Lobar Hepatocellular Carcinoma with Ipsilateral Portal Vein Tumor Thrombosis Treated with Yttrium-90 Glass Microsphere Radioembolization: Preliminary Results by M. Pracht, J. Edeline, L. Lenoir, M. Latournerie, H. Mesbah, O. Audrain, Y. Rolland, B. Clément, J. L. Raoul, E. Garin, E. Boucher

“…Treating lobar hepatocellular carcinoma with ipsilateral portal vein thrombosis with yttrium-90 glass-microsphere radioembolization is safe and efficacious. Further clinical trials are warranted to confirm these results and to compare 90Y-microS with sorafenib, taking into account not only survival but also the possibility of secondary surgery for putative curative intention after downstaging.…”
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Evaluation of Vitrectomy with Planned Foveal Detachment as Surgical Treatment for Refractory Diabetic Macular Edema with or without Vitreomacular Interface Abnormality by Ahmed M. Abdel Hadi

“…The study has been registered in Contact ClinicalTrials.gov PRS Identifier: NCT03345056.…”
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A review on phytogenic compounds inhibit coronaviruses associated with respiratory syndrome in human by Majid Gholami-Ahangaran, Maryam Karimi-Dehkordi

“…Results: Some of the key compounds showing promising effects for the treatment of coronavirus in humans include scutellarein, silvestrol, tryptanthrin, psychosaponin B2, and lectins such as griffithsin, lycorine, and polyphenolics including quercetin, myristicin, caffeic acid, and isobavachalcone. The conducting clinical trials on humans, in vitro and in vivo tests are required to determine the level of safety, as well as to determine the therapeutic level for each compound. …”
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Improvement of Mouth Functional Disability in Systemic Sclerosis Patients over One Year in a Trial of Fat Transplantation versus Adipose-Derived Stromal Cells by Maria Giuseppina Onesti, Paolo Fioramonti, Sara Carella, Pasquale Fino, Cinzia Marchese, Nicolò Scuderi

“…The present clinical experimentation should be regarded as a starting point for further experimental research and clinical trials.…”
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The mRNA-1647 vaccine: A promising step toward the prevention of cytomegalovirus infection (CMV) by Adewunmi Akingbola, Abiodun Adegbesan, Olajumoke Adewole, Kolade Adegoke, Akpevwe Emmanuella Benson, Paul Ayomide Jombo, Sandra Uchechukwu Eboson, Victor Oluwasola, Ademola Aiyenuro

“…We have reviewed results from Phase 1 and 2 clinical trials of the mRNA-1647 vaccine, demonstrating robust immune responses in both seronegative and seropositive participants. …”
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Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism by Daniel Q. Li, Mathieu Gauvin, Guillermo Rocha, Pierre Trottier, Louis Racine, Avi Wallerstein

“…Trial registration This trial was retrospectively registered on ClinicalTrials.gov with the trial registration number NCT06742541.…”
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The Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review by Ninel Iacobus Antonie, Gina Gheorghe, Vlad Alexandru Ionescu, Loredana-Crista Tiucă, Camelia Cristina Diaconu

“…Realizing this potential will require rigorous clinical trials, interdisciplinary collaboration, regulatory clarity, and tailored algorithmic improvements to ensure their safe and effective integration into clinical practice.…”
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Determining the Reliability and Validity of the Persian Version of Brief Problem MonitorTM for Ages 18-59 in Students by Meysam Tajamolian, Mohammadreza Shaeiri, Hojjatollah Farahani

“…Additionally, factor analysis demonstrated a good fit for the initial three-factor model.Discussion and Conclusion: BPM/18-59 demonstrates appropriate psychometric properties for application in research and clinical trials involving Iranian individuals.…”
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Parodontgel® on Wound Healing and Patient-Reported Outcome Measures (PROMs) after Tunneled Coronally Advanced Flap (TCAF) by Leonardo Mancini, Vincenzo Mancini

“…However, further investigations through randomized clinical trials are required to establish the potential benefits and broader applicability of such healing gel applications in the context of periodontal plastic surgery.…”
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Evaluation of Novel Stereotactic Cannula for Stem Cell Transplantation against Central Nervous System Disease by Masahito Kawabori, Aki Tanimori, Shinri Kitta, Hideo Shichinohe, Kiyohiro Houkin

