Advanced progress in the genetic modification of the oncolytic HSV-1 virus by Mi Zhou, Mi Zhou, Mi Zhou, Zhenyu Shen, Zhenyu Shen, Zhenyu Shen

“…Finally, we discuss limitations associated with oncolytic virotherapy at the conclusion of this review. As more clinical trials explore newly engineered therapies, they are likely to yield breakthroughs and promote broader adoption for cancer treatment.…”
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An 8-week physical exercise intervention for e'athletes improves physical performance rather than short-term esports performance parameters - a randomized controlled trial by Felix Wachholz, Nicole Gamper, Martin Schnitzer

“…Participants reported that engaging in physical activity within the context of esports and gaming positively contributed to their overall well-being. Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT06264375).…”
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TraxVBF: A hybrid transformer-xLSTM framework for EMG signal processing and assistive technology development in rehabilitation by Seyyed Ali Zendehbad, Athena Sharifi Razavi, Marzieh Allami Sanjani, Zahra Sedaghat, Saleh Lashkari

“…These results indicate that TraxVBF may be a useful tool to improve motor learning and rehabilitation, and longer term clinical trials and multi-sensory biofeedback are needed.…”
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Cost-Utility Analysis of Add-on Cannabidiol vs Usual Care Alone for the Treatment of Seizures in Patients With Treatment-Resistant Lennox-Gastaut Syndrome or Dravet Syndrome in the... by Jamshaed Siddiqui, Sally Bowditch

“…Population characteristics, clinical inputs, and utility values were sourced from CBD clinical trials and quality-of-life studies. Drug acquisition, disease management, adverse events, and societal costs from published literature were included. …”
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ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

“…ZBiotics is recommended for clinical trials as a separate candidate or as an adjuvant to the conventional T2DM therapy.…”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant by Pritam Sarkar, Tasfiya Rufaidah Ahnaf, Razina Rouf, Jamil Ahmad Shilpi, Shaikh Jamal Uddin

“…Despite numerous studies demonstrating various pharmacological advantages of this plant and its constituents, the number of clinical trials conducted on humans remains significantly limited.…”
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The Clinical Effect of Oral Vitamin D2 Supplementation on Psoriasis: A Double-Blind, Randomized, Placebo-Controlled Study by Wareeporn Disphanurat, Wongsiya Viarasilpa, Panlop Chakkavittumrong, Padcha Pongcharoen

“…This trial is registered with Thai Clinical Trials Registry TCTR20180613001.…”
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Transcranial direct current stimulation combined with physical exercise in rotator cuff tendinopathy: a protocol for a blinded randomised controlled trial by César Augusto Medeiros Silva, Clécio Gabriel de Souza, Vinicius Batista Lima, Hannely Beatriz Menezes Cosme, Romário Nóbrega Santos Fonseca, Fuad Ahmad Hazime, Rodrigo Scattone da Silva, Rodrigo Pegado de Abreu Freitas

“…The results will be published later in peer-reviewed journals and scientific events.Trial registration number The Brazilian Registry of Clinical Trials (RBR-59xmv6s); Results.…”
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Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis by Muhammad Osama, Muhammad Haris Khan, Safeena Khan, Amna Hussain, Ammara Tahir, Mehran Ullah, Abdullah Afridi, Ubaid Ullah, Wajeeh Ur Rehman

“…Methods: We performed a comprehensive literature search on PubMed, the Cochrane Database, and ClinicalTrials.gov. The primary outcomes were progression-free survival (PFS) and minimal residual disease (MRD) status. …”
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Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location by Christopher Wills, Katie Watts, Amy Houseman, Timothy S. Maughan, David Fisher, Nada A. Al-Tassan, Richard S. Houlston, Valentina Escott-Price, Jeremy P. Cheadle

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AGENTS USED FOR ENAMEL REMINERALISATION AND REDUCING DENTIN HYPERSENSITIVITY: A COMPREHENSIVE REVIEW by N.V. Yanko

