LiveDrive AI: A Pilot Study of a Machine Learning-Powered Diagnostic System for Real-Time, Non-Invasive Detection of Mild Cognitive Impairment by Firas Al-Hindawi, Peter Serhan, Yonas E. Geda, Francis Tsow, Teresa Wu, Erica Forzani

“…Key findings demonstrate the feasibility of using nuanced driving features, such as velocity and acceleration during turning, as indicators of cognitive decline. This approach holds promise for integration into smartphone or car applications, enabling real-time, continuous cognitive health monitoring. …”
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Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study by Chunhui Zhou, Ganfeng Yang, Marc Theeboom, Hua Yang, Ruiting Zhu, Zijian Zhou, Dong Zhu

“…Early interventions targeting visual impairments may help mitigate cognitive decline and improve the quality of life for these patients.…”
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Clinical characteristics, etiology, and treatment of young adult‐onset epilepsy: A 24‐year retrospective study by Xu Zhang, Feng Xiang, Ziyu Wang, Yang Li, Chenjing Shao, Xiaoyang Lan, Senyang Lang, Xiangqing Wang

“…However, these two causes did not necessarily result in prompt medication or poor epilepsy control. Co‐morbid cognitive decline was more prevalent than headache and anxiety/depression. …”
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The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study by Daniel Woo, Richard Thompson, Carl D Langefeld, Nichol McBee, Daniel Hanley, Matthew L Flaherty, Lauren Sansing, Karen Lane, Lee A Gilkerson, Achala Vagal, Nathan Walborn, Wendy Ziai, Noeleen Ostapkovich, Kevin Triene, Timothy David Howard

“…Background The REpeated ASSEssment of SurvivorS (REASSESS) study will conduct long-term cognitive, functional and neuropsychiatric performance assessments to determine whether evacuation of spontaneous intracerebral haemorrhage (ICH) reduces the risk of later cognitive decline in the ageing brain.Methods and analysis This study will compare rates of cognitive decline under two treatment strategies for ICH. …”
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Sex Modified the Association between Sleep Duration and worse Cognitive Performance in Chinese Hypertensive Population: Insight from the China H-Type Hypertension Registry Study by Xinlei Zhou, Junpei Li, Chao Yu, Wangsheng Fang, Yanyou Xie, Li Wang, Si Shen, Wei Zhou, Lingjuan Zhu, Tao Wang, Xiao Huang, Huihui Bao, Jianglong Tu, Xiaoshu Cheng

“…Objectives. Cognitive decline could be seen as the sign of preclinical phase of dementia, which was found to be sex differentiated. …”
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Amygdala Nuclei Atrophy in Cognitive Impairment and Dementia: Insights from High-Resolution Magnetic Resonance Imaging by Evija Peiseniece, Nauris Zdanovskis, Kristīne Šneidere, Andrejs Kostiks, Guntis Karelis, Ardis Platkājis, Ainārs Stepens

“…The amygdala, a key structure in emotional processing and memory, may play a pivotal role in detecting cognitive decline. This study examines differences in amygdala nuclei volumes in patients with varying levels of cognitive performance to evaluate its potential as a biomarker. …”
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Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment by Congcong Fang, Longqin Lv, Shanping Mao, Huimin Dong, Baohui Liu

“…In our review, we focus on a description of cognitive decline in PD, expound emphatically the pathological mechanisms underlying cognition deficits in PD, then give a comprehensive overview of specific therapeutic strategies, and finally dissect what fresh insights may bring new exciting prospect for the subfield.…”
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Influence of Hypertension on Neurocognitive Domains in Nondemented Parkinson’s Disease Patients by Jacob D. Jones, Charles Jacobson, Martina Murphy, Catherine Price, Michael S. Okun, Dawn Bowers

“…Health comorbidities, particularly cardiovascular risk factors, are well known to pose risks for cognitive decline in older adults. To date, little attention has focused on the impact of these comorbidities on Parkinson’s disease (PD). …”
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Causal Effects of PM2.5, NOx, and NO2 on Cognitive Function: A Two-sample Mendelian Randomization Study by Yilin Tang, Zhenyu Li, Yicheng Fu, Mingyi Zhao

