Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

“…Abstract A critical goal in functional genomics is evaluating which non-coding elements contribute to gene expression, cellular function, and disease. …”
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Improvement of Shelf Life and Sensory Quality of Pears Using a Specialized Edible Coating by Virgilio Cruz, Romeo Rojas, Saúl Saucedo-Pompa, Dolores G. Martínez, Antonio F. Aguilera-Carbó, Olga B. Alvarez, Raúl Rodríguez, Judith Ruiz, Cristóbal N. Aguilar

“…Fruits were analyzed to evaluate changes in their physicochemical, microbiological, and sensorial properties during 30 days of storage at room temperature. Coated pears coded as T13 (candelilla wax 3%, gum arabic 4%, jojoba oil 0.15%, and pomegranate polyphenols 0.015%) extended and improved their shelf life quality due to the minimization of the physic-chemical changes and sensorial properties. …”
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Introns: The Functional Benefits of Introns in Genomes by Bong-Seok Jo, Sun Shim Choi

“…Fourth, all introns are copied into RNAs by transcription and DNAs by replication processes, but intron sequences do not participate in protein-coding sequences. The existence of introns in the genome should be a burden to some cells, because cells have to consume a great deal of energy to copy and excise them exactly at the correct positions with the help of complicated spliceosomal machineries. …”
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Delay discounting predicts COVID-19 vaccine booster willingness by Julia G. Halilova, Samuel Fynes‑Clinton, Caitlin M. Terao, Donna Rose Addis, R. Shayna Rosenbaum

“…After controlling for demographic variables and distress level, a greater tendency to discount future rewards was associated with reduced willingness to receive a booster dose. Thematic coding revealed that the most common reason for booster willingness was protection against COVID-19, and for unwillingness was non-necessity. …”
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Biaxial Loading Capacity of H-Type Reinforced Concrete Electric Poles by Abolfazl Eslami, Moein Ramezanpour, Ehsan Hematpoury Farokhy, Mohammad Dehghani Sanij

“…The current study was aimed at developing the biaxial bending interaction curves for H-type utility poles considering the measurements stipulated by the relevant standards and codes. Towards this, two commonly used H-type electric poles (i.e., 9 and 12 m ones with a normal strength of 400 kgF) were constructed, cured, and loaded at angles of 0, 30, 60, and 90 degrees with respect to their minor principal axes. …”
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Evaluation of thermal and mechanical properties of ZnSO4-B2O3-P2O5-Ho2O3 glass-ceramics by Areej S. Alqarni, Ibrahim Bulus

“…In this study, a novel glass-ceramic (GC) obtained from ZnSO4-B2O3-P2O5-Ho2O3 composition, coded as H0.0, H0.5 and H0.8, was synthesized via molten-solidified approach. …”
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A Comparative Study of Genetic and Firefly Algorithms for Sensor Placement in Structural Health Monitoring by Guang-Dong Zhou, Ting-Hua Yi, Huan Zhang, Hong-Nan Li

“…To overcome the drawback related to the inapplicability of the FA in optimization problems with discrete variables, some improvements are proposed, including the one-dimensional binary coding system, the Hamming distance between any two fireflies, and the semioriented movement scheme; also, a simple discrete firefly algorithm (SDFA) is developed. …”
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GRB 241107A: A Giant Flare from a Close-by Extragalactic Magnetar? by James Craig Rodi, Dominik Patryk Pacholski, Sandro Mereghetti, Edoardo Arrigoni, Angela Bazzano, Lorenzo Natalucci, Ruben Salvaterra, Pietro Ubertini

“…The position of GRB 241107A has been precisely determined because it fell inside the imaging field of view of the IBIS coded mask instrument. The presence of the nearby galaxy PGC 86046 in the 3′ radius error region suggests that GRB 241107A might be a giant flare from a magnetar rather than a canonical short gamma-ray burst. …”
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High quality genome assembly and annotation (v1) of the eukaryotic terrestrial microalga Coccomyxa viridis SAG 216-4 by Kraege, Anton, Chavarro-Carrero, Edgar A., Guiglielmoni, Nadège, Schnell, Eva, Kirangwa, Joseph, Heilmann-Heimbach, Stefanie, Becker, Kerstin, Köhrer, Karl, Schiffer, Philipp, Thomma, Bart P. H. J., Rovenich, Hanna

“…Transcriptome-guided gene annotation resulted in the identification of 13,557 protein-coding genes, of which 68% have annotated PFAM domains and 962 are predicted to be secreted.…”
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Medical Image Encryption and Decryption Based on DNA: A Survey by Saja Theab Ahmed, Dalal Abdulmohsin Hammood, Raad Farhood Chisab, Nurulisma Binti Hj. Ismail

“…For this reason, protecting patient privacy and the integrity of medical images is of paramount importance. DNA Digital coding is the most popular form of cryptographic technology, and it is frequently employed to strengthen information security, and the most prevalent constraints of DNA cryptographic schemes feature a high degree of temporal and algor. …”
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A Semantic Segmentation Method for Remote Sensing Images Based on an Improved TransDeepLab Model by Jinxin Wang, Manman Wang, Kaiwei Cong, Zilong Qin

