Is it time to agree upon a standardised approach to the assessment of contributing factors and impacts of adolescent pelvic pain? by Dehlia Moussaoui, Olivia G. Farrell, Sonia R. Grover

“…Future research should focus on the development of consensus amongst researchers as well as input from young women to establish a standardised international approach to clinical trials involving the investigation and reporting of pelvic pain in adolescents. …”
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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

“…This narrative review underscores the need for continued research into the molecular mechanisms underlying these interactions and suggests future directions for therapeutic development, including clinical trials, biomarker discovery, and combination therapies that synergistically target aging processes.…”
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Novel fusion protein REA induces robust prime protection against tuberculosis in mice by Sintayehu Kebede Gurmessa, Han-Gyu Choi, Yong Woo Back, Zongyou Jiang, Thuy An Pham, Seunga Choi, Hwa-Jung Kim

“…Abstract While many novel candidates for tuberculosis vaccines are presently undergoing pre-clinical or clinical trials, none of them have been able to eliminate infection entirely. …”
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Effect of COVID-19 on Pregnancy and Neonate’s Vital Parameters: A Systematic Review by Anna Charuta, Monika Smuniewska, Zofia Woźniak, Agnieszka Paziewska

“…In order to analyse the available research literature, the Web of Science, Scopus, and PubMed databases were used, in which the search for articles was conducted using terms (“pregnancy,” “coronavirus,” “SARS-CoV-2,” and “newborn”) and using PRISMA (Preferred Reporting Items for Systemic Reviews and Meta-Analysis) guidelines for clinical trials. Meta-analyses and systematic reviews (2022–2023) on symptoms, neonatal course, and risk of COVID-19 infection have been summarized. …”
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The Effect of Long-Term Exercise on the Production of Osteoclastogenic and Antiosteoclastogenic Cytokines by Peripheral Blood Mononuclear Cells and on Serum Markers of Bone Metabol... by J. Kelly Smith, Rhesa Dykes, David S. Chi

“…This trial is registered with Clinical Trials.gov Identifier: NCT02765945.…”
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Reducing the urge to be physically active in patients with anorexia nervosa through virtual reality: protocol for a randomised-controlled feasibility trial by Nina Timmesfeld, Georgios Paslakis, Georg Halbeisen

“…The findings will be published with open access.Trial registration number DRKS00035681, German Clinical Trials Register.…”
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The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis by Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin, Jan A. Plock

“…A trend towards potential promotion of both breast cancer growth and invasion by ADSCs found in basic science studies was indeed not confirmed in clinical trials. Whether experimental findings eventually correlate with or will be predictive of clinical outcomes remains unclear. …”
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Autologous Stem Cell Therapy in Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Houlong Luo, Yusheng Zhang, Qinghui Wang, Chenhui Zhou, Daohua Xu

“…A systematic literature search was performed in the SinoMed, PubMed, Embase, ClinicalTrials.gov, and Cochrane Controlled Trials Register databases from building database to January 2018. …”
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Baseline shock index and baroreflex function in older adults by Kenneth M. Madden, Boris Feldman, Graydon S. Meneilly

“…Autonomic dysfunction is associated with lower SI in older adults, potentially masking circulatory instability.ClinicalTrials.gov ID NCT01914133…”
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Unveiling the Emerging Role of Xanthine Oxidase in Acute Pancreatitis: Beyond Reactive Oxygen Species by Chenxia Han, Yaling Wu, Juan Rong, Qing Xia, Dan Du

“…This review summarized the benefits and contradictions of using XO inhibitors in animal models, offered mechanisms other than ROS, and discussed the difficulties faced in clinical trials. We hope to provide a perspective on the future worthwhile basic and clinical research on XO by analyzing its chemical and biological characteristics, as well as the progress of its regulatory mechanisms in AP.…”
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DIAMACC: protocol of a prospective diagnostic accuracy study of the maximal systolic acceleration to detect peripheral arterial disease in patients with diabetes-related foot ulcer... by Jaap Hamming, Siem Willems, Abbey Schepers, Jeroen J W M Brouwers