“…Abstract Epidemiological studies have revealed that air pollutants are related to cognitive decline, but a causal relationship has not been established. …”
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Enhanced detection of mild cognitive impairment in Alzheimer’s disease: a hybrid model integrating dual biomarkers and advanced machine learning by John Sahaya Rani Alex, R. Roshini, G. Maneesha, Jeetashree Aparajeeta, B. Priyadarshini, Chih-Yang Lin, Chi-Wen Lung

“…Abstract Alzheimer's disease (AD) is a complex, progressive, and irreversible neurodegenerative disorder marked by cognitive decline and memory loss. Early diagnosis is the most effective strategy to slow the disease's progression. …”
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Impaired network organization in mild age‐related hearing loss by Zhaopeng Tong, Chunhua Xing, Xiaomin Xu, Jin‐Jing Xu, Yuanqing Wu, Richard Salvi, Xindao Yin, Fei Zhao, Yu‐Chen Chen, Yuexin Cai

“…The prolonged loss of sensory information associated with ARHL‐induced compensatory within‐network segregations and between‐network integrations in the DMN might reduce network information processing and accelerate brain aging and cognitive decline.…”
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Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice by Zhe-Zhe Zhang, Li-Ping Zeng, Jing Chen, Yong-Fang Wu, Ya-Tao Wang, Lan Xia, Qi-Gang Yang, Fang Wang, Gui-Hai Chen

“…However, little is known about the specific impact of adolescent environmental enrichment (EE) on age-associated cognitive decline and the changes in synaptic proteins caused by prenatal inflammation. …”
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A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults by Louis Bherer, Kirk I. Erickson, Teresa Liu-Ambrose

“…Together these finding suggest that physical exercise is a promising nonpharmaceutical intervention to prevent age-related cognitive decline and neurodegenerative diseases.…”
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Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data by Meghan B. Mitchell, Cynthia R. Cimino, Andreana Benitez, Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Steven D. Shirk, Alireza Atri, Annie Robitaille, Stuart W. S. MacDonald, Magnus Lindwall, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin

“…Engagement in cognitively stimulating activities has been considered to maintain or strengthen cognitive skills, thereby minimizing age-related cognitive decline. While the idea that there may be a modifiable behavior that could lower risk for cognitive decline is appealing and potentially empowering for older adults, research findings have not consistently supported the beneficial effects of engaging in cognitively stimulating tasks. …”
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A prospective study on association between comprehensive lifestyle scores and cognitive function changes in community-dwelling older adults in Tianjin city by Muya ZHANG, Xian CAI, Liping ZU, Huichao ZHAO, Tianyu WANG, Chenyu LI, Jing YUAN, Fei MA

“…Adhering to a healthy lifestyle may reduce the risk of cognitive decline.…”
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Persistent depressive symptom trajectory is associated with cognitive impairment: a population-based longitudinal study of aging in Taiwan by Hsiao-Chen Lin, Wai-Lam Lao, Te-Chia Tseng, Chih-Jung Yeh

“…Only persistent depressive symptom trajectory reached statistical significance in all three models. Cognitive decline was evident across all trajectories. …”
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Systematic identification and quantification of factors and their interactions with age, sex, and panel wave influencing cognitive function in Korean older adults by Eunmi Kim, Eunmi Kim, Jinkyung Oh, Jinkyung Oh, Jungsoo Gim, Jungsoo Gim, Jungsoo Gim, Iksoo Huh, Iksoo Huh

“…BackgroundCognitive decline in older adults is influenced by diverse factors, and degrees of influence of these factors may vary depending on sex, age cohorts, and passage of time. …”
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Large-Scale Neuronal Network Dysfunction in Diabetic Retinopathy by Xin Huang, Yan Tong, Chen-Xing Qi, Han-Dong Dan, Qin-Qin Deng, Yin Shen

“…Our results offer important insights into the neural mechanisms of visual loss and cognitive decline in DR patients.…”
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Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review by Tingting Wang, Xin Huang, Shujun Sun, Yafeng Wang, Linlin Han, Tao Zhang, Tianhao Zhang, Xiangdong Chen

“…Postoperative neurocognitive dysfunction (PND) is a prevalent and debilitating complication in elderly surgical patients, characterized by persistent cognitive decline that negatively affects recovery and quality of life. …”
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Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives by Tinne Vandenbroeke, Ellen Andries, Marc J.W. Lammers, Anouk Hofkens-Van den Brandt, Griet Mertens, Vincent Van Rompaey

“…Objectives: Hearing loss is associated with increased cognitive decline and incident dementia in older adults. …”
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