Melanonychia by Julie Jefferson, Phoebe Rich

“…Melanonychia, or melanin-derived brown-to-black nail pigmentation, is a diagnostic challenge for clinicians. The most serious disease of the nail unit, melanoma, primarily presents with melanonychia. …”
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The 24/7 approach to improving outcomes for children affected by chronic trauma and dissociation by Richard Cross

“…Over time, various clinicians have theorised about psychological and emotional distress observed in children, but it is only in relatively recent times that they began to attribute some of the causes to early childhood experiences of neglect and trauma. …”

Physical Activity Modulates Common Neuroplasticity Substrates in Major Depressive and Bipolar Disorder by Cristy Phillips

“…Accordingly, the aims of this review are to (1) explicate key modulators, processes, and interactions that impinge upon multiple susceptibility points to effectuate neuroplasticity deficits in MDs; (2) explore the putative mechanisms by which PA mitigates these features; (3) review protocols used to induce the positive effects of PA in MDs; and (4) highlight implications for clinicians and researchers.…”
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Perampanel-associated Psychiatric Problems by Anil Kakunje, Shivanand Pai, S. Raghavendra

“…The condition warranted a psychiatry referral, and the problems subsided after stopping perampanel. Clinicians need to be vigilant about perampanel-associated behavioral and psychiatric problems which can become a serious clinical concern.…”
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Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis by Alisha Puri, Anita M. Lloyd, Aminu K. Bello, Marcello Tonelli, Sandra M. Campbell, Karthik Tennankore, Sara N. Davison, Stephanie Thompson

“…The evidence does not support the use of clinicians’ subjective impression to identify frailty. …”
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The Single Leg Squat Test: A “Top-Down” or “Bottom-Up” Functional Performance Test? by Lindsay A Carroll, Benjamin R Kivlan, RobRoy L Martin, Amy L Phelps, Christopher R Carcia

“…These findings suggest that clinicians may continue using the SLST to assess neuromuscular performance of the trunk, hip, and knee without ankle dorsiflexion ROM or foot posture contributing to results…”
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Determining timeframes to death for imminently dying patients: a retrospective cohort study by Tricia O’Connor, Wai-Man Liu, Juliane Samara, Joanne Lewis, Karen Strickland, Catherine Paterson

“…Abstract Background Clinicians are frequently asked ‘how long’ questions at end-of-life by patients and those important to them, yet predicting timeframes to death remains uncertain, even in the last weeks and days of life. …”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…Then, this candidate list of strategies was presented to an expert stakeholder panel including clinicians and clinical operations specialists. Through a modified Delphi process, the list was narrowed to select the most promising strategies to incorporate in an intervention to improve cognitive evaluations in primary care. …”
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Engaging stakeholders in the co-development of programs or interventions using Intervention Mapping: A scoping review. by Umair Majid, Claire Kim, Albina Cako, Anna R Gagliardi

“…Those that did (71.7%) often involved a combination of patients, clinicians, and community organizations. However, less than half (48.8%) described how they were engaged. …”
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Anatomic Variations Important for Dental Implantation in the Mandible—A Systematic Review by Zlata Rajkovic Pavlovic, Milos Stepovic, Marija Bubalo, Ivana Zivanovic Macuzic, Maja Vulovic, Nevena Folic, Jovana Milosavljevic, Valentina Opancina, Dobrivoje Stojadinovic

“…The results of this study can aid in choosing appropriate measurement points and give the gross picture, for clinicians, in therapy planning, considering all the landmarks of significance in the mandible.…”
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Reliability and Validity of the ActivForce Digital Dynamometer in Assessing Shoulder Muscle Force across Different User Experience Levels by Christos Karagiannopoulos, Sean Griech, Brian Leggin

