Development of a Japanese version of the patient perceptions of deprescribing – Short form by Mio Kushibuchi, Kenya Ie, Masaki Takahashi, Amy M. Linsky, Steven M. Albert

“…Methods The SF‐PPoD was translated, back‐translated, and assessed in a cognitive interview. We conducted a cross‐sectional survey with 196 patients aged 65 years or older with five or more medications using the Japanese version to test for reliability and validity. …”
Get full text

Gene networks and metabolomic screening analysis revealed specific pathways of amino acid and acylcarnitine profile alterations in blood plasma of patients with Parkinson’s disease... by A. A. Makarova, P. M. Melnikova, A. D. Rogachev, P. S. Demenkov, T. V. Ivanisenko, E. V. Predtechenskaya, S. Y. Karmanov, V. V. Koval, A. G. Pokrovsky, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…To identify potential mechanisms of amino acid and acylcarnitine metabolism disorders in PD and VP, regulatory gene networks were reconstructed using ANDSystem, a cognitive system. Regulatory pathways to the enzymes converting significant metabolites were found from PD­specific genetic markers, VP­specific genetic markers, and the group of genetic markers common to the two diseases. …”
Get full text

Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury by Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Ramasamy Thangavel, Sudhanshu P. Raikwar, Smita A. Zaheer, Shankar S. Iyer, Casey Burton, Donald James, Asgar Zaheer

“…Though the survival rate and the neurological deficiencies have shown significant improvement in many TBI patients with newer therapeutic options, the underlying pathophysiology of TBI-mediated neuroinflammation, neurodegeneration, and cognitive dysfunctions is understudied. In this study, we analyzed mast cells and neuroinflammation in weight drop-induced TBI. …”
Get full text

Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder by Jokthan Guivarch, Mélanie-Lou Persia, Laure Le Treut, Pauline Grandgeorge, Federico Solla, Hugo Pergeline, Michel Dugnat, Florence Askenazy, François Poinso, Arthur Varoquaux, Arnaud Fernandez

“…Postpartum depression can adversely affect the first interactions with the child and, consequently, their emotional, social, and cognitive development. Objectives: First, to describe the developmental profile of six-month-old infants of mothers suffering from severe postpartum depression, and, second, to compare the development of infants whose mothers suffer from depression with or without bipolar disorder. …”
Get full text

Microbiota, parasitic infections and their relationship with nutritional status and neurocognitive functioning in children from Ecuador—Proyecto Guagua: research protocol for a cro... by Sandra Victoria Abril-Ulloa, Tannia Valeria Carpio-Arias, Renata Alejandra Alvarado-Barba, Cristina Gabriela Ríos-Romero, Pamela Vinueza-Veloz, Sueny Paloma Lima-dos-Santos, Sueny Paloma Lima-dos-Santos, Igor Eduardo Astudillo-Skliarova, Igor Eduardo Astudillo-Skliarova, Ruth Irene Arias-Gutiérrez, Manuel Pérez-Quintana, Henk-Jan Boele, Henk-Jan Boele, Henk-Jan Boele, María Fernanda Vinueza-Veloz

“…Enrolled children undergo comprehensive evaluations assessing nutritional status, body composition, motor learning, social skills, cognitive ability, sleep habits, and physical activity. …”
Get full text

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer’s Disease by Xi Mei, Mengxiang Yang, Lina Zhu, Qi Zhou, Xingxing Li, Zhongming Chen, Chenjun Zou

“…Retina abnormalities are related to cognitive disorders in patients with Alzheimer’s disease (AD). …”
Get full text

Patients’ satisfaction and efficacy of modern conventional hearing aids: A comprehensive analysis of the self-reported user experiences in adult people by Daniele Portelli, Cosimo Galletti, Sabrina Loteta, Leonard Freni, Francesco Ciodaro, Angela Alibrandi, Giuseppe Alberti

“…Objective: Hearing loss is a widespread condition that impacts the quality of life, affecting communication, social interactions, and cognitive functions. This study aimed to evaluate the subjective benefit and satisfaction of using hearing aids among patients since the adoption rate of hearing aids remains low. …”
Get full text

