Targeted Therapy for Rheumatoid Arthritis in the New Era by WANG Jun, MENG Juan

“…This article aims to elaborate on the current research status and progress of these drugs, with the hope of providing insights for clinicians to better guide personalized treatment for RA patients.…”
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Pertussis Reinfection in an Adult: A Cause of Persistent Cough Not to Be Ignored by Theocharis Koufakis, Anastasia Paschala, Dimitrios Siapardanis

“…In this article, we report a case of pertussis reinfection 30 years after natural infection, which was complicated by pneumonia, and we discuss our diagnostic and therapeutic approach, aiming to raise clinicians’ degree of suspicion regarding pertussis diagnosis in adults. …”
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Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult by Max W. Jacobs, Joseph M. Rocco, Lisa K. Andersen, Thomas E. Robertson

“…The incidence of babesiosis is increasing and clinicians should have a high index of suspicion due to its diagnostic challenges and variable disease course, from asymptomatic infection to fulminant disease. …”
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Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain by Jason R. Andrews, Yoon Andrew Cho-Park, Judith Ferry, Jeremy S. Abramson, Gregory K. Robbins

“…In the HIV-infected patient with a mass lesion, a history of cutaneous Kaposi's sarcoma and prolonged immunosuppression should alert clinicians as to the possibility of KSHV-associated lymphoproliferative disorders, in order to establish a timely diagnosis.…”
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Advances in the Drugs Treatment of Psoriatic Arthritis by LU Chaofan, LENG Xiaomei

“…The objective of this study is to enhance clinicians' understanding of treatment strategies for PsA and provide more precise and effective treatment options for patients.…”
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Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases by Eric Mao, Aine Clements, Edward Feller

“…We report this small case series to alert clinicians to the diverse spectrum and diagnostic difficulties of this rare, potentially catastrophic association. …”
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Common Symptoms from an Uncommon Infection: Gastrointestinal Anisakiasis by Yuto Shimamura, Niroshan Muwanwella, Sujievvan Chandran, Gabor Kandel, Norman Marcon

“…Clinicians can be forgiven for thinking of anisakiasis as a rare condition low in the differential diagnosis of abdominal pain. …”
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The First case of Locally Acquired Tick-Borne Babesia Microti Infection in Canada by Jared MP Bullard, Arshad N Ahsanuddin, Anamarija M Perry, L Robbin Lindsay, Mahmood Iranpour, Antonia Dibernardo, Paul G Van Caeseele

“…The expanding territory of the blacklegged tick increases the relevance of this emerging infection. Clinicians, laboratory medical practitioners and public health officials should be aware of B microti as a potential locally acquired infection in Canada.…”
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Thrombolytic therapy and nursing management of a patient with hemichorea-hemiballismus caused by acute cerebral infarction (1例急性脑梗死致偏侧舞蹈症的溶栓治疗和护理体会)... by XIAO Zhouhua (肖周华), YAO Weiling (姚卫灵), WANG Xin (王欣)

“…It is necessary to enhance the vigilance of clinicians. Based on the intravenous thrombolytic therapy, a comprehensive nursing plan including vital signs monitoring, safe protection, and prevention of fall and disease recurrence should be carried out to improve the curative effect and prognosis of such patients. …”
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Patient with Crouzon Syndrome Treated with Modified Le Fort III Osteotomy without Previous Orthodontic Treatment: Case Report and a Review of the Literature by Farnoosh Mohammadi, Afrooz Javanmard, Hamid Mojtahedi

“…Crouzon syndrome is the most common type of craniofacial dysostosis anomaly which presents a great challenge for clinicians since birth. Multiple synostoses in the sutures of the cranial base in this syndrome result in the hypoplasia of the midface, shallow orbits, a short nasal dorsum, maxillary hypoplasia, and, in severe cases, obstruction of the upper airways. …”
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Kikuchi–Fujimoto disease presenting as pyrexia of unknown origin by Prasanta Padhan, Krishna Prasad Tripathy, Saroj Ranjan Sahoo, Debasish Maikup, Nachiketa Mahapatra

