Cancer Vaccine by Fusions of Dendritic and Cancer Cells by Shigeo Koido, Eiichi Hara, Sadamu Homma, Yoshihisa Namiki, Toshifumi Ohkusa, Jianlin Gong, Hisao Tajiri

“…In the human studies, T cells stimulated by DC/tumor fusion cells are effective in lysis of tumor cells that are used as the fusion partner. In the clinical trials, clinical and immunological responses were observed in patients with advanced stage of malignant tumors after being vaccinated with DC/tumor fusion cells, although the antitumor effect is not as vigorous as in the animal tumor models. …”
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Practice Variations in the Use of Novel Oral Anticoagulants for Nonvalvular Atrial Fibrillation-Related Stroke among Stroke Neurologists in Saudi Arabia by Mohammed H. Alanazy, Taim Muayqil

“…Clinical trials have demonstrated that novel oral anticoagulants (NOACs) are noninferior to warfarin in preventing nonvalvular atrial fibrillation- (nvAF-) related stroke and systemic embolism. …”
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NoFumo+: Mobile Health App to Quit Smoking Using Cognitive-Behavioral Therapy by Patricia García-Pazo, Joana Fornés-Vives, Albert Sesé Abad

“…Finally, investigation project registered in ClinicalTrials.gov with reference to this trial is registered with NCT045402004.…”
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Sedentary Behaviour and Physical Activity of People with Stroke in Rehabilitation Hospitals by Anna Sjöholm, Monica Skarin, Leonid Churilov, Michael Nilsson, Julie Bernhardt, Thomas Lindén

“…Interventions to promote reduced sedentary time could help improve outcome and these should be tested in clinical trials.…”
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Quality of Life in Wilson’s Disease: A Systematic Literature Review by Chakrapani Balijepalli, Kevin Yan, Lakshmi Gullapalli, Stephane Barakat, Helene Chevrou-Severac, Eric Druyts

“…**Methods:** To address this gap in the literature, we conducted a systematic literature review in MEDLINE and EMBASE to identify observational studies and clinical trials reporting QOL outcomes among people living with WD. …”
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Early disease detection expert system development: primary machining software applications and dependences by A. S. Serobabov, E. V. Chebanenko, L. A. Denisova, T. S. Krolevets

“…The article observes descriptive statistics tools for the biomedical information processing, clinical trials data on the nonalcoholic fatty liver disease (NAFLD). …”
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Recent Advances and Perspectives on the Use of Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Chronic Kidney Disease: A Review by Kisho Miyasako, Yujiro Maeoka, Takao Masaki

“…Here, we discuss recent findings and the roles of MRAs in the management of hypertension and CKD, with a focus on the evidence obtained from fundamental research and major clinical trials.…”
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Comparing robot-assisted and conventional surgery in knee replacement: A meta-analysis of surgical-site wound complications and recovery outcomes by Hu Liang, Yangquan Hao, Wenxing Yu

“…A total of 590 publications were explored, and 16 related randomized clinical trials (RCTs) were analyzed in depth to unveil the role of robots in knee replacement surgery. …”
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Update on Remdesivir in the Treatment of Novel Coronavirus Pneumonia by Huang Feng, K. Vijaya Lakshmi, Chin Tat Ng, Murthy Sasikumar, Masita Arip, Masriana Hassan, Voon Kin Chin, Mogana Rajagopal, Omotayo Fatokun, N. Parvathi, Malarvili Selvaraja

“…More importantly, the outcome of current clinical trials of Remdesivir alone and when combined with other drugs for COVID-19 management was analyzed, and the limitations and clinical significance of each clinical trial were evaluated. …”
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Brain Complete Response to Cabozantinib prior to Radiation Therapy in Metastatic Renal Cell Carcinoma by An Uche, Chad Sila, Tad Tanoura, James Yeh, Neil Bhowmick, Edwin Posadas, Robert Figlin, Jun Gong

