Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio by Vera Belova, Iuliia Vasiliadis, Zhanna Repinskaia, Alina Samitova, Anna Shmitko, Natalya Ponikarovskaya, Oleg Suchalko, Valery Cheranev, Shatalov Peter, Shegai Peter, Kaprin Andrey, Denis Rebrikov, Dmitriy Korostin

“…These findings assist researchers and clinicians in selecting appropriate exome capture solutions.…”
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A nomogram to predict sarcopenia in middle-aged and older women: a nationally representative survey in China by Jiayi Yang, Zihao Chen, Xinxin Dai, Liyao Jiang, Liyan Dai, Yu Zhao

“…In addition, this study constructs a nomogram to help clinicians better screen potential female patients with sarcopenia.…”
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Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report by Aya Kawasaki, MD, Hidefumi Tonoki, MD, PhD, Osamu Sasaki, MD, PhD, Yoko Matsushita, MD, PhD, Michiko Watari, MD, PhD, Nobuhiro Takahashi, MD, Satoko Fujieda, MD

“…We hope that this case report might help clinicians and genetic counselors manage individualized surveillance plans for patients with TS.…”
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Factors Associated with Placenta Praevia in Primigravidas and Its Pregnancy Outcome by Abdul Ghani Nur Azurah, Zakaria Wan Zainol, Pei Shan Lim, Mohd Nasir Shafiee, Nirmala Kampan, Wan Syahirah Mohsin, Norfilza Mohd Mokhtar, Muhammad Abdul Jamil Muhammad Yassin

“…Understanding the pregnancy outcomes of women with placenta praevia can assist clinicians in identifying patients who are at higher risk of mortality and morbidity. …”
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Psychological, psychiatric, and behavioral sciences measurement scales: best practice guidelines for their development and validation by Alberto Stefana, Stefano Damiani, Umberto Granziol, Umberto Provenzani, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Eric A. Youngstrom, Eric A. Youngstrom, Eric A. Youngstrom, Paolo Fusar-Poli, Paolo Fusar-Poli, Paolo Fusar-Poli

“…In sum, this structured approach provides researchers and clinicians with a comprehensive methodology for developing reliable, valid, and user-friendly psychological, psychiatric, and behavioral sciences measurement scales.…”
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Biomechanical and Biological Multidisciplinary Strategies in the Orthodontic Treatment of Patients with Periodontal Diseases: A Review of the Literature by Gaia Viglianisi, Alessandro Polizzi, Teresa Lombardi, Mariacristina Amato, Cristina Grippaudo, Gaetano Isola

“…By integrating periodontal considerations into orthodontic treatment planning and execution, clinicians can ensure straight teeth and a healthy and stable periodontium, ultimately leading to successful treatment outcomes and long-term oral health.…”
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Persistent intestinal myiasis caused by Oestrus ovis in a Nigerian university student: a case report by Winifred N. Adiri, Bruno Basil, Chinwe P. Onyia, Joy O. Ugwuanyi, Chinyere Azifuaku, Sam C. Iheukwumere, Olivia Obienu, Uchenna N. Ijoma, Sylvester C. Nwokediuko

“…Conclusion This case emphasizes the need for clinicians to consider rare parasitic infections such as Oestrus ovis myiasis, especially in endemic regions with poor hygiene, and highlights the importance of extended or alternative treatment protocols for resistant cases. …”
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A Review on Deep Learning for Quality of Life Assessment Through the Use of Wearable Data by Vasileios Skaramagkas, Ioannis Kyprakis, Georgia S. Karanasiou, Dimitris I. Fotiadis, Manolis Tsiknakis

“…By synthesizing current research and identifying knowledge gaps, this review provides valuable insights for researchers, clinicians, and policymakers aiming to enhance QoL assessment with DL. …”
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Challenges and Frugal Remedies for Lowering Facility Based Neonatal Mortality and Morbidity: A Comparative Study by Hippolite O. Amadi, Akin O. Osibogun, Olateju Eyinade, Mohammed B. Kawuwa, Angela C. Uwakwem, Maryann U. Ibekwe, Peter Alabi, Chinyere Ezeaka, Dada G. Eleshin, Mike O. Ibadin

“…These included application of (i) recycled incubator technology (RIT) as a measure of providing affordable incubator sufficiency, (ii) facility-based research groups, (iii) elective training courses for clinicians/nurses, (iv) independent local artisans on spare parts production, (v) power-banking and apnoea-monitoring schemes, and (v) 1/2 yearly failure-preventive maintenance and auditing system. …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…However, widespread implementation faces several challenges: (1) characterizing dynamic molecular changes across multiple biological scales; (2) developing computational methods to integrate data into DTs; (3) prioritizing disease mechanisms and therapeutic targets; (4) creating interoperable DT systems that can learn from each other; (5) designing user-friendly interfaces for patients and clinicians; (6) scaling DT technology globally for equitable healthcare access; (7) addressing ethical, regulatory, and financial considerations. …”
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Hypokalemic paralysis in an adolescent following dexamethasone and B12 injection: A case report and literature review by Keivan Sahebi, Hassan Foroozand, Mohammad Bahmei, Raziee Taghizadeh, Samane Zare, Soroor Inaloo

