Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases by Fangyuan Wang, Zhou Jing, Qingyi Wang, Minghe Li, Bingqi Lu, Ao Huo, Chenglin Zhao, Huanyu Zhou, Wulong Liang, Weihua Hu, Xudong Fu

“…ABSTRACT Background Neurodegenerative diseases involve progressive neuronal dysfunction and cognitive decline, posing substantial global challenges. …”
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Impulsivity, Sensation Seeking, and Risk-Taking Behaviors among HIV-Positive and HIV-Negative Heroin Dependent Persons by Koosha Paydary, Somayeh Mahin Torabi, SeyedAhmad SeyedAlinaghi, Mehri Noori, Alireza Noroozi, Sara Ameri, Hamed Ekhtiari

“…In BIS, HIV-positive group scored significantly higher in cognitive impulsivity (CI) (P=0.03) and nonplanning impulsivity (NPI) (P=0.05) in comparison to HIV-negative group. …”
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Validation of the detection of elder abuse through emergency care technicians (DETECT) screening tool: a study protocol by Melvin D Livingston, Brad Cannell, Julie Weitlauf, Jason Burnett, Megin Parayil, Jennifer Reingle Gonzalez

“…Follow-up interviews will consist of a medic-led semistructured interview designed to assess the older adult’s likelihood of abuse exposure, physical/mental health status, cognitive functioning, and to systematically evaluate the quality and condition of their physical and social living environment. …”
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ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation by Yuan Chang, Yihua He, Di Wang, Kunxue Zhang, Yuzhen Zhang, Zhentong Li, Shuxin Zeng, Sheng Xiao, Suyue Pan, Kaibin Huang

“…Abstract Delayed radiation-induced brain injury (RIBI) characterized by progressive cognitive decline significantly impacts patient outcomes after radiotherapy. …”
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Psychometric accuracy of the Dutch Child and Adolescent Trauma Screener by Lieke H. Kooij, Irma M. Hein, Cedric Sachser, Samantha Bouwmeester, Madelief Bosse, Ramón J. L. Lindauer

“…Furthermore reliability, convergent-divergent patterns and diagnostic test accuracy were examined.Results: The underlying DSM-5 factor structure with four symptom clusters (re-experiencing, avoidance, negative alterations in mood and cognitions, hyperarousal) was supported by CFA showing a good fit for the selfreport (CFI = .95, TLI = .94), and an acceptable fit for the caregiver report (CFI = .90, TLI = .89). …”
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Bridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders by Haixia Luo, Junzhuo Chen, Jiaojiao Liu, Wei Wang, Chuanke Hou, Xingyuan Jiang, Juming Ma, Fan Xu, Xire Aili, Zhongkai Zhou, Hongjun Li, Hongjun Li, Hongjun Li

“…HAND includes a variety of cognitive, motor, and behavioral disorders, severely impacting patients’ quality of life and social functioning. …”
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Investment behavior in the Egyptian stock market: The impact of social media on investor decision-making by Abdelrehim Awad, Adel Fathy Aziz, Talaat Rashad Shma

“…Regulators should promote investor education on the cognitive biases linked to social media engagement, while financial advisors must address its influence on client decision-making. …”
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Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease by Márton Kovács, Attila Makkos, Zsuzsanna Aschermann, József Janszky, Sámuel Komoly, Rita Weintraut, Kázmér Karádi, Norbert Kovács

“…Severity of PD symptoms was assessed by MDS-UPDRS, UDysRS, Non-Motor Symptoms Scale, PDSS-2, Hamilton Anxiety Scale, Montgomery-Asberg Depression Rating Scale, Lille Apathy Rating Scale, and Addenbrooke Cognitive Examination. HRQoL was assessed by PDQ-39 and EQ-5D. …”
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Effectiveness of a harmonica-integrated, tele-supervised home-based pulmonary rehabilitation program on lung function and comprehensive health outcomes in patients with chronic obs... by Qiuxuan Zeng, Xiaohong Lin, Wenli Chen, Daniel Yee Tak Fong, Junxin Li, Jiaying Li, Jiaying Li

“…A total of 248 adult patients (with a clinical diagnosis of COPD but without severe comorbidities, significant cognitive impairments, and prior experience with the intervention components) will be randomized in a 1:1 ratio to either a harmonica-integrated PR group (intervention) or a standard PR group (control) for 6 months of home-based, tele-supervised training. …”
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Preferences of people with type 2 diabetes for telemedical lifestyle programmes in Germany: protocol of a discrete choice experiment by Veronika Gontscharuk, Andrea Icks, Michael Roden, Markus Vomhof, Sandra Grobosch, Jana Sommer, Jan Dyczmons

“…To develop the design of the DCE, we conducted pilot work involving healthcare experts and in particular people with T2DM using cognitive pretesting. The final DCE is being implemented within a randomised controlled trial for investigating whether participation in a telemedical lifestyle intervention programme sustainably improves the HbA1c values in 850 members of a large German statutory health insurance with T2DM. …”
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Thyroid disorders in patients with human immunodeficiency virus infection: a meta-analysis by Sagad O. O. Mohamed, Khalid Osman Mohamed, Ayoub A. B. Mohamed, Ali E. A. Mohamed, Solafa S. M. Salih, Duaa A. S. Ibrahim, Samia I. E. Mursal, Aseel E. B. Abdhameed, Ahmed A. O. Mahmoud, Khadeja F. Abdallah, Khalid S. K. Salih, Ahmed S. E. E. Abdelrahman, Mohamed S. K. Salih, Yusra E. A. Elmobashir, Mahmoud A. M. Abdelrahman, Amgad I. A. Mohamed, Hanaa A. M. Fadil

