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4121
Clinicopathological characteristics and gene mutations in 11 patients with lipoprotein glomerulopathy
Published 2024-12-01“…This study aimed to investigate APOE gene mutations and the clinicopathological features in eleven LPG patients.Methods Clinicopathological and follow-up data were obtained by extracting DNA, followed by APOE coding region sequencing analysis. This study analyzed clinical and pathological manifestations, gene mutations, treatment and prognosis.Results The mean age of the eleven patients was 33.82 years. …”
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4122
Experiences of community-dwelling older adults living with multiple chronic conditions: a qualitative study
Published 2019-03-01“…Interview transcripts were analysed and coded using Thorne’s interpretive description approach.Results Five themes were identified representing older adults' experiences of living with MCC: (a) trying to stay healthy while living with MCC, (b) depending on family caregivers for support with just about everything, (c) paying the high costs of living with MCC, (d) making healthcare decisions by proxy and (e) receiving healthcare services that do not address the complex needs of persons living with MCC.Conclusions The experience of living with MCC in the community was complex and multi-faceted. …”
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4123
Context makes a difference: a qualitative study exploring how to implement a multifactorial falls prevention intervention in the community
Published 2025-02-01“…To clarify themes, data were coded in NVivo 12™. Results We identified 4 key themes related to successful implementation of a multifactorial falls prevention intervention in the community setting: (1) stakeholder involvement and participation, (2) Fostering awareness, beliefs, knowledge, and skills for falls prevention, (3) working proactively and (4) communication, collaboration, coordination and financing care. …”
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4124
Gender disparity in living organ donation: a qualitative analysis of experiences and perceptions of female donors in Pakistan
Published 2025-02-01“…Objectives This study aims to explore and analyse the interplay of sociocultural, psychological and institutional factors, gender roles and power dynamics in shaping the decision-making processes and experiences of living kidney and liver donors in Punjab, specifically focusing on women.Design This study employed a qualitative approach, using in-depth interviews to delve into the narratives and experiences of living kidney and liver donors in Punjab.Setting Punjab Human Organ Transplantation Authority (PHOTA), Lahore, Punjab, Pakistan.Participants 17 participants registered at the PHOTA for kidney or liver donation.Results Interviews with living donors at PHOTA, Lahore, provided qualitative data, which was then systematically coded and analysed to identify recurring themes that explore the underlying social and cultural reasons for the observed gender disparity. …”
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4125
SNAP and/or WIC Participation and Diet Quality in Mother-Child Dyads living in Greater Boston after Pandemic: A Mixed-Method Study
Published 2025-02-01“…Analysis of covariance using generalized linear models was employed to compare differences in Healthy Eating Index-2015 (HEI-2015) scores based on SNAP and/or WIC participation, and thematic analysis was used for coding themes. Results: Mothers who participated in SNAP and/or WIC were more from lower socioeconomic backgrounds. …”
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4126
DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells
Published 2025-01-01“…However, the nanoplatform must guarantee both the local production of the protein and the safety of the treatment to allow an effective therapy with reduced systemic toxicity.MethodsIn order to ensure a selective delivery of nucleic acids, we developed poly(lactic-co-glycolic acid) (PLGA)-poly(vinyl alcohol) (PVA) NPs loaded with an Enhanced Green Fluorescent Protein (EGFP)-coding plasmid and covalently coated with antiCD19 recombinant antibody as a targeting mechanism. …”
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4127
Perceived barriers to reaching equity in effective access to diagnosis and treatment for women with breast cancer in Chile
Published 2025-02-01“…Interviews were transcribed, anonymized, and coded using ATLAS.Ti for deductive thematic analysis. …”
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4128
Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum)
Published 2025-01-01“…Combining re-sequencing data of 109 individuals, we identified a female-specific region, which was localized in a non-coding region, i.e., around 26-kb upstream of foxl2 gene (encoding forkhead box L2). …”
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4129
Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: a systematic guideline review
