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3661
Structural and functional divergence of homoeologous genes in allopolyploid plant genomes
Published 2017-02-01“…Changes of individual copies can be associated with epigenetic features of the gene organization (the methylation status of the promoter region or the presence of copy-specific small interfering RNA) or can affect structure of the coding or regulatory regions of the gene. Studies on artificial allopolyploid plants showed widespread transcriptional dominance and change of the transcription level as compared with the genes of diploid parental forms. …”
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3662
Effect of Wind Loading Pattern on Shear Lag Phenomenon in Framed-Tube Building
Published 2024-02-01“…Six load cases are taken from American and Canadian codes to analyze the wind load effects on a 40-storeyed tubular building. …”
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3663
Time-Space Translation: A Developmental Principle
Published 2010-01-01“…We present a model describing that the NOM acquires transiently stable hox codes and spatial collinearity, and that morphogenetic movements then continually bring new cells from the NOM within the range of SO signals that cause transfer of the mesodermal pattern to a stable pattern in neurectoderm and, thereby, create patterned axial structures. …”
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3664
Analysis of Strong Ground Motion Characteristics for the Jishishan MS6.2 Earthquake December 18, 2023
Published 2024-01-01“…The ground motion intensity observed at the epicenter of this earthquake significantly exceeded the levels of rare and extremely rare seismic events in the current seismic design codes. The attenuation relationship of PGA obtained by regression analysis shows that ones in the 5th generation Chinese ground motion parameter zoning map for the Qinghai-Tibet region underestimate the horizontal PGA.…”
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3665
Blueprint for a high-performance biomaterial: full-length spider dragline silk genes.
Published 2007-06-01“…Phylogenetic footprinting revealed putative regulatory elements in non-coding flanking sequences. Conservation of both upstream and downstream flanking sequences was especially striking between the two paralogous black widow major ampullate silk genes. …”
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3666
MultiChem: predicting chemical properties using multi-view graph attention network
Published 2025-01-01“…Conclusion MultiChem highlights the importance of integrating both local and global structural information in predicting molecular properties, while also assessing the stability of the models across multiple datasets using various random seed values. Implementation The codes are available at https://github.com/DMnBI/MultiChem .…”
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3667
LncRNA-PVT1 enhances glucose metabolism of pediatric low-grade glioma cells through sponging miR-187-3p
Published 2024-12-01“…Studies have revealed critical roles of long non-coding RNAs (lncRNAs) in brain tumor progressions. …”
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3668
STADIUM: Species-Specific tRNA Adaptive Index Compendium
Published 2018-12-01“…In addition to about 100 species in stAIcalc, we calculated stAI values for whole coding sequences in 148 species. To enable easy access to this index, we constructed a novel web database, named STADIUM (Species-specific tRNA adaptive index compendium). …”
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3669
Suboptimal but intact integration of Bayesian components during perceptual decision-making in autism
Published 2025-01-01“…This hypothesis has gained momentum in recent years, partly because it can be implemented both at the computational level, as in Bayesian perception, and at the level of canonical neural microcircuitry, as in predictive coding. However, empirical investigations have yielded conflicting results with evidence remaining limited. …”
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3670
Transposable Elements and Genome Size Variations in Plants
Published 2014-09-01“…Although the number of protein-coding genes is not highly variable between plant taxa, the DNA content in their genomes is highly variable, by as much as 2,056-fold from a 1C amount of 0.0648 pg to 132.5 pg. …”
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3671
The Dilution Dependency of Multigroup Uncertainties
Published 2014-01-01“…The first assumed a correlation between continuous-energy and multigroup cross-sectional data and uncertainties, which is convenient for direct implementation in lattice physics codes. The second is based on a more rigorous approach involving the Monte Carlo sampling of resonance parameters in evaluated nuclear data using the TALYS software. …”
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3672
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3673
getphylo: rapid and automatic generation of multi-locus phylogenetic trees
Published 2025-01-01“…Orthologues are identified heuristically by searching for singletons (single copy genes) across all input genomes and the phylogeny is inferred from a concatenated alignment of all coding sequences by maximum likelihood. We performed a thorough benchmarking of getphylo against two existing tools, autoMLST and GTDB-tk, to show that it can produce trees of comparable quality in a fraction of the time. …”
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3674
Comparative Study on Characteristics of Urban Road Network in Station Catchment Area between China and Other Countries for Station-City Integration
Published 2022-01-01“…Except for that of the Honkong West Kowloon Station, the values for the Shapingba Station, Shanghai Hongqiao Station, and Hangzhou West Station are lower than this range. (3) Developing small-scale blocks by gridding has an optimal effect on station catchment areas within the side-length range of 47.1–97.5 m. (4) The current situation of the entire urban road network and the specifications for the design codes of the road network exhibit a certain correlation with the road network characteristics of the station catchment areas.…”
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3675
Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct
Published 2012-01-01“…Initially, cDNA corresponding to ACO1 of lowland tomato cultivar (MT1), which has high identity with ACO1 of Solanum lycopersicum in GenBank, was cloned through RT-PCR. Using a partial coding region of ACO1, one hpRNAi transformation vector was constructed and expressed ectopically under the 35S promoter. …”
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3676
Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions.
Published 2025-01-01“…We developed an SEPN1-related risk score (SRS) based on SEPN1-related long non-coding RNAs and validated its prognostic value. Drug sensitivity data and connectivity map analysis identified potential anti-glioma drugs based on the SRS.…”
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3677
Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome
Published 2013-12-01“…Besides briefly discussing the important outcomes of the comparative analyses made so far between modern humans and Neanderthals, we propose that future comparative studies may include retrotransposons, pseudogenes, and conserved non-coding regions, all of which might have played significant roles during the evolution of modern humans.…”
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3678
Comparative Molecular Field Analysis (CoMFA) for Thiotetrazole Alkynylacetanilides, a Non-Nucleoside Inhibitor of HIV-1 Double Mutant K103N/Y181C Reverse Transcriptase
Published 2009-01-01“…HIV-1 resistance to nucleoside RT inhibitors such as AZT can arise through mutations in the coding region of RT. Recently a series of thioterazolyl acetanilides were reported as potent inhibitors of HIV-1 wild type and double mutant K103N/Y181C reverse transcriptase. …”
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3679
Multi-Band mm-Wave Wearable Antenna Synthesized with a Genetic Algorithm
Published 2022-01-01“…The reference patch antenna was etched on a flexible polytetrafluoroethylene (PTFE) fabric substrate with an overall dimension of 18 mm × 18 mm × 0.6 mm and optimized the patch geometry using a binary-coded genetic algorithm. The algorithm iteratively creates a new shape of the path surface, evaluates the cost function, and returns the best-fitted geometry based on the formulated fitness function. …”
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3680
Improving emotional availability in Australian mother-toddler dyads via the Tuning in to Toddlers parenting program
Published 2025-02-01“…Baseline and 12-month follow up observation assessments for 99 mother-toddler dyads (intervention, n = 50; control, n = 49) were coded using the Emotional Availability Scales (4th edition) and analysed for between-group differences and clinically reliable change. …”
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