The role of informal caregivers in suicide prevention for men– findings from a psychological autopsy study by Laura Hofmann, Anna-Lena Springer, Birgit Wagner

“…Trial registration German Clinical Trials Register, DRKS00030758, Registered on 11.11.2022.…”
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Effect of implant abutment surface treatments on bacterial biofilm composition and structure by Eduardo Anitua, Alia Murias-Freijo, Roberto Tierno, Ricardo Tejero, Mohammad Hamdan Alkhraisat

“…Nevertheless, there is a lack of clinical trials that assess the biofilm formation on TiN abutments in the context of clinical practice. …”
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Effectiveness of Palivizumab in Preventing RSV Hospitalization in High Risk Children: A Real-World Perspective by Nusrat Homaira, William Rawlinson, Thomas L. Snelling, Adam Jaffe

“…This recommendation is based on evidence of efficacy when used under clinical trial conditions. However the real-world effectiveness of palivizumab outside of clinical trials among different patient populations is not well established. …”
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Epigenetic regulation of the inflammatory response in stroke by Jingyi Liang, Fei Yang, Zixiao Li, Qian Li

“…Suppressing the inflammatory response has been shown to mitigate this cascade of events in experimental stroke models. However, in clinical trials of anti-inflammatory agents, long-term immunosuppression has not demonstrated significant clinical benefits for patients. …”
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Bio-Tribocorrosion of Titanium Dental Implants and Its Toxicological Implications: A Scoping Review by Sumit Gaur, Rupali Agnihotri, Sacharia Albin

“…However, further validation of the role of bio-tribocorrosion on the durability of the Ti dental implants and Ti toxicity is warranted through clinical trials.…”
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Managing pediatric psoriasis: update on treatments and challenges—a review by A. A. Hebert, J. Browning, P. C. Kwong, A. M. Duarte, H. N. Price, E. Siegfried

“…A growing number of clinical trials using biologic agents for pediatric psoriasis aim to broaden available treatment options but may also raise unique concerns associated with the use of these medications in children.Conclusion Pediatric psoriasis is underrecognized and often undertreated. …”
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The Efficacy of Conbercept in Polypoidal Choroidal Vasculopathy: A Systematic Review by Yimin Wang, Mengxi Shen, Jinwei Cheng, Xiaodong Sun, Peter K. Kaiser

“…The use of antivascular endothelial growth factor (VEGF) therapy in polypoidal choroidal vasculopathy (PCV), a subtype of neovascular age-related macular degeneration (nAMD), has been well established in randomized clinical trials. This meta-analysis has evaluated the efficacy of a novel anti-VEGF agent, conbercept, in the management of PCV using ranibizumab and aflibercept as the reference agents. …”
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Busting the Breast Cancer with AstraZeneca’s Gefitinib by S. Chemmalar, A. R. Intan Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, Kim Wei Chan, Md Zuki Abu Bakar Zakaria

“…Unfortunately, in clinical trials, GEF did not show the outcomes expected with complete response and disease progress. …”
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Non-Instrumental Pulp Therapy for Deciduous Molars: A Global Bibliometric Analysis of Clinical Studies by Rayza Verônica Soares Carvalho, Marina de Deus Moura de Lima, Cacilda Castelo Branco Lima, Marcoeli Silva de Moura, Caroline Barros Oliveira, Lucia de Fátima Almeida de Deus Moura

“…Japan had the highest number of citations (n=80). Clinical trials were the most common study design (n= 6). …”
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Role of nutritional factors at the irritable bowel syndrome by Yu. O. Shulpekova, A. V. Sedova

“…Efficacy of functional food products containing bacteria of probiotic strain Bifidobacterium animalis sp. lactis DN-173 010 for treatment of IBS symptoms is demonstrated in clinical trials. At detection of symptoms link to intake of specific products it is necessary to exclude food allergy and enzymopathies (e.g. lactase deficiency), which should be defined as independent diseases under the «mask» of irritable bowel syndrome.Conclusion. …”
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Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions by Ghaleb Elyamany, Eman Al Mussaed, Ali Matar Alzahrani

