 patients aged 0–17 with hydrocephalus who were treated with a ventriculo-peritoneal shunt at a single institution. …”
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Unlocking the full potential of resistance training: a comparative analysis of low- and high-intensity effects on neurotrophic growth factors and homocysteine by Chongwen Zuo, Yi Yin, Zhiyang Zheng, Ren Mu, Yuxin Liang, Shan Wang, Chaoqun Ye

“…Abstract Objective Resistance training has been demonstrated an effective approach for preventing the cognitive function decline through physiological mechanisms; however, the effect of acute resistance training at different intensities on growth factor and homocysteine levels remains unclear. …”
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Do... by Yang M, Zhou L, Long G, Liu X, Ouyang W, Xie C, He X

“…Intranasal insulin has shown significant benefits in improving glucose metabolism, insulin sensitivity and cognitive function. However, its impact on postoperative delirium and insulin sensitivity biomarkers remains unknown.Aim: This randomized, double-blind, placebo-controlled trial was to evaluate whether intranasal insulin reduces the incidence and severity of postoperative delirium (POD) in older patients undergoing joint replacement, and its effect on insulin sensitivity-related biomarkers.Methods: 212 older patients (≥ 65 years) were randomly assigned to receive either 40 IU of intranasal insulin (n=106) or a placebo (n=106) for 8 days. …”
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Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice by Josh Houlton, Lisa Y. Y. Zhou, Deanna Barwick, Emma K. Gowing, Andrew N. Clarkson

“…Our findings support age-related differences in recovery of cognitive function after stroke. Interestingly, aged stroke animals outperformed their sham counterparts, suggesting reopening of a critical window for recovery that is being mediated by BDNF.…”
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