“…The patient was found to have multiple abdominal and cervical lymph nodes on imaging, biopsy and immunohistochemistry revealed histiocytic necrotizing lymphadenitis, which confirmed the diagnosis of KFD. Although rare, clinicians should be aware of KFD condition, as early recognition of the disease will minimize potentially harmful and unnecessary evaluation and treatments.…”
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An Unusual Benign Cause of an Alarming Finding on Chest-X ray: A Case Report of Widened Mediastinum due to Rare Congenital Abnormality (Azygos Vein Continuation of Inferior Vena Ca... by Michael Hanna, Ghada Elshimy, Medhat Ismail, Mourad Ismail

“…This is considered as a rare benign cause of wide mediastinum. Clinicians must be aware of the presence of such a benign cause when dealing with acute wide mediastinum.…”
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Giant Hypopharyngeal Fibrovascular Polyp: A Case Report and Review of the Relevant Literature by Suheyl Haytoglu, Birgul Tuhanioglu, Abdurrahman Bozkurttan, Osman Kursat Arikan

“…This case highlights the need for clinicians to be aware of this rare entity and to develop the best approach to patient management.…”
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Diabetic Mastopathy: An Uncommon Complication of Diabetes Mellitus by R. X. Kirby, D. I. Mitchell, N. P. Williams, D. A. Cornwall, S. O. Cawich

“…Histopathologic evaluation revealed classic features of DMP: parenchymal fibrosis; keloid-like hyalinization of interlobular stroma; adipose tissue entrapment; lobular compression; dense chronic inflammatory cell infiltration; and lymphoid follicle formation. Conclusion. Clinicians should be aware of DMP as a differential for breast disease in women with uncontrolled diabetes.…”
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Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease by Melissa S. Putman, Alexandra Haagensen, Isabel Neuringer, Leonard Sicilian

“…Because adherence to a gluten-free diet may improve BMD in patients with celiac disease, this could have important implications for treatment. Clinicians should consider screening for celiac disease in patients with CF who have low BMD, worsening BMD in the absence of other risk factors, and/or difficult to treat vitamin D deficiency.…”
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Central Hypogonadotropic Hypogonadism: Genetic Complexity of a Complex Disease by Marco Marino, Valeria Moriondo, Eleonora Vighi, Elisa Pignatti, Manuela Simoni

“…The aim of this review is to summarize the current knowledge on genetic background of CHH, organizing the large amount of data present in the literature in a clear and concise manner, to produce a useful guide available for researchers and clinicians.…”
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Paroxysmal Cold Hemoglobinuria in an Adult with Respiratory Syncytial Virus by Ryan Leibrandt, Kenneth Angelino, Monique Vizel-Schwartz, Ilan Shapira

“…To facilitate identification of this rare entity by clinicians, we include a discussion about the pathophysiology, diagnosis, and treatment of PCH.…”
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Sleep in Chronic Obstructive Pulmonary Disease: Evidence Gaps and Challenges by Rachel Jen, Yanru Li, Robert L. Owens, Atul Malhotra

“…This review aims to draw attention to the problem of sleep in COPD, to encourage clinicians to ask their patients about symptoms, and to stimulate further research in this area given the large burden of the disease.…”
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Predicting, Treating and Preventing Postoperative Recurrence of Crohn’s Disease: The State of the Field by Anna M Borowiec, Richard N Fedorak

“…The goal of the present article is to provide a coherent summary of previous and new research to guide clinicians in managing the challenging and complex problem of postoperative Crohn’s disease recurrence.…”
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Review and Clinical Perspectives for the Use of Infliximab in Ulcerative Colitis by Remo Panaccione, Richard N Fedorak, Guy Aumais, Edmond-Jean Bernard, Charles N Bernstein, Alain Bitton, Ken Croitoru, Levinus A Dieleman, Robert Enns, Brian G Feagan, Denis Franchimont, Gordon R Greenberg, Anne-Marie Griffiths, John K Marshall, Pierre Pare, Sunil Patel, Robert Penner, Craig Render, Ernest Seidman, A Hillary Steinhart

“…A review of the literature is followed by practical recommendations regarding infliximab that address the needs of clinicians and UC patients. Where there is a lack of evidence-based information, the expert panel provides its combined opinion derived from the members’ clinical experiences.…”
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