The trajectory of changes in cognitive frailty and factors influencing it in elderly patients with cerebral infarction by Shengnan Xu, Qin Liang, Li Zhang, Shihua Liu

“…[Objective] The trajectory of cognitive frailty in elderly patients with cerebral infarction was analyzed, and the influencing factors were discussed. [ Methods] A total of 100 elderly patients with cerebral infarction hospitalized in Suzhou Hospital of Anhui Medical University from January to September in 2023 were selected for the study.Clinical data were collected on the patients, and cognitive frailty was assessed using the Frailty Screening Scale and the Montreal Cognitive Assessment Questionnaire (MoCA) at the time of admission and 1, 3, 6 months after treatment.Failty score ≥3 scores and MoCA <26 scores were defined as cognitive fraily.Potential categories of cognitive frailty change trajectories were identified by latent category growth modeling, and multifactorial logistic regression analyzed the factors influencing patients' cognitive frailty change trajectories. [ Results] The trajectory of cognitive frailty change in elderly patients with cerebral infarction identified by model fitting can be categorized into a group with a persistently low level of frailty (30 cases), a group with a slow rise in frailty (52 cases), and a group with a persistently high level of frailty (18 cases).Multifactorial logistic regression analysis showed that older age, poor sleep quality, and the number of comorbid chronic diseases > 4 were all risk factors for the development of persistent low levels of cognitive frailty into a slow rise in cognitive decline in elderly patients with cerebral infarction (P<0.05), Higher body mass index and high self-care ability were both protective factors for the development of persistent low levels of cognitive decline into a slow rise in cognitive decline in elderly patients with cerebral infarction (P<0.05).Older age, poor sleep quality and the number of comorbid chronic diseases >4 were risk factors for the progression of persistent low levels of cognitive decline to persistent high levels of cognitive decline in elderly patients with cerebral infarction (P < 0.05), and higher self-care ability were protective factors for the progression of persistent low levels of cognitive decline to persistent high levels of cognitive decline in elderly patients with cerebral infarction (P < 0.05). …”
Get full text

Occurrence of severe cognitive impairment in elderly individuals with poor glycemic control Vs elderly individuals with good glycemic control or no DM: a case control study” by Basma Salman, Fatima Jehangir, Aroosa Jahan, Saira Aslam, Nadra Ansari

“… ABSTRACT: Background: There is substantiatial corroboration that diabetes (both T1DM and T2DM) plays an essential role in predisposition to cognitive decline thus leading to dementia in both human and animal studies. (1,2,3). …”
Get full text

Atrial fibrillation and cognitive impairment: mechanisms, influencing factors, and prospects by Li-Juan Huang, Jian-Shu Chen, Yu-Zhe Song, Peng Chang

“…IntroductionAtrial fibrillation (AF) is a prevalent cardiac arrhythmia and a significant contributor to cardioembolic stroke, a condition closely linked to cognitive decline. However, research reveals that AF itself is independently associated with an increased risk of cognitive impairment. …”
Get full text

Cognitive Impairment in Genetic Parkinson’s Disease by A. Planas-Ballvé, D. Vilas

“…Monogenic forms of genetic PD show distinct cognitive profiles and rate of cognitive decline progression. Cognitive impairment is higher in GBA- and SNCA-associated PD, lower in Parkin- and PINK1-PD, and possibly milder in LRRK2-PD. …”
Get full text

Nonconvulsive Status Epilepticus on Electroencephalography: An Atypical Presentation of Subacute Sclerosing Panencephalitis in Two Children by Pratibha Singhi, Arushi Gahlot Saini, Jitendra Kumar Sahu

“…Subacute sclerosing panencephalitis is a neurodegenerative disease secondary to measles infection that usually has a typical presentation with progressive myoclonia, cognitive decline, and periodic slow-wave complexes on electroencephalography. …”
Get full text

Dietary Fatty Acids and Predementia Syndromes by Vincenzo Solfrizzi, Vincenza Frisardi, Cristiano Capurso, Alessia D' Introno, Anna M. Colacicco, Gianluigi Vendemiale, Antonio Capurso, Francesco Panza

“…An increasing body of epidemiological evidence suggests that elevated saturated fatty acids (SFA) could have negative effects on age-related cognitive decline (ARCD). Furthermore, a reduction of risk for cognitive decline and mild cognitive impairment (MCI) has been found in population samples with elevated fish consumption, and high intake of monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), particularly n-3 PUFA. …”
Get full text

Effect of Combined Antihypertensive and Lipid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? by Ze-Min Kuang

“…Risk factors for cardiovascular disease such as hypertension and hyperlipidemia are associated with cognitive decline. However, there is still no clear evidence that the use of antihypertensive or lipid-lowering therapy can prevent or delay cognitive decline or development of dementia. …”
Get full text

Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? by Irena Martinić-Popović, Arijana Lovrenčić-Huzjan, Vida Demarin

