Prevalence, risk factors, and adverse outcomes of bacterial vaginosis among pregnant women: a systematic review by Neha Sethi, Vallikkannu Narayanan, Rahmah Saaid, Aizura Syafinaz Ahmad Adlan, Soo Tein Ngoi, Cindy Shuan Ju Teh, Mashitah Hamidi, on behalf of WHOW research group

“…PubMed, ScienceDirect, ClinicalTrials.gov and Cochrane database searches were conducted independently by two authors until May 13th, 2023. …”
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Exoscope-assisted spine surgery: Current applications and future directions–A short review by Tomas Ferreira, Sakshi Roy, Joecelyn Kirani Tan, Wireko Andrew Awuah, Vallabh Shet, Favour Tope Adebusoye, Adrenito Nicolas, Toufik Abdul-Rahman

“…Addressing these limitations by conducting large-scale clinical trials and exploring the integration of artificial intelligence (AI) could assist in realising the potential of exoscopes in spine surgery.…”
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Experimental hypothermia by cold air: a randomized, double-blind, placebo-controlled crossover trial by Ane M. Helland, Sigurd Mydske, Jörg Assmus, Guttorm Brattebø, Øystein Wiggen, Haakon K. Kvidaland, Øyvind Thomassen

“…We have developed a new method for clinical trials of experimental hypothermia, to enable further studies of active rewarming. …”
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Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…As IL-12-NS delivers logarithmically lower amounts of IL-12 than previously administered during human clinical trials, our data reflect the importance of IL-12-NS which safely create a systemic immunostimulatory environment.…”
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Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Young Adult Male Athletes with Pa... by Shahnaz Hasan, Asma Alonazi, Shahnawaz Anwer, Azfar Jamal, Suhel Parvez, Faiz Abdulaziz Saleh Alfaiz, Heng Li

“…This trial is registered at Clinical Trials.gov under the identifier NCT05055284.…”
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Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis by Xin Wang, Ying Wang, Fenghua Zhou, Minxing Gao, Lingyuan Xu, Heying Wang, Jinan Song, Xiaoqiu Yang

“…Our study aims to systematically review the safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding.Methods and analysis The Cochrane Library, Web of Science, PubMed, Embase and ClinicalTrials.gov databases will be systematically searched, and all relevant articles in English from the establishment of the databases to January 2022 will be reviewed. …”
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An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors by Russell J. Schilder, Drew Rasco, Manish R. Sharma

“…Methods: This phase 1, open-label, dose-finding study evaluated the maximum tolerated dose (MTD), safety, efficacy, and pharmacokinetics of ESK-440 in participants with advanced or metastatic solid tumors (ClinicalTrials.gov: NCT01922752). A 3 + 3 dose-escalation design, with daily doses ranging from 25 to 700 mg/day of ESK-440 for each 28-day treatment cycle (6 to 8 cycles) was utilized to identify the MTD. …”
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The Predictive Value of Urinary Kidney Injury Molecular 1 for the Diagnosis of Contrast-Induced Acute Kidney Injury after Cardiac Catheterization: A Meta-Analysis by Qing Li, Yimin Huang, Weifeng Shang, Ying Zhang, Yanyan Liu, Gang Xu

“…Medline, Embase, ClinicalTrials.gov, Cochrane Library database, and the China National Knowledge Infrastructure (CNKI) were used to identify relevant studies from their inception to November 31, 2019. …”
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How many stroke survivors develop problematic spasticity requiring pharmacological therapy? An international (Europe and USA) observational study protocol by Pascal Maisonobe, Sergiu Groppa, Simon Page, Richard D Zorowitz, Laura Serrano Barrenechea, Simon Butet, David Hernández Herrero, Rama Prasad, Susan Sandars, Seema Meloni, Alessandro Picelli

“…Lay summaries will be prepared to accompany the primary paper and will also be provided to study participants.Trial registration number ClinicalTrials.gov NCT06055725.…”
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Chemometric Methods—A Valuable Tool for Investigating the Interactions Between Antifungal Drugs (Including Antifungal Antibiotics) and Food by Agnieszka Wiesner-Kiełczewska, Paweł Zagrodzki, Alicja Gawalska, Paweł Paśko

“…The input dataset comprised information from published clinical trials, chemical records, and calculations. We constructed PLS models with changes in the pharmacokinetic parameters (∆AUC, area under the curve; ∆C_max, maximum drug concentration; and ∆T_max, time to reach maximum drug concentration) after dietary intervention as the response parameters and eight groups of molecular descriptors (M1–M8) as the predictor parameters. …”
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Vicarious trauma, coping strategies and nurses' health outcomes: An exploratory study by Ilenia Piras, Vanessa Usai, Paolo Contu, Maura Galletta