“…Its low-cost and electronic accessibility features may promote better compliance for clinicians using dynamometry to objectively assess and store muscle force data in a cost-effective manner…”
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Evaluation of Noninvasive Tools for Predicting Esophageal Varices in Patients With Cirrhosis at Tygerberg Hospital, Cape Town by Lawrence Kwape, Shiraaz Gabriel, Ahmad Abdelsalem, Penelope Rose, Lefika Bathobakae, Dale Peterson, Desiree Moodley, Mohammed Parker, Saadiq Moolla, Arifa Parker, Keatlaretse Siamisang, Christoffel Van Rensburg, Ernst Fredericks

“…These prediction tools can help clinicians avoid unnecessary endoscopic procedures in patients with compensated cirrhosis, especially in developing countries with limited resources such as South Africa.…”
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Bilateral Tensor Fasciae Suralis Muscles in a Cadaver with Unilateral Accessory Flexor Digitorum Longus Muscle by Logan S. W. Bale, Sean O. Herrin

“…Muscle variants are routinely encountered in the dissection laboratory and in clinical practice and therefore anatomists and clinicians need to be aware of their existence. Here we describe two different accessory muscles identified while performing educational dissection of a 51-year-old male cadaver. …”
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Cone Beam Computed Tomographic Evaluation and Diagnosis of Mandibular First Molar with 6 Canals by Shiraz Pasha, Bathula Vimala Chaitanya, Kusum Valli Somisetty

“…However, in everyday endodontic practice, clinicians have to treat teeth with atypical configurations for root canal treatment to be successful. …”
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Iatrogenic intracranial hypotension complicated to dural venous sinus thrombosis and lobar hemorrhage: A case report by Hidayatullah Hamidi, MD, Mohammad Iqbal Haqyar, MD

“…The diagnosis was made via cerebral magnetic resonance (MR) imaging, and the patient was treated medically.This case study aimed to assist clinicians in considering the possible complications of intracranial hypotension when evaluating patients with a recent history of spinal procedures, leading to early diagnosis and treatment to prevent devastating consequences.…”
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Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture by Zartaj Ahmed, Ramesh K. Ramanathan, Sunil Ram, James Newell, Maqbool Halepota

“…We report a 63-year-old male patient, who responded well to treatment for PCNSL but relapsed two and half years later with a lumbosacral nodule at the site of a previous lumbar puncture due to microscopic tumor seeding. Clinicians treating patients with PCNSL must remain alert to the possibility of extracranial solitary relapse even after the resolution of initial disease because prompt treatment can result in a good outcome.…”
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Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis by Guglielmo Manenti, Simone Altobelli, Marco Nezzo, Marco Antonicoli, Erald Vasili, Luca Neroni, Roberto Floris, Giovanni Simonetti

“…While other imaging techniques such as computed tomography lack sensitivity and specificity, magnetic resonance performed with morphological and functional sequences offers clinicians the possibility to early identify the stage of the disease and the emergence of an immune reconstitution inflammatory syndrome after natalizumab blood removal plasmapheresis.…”
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Bile Salt Enterolith: An Unusual Etiology Mimicking Gallstone Ileus by Dana Ferrari-Light, Ariel Shuchleib, Joel Ricci-Gorbea

“…A 4.5 cm enterolith removed from the distal jejunum was found to contain 100% bile salts, consistent with a primary enterolith. Clinicians should retain a high index of suspicion for enteroliths as a cause of small bowel obstruction, especially if multiple risk factors for enterolith formation are present.…”
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Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen by Suyash Dahal, Sumit Dahal, Dipesh K. C. Ghimire, Ebad Ur Rahman, Eliza Sharma

“…With the patient refusing splenectomy, he was managed conservatively. Clinicians need to be aware of this rare complication of sickle cell variants.…”
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Opportunities for collaboration: the synergy between antimicrobial and diagnostic stewardship in pediatrics by Brandy M. Hoyt, Kevin Messacar, Anna C. Sick-Samuels, Preeti Jaggi, Stacey L. Hamilton, Sarah Janelle, Sarah K. Parker

“…Advancement of antimicrobial stewardship (AS) programs requires partnership with clinicians, quality assurance teams, and laboratorians. …”
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