“…Advanced carotid disease is known to be associated with symptomatic cerebrovascular diseases, such as stroke or transient ischemic attack (TIA), as well as with poststroke cognitive impairment. However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evident stroke or TIA, so it is also suspected to be an independent risk factor for dementia. …”
Get full text

Successful Aging and Longevity in Older Old Women: The Role of Depression and Cognition by Daniel Paulson, Mary Elizabeth Bowen, Peter A. Lichtenberg

“…Based in successful aging theory and terminal cognitive drop research, this paper investigates cerebrovascular burden (CVB), depressive symptoms, and cognitive decline as threats to longevity. A subsample of stroke-free women over the age of 80 was identified in the Health and Retirement Survey (years 2000–2008). …”
Get full text

Remembering what did not happen: the role of hypnosis in memory recall and false memories formation by Donato Giuseppe Leo, Donato Giuseppe Leo, Davide Bruno, Riccardo Proietti, Riccardo Proietti

“…Additionally, cardiovascular diseases may lead to cognitive decline and memory loss, also increasing the occurrence of false events recall. …”
Get full text

Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…We investigated the relationship between urinary Alzheimer-associated neuronal thread protein (AD7c-NTP) levels and apolipoprotein epsilon 4 (ApoE ɛ4) alleles, as well as other factors that cause cognitive decline, in the cognitively normal population. …”
Get full text

The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review by Julia Lachowska, Karolina Senior, Jerzy Smandek, Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński

“…Both RET and aerobic exercise have been shown to delay the onset of cognitive decline, with RET also reducing amyloid plaque formation and promoting neuroprotection. …”
Get full text

Relationships between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults: A study based on the China health and retirement longitudinal... by Yixuan Ma, Xinze Wu, Yinjiao Zhao, Weihao Hong, Yisheng Luan, Peiyu Song, Bing Zhang

“…Objective: As the population ages, concerns about cognitive decline have become increasingly relevant in medical consultations. …”
Get full text

The intricate interplay between dietary habits and cognitive function: insights from the gut-brain axis by Ruyi Zhang, Ruyi Zhang, Meiya Zhang, Pengyu Wang

“…The Mediterranean diet has been associated with improved cognitive performance and a delay in cognitive decline in elderly populations. However, challenges in dietary intervention implementation, including adherence and individual variability, remain. …”
Get full text

Revealing the Role of Social Support on Cognitive Deficits in Fibromyalgia Syndrome by Carmen M. Galvez-Sánchez, Gustavo A. Reyes del Paso, Casandra I. Montoro

“…Despite the relevance of cognitive deficits in fibromyalgia syndrome (FMS) and the attempts to elucidate the influence of the disorder symptoms in the cognitive decline reported by patients, no studies have explored the specific role of social support on cognition in FMS. …”
Get full text

Mapping and modeling age-related changes in intrinsic neural timescales by Kaichao Wu, Leonardo L. Gollo

“…Aging, often associated with cognitive decline, involves progressive neuronal and synaptic loss, reshaping brain structure and dynamics. …”
Get full text

Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease by Meng Ying Cui, Yang Lin, Ji Yao Sheng, Xuewen Zhang, Ran Ji Cui

“…However, in most cases, drug therapy is accompanied with clinical delays when older adults have suffered from cognitive decline in episodic memory, working memory, and executive function. …”
Get full text

Fighting Alzheimer’s with Movement: The Role of Physical Activity in Disease Management by Agnieszka Kosińska, Magdalena Balwierz, Karolina Kalinowska, Urszula Świrk, Jan Karczmarz, Joanna Orzechowska, Marika Gutowska, Michał Orzechowski, Aleksandra Paprocka, Paulina Fijałek

“…It reviews existing research to explore how exercise affects cognitive decline, identifies mechanisms through which physical activity may slow disease progression, and evaluates practical recommendations for integrating exercise into Alzheimer's management. …”
Get full text

Neural Plastic Effects of Cognitive Training on Aging Brain by Natalie T. Y. Leung, Helena M. K. Tam, Leung W. Chu, Timothy C. Y. Kwok, Felix Chan, Linda C. W. Lam, Jean Woo, Tatia M. C. Lee

“…This implies that cognitive training can possibly ameliorate age-associated cognitive decline by inducing training-specific neural plastic changes at both neural and behavioral levels. …”
Get full text

The Relationship between Removable Dental Prostheses and Brain Activity in Elderly Individuals: Systematic Review by Arpit Sikri, Jyotsana Sikri, Rinshul Saroch, Charanjeet Singh Gill, Rimple Gupta, Chetan Pathak

“…Findings indicate a positive association between the use of removable dental prostheses and improved cognitive function, with potential therapeutic implications for managing cognitive decline. Conclusion: Removable dental prostheses play a crucial role in enhancing neurological health and preventing cognitive decline, making them an important consideration in the management of neurodegenerative diseases.…”
Get full text