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Pancreatic Cancer: Current Concepts, Trends, and Future Directions by Patrick Wenzel, Carolin Mogler, Kıvanç Görgülü, Hana Algül

“…Over the last 2 decades, clinical trials have significantly improved disease prognosis and patient survival. …”
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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…While results suggest that one year of L and Z supplementation may have limited effects on structural brain outcomes overall, there may be a subsample of individuals for whom supplementation of L and Z provides greater benefits. ClinicalTrials.gov number, NCT02023645.…”
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Noninvasive Neurally Adjusted Ventilator Assist Ventilation in the Postoperative Period Produces Better Patient-Ventilator Synchrony but Not Comfort by L. O. Harnisch, U. Olgemoeller, J. Mann, M. Quintel, O. Moerer

“…The trial was registered at the German clinical Trials Register (DRKS no.: DRKS00005408).…”
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Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment by Mohamed E. Awad, Khaled A. Hussein, Inas Helwa, Mohamed F. Abdelsamid, Alexandra Aguilar-Perez, Ibrahim Mohsen, Monte Hunter, Mark W. Hamrick, Carlos M. Isales, Mohammed Elsalanty, William D. Hill, Sadanand Fulzele

“…The aim of this study is to review all the published clinical trials on autologous bone marrow mesenchymal stem cells (BM-MSCs) in the repair of cartilage lesions of the knee. …”
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Role of Platelet-rich Plasma in Unexplained Recurrent Implantation Failure – A Systematic Review and Meta-analysis of Randomised Control Trials by Harpreet Kaur, Meenakshi Meenu, Shivam Pandey, Anil Chauhan, Mishu Mangla

“…Materials and Methods: An electronic database search for randomised clinical trials comparing PRP against routine care in women with unexplained RIF was performed on PubMed, EMBASE, SCOPUS and Cochrane Central. …”
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Three-dimensional dynamics of mesothelin-targeted CAR.CIK lymphocytes against ovarian cancer peritoneal carcinomatosis by Federica Galvagno, Valeria Leuci, Annamaria Massa, Chiara Donini, Ramona Rotolo, Sonia Capellero, Alessia Proment, Letizia Vitali, Andrea Maria Lombardi, Valentina Tuninetti, Lorenzo D’Ambrosio, Alessandra Merlini, Elisa Vigna, Giorgio Valabrega, Luca Primo, Alberto Puliafito, Dario Sangiolo

“…Abstract Intraperitoneal cellular immunotherapy with CAR-redirected lymphocytes is an intriguing approach to target peritoneal carcinomatosis (PC) from ovarian cancer (OC), which is currently evaluated in clinical trials. PC displays a composite structure with floating tumor cells within ascites and solid-like masses invading the peritoneum. …”
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Clinical Burden of Chronic Obstructive Pulmonary Disease in Patients with Suboptimal Peak Inspiratory Flow by Jill A. Ohar, Donald A. Mahler, Gabrielle N. Davis, David A. Lombardi, Edmund J. Moran, Glenn D. Crater

“…To assess the clinical burden of COPD by characterizing the clinical characteristics of participants with sPIF against medium-low resistance DPIs versus those with optimal PIF (oPIF) from two phase 3 clinical trials. Methods. Baseline data were collected from two randomized, controlled, phase 3 trials (NCT03095456; NCT02518139) in participants with moderate-to-severe COPD. oPIF (60 L/min) against the medium-low resistance DPIs was used as the threshold for defining the PIF subgroups (<60 L/min (sPIF) vs ≥60 L/min (oPIF)). …”
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Classifications of haemodialysis vascular access stenosis: a scoping review by Petr Waldauf, Michael Corr, Stephen O’neill, Katerina Lawrie, Jan Malik, Libor Janousek, Stepan Maly, Jaroslav Chlupac

“…This review aims to present a comprehensive summary and propose further methodological approaches.Design A systematic review of the literature, evaluating classifications for dialysis-related VA stenosis.Data sources Web of Science, Scopus, PubMed, Google Scholar and the ClinicalTrials.gov registry were searched from inception to 7 December 2024.Eligibility criteria All articles containing classifications regarding dialysis VA were eligible, with no restrictions on the study type or language of the full text.Data extraction and synthesis Two independent researchers performed the search and initial screening. …”
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Mesenchymal Stem Cells Enhance Pulmonary Antimicrobial Immunity and Prevent Following Bacterial Infection by Wenchao Li, Weiwei Chen, Saisai Huang, Xiaojun Tang, Genhong Yao, Lingyun Sun

“…As a promising substitution/adjunct, mesenchymal stem cells (MSCs) are currently being tested in several clinical trials. However, their influence on the recipients’ antimicrobial immunity remains unclear. …”
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