Published 2025-01-01“…Recommendations, with their strength and evidence level, were thematically coded and clustered around clinical questions using ATLAS.ti.ResultsWe included 26 CPGs from which we extracted 581 recommendations on risk assessment, non-pharmacological, and pharmacological interventions. …”
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4130
Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review
Published 2025-01-01“…MicroRNAs (miRs) and several candidate genes, including CYP11A, CYP21 and CYP17, have been linked to PCOS. Single-stranded non coding RNAs known as microRNAs have been shown to alter several cell cycle processes, including metabolism, apoptosis, differentiation and proliferation. …”
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4131
A Novel Mutation in the CYP11B1 Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy
Published 2015-01-01“…The underlying molecular defect was investigated by PCR-sequencing analysis of all coding exons and intron-exon boundary of the CYP11B1 gene. …”
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4132
In silico comparative genomic analysis unravels a new candidate protein arsenal specifically associated with Fusarium oxysporum f. sp. albedinis pathogenesis
Published 2022-11-01“…Foa 133 and Foa 9 have genomes of 56.23 Mb and 65.56 Mb with 17460 and 19514 putative coding genes. Of these genes, 30% lack functional annotation with no similarity to characterized proteins. …”
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4133
A Speed-Invariant Template-Based Approach for Estimating Running Temporal Parameters Using Inertial Sensors
Published 2025-01-01“…Thus, this study suggested that template-based approach is a valid solution for the inertial-based estimation of temporal parameters during running from slow jogging to fast sprinting. MATLAB codes and templates have been made available online.…”
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4134
Adulteration detection in cactus seed oil: Integrating analytical chemistry and machine learning approaches
Published 2025-01-01“…Therefore, combining MC simulation with RF as a robust method for detecting CO adulteration is proposed. The proposed method, coded in Python and available as open-source, offers a flexible framework for continuous adaptation with new data.…”
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4135
Stratégies pédagogiques utilisées dans la création de capsules audiovisuelles par des futurs enseignants de FLE
Published 2024-12-01“…Dans le cadre de ce projet, les professeurs de français en formation ont dû créer des vidéos explicatives sur des formes linguistiques en français, en utilisant toutes les ressources créatives que ce format permet (utilisation de codes audiovisuels, de musique, de jeux de rôle, de situations de communication réelles, etc.). …”
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4136
How and why do financial incentives contribute to helping people stop smoking? A realist review protocol
Published 2022-06-01“…Using Pawson and Tilley’s iterative realist review approach, data collected will be screened, selected, coded, analysed and synthesised into a set of explanatory theoretical findings.Ethics and dissemination Ethical approval is not required for this review as data sources to be included are previously published. …”
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4137
Patient Perceptions of Surgeon Attire, Professionalism, and Gender Bias in Pakistani Public Hospitals
Published 2025-02-01“…These findings highlight the importance of addressing gender biases in patient perceptions and developing culturally sensitive dress codes that align with expectations for both male and female surgeons to enhance trust and equity in healthcare settings. …”
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4138
Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma.
Published 2025-01-01“…MicroRNAs (miRNAs) are small non-coding RNA species that are involved in regulation of mRNA expression and translation. …”
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4139
Referring psychiatric patients to occupational health services for earlier return to work – a qualitative implementation study of barriers and facilitators
Published 2025-01-01“…Data analysis consisted of analysing the sessions, systematically coding the transcribed texts according to the main domains of CFIR, thematic analysis, and identifying the overarching themes and context-related mechanisms. …”
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4140
Expanding the clinical spectrum of 19p13.3 microduplication syndrome: a case report highlighting nephrotic syndrome and literature review
Published 2025-01-01“…CMA results showed a 3.6 Mb fragment duplication (copy number: 3) in the chr19p13.3 region, containing 127 protein-coding genes (including CELF5, NFIC, SMIM24, PIAS4, ATCAY, MAP2K2, and ZBTB7A). …”
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