Astrocytic NLRP3 cKO mitigates depression-like behaviors induced by mild TBI in mice. by Hui-Tao Miao, Jun Wang, Jing-Jing Shao, Rong-Xin Song, Wen-Guang Li, Jian-Kai Sun, Shi-Yan Jia, Dong-Xue Zhang, Xiao-Ming Li, Jian-Yong Zhao, Li-Min Zhang

“…Our prior research suggests that Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)-related neuroinflammation, modulated by glial cells such as astrocytes, is likely to play a crucial role in the progression of anxiety and cognitive dysfunction. However, there is limited understanding of the potential of astrocytic NLRP3 in treating depression under mild TBI condition. …”
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Exploring clinicians’ perspectives on the ‘Obstetric Anal Sphincter Injury Care Bundle’ national quality improvement programme: a qualitative study by Ipek Gurol-Urganci, Nick Sevdalis, Edward Morris, Posy Bidwell, Ranee Thakar, James M Harris, Louise Silverton, Alexandra Hellyer, Robert Freeman, Vivienne Novis

“…Gaps were identified in clinicians’ knowledge and experience of intrapartum perineal management.Conclusions Adoption of the OASI Care Bundle was associated with a number of cognitive and interpersonal factors, such as personal values, interprofessional working and how the intervention was launched; which both facilitated and impeded adoption. …”
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Multi-dimensional outcomes following extracorporeal cardiopulmonary resuscitation by Tharusan Thevathasan, Vanessa Wahl, Joshua Boettel, Megan Kenny, Julia Paul, Sophie Selzer, Abdulla Al Harbi, Eva-Maria Dorsch, Heinrich Audebert, Matthias Rose, Christoph Paul Klapproth, Sonia Lech, Katharina Schmitt, Steffen Desch, Ulf Landmesser, Ralf Westenfeld, Fabian Voss, Carsten Skurk

“…However, long-term effects on cardiac, cognitive, physical and psychological health need further study. …”
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Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium by V. A. Ivanisenko, N. V. Basov, A. A. Makarova, A. S. Venzel, A. D. Rogachev, P. S. Demenkov, T.  V. Ivanisenko, M. A. Kleshchev, E. V. Gaisler, G. B. Moroz, V. V. Plesko, Y. S. Sotnikova, Y. V. Patrushev, V. V. Lomivorotov, N. A. Kolchanov, A. G. Pokrovsky

“…Postoperative delirium (POD) is considered one of the most severe complications, resulting in impaired cognitive function, extended hospitalization, and higher treatment costs. …”
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Exploring the Pathophysiology, Diagnosis, and Treatment Options of Multiple Sclerosis by Simone Lorenzut, Ilaria Del Negro, Giada Pauletto, Lorenzo Verriello, Leopoldo Spadea, Carlo Salati, Mutali Musa, Caterina Gagliano, Marco Zeppieri

“…Demyelination interferes with the ability of the CNS to transmit signals, which can cause a variety of neurological symptoms, including impaired motor function, sensory deficiencies, and cognitive decline. Developing tailored therapeutics requires understanding the underlying processes guiding the course of the disease. …”
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A phase II double-blind multicentre, placebo-controlled trial to assess the efficacy and safety of alpelisib (BYL719) in paediatric and adult patients with Megalencephaly-CApillary... by Jean-Marc Treluyer, Benedicte Demeer, Laurence Faivre, Marc Bardou, Nathalie Boddaert, Paul Kuentz, Florence Petit, Christine Francannet, Pierre Vabres, Nadia Bahi-Buisson, Estelle Colin, Laurent Guibaud, Romaric Loffroy, Maxime Luu, Caroline Racine, Aurore Garde, Philippe Khau Van Kien, Aurore Curie, Nawale Hadouiri, Aurélie Espitalier, Agnès Maurer, Maud Carpentier, Adélaide Rega, Mouna Chebbi, Julie Charligny, Guillaume Canaud, Camille Fleck, Amelie Cransac, Elise Boucher-Brischoux, Adélaïde Brosseau-Beauvir, Florian Cherik, Alice Phan, Michaela Semeraro, Marion Nys, Charles Joris Roux, Alinoë Lavillaureix, Isabelle Maruani