“…However, this hypothesis is based on a few cases, and further pathophysiological and clinical studies are needed to clarify whether B12 supplementation exacerbates hypokalemia induced by glucocorticoids or if the observation is coincidental or context-specific. Meanwhile, clinicians should be cautious when prescribing glucocorticoids, particularly in combination with B12 supplements. …”
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Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward? by Atul P. Kulkarni, Vasant C. Nagvekar, Balaji Veeraraghavan, Anup R. Warrier, Deepak TS, Jaishid Ahdal, Rishi Jain

“…This review provides a synopsis about the current burden, treatment options, and the challenges faced by the clinicians in the management of GPIs such as MRSA, Quinolone-resistant Staphylococcus, VRE, and drug-resistant pneumococcus in India.…”
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Significance of Early Postoperative Arterial Lactic Acid, Inferior Vena Cava Variability, and Central Venous Pressure in Hypovolemic Shock by Wei Lin, Xingsheng Lin, Yingfeng Zhuang, Xiaobin Pan, Chao Wu, Shujuan Zhang, Lihui Zhang, Jian Lin, Songjing Shi, Songchang Shi

“…The diagnostic value of arterial lactate is still very high and can still be used as an early warning indicator to help clinicians be alert to the microcirculatory disorders that have emerged quietly. …”
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Red Blood Cell Transfusions and Iron Therapy for Patients Presenting with Acute Upper Gastrointestinal Bleeding: A Survey of Canadian Gastroenterologists and Hepatologists by Kyle J. Fortinsky, Myriam Martel, Roshan Razik, Gillian Spiegle, Zane R. Gallinger, Samir C. Grover, Katerina Pavenski, Adam V. Weizman, Lukasz Kwapisz, Sangeeta Mehta, Sarah Gray, Alan N. Barkun

“…Transfusions were more liberal in hemodynamically unstable patients compared to stable patients (mean Hgb of 86.7 g/L versus 71.0 g/L; p<0.001). Many clinicians (24%) reported transfusing a hemodynamically unstable patient at a Hgb threshold of 100 g/L and the majority (57%) are transfusing two units of RBCs as initial management. …”
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Prevalence, risk factors, and adverse perinatal outcomes in Chinese women with preeclampsia: a large retrospective cohort study by Lin Chai, Shuai Li, Binbin Yin, Xiaojun Zhu, Bo Zhu, Kaiqi Wu

“…Conclusion This study identified the risk factors and associated adverse perinatal outcomes of PE, which providing comprehensive evidence for clinicians to manage women at risk of PE.…”
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Environmental Pollutants as Emerging Concerns for Cardiac Diseases: A Review on Their Impacts on Cardiac Health by Vinay Kumar, Hemavathy S, Lohith Kumar Dasarahally Huligowda, Mridul Umesh, Pritha Chakraborty, Basheer Thazeem, Anand Prakash Singh

“…This review explores the impact of cardiovascular disease, discussing risk-assessment methods, intervention strategies, and the challenges clinicians face in addressing pollutant-induced cardiovascular diseases. …”
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Opioid System and Epithelial–Mesenchymal Transition by Marzena Łazarczyk, Dominik Skiba, Michel-Edwar Mickael, Kinga Jaskuła, Agata Nawrocka, Piotr Religa, Mariusz Sacharczuk

“…They alleviate pain, but also pose a risk of dependency, or trigger constipation, particularly in cancer patients, who require the more potent painkillers in more advanced stages of the disease, closely linked to pain resulting from general inflammation, bone metastases, and primary or secondary tumour outgrowth-related nerve damage. Clinicians’ vigilance considering treatment with opioids is necessary, bearing in mind extensive data accumulated over decades that have reported the contribution of opioids to immunosuppression, tumour progression, or impaired tissue regeneration, either following opioid use during surgical tumour resection and post-surgical pain treatment, or as a result of other diseases like diabetes, where chronic wounds healing constitutes a challenge. …”
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Clinical Evidence in the Treatment of Obstructive Sleep Apnoea with Oral Appliances: A Systematic Review by Andrea Rossi, Antonino Lo Giudice, Camilla Di Pardo, Alberto Teodoro Valentini, Francesca Marradi, Nicola Vanacore, Cristina Grippaudo

“…Higher-quality studies are needed in order to provide additional useful guidelines for dental clinicians for OSA management.…”
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Psychometric properties of the Moroccan dialect versions of the Perceived Stress Scale and the Center for Epidemiologic Studies Depression Scale among Moroccan university students by Younes RAMI, Hicham KHABBACHE, Jamal AMRAOUI, Driss AIT ALI, Zakaria ABIDLI, Abdulmohsen MOHAMMED ABDULLAH ALKHULAYFI, Mahmood BAHRAMIZADEH, Hassan LAABOUB, Amelia RIZZO, Bouabid BADAOUI, Şeyhmus AKSOY, Lukasz SZARPAK, Murat YILDIRIM, Francesco CHIRICO

“…These findings suggest that the PSS-10 and CES-D10 are robust tools for assessing perceived stress and depression, making them valuable instruments for researchers and clinicians in the field of mental health. …”
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The impact of different ankle positions on postural balance and weight-bearing distributions during different kneeling positions by Hande Guney Deniz, Gizem İrem Kınıklı, Fırat Tan, Gamze Arın Bal, Ezgi Ünüvar Yüksel, Sibel Bozgeyik, Ferhat Öztürk

“…The findings regarding balance and weight distribution in this study could be valuable for clinicians in evaluating different kneeling abilities among individuals.…”
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