Completion of a standardizable competency-based research training program improves understanding and preparedness for both new and experienced clinical research professionals by Lucy Palmer, Sandra E. Morones, Heidi T. Jacobe, Rhonda Oilepo

“…Furthermore, faculty, clinicians, and trainees voluntarily completed this training program indicating utility across diverse groups. …”
Get full text

Disruptive mood dysregulation disorder, parental stress, and attachment styles by Marit Coldevin, Marit Coldevin, Astrid Brænden, Pål Zeiner, Pål Zeiner, Anne-Siri Øyen, Annika Melinder, Jan E. Stubberud

“…Our sample consisted of 218 children (6–12 years, Mage = 9.68 years) referred to child mental health outpatient clinics. Clinicians used a standardized semi-structured diagnostic interview to identify diagnoses. …”
Get full text

The Impact of Antibiotics on the Development of Colorectal Cancer – A Review of Current Insights and Directions for Future Research by Karol Zagórski, Mateusz Kozik, Nina Skalska-Dziobek, Weronika Małagocka, Karolina Chybowska, Maria Naruszewicz, Przemysław Cetnarowski

“…However, further research is needed to deepen our knowledge about the contribution of antibiotic use to CRC. Clinicians should carefully consider the benefits and risks of prescribing antibiotics, including possible long-term adverse events such as cancer onset. …”
Get full text

Rules for investigation of patients with asymptomatic elevation of serum aminotransferase activity by M. V. Mayevskaya, V. T. Ivashkin, Ye. N. German

“…Publication is intended for clinicians dealing with patients who have abnormal blood biochemical tests. …”
Get full text

Decoding substance use disorder severity from clinical notes using a large language model by Maria Mahbub, Gregory M. Dams, Sudarshan Srinivasan, Caitlin Rizy, Ioana Danciu, Jodie Trafton, Kathryn Knight

“…Existing diagnostic coding systems used by insurance providers, like the International Classification of Diseases (ICD-10), lack granularity for certain diagnoses, but American clinicians will add this granularity (as that found within the Diagnostic and Statistical Manual of Mental Disorders classification or DSM-5) as supplemental unstructured text in clinical notes. …”
Get full text

The diagnosis and treatment of 56 cases of breast hamartoma: a single-center analysis and a review of the literature by Hao Su, Caiyun Bai, Zhimin Fan, Di Wu, Fengjiang Qu

“…IntroductionTo analyze and summarize the clinical and pathological features of breast hamartoma to enhance clinicians’ awareness of this rare and benign lesion of the breast.MethodsWe retrospectively described the clinical data, imaging results, and pathological findings of 56 patients with breast hamartoma who underwent surgical treatment at the First Hospital of Jilin University between January 2005 and December 2020, and summarized the features. …”
Get full text

Targeted next-generation sequencing for antimicrobial resistance detection in ventilator-associated pneumonia by Yuting Li, Yanfang Jiang, Hao Liu, Yao Fu, Junying Lu, Hongyan Li, Lulu Sheng, Dejian Gu, Dong Zhang

“…Traditional microbial cultures limited by speed and sensitivity, are often unable to help clinicians make effective diagnosis and treatment. Therefore, there is an urgent need for a rapid and accurate test that can identify both pathogens and their antimicrobial resistance (AMR) to improve the prognosis of patients with VAP.Study designWe analyzed samples from ICU patients with suspected VAP using both microbial tests and targeted next-generation sequencing (tNGS), comparing the results of tNGS pathogen and AMR detection against microbial culture and antimicrobial susceptibility testing (AST).ResultsInvolving 199 patients with suspected VAP, tNGS showed a sensitivity rate of 98.98% for pathogen identification. …”
Get full text

Balancing the risks: continuous vs. interrupted anticoagulation during TAVI – what does the evidence say? by Ravi Patel, Emmanuel Kokori, Gbolahan Olatunji, Israel Charles Abraham, Adeola Akinboade, Emmanuel Ababio Agyemang, Adetola Babalola, Nicholas Aderinto

“…The findings show the importance of individualized anticoagulation strategies tailored to patient risk profiles. Clinicians should weigh the potential benefits of continuous anticoagulation against the risks, particularly in high-risk populations. …”
Get full text

Acute macular neuroretinopathy occurrence in a Behçet disease patient: a case report by Ayman Mabchour, Moncef Ould Hamou, Simon Correa, François Willermain, Nacima Kisma

“…Vigilance appears warranted during inflammatory episodes in BD, as they might contribute to such manifestations. Clinicians could consider BD as a potential differential diagnosis in patients presenting with features suggestive of AMN, and neurological involvement may merit cerebral imaging to exclude other causes. …”
Get full text

Multiple Electrophysiological Markers of Visual-Attentional Processing in a Novel Task Directed toward Clinical Use by Julie Bolduc-Teasdale, Pierre Jolicoeur, Michelle McKerral

“…This task could allow clinicians to track the recovery of the mechanisms involved in the deployment of visual-attentional processing, contributing to better diagnosis and treatment management for persons who suffer a brain injury.…”
Get full text

