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161
Biological sex, microglial signaling pathways, and radiation exposure shape cortical proteomic profiles and behavior in mice
Published 2025-02-01“…Patients receiving cranial radiation therapy experience tissue damage and cognitive deficits that severely decrease their quality of life. …”
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162
Developmental dysfunction in a preclinical model of Kcnq2 developmental and epileptic encephalopathy
Published 2025-02-01“…Background: Developmental and epileptic encephalopathies (DEE) are rare but severe neurodevelopmental disorders characterised by early-onset seizures often combined with developmental delay, behavioural and cognitive deficits. Treatment for DEEs is currently limited to seizure control and provides no benefits to the patients' developmental and cognitive outcomes. …”
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163
Repeated social defeat in male mice induced unique RNA profiles in projection neurons from the amygdala to the hippocampus
Published 2025-02-01“…Collectively, there were unique RNA profiles of stress-influenced projection neurons and these profiles were associated with hippocampal-dependent behavioral and cognitive deficits.…”
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164
Results of Cultural Adaptation of Cognitive Stimulation Therapy (CST) for Elderly and Old Age People with Cognitive Impairment in Russia
Published 2024-11-01“…Results of surveys and observations received during the pilot study regarding feedback from program participants, staff of a residential facility for elderly patients with cognitive deficits, and group leaders were analyzed. <strong>Conclusions.…”
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165
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
Published 2025-02-01“…However, despite the high numbers of affected individuals presenting to clinical services with cognitive impairment, little work has been undertaken to date on the suitability of current memory clinic tests for identifying the cognitive deficits in this new acquired cognitive disorder.The aim of this study was therefore to determine the performance of people with post-Covid syndrome presenting with cognitive impairment on the Addenbrooke's Cognitive Examination-III (ACE-III), a cognitive test used widely in memory clinics. …”
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166
Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology
Published 2025-02-01“…DSS serum can increase the cell viability of HT-22 and reduce apoptosis mainly by alleviating mitochondrial calcium overloading.Conclusion: DSS can modulate the calcium signaling pathway and enhance the cAMP/PKA/CREB signaling pathway to ameliorate Tau aberrant phosphorylation, cognitive deficits and neuronal apoptosis after AD. Keywords: Alzheimer’s disease, calcium signaling pathway, cAMP/PKA/CREB signaling pathway, Danggui-Shaoyao-San, apoptosis, serum pharmacology…”
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167
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…Abstract Background: Melatonin (MLT) can improve mitophagy, thereby ameliorating cognitive deficits in Alzheimer’s disease (AD) patients. …”
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168
Disorders of the central nervous system cognitive and mnestic functions in genetic arterial hypertension and with the use of beta-blockers of different generations
Published 2024-09-01“…Drug correction of arterial hypertension with hypertril (a β-blocker of the latest generation with NO-mimetic action) has a highly effective effect on the development of conditioned-reflex skills and the ability to learn that indicates a reduction in cognitive deficits in SHR with essential arterial hypertension.…”
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169
Altered regional brain activity and functional connectivity in relation to blood lead levels
Published 2025-01-01“…Conclusions The disruption in insula coordination may significantly impair long-range FC and contribute to cognitive deficits resulting from lead exposure. The insula appears to be a pivotal region in lead-associated neurocognitive impairment.…”
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170
Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy
Published 2025-01-01“…The significant cognitive deficits we observed among females carrying the APOE ε4 allele highlight previously unexplored genetic and sex-related influences on cognition. …”
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171
Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation
Published 2023-08-01“…Karcher, and Deanna M. Barch, "Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective," Neuropsychology Review 28, no. 4 (2018): 509, https://doi.org/10.1007/s11065-018-9388-2…”
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