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3381
The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury
Published 2002-01-01“…Hybridization of the oligonucleotide to the mRNA then interferes with the normal processing of that mRNA at the ribosome or targets the RNA duplex for cleavage by the RNA digestive enzyme, ribonuclease H, resulting in greatly reduced expression of the coded protein. This effectively reduces the amount of corresponding translated protein product and experiments can be designed to examine the requirement of particular inflammatory agents in eliciting specific deleterious responses after injury, e.g., cell death.…”
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3382
Understanding the Role of Refugees' Entrepreneurship Motives and Challenges in Integration: Evidence From the Food Industry
Published 2021-12-01“…., London and Istanbul). The theme coding analysis was performed on the qualitative data, and the analysis processes revealed three main dimensions: entrepreneur integration motives, entrepreneur integration domains, and entrepreneur integration challenges. …”
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3383
A Phantom-Node Method with Edge-Based Strain Smoothing for Linear Elastic Fracture Mechanics
Published 2013-01-01“…The shape functions associated with discontinuous elements are similar to those of the standard finite elements, which leads to certain simplification with implementing in the existing codes. The phantom-node method allows modeling discontinuities at an arbitrary location in the mesh. …”
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3384
Recent advances in adipose-derived mesenchymal stem cell-derived exosomes for regulating macrophage polarization
Published 2025-02-01“…Potent anti-inflammatory substances contained in exosomes include the glycoprotein MFGE8, the cytokines such as prostaglandin E2, IL-6, and IGF, as well as non-coding nucleotides (miR-451a, miR-23, miR-30d-5p, let-7, lncRNA DLEU2, circRps5, Circ-Ptpn4, and mmu_ circ_0001359). …”
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3385
Multi-level encoding of reward, effort, and choice across the frontal cortex and basal ganglia during cost-benefit decision-making
Published 2025-02-01“…Coactive cell assemblies, ensembles of neurons that repeatedly coactivated within short time windows (<25 ms), represented the same decision variables despite the members often having diverse individual coding properties. Together, these findings demonstrate a multi-level encoding structure for cost-benefit computations where individual neurons are coordinated into larger assemblies that can represent task variables independently of their constituent components.…”
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3386
Optimized Hyper Beamforming of Linear Antenna Arrays Using Collective Animal Behaviour
Published 2013-01-01“…As compared to conventional hyper beamforming of linear antenna array, real coded genetic algorithm (RGA), particle swarm optimization (PSO), and differential evolution (DE) applied to the hyper beam of the same array can achieve reduction in sidelobe level (SLL) and same or less first null beam width (FNBW), keeping the same value of hyperbeam exponent. …”
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3387
Identification and characteristics of MYB4 transcription factor related to regulation of abiotic stress tolerance in peanut
Published 2024-06-01“…The isolated AhL14_MYB4 gene was found to be 1.1 kb long, with a 663 bp coding sequence containing 3 exons and 2 introns. …”
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3388
Neutron Interferometry at the National Institute of Standards and Technology
Published 2015-01-01“…With recent advances in quantum information processing especially quantum error correction (QEC) codes we were able to demonstrate a neutron interferometer that is insensitive to vibrational noise. …”
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3389
Complete mitochondrial genome assembly and comparative analysis of Colocasia esculenta
Published 2025-01-01“…A total of 55 genes, 157 simple sequence repeats, 29 tandem repeat sequences, 202 dispersed repeat sequences, and 625 RNA editing sites were detected. Most protein-coding genes use ATG as the start codon, and the third position of the codon tends to be A or T (U). …”
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3390
An Integrated Metaheuristic Routing Method for Multiple-Block Warehouses with Ultranarrow Aisles and Access Restriction
Published 2019-01-01“…A problem-specific routing algorithm integrating ant colony optimization (ACO) and integer-coded genetic algorithm (GA) is developed to address the newly observed limitations imposed by ultranarrow aisles and access restriction, which exist in the largest e-commerce enterprise with self-run logistics in China. …”
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3391
Modulating gene expression as a strategy to investigate thyroid cancer biology
Published 2025-01-01“…ABSTRACT Modulating the expression of a coding or noncoding gene is a key tool in scientific research. …”
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3392
A Chromosomal-level genome assembly and annotation of fat greenling (Hexagrammos otakii)
Published 2025-01-01“…A total of 22,334 protein-coding genes were predicted, with 21,619 (96.80%) functionally annotated across various protein databases. …”
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3393
Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus
Published 2021-03-01“…To improve the efficiency of 11α-hydroxycanrenone production, the CYP monooxygenase-coding gene of MF018 was predicted and cloned based on whole-genome sequencing results. …”
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3394
The association of codon 392 polymorphism in ESR2 gene with breast cancer in Iran
Published 2019-12-01“…gene are associated with breast cancer risk among Iranian women. The coding sequence in Exon 7 at ESR2 gene was looking for any variation among the Iranian breast cancer women by SSCP-PCR method. …”
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3395
Chromosome-level genome sequencing and assembly of the parasitoid wasp Leptopilina myrica
Published 2025-02-01“…By comparing the protein-coding genes of L. myrica with those of other Hymenoptera species, we gained insights into the evolutionary history of parasitoid wasps. …”
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3396
Chromosome-level genome assembly of the pine wood nematode carrier Arhopalus unicolor
Published 2025-01-01“…Furthermore, the genome contains 71.74% repeat elements and encompasses 16,450 predicted protein-coding genes. This genome sequence of A. unicolor will be a valuable resource for understanding the genetics and evolutionary history of this species and for developing effective management strategies for this PWN carrier.…”
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3397
Investigation of Soil-Structure Interaction for Design of Reinforced Concrete Structures under Earthquake Load
Published 2018-01-01“…In this study, considering the earthquake recording of 1999 Kocaeli, a 12-storey reinforced concrete structure was analyzed with rigid foundation assumption, Winkler and Modified Vlasov models. An interface was coded in MATLAB to exchange data between SAP2000 and MATLAB. …”
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3398
Microscopic Analysis of Severe Structural Rearrangements of the Plant Endoplasmic Reticulum and Golgi Caused by Overexpression of Poa semilatent virus Movement Protein
Published 2012-01-01“…Three movement proteins coded by the “triple gene block” (TGB) and named TGBp1, TGBp2 and TGBp3 have distinct functions in viral transport. …”
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3399
Changes in Immunoreactivity of Sensory Substances within the Enteric Nervous System of the Porcine Stomach during Experimentally Induced Diabetes
Published 2018-01-01“…Using double immunofluorescent labelling, it was found that acute hyperglycaemia led to significant changes in the chemical coding of stomach enteric neurons. Generally, the response to artificially inducted diabetes depended on the “kind” of enteric plexus as well as the stomach region studied. …”
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3400
MicroRNA155 in non-small cell lung cancer: a potential therapeutic target
Published 2025-02-01“…MicroRNAs (miRNAs), a large family of non-coding RNAs, play crucial roles in regulating several key biological processes, including cell proliferation, differentiation, inflammation, and apoptosis. …”
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