Delirium management and current practice among Intensive Care Units Doctors, Khartoum [version 3; peer review: 1 approved, 2 approved with reservations] by Mudawi Mohammed Ahmed Abdallah, Sheema Hamid Seidna Hamid, Hana Eltayeb Salih Elamin, Ghada Omer Hamad Abd El-Raheem

“…Delirium is a brain dysfunction characterized by attention and cognitive disturbances in a fluctuating manner. The international guidelines recommend daily screening for delirium. …”
Get full text

RELATIONSHIP BETWEEN NATIVE INTELLIGENCE (NI) AND ARTIFICIAL INTELLIGENCE (AI): AN OVERVIEW by Bawallah Musa Adesola, Odole, Kehinde, Ilugbo, Stephen Olubusol, DareC, Ojo Omonijo, Owele Boye Agatha, Hadiza Mali Bukar

“…Western Ideologists tend to attribute Native Intelligence (NI) to Africans / third-word concepts, indistinctly fixed to value and belief that aided social cultural, religious, political economic, spiritual evolution, and ancient societies, However, the Emergence of Artificial intelligence (AI) being the capacity of a computer system or machine to mimic human cognitive such as learning and solving problems, through a computer system that uses mathematics and logic, to simulate the reasoning ability of man, through the process of learning from new information, and transforming such information into actions, by making decisions that has increasingly enhanced the quality of human life. …”
Get full text

Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 1 approve... by Spyridon Siafis, Johannes Schneider-Thoma, Alexandra Bannach-Brown, Oliver D. Howes, Virginia Chiocchia, Ulf Tölch, Natascha I. Drude, Sabine M. Hölter, Andrea de Bartolomeis, Anthony C. Vernon, Georgia Salanti, Sridhar Natesan, Stefan Leucht, Irene Bighelli, Sameer Jauhar, Ioannis Mantas, Josef Priller, Francesca Tinsdeall, Wulf-Peter Hansen, Fiona J. Ramage, Nobuyuki Nomura, Malcolm R. Macleod

“…We will examine other behavioural readouts of relevance for psychosis as secondary outcomes, such as social interaction and cognitive function. We will synthesize the data using multi-level meta-analysis with a predefined random-effects structure, considering the non-independence of the data. …”
Get full text

Passive hyperthermia alters the resting-state functional connectivity of mouse brain by Yang Ruan, Kai Liu, Bo Li, Shaowen Qian, Hongxia Lei, Yao Xing, Gang Sun

“…The ROI-ROI FC analysis showed that passive hyperthermia exposure significantly reduced the FC strength in the overall brain represented by CN, SN, DMN of mice.Conclusion Prolonged exposure to high temperature has a greater impact on the overall perception and cognitive level of mice, which might help understand the relationship between neuronal activities and physiological thermal sensation and regulation as well as behavioral changes.…”
Get full text

High-intensive physical rehabilitation approach in children and adolescents with acquired brain injury during subacute phase (REHABILITY): a feasibility study protocol by Jan Willem Gorter, Christiaan Gmelig Meyling, Olaf Verschuren, Ingrid Rentinck, Irene van der Steen, Raoul Engelbert

“…Frequent and systematic assessment (baseline, each consecutive 6 weeks -if applicable- and at discharge) through a core set of outcome measures will provide insights into the degree of recovery of motor and cognitive functioning. We use descriptive and inferential statistics and thematic content analysis for analysis of the data.Ethics and dissemination The study has been approved by the Medical Ethics Research Committee of the University Medical Hospital, Utrecht (reference number: 23U-0628). …”
Get full text

Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions by Magdalena Rosa-Bończak Rosa, Patrycja Marta, Filip Maciej Huzarski, Klaudia Anna Pawełek, Gabriela Monika Ferfecka, Agata Ossolińska, Natalia Morawiecka, Lucyna Stolarska, Oliver Carlton, Weronika Kłosowicz

“…Recent findings emphasize that mindfulness techniques, cognitive-behavioral therapy, improved sleep hygiene, and even melatonin supplementation may contribute to the success of infertility treatments, including assisted reproductive techniques. …”
Get full text