“…We compared cannulas for cell delivery used in clinical trials, the Pittsburg and Mizuho cannulas, to a newly designed one, MK01, to assess their usability. …”
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The Stability-Indicating Ultra High-Performance Liquid Chromatography with Diode Array Detector and Tandem Mass Spectrometry Method Applied for the Forced Degradation Study of Ritl... by Jelena Kovačić, Daniela Amidžić Klarić, Nikša Turk, Željko Krznarić, Emma Riordan, Ana Mornar

“…Background/Objectives: Janus kinase inhibitors open new horizons for small-molecule drugs in treating inflammatory bowel disease, with ritlecitinib demonstrating significant efficacy in clinical trials for ulcerative colitis and Crohn’s disease. …”
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The Taking Charge After Stroke (TaCAS) study protocol: a multicentre, investigator-blinded, randomised controlled trial comparing the effect of a single Take Charge session, two Ta... by Mark Weatherall, Harry McNaughton, Vivian Wai Yin Fu

“…Results will be published and presented at relevant stroke meetings within New Zealand and internationally, informing the use of a self-management intervention after stroke.Trial registration Australia and New Zealand Clinical Trials Registry ACTRN12615001163594. Date registered 02-11-2015. …”
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Recent progress in preventive effect of collagen peptides on photoaging skin and action mechanism by Chongyang Li, Yu Fu, Hongjie Dai, Qiang Wang, Ruichang Gao, Yuhao Zhang

“…More importantly, some clinical trials on the beneficial effect on skin of collagen peptides are also discussed. …”
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Evaluation of a Low-threshold Exercise And Protein supplementation intervention for Women (LEAP-W) experiencing homelessness and addiction: Protocol for a single-arm mixed methods... by Fiona Kennedy, Deirdre Murray, Clíona Ní Cheallaigh, Roman Romero-Ortuno, Julie Broderick

“…The findings of this research will help narrow the research gap and will guide clinicians and policy makers to implement unique gender-based treatment strategies for this population. (300).<h4>Clinical trials.gov number</h4>NCT05700305.…”
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Effect of intermittent urethral catheter clamping combined with active urination training (ICCAUT) strategy on postoperative urinary dysfunction after radical rectal cancer surgery... by Yuchen Guo, Quan Wang, Tingting He, Sen Liang, Yunan Guan, Jianan Sun, Haiyan Hu

“…All primary and secondary outcomes will be reported in peer-reviewed publications and at conference presentations.Trial registration number The trial was registered at ClinicalTrials.gov website, NCT06241703.…”
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Aortic intimal sarcoma with abdominal metastasis: case report and management approach by Gongji Yao, Gongji Yao, Jianwei Xu, Jianwei Xu

“…This case highlights the potential effectiveness of combined surgical and chemotherapeutic approaches for managing abdominal metastasis of aortic intimal sarcoma and provides a foundation for future clinical trials.…”
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Performance of Size 1 I-Gel Compared with Size 1 ProSeal Laryngeal Mask in Anesthetized Infants and Neonates by Gulay Erdogan Kayhan, Zekine Begec, Mukadder Sanli, Ender Gedik, Mahmut Durmus

“…This trial is registered with: ClinicalTrials.gov NCT01704118.…”
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CRISPR-Cas9 in basic and translational aspects of cancer therapy by Maryam Samareh Salavatipour, Zahra Poursalehi, Negin Hosseini Rouzbahani, Sohaib Mohammadyar, Mohammad Vasei

“…Clinicaltrials.gov, a resource that provides access to information on clinical trials, was also searched in this review. Results: We have defined the basics of this technology and then mentioned some clinical and preclinical studies using this technology in the treatment of a variety of solid tumors as well as hematologic neoplasms. …”
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Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock by Shuxian Zhang, Minglu Yang, Tao Xu, Qiongxian Yan, Allan Degen, Xiaoling Zhou

“…Wolff (P. thellungiana), a medicinal herb, has been reported to relieve growth retardation and overexertion in ethnopharmacological clinical trials. This paper summarizes and classifies a total of 106 bioactive compounds that were isolated and identified from P. thellungiana, including flavonoids, simple phenylpropanoids, coumarins, volatile compounds, and simple polyphenols, and discusses its pharmaceutical benefits, including its growth-promoting, antioxidant, anti-inflammatory, anti-atherosclerotic, and hepatoprotective properties. …”
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Phenotypic insights into genetic risk factors for immune-related adverse events in cancer immunotherapy by Haochuan Ma, Dili Song, Haibo Zhang, Taidong Li, Xing Jin

“…Further investigation is crucial to validate and assess these identified risk factors within clinical trials. A mechanistic understanding of these causal factors is essential for improving the management and prevention of irAEs.…”
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