“…A full lower limb arterial DUS will serve as reference test.Ethics and dissemination Study protocol approval was gained from the Medical Ethical Committee Leiden/Den Haag/Delft and registered at ClinicalTrials.gov. The findings of this study will be reported through peer-reviewed publications and (inter)national conferences.Trial registration number NCT05646147.…”
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Diagnostic Model of In-Hospital Mortality in Patients with Acute ST-Segment Elevation Myocardial Infarction Used Artificial Intelligence Methods by Yong Li

“…We registered this study with the registration number ChiCTR1900027129 (the WHO International Clinical Trials Registry Platform (ICTRP) on 1 November 2019).…”
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Effect of acupuncture on patients with major psychiatric disorder and related symptoms caused by earthquake exposure: Protocol for a scoping review of clinical studies. by Hui-Ju Kwon, Jungtae Leem, Da-Woon Kim, Chan-Young Kwon, Sang-Ho Kim

“…These results will be helpful for developing disaster site-specific research protocols for future clinical trials on this topic.…”
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Comparative antidepressant effects and safety of intravenous racemic ketamine, psilocybin and theta burst stimulation for major depressive disorder: A systematic review and network... by Itsuki Terao, Wakako Kodama

“…We systematically searched the CENTRAL, Medline, CINHAL, and ClinicalTrials.gov databases for randomized controlled trials up to July 4, 2024. …”
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Adverse Effects of Carbetocin versus Oxytocin in the Prevention of Postpartum Haemorrhage after Caesarean Section: A Randomized Controlled Trial by D. Mannaerts, L. Van der Veeken, H. Coppejans, Y. Jacquemyn

“…The study was registered in the International Journal of Clinical Trials (ISRCTN 95504420, 2/2017).…”
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Relationship of Retinal Vessel Caliber with Age-Related Macular Degeneration by Sara Toulouie, Sean Chang, Julia Pan, Kiersten Snyder, Glenn Yiu

“…This trial is registered with ClinicalTrials.gov Identifier: NCT00000145.…”
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Risk Factors of Periprocedural Bradycardia during Primary Percutaneous Coronary Intervention in Patients with Acute ST-Elevation Myocardial Infarction by Yong Li, Shuzheng Lyu

“…We registered this study with WHO International Clinical Trials Registry Platform (ICTRP) (registration number: ChiCTR1900023214; registered date: 16 May 2019).…”
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Advancing inclusive research calculator for oncology disease areas: A resource to support the development of enrollment targets in diversity action plans for industry sponsors. by David J Press, Spencer L James, Bruno Jolain, Nicole Richie

“…Defining reliable methodology for measures and benchmarks is critical to ensuring adequate and consistent representation of historically underrepresented patient populations in clinical trials.<h4>Methods</h4>We provide an Advancing Inclusive Research (AIR) Calculator, summary tables, and data query bank to support target setting for the development of diversity action plans and to take steps toward defining enrollment standards. …”
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Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats by J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse

“…Schwann cell (SC) transplantation exhibits significant potential for spinal cord injury (SCI) repair and its use as a therapeutic modality has now progressed to clinical trials for subacute and chronic human SCI. Although SC implants provide a receptive environment for axonal regrowth and support functional recovery in a number of experimental SCI models, axonal regeneration is largely limited to local systems and the behavioral improvements are modest without additional combinatory approaches. …”
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Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques by Shery Jacob, Fathima Sheik Kather, Sai H. S. Boddu, Mahesh Attimarad, Anroop B. Nair

“…This article summarizes key stabilizers, polymers, surfactants, and excipients used in NS formulations, along with ongoing clinical trials and recent patents. Furthermore, a comprehensive analysis of various methods for NS preparation is provided. …”
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