“…Abstract Background Thyroid disorders have significant clinical sequelae, including impaired growth in children, metabolic abnormalities, and impaired cognitive function. However, available studies on burden of thyroid diseases in people with human immunodeficiency virus (HIV), particularly its prevalence and its interaction with HIV related factors (like CD4 count), are controversial. …”
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Anaemia in the Hospitalized Elderly in Tanzania: Prevalence, Severity, and Micronutrient Deficiency Status by Clara Chamba, Ahlam Nasser, William F. Mawalla, Upendo Masamu, Neema Budodi Lubuva, Erius Tebuka, Pius Magesa

“…Anaemia exhorts negative consequences to functional ability of elderly patients, both physically and cognitively. The purpose of this study was to determine the prevalence of anaemia, severity, and micronutrient deficiency status in the elderly hospitalized patients in Tanzania. …”
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User-Centric Radio Access Technology Selection: A Survey of Game Theory Models and Multi-Agent Learning Algorithms by Giuseppe Caso, Ozgu Alay, Guido Carlo Ferrante, Luca De Nardis, Maria-Gabriella Di Benedetto, Anna Brunstrom

“…User-centric radio access technology (RAT) selection is a key communication paradigm, given the increased number of available RATs and increased cognitive capabilities at the user end. When considered against traditional network-centric approaches, user-centric RAT selection results in reduced network-side management load, and leads to lower operational costs for RATs, as well as improved quality of service (QoS) and quality of experience (QoE) for users. …”
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Clinical and radiological characteristics and 1-year self-reported outcomes from patients with encephalitis and coronavirus disease 2019 by Nathane Braga da Silva Rezende, Fernanda Gomes de Queiroz Barros-Aragão, Talita Pinto, Viviane Tavares Carvalho Crelier, Marcos Ravi Figueiredo, Carlos Otávio Brandão, Andrea Silveira de Souza, Fernanda Tovar-Moll, Gabriel R. de Freitas

“…Conclusion Encephalitis associated with severe acute respiratory syndrome coronavirus 2 infection is rare but responsible for chronic sequelae in cognitive and motor aspects. The pathophysiology seems to be associated with both the immune-mediated and inflammatory processes, and the low frequency of paraclinical findings demands a high clinical suspicion.…”
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Nurse-led patient-centred intervention to increase written advance directives for outpatients in early-stage palliative care: study protocol for a randomised controlled trial with... by Katia Iglesias, Catherine Busnel, Florian Dufour, Sophie Pautex, Laurence Séchaud

“…A qualitative study will be conducted to understand the cognitive and emotional processes and experiences of nurses, patients and relatives confronted with end-of-life discussions. …”
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Brief intervention to reduce fatigue impact in patients with inflammatory arthritis: design and outcomes of a single-arm feasibility study by Paul Ewings, Emma Dures, Sarah Hewlett, Joanna Thorn, Mwidimi Ndosi, Siobhan Creanor, Jo Adams, Lance M McCracken, Joe Lomax, Susan Bridgewater, Bryan Abbott, Alice Berry, Marie Urban

“…We developed a manualised, one-to-one, cognitive–behavioural intervention, delivered by rheumatology health professionals (RHPs). …”
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Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia by Hang Zhang, Sheng Yang, Yi-Lin Lu, Luo-Qi Zhou, Ming-Hao Dong, Yun-Hui Chu, Xiao-Wei Pang, Lian Chen, Lu-Lu Xu, Lu-Yang Zhang, Li-Fang Zhu, Ting Xu, Wei Wang, Ke Shang, Dai-Shi Tian, Chuan Qin

“…The expression of critical molecule in microglia was regulated using Cx3cr1CreER mice and clinical-stage drugs to assess its effect on white matter injury and cognitive function. Results: Our study identified nuclear factor erythroid-2 related factor 2 (Nrf2) as a key transcription factor regulating oxidative stress and functional phenotype in microglia. …”
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Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors by Shudong Lin, Guanghua Zhu, Juan Xie, Xuanwei Wen, Limin Deng, Sijing Li, Guozhi Liu, Feiyan Wang, Shuangxi Chen, Zijian Xiao

“…ABSTRACT Background and Purpose Cerebral amyloid angiopathy (CAA) is recognized as a major contributor to progressive cognitive decline and cerebral hemorrhages in the elderly population. …”
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Advancing Building and Construction Higher Education: The Online Real-Time Block Model’s Contributions to Professional Skills, Gender Equity, and Industry Preparedness by Nima Izadyar, Le Li, Shuo Chen, Darryl O’Brien

“…Future research may explore developing hybrid models to optimize cognitive load further, improve accessibility, and enhance flexibility.…”
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Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review by Alice Burnand, Abi Woodward, Vladimir Kolodin, Jill Manthorpe, Yogini Jani, Mine Orlu, Cini Bhanu, Kritika Samsi, Victoria Vickerstaff, Jane Wilcock, Jane Ward, Greta Rait, Nathan Davies

“…Conclusions and implications The review enhances our understanding of the primary care clinical pharmacist service in the UK and identifies gaps in evidence, emphasising the need for empirical studies on the experiences of older people with cognitive impairment and those from minority ethnic backgrounds. …”
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