“…During its development, in patients with the MCAP subgroup of PROS, there was no specific, standardised evaluation of the effect on neuro-cognitive functioning. Moreover, it remains unknown if the molecule crosses the blood-brain barrier. …”
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Therapeutic Efficacy of <i>Lavandula dentata</i>’s Oil and Ethanol Extract in Regulation of the Neuroinflammation, Histopathological Alterations, Oxidative Stress, and Restoring Ba... by Aziza Antar, Eman S. Abdel-Rehiem, Areej A. Al-Khalaf, Abdelaziz S. A. Abuelsaad, Mohamed Abdel-Gabbar, Gaber M. G. Shehab, Ayman M. Abdel-Aziz

“…<b>Background/Objectives</b>: Despite the availability of antiepileptic drugs (AEDs) that can manage seizures, they often come with cognitive side effects. Furthermore, the role of oxidative stress and neuroinflammatory responses in epilepsy and the limitations of current AEDs necessitate exploring alternative therapeutic options. …”
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Cross-sectional design and protocol for Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) by Gerald McGwin, Linda M Zangwill, Nicholas Evans, Shannon McWeeney, Cecilia S Lee, Bhavesh Patel, Jeffrey C Edberg, Cynthia Owsley, Aaron Lee, Cecilia Lee, Sally L Baxter, Michael Snyder, Samantha Hurst, Nicole Ehrhardt, Christopher Chute, Dawn S Matthies, Julia P Owen, Amir Bahmani, Sally Baxter, Edward Boyko, Aaron Cohen, Jorge Contreras, Garrison Cottrell, Virginia de Sa, Jeffrey Edberg, Irl Hirsch, Michelle Hribar, T.Y. Alvin Liu, Bonnie Maldenado, Sara Singer, Bradley Voytek, Joseph Yracheta, Linda Zangwill

“…Data are collected in a multivariable protocol containing over 10 domains, including vitals, retinal imaging, electrocardiogram, cognitive function, continuous glucose monitoring, physical activity, home air quality, blood and urine collection for laboratory testing and psychosocial variables including social determinants of health. …”
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The pattern of elementary teachers' insight in online education, using foundational data theory by reyhaneh bazrafshan delijan, Mohammad Ghafari Mejlej, seyyed javad mortazavi amiri

“…The category of online education path has been extracted in the section of strategies; the realization of cognitive goals has been extracted in the section of program-oriented concepts and dynamic planning items; and opportunism of online education, transparency in the acquisition of professional skills, and technology-oriented education have been extracted in the section of contextual conditions in the educational concept; the technical adaptability of schools and the ability to plan online education have been extracted in the concept of knowledge of resources and equipment; and strengthening self-efficacy, strengthening professional self-monitoring have been extracted in the topic of consequences in the scientific and technical category and the cognitive concept of understanding timely thinking in decision-making. …”
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qPRF: A system to accelerate population receptive field modeling by Sebastian Waz, Yalin Wang, Zhong-Lin Lu

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Application of RhBMP-2 in Percutaneous Endoscopic Posterior Lumbar Interbody Fusion by Yunsheng Chen, Canhua Xu, Yaohong Wu, Jiangyou Shi, Rongchun Chen

“…The degree of vertebral body slippage was significantly reduced in both groups, and the RhBMP-2 group was significantly lower than the control (P < 0.05). The cognitive function, social function, physiological function, and mental health were evidently improved in both groups 12 months post-operation and were significantly higher in the RhBMP-2 group than in the control (P < 0.05). …”
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Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes by Youssef M. Zohdy, Tomas Garzon-Muvdi, Jonathan A. Grossberg, Daniel L. Barrow, Brian M. Howard, Gustavo Pradilla, Firas H. Kobeissy, Stephen Tomlinson, Ali M. Alawieh