Key regions aberrantly connected within cerebello-thalamo-cortical circuit and their genetic mechanism in schizophrenia: an fMRI meta-analysis and transcriptome study by Yarui Wei, Ziyu Wang, Kangkang Xue, Xiaoyu Niu, Longyao Ma, Shaoqiang Han, Baohong Wen, Yong Zhang, Huafu Chen, Jingliang Cheng

“…These findings suggest key regions aberrantly connected within CTCC in SCZ, which may indicate the neural substrate of “cognitive dysmetria” and be a consequence of complex interactions from a wide range of genes with diverse functional features.…”
Get full text

The Feasibility of Telephone-delivered Self-management Intervention in Multiple Sclerosis by Mozaffar Hosseininezhad, Sajjad Saadat, Fatemeh Younesi Rostami, Roghaye Zare, Ali Bonyad, Masoumeh Qanbary Joopish, Alia saberi, Fateme Shafaee

“…The telephone-delivered self-management intervention, delivered through educational video files and telephone calls, included evidence-based cognitive behavioral therapy and psychological strategies to assist participants. …”
Get full text

A mind-body resilience intervention for emotional distress in cardiac arrest survivors and their informal caregivers – Recovering together after cardiac arrest: Protocol for an ope... by Danielle La Camera, Jonathan Elmer, Sarah M. Perman, Michael W. Donnino, Ona Wu, Robert A. Parker, Ana-Maria Vranceanu, Alexander M. Presciutti

“…Inclusion criteria: Survivors - sufficient cognitive status to meaningfully participate (Short Form of the Mini Mental State Exam ≥5). …”
Get full text

Opinions on hypertension care and therapy adherence at the healthcare provider and healthcare system level: a qualitative study in the Hague, Netherlands by Mattijs E Numans, Michiel L Bots, Sytske van Bruggen, Hedwig M M Vos, Rimke C Vos, Guy Rutten, Saskia E van Grondelle, Judith Meijer, Erik van Duin

“…Data were analysed using the theoretical domains framework (TDF) and the behaviour change wheel.Setting and participants Participants were from a highly urbanised city environment (the Hague, Netherlands), and included nine primary care physicians, six practice nurses and five secondary care physicians involved in hypertension care.Results Nine domains on the TDF were found to be relevant at the healthcare provider level (‘knowledge’, ‘physical, cognitive and interpersonal skills’, ‘memory, attention and decision processes’, ‘professional, social role and identity’, ‘optimism’, ‘beliefs about consequences’, ‘intention’, ‘emotion’ and ‘social influences’) and two domains (‘resources’ and ‘goals’) were found to be relevant at the system level. …”
Get full text

Total Adiponectin Is Inversely Associated with Platelet Activation and CHA2DS2-VASc Score in Anticoagulated Patients with Atrial Fibrillation by Roberto Carnevale, Daniele Pastori, Mariangela Peruzzi, Elena De Falco, Isotta Chimenti, Giuseppe Biondi-Zoccai, Ernesto Greco, Antonino G. M. Marullo, Cristina Nocella, Francesco Violi, Pasquale Pignatelli, Camilla Calvieri, Giacomo Frati

“…Exclusion criteria were as follows: prosthetic heart valves, cardiac revascularization in the previous year, severe cognitive impairment, chronic infectious or autoimmune diseases, and active cancer. …”
Get full text

Breakfast Intake and Factors Associated with Adherence to the Mediterranean Diet among Lebanese High School Adolescents by Rana Mounayar, Rana Jreij, Jennifer Hachem, Frida Abboud, Maya Tueni

“…The Mediterranean diet has shown to have positive health impacts on metabolic diseases and cognitive performance. However, Mediterranean countries have witnessed a decreased adherence during the past years and the adoption of a more westernized dietary pattern. …”
Get full text

Letter and Person Recognition in Freeform Air-Writing Using Machine Learning Algorithms by Huseyin Kunt, Zeki Yetgin, Furkan Gozukara, Turgay Celik

“…This analysis has potential applications in early childhood education for assessing cognitive and psychomotor skills, as well as in user authentication. …”
Get full text