Endo-Perio Lesion and Uncontrolled Diabetes by Sara Dhoum, Kaoutar Laslami, Fatimazahraa Rouggani, Amal El Ouazzani, Mouna Jabri

“…This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. …”
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Delay in Diagnosis of Cerebral Venous and Sinus Thrombosis: Successful Use of Mechanical Thrombectomy and Thrombolysis by Christopher T. Shah, Jason J. Rizqallah, Oladoyin Oluwole, Aleksandrs Kalnins, John N. Sheagren

“…Our case highlights the need for clinicians to include CVST in the initial differential diagnosis of patients in order to prevent delays and poor outcomes.…”
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Docetaxel-Induced Stevens-Johnson Syndrome in a Patient with Metastatic Prostate Adenocarcinoma by Osama Diab, Dan Mcentire, Thamer Kassim, Ali Nayfeh, Abdel Rahman Dajani, Mitchell Kerfeld, Jonathon Campbell, Adbullah Alsuwaidan, Mahmoud Abu Hazeem, Maryam Gbadamosi-Akindele

“…This medication is not classically associated with the development of SJS but in our case, along with a number of other case reports, and a single phase II clinical trial, an association was recognized. We encourage clinicians who employ the use of this medication to be aware of this relationship.…”
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Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction by Anthony Elias, Kirsty Wark, Dana Slape, David Cook, Kenneth Lee, Genevieve Mckew

“…His treatment was complicated by a severe exacerbation of his cutaneous eruption following the commencement of penicillin, likely secondary to a Jarisch–Herxheimer reaction, an entity often overlooked by clinicians managing syphilis.…”
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Extensive Bilateral Intracranial Calcifications: A Case of Iatrogenic Hypoparathyroidism by Vaso Zisimopoulou, Anna Siatouni, Grigorios Tsoukalos, Antonios Tavernarakis, Stylianos Gatzonis

“…Detection of brain calcinosis in patients who had total thyroidectomy can motivate clinicians in further investigation of possible hypoparathyroidism with measurement of calcium and phosphorus serum levels.…”
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Endoscopic vacuum therapy in the upper gastrointestinal tract by Kirsten Boonstra, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Yasmijn J. van Herwaarden, Wietse J. Eshuis, Wietse J. Eshuis, Roos E. Pouw, Roos E. Pouw, Roos E. Pouw

“…We provide an overview, including mechanism, indications, types of EVT devices and complications, guiding clinicians in decision-making. Common challenges in EVT are highlighted, facilitating adequate implementation of EVT and helping to avoid common mistakes in daily practice.…”
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Malignant Perivascular Epithelioid Cell Tumor of the Esophagus by Matteo Fassan, Mauro Cassaro, Massimo Vecchiato, Roberto Clemente, Gianmaria Pennelli, Stefano Merigliano, Giuseppe Altavilla

“…Although PEComas arising within the gastrointestinal tract are exceptional findings, clinicians should not exclude this class of tumors in the diagnostic investigation of a bulky lesion of the esophageal wall.…”
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Intra-Articular Osteoid Osteoma Mimicking Juvenile Arthritis by Sidi Yaya Traore, Dana Ioana Dumitriu, Pierre-Louis Docquier

“…Diagnosis of osteoid osteoma was finally given by CT-scan and appropriate treatment by radiofrequency ablation or surgical ablation was performed. Clinicians and radiologists should be aware of the potentially confusing clinical and imaging findings associated with intra-articular osteoid osteoma.…”
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Response of Immunotherapy to Tumour-TICLs Interactions: A Travelling Wave Analysis by Joseph Malinzi, Precious Sibanda, Hermane Mambili-Mamboundou

“…Mathematical modelling can nevertheless point out to clinicians tumour invasion properties that should be targeted to mitigate these cancers. …”
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Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia by Terry C Wuerz, Eric J Bow, Matthew D Seftel

“…This is highlighted in the present article, which describes a case of brain abscess due to Nocardia species that developed while receiving dapsone as an alternative for prophylaxis against Pneumocystis jirovecii pneumonia in a highly immune-suppressed patient. Clinicians should be cognizant of these issues when prescribing alternative agents.…”
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Preventing unrestricted and unmonitored AI experimentation in healthcare through transparency and accountability by Donnella S. Comeau, Danielle S. Bitterman, Leo Anthony Celi

“…To safeguard patients, especially the vulnerable, clinicians must advocate for patient-centered education, ethical practices, and robust oversight to prevent harm.…”
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Subdural Empyema Complicating Bacterial Meningitis: A Challenging Diagnosis in a Patient with Polysubstance Abuse by Melissa Dakkak, William Russell Cullinane, Virin Rajiv Neil Ramoutar