“…The model introduces a GAM attention mechanism in the coding stage, and incorporates a multi-level linear up-sampling strategy in the decoding stage. …”
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Major Achievements and Prospect of the ATLAS Integral Effect Tests by Ki-Yong Choi, Yeon-Sik Kim, Chul-Hwa Song, Won-Pil Baek

“…These tests contributed toward an understanding of the unique thermal-hydraulic behavior, resolving the safety-related concerns and providing validation data for evaluation of the safety analysis codes and methodology for the advanced pressurized water reactor, APR1400. …”
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TESLA GPUs versus MPI with OpenMP for the Forward Modeling of Gravity and Gravity Gradient of Large Prisms Ensemble by Carlos Couder-Castañeda, Carlos Ortiz-Alemán, Mauricio Gabriel Orozco-del-Castillo, Mauricio Nava-Flores

“…We compared the performance results obtained with the GPUs against a previous version coded in OpenMP with MPI, and we analyzed the results on both platforms. …”
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Image Encryption Using Lorenz Chaotic System by Daniah Abul Qahar Shakir, Ahmad Salim, Seddiq Q. Abd Al-Rahman, Ali Makki Sagheer

“…In addition, there are significant shortcomings in 3D image coding techniques. This paper proposed a method for image encrypted and decrypted electronically using the Lorenz chaotic system, the supposed algorithm was developed by using the three equations of the Lorenz system, before that, the image pixels are destroyed using reversible shifting and rotating processes to increase the randomness of the encrypted pixels and thus the difficulty of cracking the cipher. …”
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Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection? by Terry S. Elton, Sarah E. Sansom, Mickey M. Martin

“…MicroRNAs (miRNAs) are a family of small, ∼21-nucleotide long, and nonprotein-coding RNAs that recognize target mRNAs through partial complementary elements in the 3-untranslated region (3-UTR) of mRNAs and inhibit gene expression by targeting mRNAs for translational repression or destabilization. …”
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Impact of Guideline Markings on Saturation Flow Rate at Signalized Intersections by Zhengtao Qin, Jing Zhao, Shidong Liang, Jiao Yao

“…Although guideline markings are recommended in many design manuals and codes on traffic signs and markings to address these problems, the effectiveness and application conditions are ambiguous. …”
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Image Recognition and Content Comprehension in Media Accessibility: A Study on the Reception of Audiences with Limited Hearing by Farzaneh Shokoohmand, Masood Khoshsaligheh

“…As for the techniques of speaker identification, color-coding caused significantly better content comprehension scores than tagging. …”
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Experimental Study of a Low-Specific Speed Francis Model Runner during Resonance by Einar Agnalt, Petter Østby, Bjørn W. Solemslie, Ole G. Dahlhaug

“…As the turbine geometry is available to the public, it provides an opportunity for the researchers to verify their codes at resonance conditions.…”
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Sleeve gastrectomy reveals the plasticity of the human gastric epithelium by Amit Elad, Botros Moalem, Dana Sender, Aya Bardugo, Ki-Suk Kim, Yhara Arad, Haya Benhayon, Ayelet Gal Etzyoni, Nehemia Greenstein, Aviv Halfon, Sarah Knapp, Michelle Malis, Bailey Peck, Itia Samuel, Amram Kupietzky, Saleh Daher, Esther Forkosh, David Hakimian, Tiberiu Hershcovici, Nadav Ilani, Lior Katz, Moshe Rottenstreich, Elez Vainer, Yuval Ishay, Eitan Zlotnick, Abed Nasereddin, Idid Shiff, Ariel Benson, Ronit Grinbaum, Siddhartha Mishra, Shlomi Kotler, Linda C. Samuelson, Darleen A. Sandoval, Rachel Ben-Haroush Schyr, Danny Ben-Zvi

“…ECLs of SG-operated patients overexpressed genes coding for biosynthesis of neuropeptides and serotonin. …”
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Functional genomics implicates ebony in the black pupae phenotype of tephritid fruit flies by Daniel F. Paulo, Thu N. M. Nguyen, Chris M. Ward, Renee L. Corpuz, Angela N. Kauwe, Pedro Rendon, Rocio E. Y. Ruano, Amanda A. S. Cardoso, Georgia Gouvi, Elisabeth Fung, Peter Crisp, Anzu Okada, Amanda Choo, Christian Stauffer, Kostas Bourtzis, Sheina B. Sim, Simon W. Baxter, Scott M. Geib

“…Here, we present evidence from classical and modern genetics showing that the black pupae (bp) phenotype in the GUA10 strain of Anastrepha ludens is caused by a large deletion at the ebony locus, removing the gene’s entire coding region. Targeted knockout of ebony induced analogous bp phenotypes across six major tephritid agricultural pests, demonstrating that disruption of Ebony alone is sufficient to produce the mutant trait in distantly related species. …”
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