“…The introduction of genes encoding artificial receptors called chimeric antigen receptors (CARs) and CAR-modified T cells targeted to the B cell-specific CD19 antigen have demonstrated promising results in multiple early clinical trials. The aim of this paper is to review the recent advances in epidemiology; pathophysiology; clinical, pathologic, and molecular characteristics; therapy; and outcome in patients with PBL.…”
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Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy by Ronaldo J. F. C. do Amaral, Henrique V. Almeida, Daniel J. Kelly, Fergal J. O’Brien, Cathal J. Kearney

“…We conclude with a perspective for future clinical trials using IFP stem cells.…”
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Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment by Rahul Navab, Pragyat Futela, Verkha Kumari, Jayesh Valecha, Ramansh Bandhu Gupta, Rohit Jain

“…These therapies exhibit impressive efficacy in clinical trials, leading to FDA approvals for specific MM patient populations. …”
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Ethnopharmacology, Biological Evaluation, and Chemical Composition of Ziziphus spina-christi (L.) Desf.: A Review by Mahmoud Dogara Abdulrahman, Ali Muhammad Zakariya, Harmand A. Hama, Saber W. Hamad, Sawsan S. Al-Rawi, Sarwan W. Bradosty, Ahmad H. Ibrahim

“…However, the safety and efficacy of Z. spina have not been wholly assessed in humans, and further well-designed clinical trials are needed to corroborate preclinical findings. …”
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Challenges in Assessing Outcomes among Infants of Pregnant HIV-Positive Women Receiving ART in Uganda by Barbara Castelnuovo, Frank Mubiru, Ivan Kalule, Shadia Nakalema, Agnes Kiragga

“…We report very low documented HIV transmission comparable with those reported in clinical trials settings; however, demonstrating the efficacy of Option B-plus in terms of averted transmission in routine settings is challenging since high proportion of infants do not have documented HIV tests.…”
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Antireflux mucosal valvuloplasty versus proton pump inhibitors for the treatment of patients with gastro-oesophageal reflux disease in a tertiary healthcare centre in China: study... by Xiaofen Lv, Yunqing Zeng, Wenlong Ma, Jiaoyang Lu

“…Study results will be disseminated through peer-reviewed journals and presented at scientific conferences.Trial registration number ClinicalTrials.gov (NCT 06348420).…”
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Efficacy of Abiraterone and Enzalutamide in Pre- and Postdocetaxel Castration-Resistant Prostate Cancer: A Trial-Level Meta-Analysis by Mike Fang, Mary Nakazawa, Emmanuel S. Antonarakis, Chun Li

“…The results from this comprehensive meta-analysis suggest a survival advantage with the use of first-line enzalutamide over abiraterone in CRPC and highlight the need for prospective clinical trials.…”
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Association between dietary intake of live microbes and chronic obstructive pulmonary disease: a cross-sectional study of NHANES 2007–2012 by Yifeng Xu, Zhaoqi Yan, Liangji Liu

“…Trial registration ClinicalTrials.gov Identifier NCT00005154 First Posted date 26/05/2000(retrospectively registered).…”
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Mechanisms Underlying the Osteo- and Adipo-Differentiation of Human Mesenchymal Stem Cells by Yu Zhang, Dilaware Khan, Julia Delling, Edda Tobiasch

“…In this review, the current findings for adipo- and osteo-differentiation are summarized together with a brief statement on first clinical trials.…”
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Exploring the associations between the biomechanical and psychological mechanistic pathways of lower back pain development amongst persons with lower-limb amputation: A study proto... by Alexandra Withey, Dario Cazzola, Abby Tabor, Elena Seminati

“…<h4>Trial reference number</h4>The study is registered at IRAS ID: 321729 and at ClinicalTrials.gov: NCT06243549.…”
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