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1481
Scoping review on prevention of suicidal thoughts and behaviors in adolescents: methods, effectiveness and future directions
Published 2024-06-01“…In this comprehensive scoping review, our objective was to provide insights into prevention methods for suicidal thoughts and behaviors directed towards adolescents, including their effectiveness, public perception, and potential adaptations.MethodA scoping review was conducted, encompassing 71 articles including systematic review, clinical trials and qualitative studies for a wider understanding. …”
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1482
Exosomes in neuron-glia communication: A review on neurodegeneration
Published 2024-09-01“…Furthermore, an exploration of the Clinicaltrials.gov database was undertaken to identify clinical trials related to cellular signaling, utilizing analogous terminology. …”
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1483
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1484
Assessment of Negative Symptoms in Schizophrenia: From the Consensus Conference-Derived Scales to Remote Digital Phenotyping
Published 2025-01-01“…However, psychometric validation of these scales is still in progress, and they are not yet recommended by regulatory agencies, thus limiting their use in clinical trials and settings. Complementing these traditional methods, remote digital phenotyping offers a novel approach by leveraging smartphones and wearable technology to capture real-time, high-resolution clinical data. …”
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1485
Physical and cognitive-based training in healthy older adults: Evidence from a systematic review and meta-analysis
Published 2024-03-01“…Methods: For this systematic review and meta-analysis, randomized clinical trials (RCTs) published between 2000 and 6 February 2023 were extracted from several electronic databases, including, ProQuest, PubMed, Scopus, Embase, and Web of Science. …”
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1486
US Pilot Study of Lumbar to Sacral Nerve Rerouting to Restore Voiding and Bowel Function in Spina Bifida: 3-Year Experience
Published 2014-01-01“…This trial is registered with ClinicalTrials.gov NCT00378664.…”
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1487
COVID-19 vaccination: challenges in the pediatric population
Published 2025-01-01“…An analysis of recent published studies reveals that the majority of clinical trials have reported a sustained immune response following COVID-19 vaccination in children across various age groups worldwide. …”
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1488
Cytokine Profile of Patients with Allergic Rhinitis Caused by Pollen, Mite, and Microbial Allergen Sensitization
Published 2017-01-01“…Thus, along with other clinical trials, the study performed would clarify some aspects of molecular pathogenesis of human allergic rhinitis.…”
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1489
Protocol for visual-acoustic intervention with service delivery in-person and via telepractice (VISIT) non-inferiority trial for residual speech sound disorder
Published 2025-01-01“…Trial registration ClinicalTrials.gov identifier NCT06517225, 07/23/2024. …”
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1490
Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study
Published 2025-02-01“…Negative effects were reported in terms of increased adverse emotional experiences.DiscussionThe investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness.…”
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1491
The effect of physical activity on markers of oxidative and antioxidant stress in cancer patients: a systematic review and meta-analysis
Published 2025-01-01“…Results In the end, 7 randomized controlled clinical trials were included, totaling 573 participants. …”
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1492
A Systematic Literature Review of Three Stenting Strategies for Bifurcation Lesions in Coronary Artery Disease
Published 2019-04-01“…**Methods:** Literature searches in Medline, Cochrane Library, Web of Science and Embase were conducted to identify prospective clinical trials from January 2007-July 2017. **Results:** 602 articles were identified. …”
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1493
Relationships of dermatologic symptoms and quality of life in patients with psoriatic arthritis: analysis of two tofacitinib phase III studies
Published 2022-07-01“…Rheumatologists should be aware of dermatologic manifestations and QoL impacts in patients with PsA.ClinicalTrials.gov NCT01877668; NCT01882439…”
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1494
Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab
Published 2014-01-01“…This new case of successful use of rituximab in HSP promotes more investigations of this treatment in clinical trials.…”
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1495
Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury
Published 2025-01-01“…Future studies should focus on more targeted randomized clinical trials.…”
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1496
Effect of electrical stimulation with a cochlear implant on tinnitus impact: protocol of an individual patient data meta-analysis
Published 2022-06-01“…We will also apply prediction models to individual patient data (IPD) of clinical trials to find predictive factors of the effect of electrical stimulation on tinnitus impact.Method and analysis The IPD meta-analysis is a follow-up project of the systematic review on cochlear implantation in patients with tinnitus as a primary complaint. …”
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1497
Efficacy of vaccines based on chimeric or multiepitope antigens for protection against visceral leishmaniasis: A systematic review.
Published 2024-12-01“…<h4>Principal findings</h4>A total of 22 studies were selected, with only one being a randomized clinical trial. Most of the studies were conducted with mice, followed by dogs and hamsters. …”
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1498
High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
Published 2025-01-01“…A comprehensive literature search was undertaken for published papers in PubMed, Embase, EBSCO, ICTRP, and the NIH clinical trials databases. Results. A total of 16 reports from 14 studies were included in this paper. …”
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1499
Abrocitinib monotherapy in Investigator’s Global Assessment nonresponders: improvement in signs and symptoms of atopic dermatitis and quality of life
Published 2022-07-01“…Outcomes measuring skin clearance, itch, and quality of life were evaluated.Results Both nonresponders (n = 548) and responders (n = 260) treated with abrocitinib had rapid and clinically meaningful improvement in skin clearance, itch, and quality of life compared with placebo.Conclusion Patients with moderate-to-severe atopic dermatitis treated with abrocitinib who did not achieve an Investigator’s Global Assessment 0/1 response at week 12 still experienced rapid, clinically meaningful improvements across several other validated measures of efficacy and quality of life.ClinicalTrials.gov NCT02780167, NCT03349060, NCT03575871…”
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1500
Knowledge on hydroxychloroquine prescription and attitude toward its use in COVID-19 – A survey-based study among doctors
Published 2021-01-01“…A significantly higher number of these physicians opposed the use of HCQ in clinical trials (26.82% vs. 8.1%, P = 0.027) and health-care/contact prophylaxis (41.5% vs. 16.2%, P = 0.008). …”
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