“…Its activity in mRCC patients with brain metastases (BMs) has been largely underreported in prospective clinical trials. We present the unique case of a heavily pretreated mRCC patient with BMs who achieved a brain complete response to cabozantinib prior to receiving radiation therapy. …”
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The impact of quantitative platform on candidacy for bronchoscopic lung volume reduction: a multi-center retrospective cohort study by Max Wayne, Suchitra Pilli, Hee Jae Choi, Nathaniel Moulton, Praveen Chenna, Allen Cole Burks, Alexander Chen

“…The recommendation to proceed with BLVR was based on a prespecified algorithm using criteria established in clinical trials for each quantitative platform, respectively. …”
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Acute Liver Failure Caused by Amanita phalloides Poisoning by Luca Santi, Caterina Maggioli, Marianna Mastroroberto, Manuel Tufoni, Lucia Napoli, Paolo Caraceni

“…The clinical efficacy of any modality of treatment is difficult to demonstrate since randomized, controlled clinical trials have not been reported. The use of extracorporeal liver assist devices as well as auxiliary liver transplantation may represent additional therapeutic options.…”
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Developing hyperpolarized metabolic contrast agents at high field dDNP for large animal research by Ditte B. Christensen, Ingeborg S. Skre, Jan Henrik Ardenkjær-Larsen, Magnus Karlsson, Mathilde H. Lerche

“…While several metabolic substrates have been investigated at lower field dDNP and tested as HMCAs in rodents, 13C-labeled pyruvate remains the most studied HMCA and is currently the only one actively used in clinical trials due to its favorable biological and physical properties. …”
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COLORATION AND DISCOLORATION OF OLVEOLAR BONE AND TOOTH ENAMEL CAUSED BY MEDICATION by Giurgiu Cristian Levente, George Morarasu, Nicolae Baranov, Pogăcian-Maier Alexandra-Camelia, Radu-Mircea Sireteanu-Cucui, Cristina Pipa, Alina Monica Miftode, Alina Stefanache

“…Keywords related to tooth discoloration and medications were used to identify relevant studies, including clinical trials and case reports published between 1990 and 2023. …”
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The modern use of hydroxyurea for children with sickle cell anemia by Charles T. Quinn, Russell E. Ware

“…From initial small proof-of-principle studies to multi-center Phase 3 controlled clinical trials and then numerous open-label studies, the consistent benefits of once-daily oral hydroxyurea have been demonstrated across the lifespan. …”
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A meta-analysis of the effectiveness and side effects of hip arthroscopy and open surgical dislocation in the management of femoroacetabular impingement by Chenlie Ni, Haiqing Lin, Haibo Yin

“…The purpose of this meta-analysis is to assess the effectiveness and safety of hip arthroscopy compared to open surgical dislocation for the treatment of femoroacetabular impingement (FAI), based on clinical trials that have been published. Methods A comprehensive literature search was conducted through PUBMED, EMBASE, and the Cochrane Central Register of Controlled Trials for studies evaluating coxoscopy and open surgical dislocation as treatment modalities for femoroacetabular impingement syndrome (FAI). …”
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Use of complementary and alternative medicine in head and neck cancer: Salutary or noxious by Nikunj Maniyar, Sachin C. Sarode, Shruti Thakkar, Gargi S. Sarode

“…Alternatively, patients increasingly explore several other complementary and alternative medicine (CAM) therapies. Though clinical trials of certain CAM modalities have shown effectiveness in managing symptoms and risk behaviours allied with HNC and its treatment, evidence also suggests a need for heed. …”
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Immunotherapy in colorectal cancer: Statuses and strategies by Yuan Li, Zewei Cheng, Shengli Li, Jiwei Zhang

“…This review endeavors to offer a comprehensive overview of current strategies in CRC immunotherapy, critically analyze existing literature, underscore anticipated outcomes from ongoing clinical trials, and deliberate on the challenges and impediments encountered within the field of immunotherapy.…”
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Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy by Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem

“…Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU. The clinical trial is registered with NCT04018326 (trial registration: ClinicalTrials.gov Identifier: NCT04018326, 10th of July 2019 “Retrospectively registered”).…”
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Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

“…Islet transplantation to portal vein provides an approach to compensate for loss of insulin producing cells. Clinical trials demonstrated that even partial islet graft function reduces severe hypoglycemic events in patients. …”
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