“…Similar findings were observed with functional and cognitive outcomes, showing R2 values of 0.58, 0.7, 0.54, and 0.7 for neurological severity scores, corner tasks, passive avoidance, and novel object recognition tasks, respectively (P < 0.001). …”
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Prevalence of Intestinal Parasites and Associated Factors Among Public Primary Second‐Cycle Schoolchildren in Debre Markos Town, Northwest Ethiopia: A Cross‐Sectional Study by Abtie Abebaw, Gebreselassie Demeke, Hylemariam Mihiretie Mengist, Mengistu Endalamaw, Gizew Damtie Demeke

“…The burden of intestinal parasites is worse in schoolchildren, which leads to absenteeism from school, lower cognitive ability, affects academic performance, and causes malnutrition and anemia. …”
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Cross-border mangrove dynamics and management in the Beibu Gulf: Long-term remote sensing observation using object-oriented deep learning by Wenna Gao, Chunyan Lu, Nuocheng Yang, Yuqi Wu, Kexin Wu, Zhangjuan Chen

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Impact of Prenatal Stress on Neuroendocrine Programming by Odile Viltart, Christel C. A. Vanbesien-Mailliot

“…Over the past decade, increased scientific activities have been devoted to deciphering the obvious link between states of maternal stress and the behavioral, cognitive, emotional, and physiological reactivity of the progeny. …”
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Impact of non-invasive oxygen reserve index versus standard SpO2 monitoring on peripheral oxygen saturation during endotracheal intubation in the intensive care unit: Protocol for... by Hugo Hille, Aurélie Le Thuaut, Pierre Asfar, Quentin Quelven, Emmanuelle Mercier, Anthony Le Meur, Jean-Pierre Quenot, Virginie Lemiale, Grégoire Muller, Martin Cour, Alexis Ferré, Asael Berge, Anaïs Curtiaud, Maxime Touron, Gaetan Plantefeve, Jean-Charles Chakarian, Jean-Damien Ricard, Gwenhael Colin, Arthur Orieux, Patrick Girardie, Mathieu Jozwiak, Manon Rouaud, Camille Juhel, Jean Reignier, Jean-Baptiste Lascarrou, CRICS-TRIGGERSEP Network

“…Secondary outcomes include cognitive function on day 28. Assuming a 10% standard deviation for the lowest SpO2 value in the control group, no missing data, and crossover of 5% of patients, with the bilateral alpha risk set at 0.05, including 950 patients will provide 85% power for detecting a 2% between-group absolute difference in the lowest SpO2 value. …”
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ŽINOJIMO SOCIALUMO PROBLEMA ŠIUOLAIKINĖJE SOCIALINĖJE EPISTEMOLOGIJOJE: DU POŽIŪRIAI by Audronė Rimkutė

“…In other words, his knowing agent is an individual “cognitive mechanism”, and only his received “input” is social. …”
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Cross-agency working when conducting a pragmatic RCT for older victims of crime: our experiences and lessons learned by Marc Serfaty, Jessica Satchell, Gloria K. Laycock, Chris R. Brewin, Marta Buszewicz, Gerard Leavey, Vari M. Drennan, Jonathan Cooke, Anthony Kessel

“…Staff from the mental health charity were trained to deliver a manualised cognitive-behaviourally informed Victim Improvement Package (VIP) to be compared against treatment as usual (TAU). …”
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Desregulación emocional en población con TDAH; una aproximación teórica/Emotional dysregulation in the population with ADHD. A Theoretical Approach by Alejandra Alpizar

“…English  Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, whose nuclear symptoms constitute inattention, hyperactivity and impulsivity, the latter may be verbal, motor and cognitive, but also emotional, expressed by emotional dysregulation, which affects a person’s ability to emotionally self-regulate and inhibit emotions. …”
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Utilidad de la música en la preparación psicólogica de los deportistas / Usefulness of Music in the Psychological Preparation of Athletes by Francisco Enrique García-Ucha, Leopoldo Ferrer-Maldonado

“…Music is described as holding an explicit and direct influence on affective, cognitive and behavioral processes in athletes. It allows regulation of motivation and emotion, reduces perceived exertion, increases the amount of exercise performed, focuses the attention and improves recovery after exercise. …”
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