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4681
Frameworks for the design and reporting of anaesthesia interventions in perioperative clinical trials
Published 2025-03-01“…Methods: This study comprised three phases: (1) initial framework development—text describing the delivery of anaesthetic interventions was coded and categorised into components using thematic analysis; (2) refinement of frameworks—facilitated structured group discussions were conducted with perioperative clinicians, researchers, and journal editors to elicit additional framework categories and consider clarity and feasibility; (3) framework testing and further refinement—cognitive interviews with professionals undertaking trials evaluating anaesthesia interventions to test the feasibility of using the frameworks in contemporary perioperative trials. …”
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4682
Adherence and efficacy outcomes in young Australians with suicidal ideation using a self-management app and digital engagement strategy compared with a sham app: a three-arm random...
Published 2025-01-01“…They were randomly assigned 1:1:1 to receive (i) LifeBuoy-an app which delivered third wave cognitive behavioural therapy (CBT) skills, (ii) the LifeBuoy app plus a digital engagement strategy, or (iii) a sham app to minimise expectancy bias. …”
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4683
Evaluation of Machine Learning Algorithms for Classification of Visual Stimulation-Induced EEG Signals in 2D and 3D VR Videos
Published 2025-01-01“…By analyzing EEG signals, researchers can explore the neural mechanisms underlying cognitive and emotional responses to VR stimuli. However, distinguishing EEG signals recorded by two-dimensional (2D) versus three-dimensional (3D) VR environments remains underexplored. …”
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4684
Interleukin IL1a and IL6 gene polymorphism: search for association with APOE genotype and clinical course of sporadic Alzheimer’s disease
Published 2019-09-01“…The study included 110 patients with sporadic AD and 115 age-and-gender-matched healthy controls (HC) without cognitive decline (Lithuanian population). Genotyping of IL1A -889C>T (rs1800587) and IL6 -174G>C (rs1800795, Intron type) was performed using real-time PCR (RT-PCR). …”
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4685
Different cortex activation between young and middle-aged people during different type problem-solving: An EEG&fNIRS study
Published 2025-03-01“…Finally, the EEG and fNIRS correlation results showed positive correlations between HbO and alpha frequency band power in specific brain regions while solving general knowledge questions, particularly in the middle-aged group.The study reveals age-related differences in behavioral performance, brain activation patterns, and neural correlates during various cognitive tasks, showcasing distinct strengths between middle-aged and young individuals in specific question types.…”
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4686
Web-based interventions for fear of cancer recurrence: A scoping review with a focus on suggestions for the development and evaluation of future interventions.
Published 2024-01-01“…The most common theoretical framework for interventions is cognitive behavioural therapy (CBT), followed by mindfulness-based and mixed CBT, mindfulness, acceptance and commitment therapy (ACT), relaxation approaches. …”
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4687
Healthcare trajectories of aging individuals during their last year of life: application of process mining methods to administrative health databases
Published 2025-02-01“…Stratifying according to the cause of death highlighted that LTC accommodation was preponderant for individuals who died of physical and cognitive frailty. Conversely, services offered by local community centers were more prevalent among individuals who died of a terminal illness. …”
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4688
Targeted Transition Readiness Workshops for Pediatric Brain Tumor Survivors: Feasibility, Acceptability, and Preliminary Effects
Published 2025-01-01“…The program consisted of three hybrid workshops that targeted disease-related self-management skills, social skills, and cognitive functioning, as well as parallel workshops for their caregivers. …”
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4689
Learning how to swim in 5- to 12-year-old children: a scoping review of evidence-based motor learning methods
Published 2025-02-01“…., young, competitive swimmers or children with disabilities), or cognitive/motivational outcomes were excluded. Review selection and characterization were performed by three independent reviewers using pretested forms.ResultsA total of 23 studies were included, which were classified into three main categories: traditional motor learning methods (n = 4), contemporary methods (n = 1), and atheoretical methods (n = 18). …”
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4690
Neurodevelopmental outcomes of very low birth weight preterm infants during the COVID-19 pandemic
Published 2025-03-01“…No significant differences were observed in the composite cognitive, language, and motor scores between two groups. …”
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4691
Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer’s Disease
Published 2016-01-01“…Gender-specific central dysrhythmia and network alterations in APPswePS1dE9 point to a functional role in behavioral and cognitive deficits and might serve as early biomarkers for AD in the future.…”
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4692
Identifying neurobiological heterogeneity in clinical high-risk psychosis: a data-driven biotyping approach using resting-state functional connectivity
Published 2025-02-01“…Functional connectivity (FC) features that were correlated with symptom severity were subjected to the single-cell interpretation through multikernel learning (SIMLR) algorithm in order to identify latent homogeneous subgroups. The cognitive function, clinical symptoms, FC patterns, and correlation with neurotransmitter systems of biotype profiles were compared. …”
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4693
The regulatory role of cystatin C in autophagy and neurodegeneration
Published 2019-07-01“…In Parkinson’s disease, serum cystatin C levels can predict disease severity and cognitive dysfunction, although the exact involvement of cystatin C remains unclear. …”
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4694
Cannabinoid type-1 receptors in CaMKII neurons drive impulsivity in pathological eating behavior
Published 2025-02-01“…Importantly, other contingent behaviors, including increased cognitive flexibility and reduced anxiety-like behaviors, but not depressive-like behaviors, were also observed. …”
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4695
Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review
Published 2025-01-01“…Conclusions and implications The review enhances our understanding of the primary care clinical pharmacist service in the UK and identifies gaps in evidence, emphasising the need for empirical studies on the experiences of older people with cognitive impairment and those from minority ethnic backgrounds. …”
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4696
The effect of hindrance stressors on the emotional exhaustion among front-line healthcare workers in the recuperation period during the COVID-19 epidemic in China: a prospective cr...
Published 2022-06-01“…Inclusion criteria included worked as front-line health workers and participated in the fight against COVID-19 in Hubei; age ≥18 years; normal cognitive and comprehension abilities under physical and mental health; volunteer to participate in this study. …”
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4697
Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID
Published 2025-02-01“…Common persistent symptoms are fatigue, sleep disturbances, post-exertional malaise (PEM), pain, and cognitive problems. Long-COVID is estimated to be present in about 65 million people. …”
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4698
Safety, feasibility and initial efficacy of an app-facilitated telerehabilitation (AFTER) programme for COVID-19 survivors: a pilot randomised study
Published 2022-07-01“…Secondary outcomes included preliminary efficacy outcomes including tests of function and balance; patient-reported outcome measures; a cognitive assessment; and average daily step count. …”
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4699
Clinical Features and Genetic Characteristics of XLID Patients With KDM5C Gene Mutations: Insights on Phenotype–Genotype Correlations From 175 Previous Cases and Identification of...
Published 2025-01-01“…ABSTRACT Background X‐linked intellectual disability (XLID) is a genetically heterogeneous disorder that results in cognitive impairment and developmental delays. Mutations in the KDM5C gene have been identified as a causative factor in XLID. …”
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4700
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…Abstract Background: Melatonin (MLT) can improve mitophagy, thereby ameliorating cognitive deficits in Alzheimer’s disease (AD) patients. …”
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