Comparative Study between Dermo, Pelite, and Seal-In X5 Liners: Effect on Patient’s Satisfaction and Perceived Problems by Sadeeq Ali, Noor Azuan Abu Osman, Nooranida Arifin, Hossein Gholizadeh, Nasrul Anwar Abd Razak, Wan Abu Bakar Wan Abas

“…These results showed that there is good indication to believe that Dermo liner might be a good choice for transtibial users and might help the clinicians and prosthetic practitioners in selection criteria of prosthetic liners.…”
Get full text

Clonorchis sinensis and Echinostoma hortense detected by endoscopy and molecular characterization: two case reports and update on diagnosis by Lijia Wen, Benhe Wang, Hui Zhang

“…Unfortunately, the non-specific clinical presentations of these two trematodes frequently mislead clinicians, resulting in overlooks or misdiagnoses, and consequently, inadequate treatment. …”
Get full text

Electrochemical sensors for the detection of immune checkpoint related proteins and their role in cancer companion diagnostics by Louise Barnaby, Andrew G. Watts, Pedro Estrela

“…Determining the chances of treatment success helps to inform clinicians to make the best treatment decisions for a particular patient. …”
Get full text

The validity of the renal Doppler resistivity index in renal allograft infections by Moataz Fatthy, Karim M. Soliman, Éva Csongrádi, Abd El Rahman Marzouk, Ahmed Fathy, Ahmed Fayed

“…There was a statistically significant difference in RRI in those with allograft infections, with the ROC curve for detection of infection utilizing RRI demonstrated an Area Under Curve 0.634 (p-value 0.015; cutoff value: 0.765; CI:0.527–0.742), with a specificity of 64.4% and a sensitivity of 68.8%.Conclusion Normal renal graft arterial resistivity index values, despite a renal allograft dysfunction, may be indicative of allograft infection, guiding clinicians’ decisions regarding kidney biopsy and facilitating further biopsy interpretations.…”
Get full text

Recurrent patellar dislocation: treatments and challenges by Fei Yang, Fei Yang, Changshun Chen, Changshun Chen, Rongjin Chen, Chenhui Yang, Hefang Xiao, Zhiwei Feng, Zhiwei Feng, Bin Geng, Yayi Xia

“…The goal of this narrative review is to offer clinicians a deeper understanding of RPD treatment, enhance clinical decision-making skills, and encourage personalized and efficient management of RPD treatment.…”
Get full text

The Prevalence of Restless Legs Syndrome in Patients with Migraine: A Systematic Review and Meta-Analysis by Hooman Ghasemi, Behnam Khaledi-Paveh, Alireza Abdi, Rostam Jalali, Nader Salari, Aliakbar Vaisi-Raygani, Masoud Mohammadi

“…This study highlights that RLS is high in patients with migraine, and therefore, the clinicians should be aware of its incidence and take preventive measures.…”
Get full text

Development of Novel Nomograms to Predict 5- and 7-Year Biochemical-Recurrence-Free Survival in High-Risk Prostate Cancer Patients After Carbon-Ion Radiotherapy and Androgen Depriv... by Takanobu Utsumi, Hiroyoshi Suzuki, Masaru Wakatsuki, Kana Kobayashi, Atsushi Okato, Mio Nakajima, Shuri Aoki, Taisuke Sumiya, Tomohiko Ichikawa, Koichiro Akakura, Hiroshi Tsuji, Shigeru Yamada, Hitoshi Ishikawa

“…These nomograms will enable adequate understanding and explanation of BCR-free survival to patients when clinicians use them.…”
Get full text

Aggressive Disease Course of Multiple Myeloma with Concomitant ALK-Negative Anaplastic Large Cell Lymphoma: A Case Report with an Unusual Presentation by Michela Staderini, Lara Mannelli, Elisabetta Antonioli, Benedetta Puccini, Valentina Berti, Francesco Mungai, Federica Vergoni, Valentina Carrai, Luigi Rigacci, Alberto Bosi

“…Simultaneous onset can be challenging for clinicians as both diseases may have an aggressive course requiring multiple treatments with increased risk of toxicity and complicated management.…”
Get full text

Impacts of the COVID-19 pandemic on treatment-seeking college students by Natalie R. Pottschmidt, Rebecca A. Janis, Brett E. Scofield, Alaina L. Cummins, Dever M. Carney, Katherine A. Davis, J. Ryan Kilcullen, Hongjun (Michael) Tan, Louis G. Castonguay, Benjamin D. Locke

“…Recommendations for clinicians, counseling centers, and institutions are highlighted based on this examination.…”
Get full text

Craniofacial Brown Tumor in Patients with Secondary Hyperparathyroidism to Chronic Renal Failure: Report of Two Cases in Cipto Mangunkusumo Hospital by Diani Kartini, Maria K. Siswiandari, Gunawan Wibisana, Erwin D. Yulian, Ahmad Kurnia, Sonar S. Panigoro, Azdi Z. Albar, Muchlis Ramli

“…The tumor regressed significantly within 2 weeks following the surgery, and we still observe tumor regression as well as reduction in PTH level. As clinicians, we should be alert to other possible causes of bony lesions. …”
Get full text