“…Subdural empyema (SDE) and cerebrovascular accident (CVA) are uncommon life-threatening complications of bacterial meningitis, which require urgent neurosurgical intervention to prevent adverse outcomes. Clinicians must be vigilant of the onset of focal neurologic deficits or seizure activity to establish the diagnosis of SDE. …”
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Periodontal Indices as Predictors of Cognitive Decline: Insights from the PerioMind Colombia Cohort by Catalina Arévalo-Caro, Diego López, Jose Antonio Sánchez Milán, Cristina Lorca, María Mulet, Humberto Arboleda, Sergio Losada Amaya, Aida Serra, Xavier Gallart-Palau

“…<b>Methods</b>: To address this gap and develop novel tools to help clinicians identify individuals at risk of cognitive decline, we established the PerioMind Colombia Cohort, comprising elderly Colombian subjects who underwent comprehensive neurocognitive and periodontal evaluations. …”
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Adapting to ulcerative colitis to try to live a ‘normal’ life: a qualitative study of patients’ experiences in the Midlands region of England by Rachel Cooney, Christel McMullan, Dmitri Nepogodiev, Laura Magill, Thomas D Pinkney, Jonathan M Mathers, Laura L Jones, Shri Pathmakanthan

“…Awareness of this may help clinicians and researchers to understand patients’ views on the role of medical and other therapies. …”
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What are the respiratory health research priorities in Alberta, Canada? A stakeholder consultation by Michael K Stickland, Sachin R Pendharkar, Jananee Rasiah, Joanna E MacLean, Heather Sharpe, Lisa Cerato, Darlene Derech, Lisa Guirguis, Kathleen Hayward, Tara Lohmann, Elizabeth Manafo, Janice Paskey, Mark Rimkus, Syeda Kinza Rizvi, Gerry Robinson, Brent Seefried, Zeeyaan Somani, Mindy Tindall, Harissios Vliagoftis, Kathy Hayward

“…Stakeholders were surveyed again to prioritise the remaining 83 questions and they were reviewed by the project’s Steering Committee (clinicians and patients). At the inperson workshop, the Steering Committee identified 17 research topics as priority areas for respiratory and sleep research in Alberta.Conclusion A stakeholder-led research prioritisation process identified optimal clinical management/follow-up, equitable access to services, and management of social, psychological and mental health issues related to respiratory/sleep health as priority research areas.…”
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Enhancing cardiac assessments: accurate and efficient prediction of quantitative fractional flow reserve by Arshia Eskandari, Sara Malek, Alireza Jabbari, Kian Javari, Nima Rahmati, Behrad Nikbakhtian, Bahram Mohebbi, Seyed Ehsan Parhizgar, Mona Alimohammadi

“…The proposed methodology has the potential to significantly assist clinicians with diagnosis.…”
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Mathematical methods in systems biology by Eugene Kashdan, Dominique Duncan, Andrew Parnell, Heinz Schättler

“…As stated in the workshop goals, we managed to attract a good mix of mathematicians and statisticians working on biological and medical applications with biologists and clinicians interested in presentingtheir challenging problems and looking to find mathematical and statistical tools for their solutions.For more information please click the “Full Text” above.…”
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Sulphasalazine-Induced Pseudomembranous Colitis by Hugh J Freeman, Urs P Steinbrecher, WC Peter Kwan, Stephanie Ensworth

“…Despite the frequent use of sulphasalazine in the management of inflammatory bowel disease, this complication has been apparently rare. Clinicians should be wary of the onset of diarrhea in patients receiving sulphasalazine, whether for inflammatory bowel disease or other conditions.…”
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Eyelid edema in relapsing polychondritis by Anshul Goel, Arun Gogna

“…The pleomorphic nature, the wide spectrum of clinical features and insidious onset of the disease makes the diagnosis of RP a challenge for clinicians. Eyelid edema is a recognized manifestation of this disease frequently in association with inflammation in other parts of eyes. …”
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Pneumococcal Meningitis Complicated by Cerebral Vasculitis, Abscess, Hydrocephalus, and Hearing Loss by Abdul Razzakh Poil, Adila Shaukat, Devendra Kumar

“…Here, we report a case of a 48-year-old male who developed postinfectious vasculitis, abscess, hydrocephalus, and hearing loss after S. pneumoniae meningitis. Clinicians ought to be aware of the possible adverse outcomes of S. pneumoniae meningitis and the limitations of current treatment options.…”
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