“…Efficacy of different kinds of lasers alone or in combination with a remineralisation agent has been confirmed mostly in vitro studies, therefore, there is a lack of clinical trials to prove their benefit. In latter studies, dentin sealants and desensitisers occluded dentin tubules were superior to conventional fluorides and synthetic nanohydroxyapatites. …”
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Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments by Belluzzi L, Martinelli G, Medici B, Farina A, Martinelli E, Canino F, Caggia F, Molinaro A, Barbolini M, Tamburrano F, Moscetti L, Piacentini F, Dominici M, Omarini C

“…A literature search was performed between January and June 2024, considering papers, clinical trials, case reports, case series, meta-analyses, and systematic reviews published from January 2014 to June 2024. …”
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Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite by Débora Apª O. Modena, Caroline Nogueira da Silva, Talita C. P. Delinocente, Tatiane Bianca de Araújo, Tania Maria de Carvalho, Clovis Grecco, Renata Gomes Moreira, Gisele Campos, José Ricardo de Souza, Renata Michelini Guidi

“…This trial is registered with ClinicalTrials: NCT03275259.…”
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Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review by Roberto Gazzeri, Jacopo Mosca, Felice Occhigrossi, Marco Mercieri, Marcelo Galarza, Matteo Luigi Giuseppe Leoni

“…Innovations in neurostimulation, including closed-loop systems and personalized treatment strategies have the potential to further optimize outcomes. Rigorous clinical trials are needed to consolidate the role of SCS as a cornerstone therapy for the management of RAP.…”
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Effects of falls prevention interventions on falls outcomes for hospitalised adults: protocol for a systematic review with meta-analysis by Anne-Marie Hill, Meg E Morris, David L Carey, Susan C Slade

“…Inclusion criteria: randomised controlled trials, quasi-randomised trials or controlled clinical trials that evaluate falls prevention interventions for use by hospitalised adults or employees. …”
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Process evaluation of a cross-sectoral, coordinated follow-up care of stroke patients: a qualitative study by Theresa Schrage, Claudia Glissmann, Götz Thomalla, David Leander Rimmele, Holger Schmidt, Michael Rosenkranz, Stefan Boskamp, Martin Härter, Levente Kriston

“…Trial registration The trial is registered at ClinicalTrials.gov (NCT04159324), registration date 12/11/19.…”
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Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers by Xiao-Ling Qin, Qiang Huang, Han-Wen Zhang, Yi Zeng, Xian-Shu Lin, Xiao-Yuan Fan, Jun Diao, Cheng-Zhi Chen, Shu-Qun Cheng, Fang Yuan, Jun-Lin He, Wei Li, Yin-Yin Xia

“…Health examination outcomes and radiation dose monitoring data will be collected and analyzed using the distributed lag non-linear model (DLNM) combined with generalized additive model (GAM) or generalized linear model (GLM) to evaluate the exposure-lag response relationship.DiscussionOur study will enhance our understanding of the exposure-lag response association between occupational radiation exposure and the health of radiation workers based on DLNM.Clinical trial registrationChinese Clinical Trials Registry, ChiCTR2400081804.…”
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Randomized Controlled Study Comparing Use of Propofol Plus Fentanyl versus Midazolam Plus Fentanyl as Sedation in Diagnostic Endoscopy in Patients with Advanced Liver Disease by Sameh Abdelkhalik Ahmed, Amal Selim, Nehad Hawash, Ahmed Khaled Tawfik, Mohamed Yousef, Abdelrahman Kobtan, Rehab Badawi, Sally Elnawasany, Reham Abdelkader Elkhouly, Amr Shaaban Hanafy, Fatma H. Rizk, Loai Mansour, Sherief Abd-Elsalam

“…The trial is registered with ClinicalTrials.gov Identifier: NCT03063866.…”
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Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma by Michael Dolph, Gabriel Tremblay, Adrienne M Gilligan, Hoyee Leong

“…**Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin... by Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Marek Szudrowicz, Magdalena Łanocha, Jan Jakub Kulczycki, Karol Turkiewicz, Katarzyna Woźnica, Maciej Lesiak, Adrian Doroszko

“…Nevertheless, further large randomized clinical trials are needed to confirm fully our results.…”
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