Successful Treatment of Hepatitis C with Simeprevir, Sofosbuvir, and Ribavirin in an HIV Coinfected Liver Transplant Patient with Advanced Chronic Kidney Disease by Anna Maruyama, Trana Hussaini, Nilufar Partovi, Siegfried R. Erb, Vladimir Marquez Azalgara, Nadia Zalunardo, Neora Pick, Mark Hull, Eric M. Yoshida

“…The new DAAs show promise for HIV coinfected patients and those with severe to end-stage renal disease (ESRD); however, robust clinical trials or large cohort studies will need to be conducted to confirm the efficacy and safety of these newer agents in this setting.…”
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PRESBYACOUSSIS: JUSTIFICATION OF DIAGNOSIS IN SCREENING CONDITIONS by K.E. Gubskaya, M.M. Baibulov, Dinara Urazalina, Gulnara Tuleshova

“…After selection and analysis, the results of 6 studies were taken into work, including 3 randomized clinical trials and 3 observational studies. Taking into account global trends, an analysis of the validity of the search for effective methods for diagnosing presbycusis was carried out. …”
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Assessing the effectiveness of the SOLIO Alfa Cure Plus device in treating low back pain: a randomized controlled study by Hadari Yotam, Pesah Galia, Goor-Aryeh Itay, Ungar Lior

“…Trial registration: The clinical trials registration is 8475-21-SMC.…”
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Transcatheter mitral valve replacement to treat rheumatic mitral stenosis: a case series by Ping Jin, Hong Guo, Yu Mao, Mengen Zhai, Yang Liu, Jian Yang

“…The early results of the procedure are acceptable and provide bright prospects and directions for the precision treatment of RMS. Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT02917980).…”
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Management Practice and Clinical Outcomes of Dementia in Sub-Saharan Africa: A Systematic Review by Dessale Abate Beyene, Alemseged Beyene Berha

“…Finally, five randomized clinical trials (RCT) and three prospective cohort studies that were reported on the management practice and treatment outcome of dementia in SSA were eligible for analysis. …”
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Efficacy of Dental Bleaching with Whitening Dentifrices: A Systematic Review by Bruno G. S. Casado, Sandra L. D. Moraes, Gleicy F. M. Souza, Catia M. F. Guerra, Juliana R. Souto-Maior, Cleidiel A. A. Lemos, Belmiro C. E. Vasconcelos, Eduardo P. Pellizzer

“…Electronic systematic searches of PubMed/MEDLINE, Scopus, and the Cochrane Library were conducted for published articles. Only randomized clinical trials in adults that compared the use of so-called whitening dentifrices to the use of nonwhitening dentifrices were selected. …”
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Pancreatic Perivascular Epithelial Cell Tumor (PEComa) with Liver Metastasis: a Case Report and Literature Review by Yu. A. Stepanova, Kh. A. Ayvazyan, D. V. Kalinin, O. I. Zhavoronkova, V. S. Shirokov, A. V. Zhao

“…To determine clearer criteria for the diagnosis and differential diagnosis of PEComa, to identify criteria for the malignancy of these tumors, to develop treatment tactics and further dynamic monitoring, a set of statistical data of significant group and randomized clinical trials are needed. Pancreatic PEComas in this group are extremely rare and often have a benign course. …”
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Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting progr... by Mathieu Pereira, Lauriane Sedes, Emilie Gadéa, Rebecca Shankland

“…Trial registration This trial is registered on ClinicalTrials.gov : NCT06701877.…”
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Analgesic effect of intravesical lignocaine in urology surgery: A systematic review and meta-analysis by Ka T. Ng, Wei E. Lim, Wan Y. Teoh, Ahmad N. B. Fadzli, Mohd F. B. Z. Abidin

“…Methods: The MEDLINE, EMBASE, and CENTRAL databases were searched from their start date until December 2024. Randomised clinical trials (RCTs) were included, comparing intravesical lignocaine and control for bladder irrigation in adults undergoing urological surgery. …”
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Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis by Roberto Buonaiuto, Aldo Caltavituro, Margherita Tafuro, Alessandra Longobardi, Giuliana Pavone, Pierluigi De Santis, Roberta Caputo, Carmine De Angelis, Lucia Del Mastro, Fabio Puglisi, Mario Giuliano, Grazia Arpino, Martina Pagliuca, Michelino De Laurentiis

“…Although the magnitude of benefit appears to be independent of ethnicity, future clinical trials should devise a standardized method for stratifying patients by ethnicity to more effectively assess potential differences in treatment benefits. …”
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Study protocol for Video Images about Decisions to Improve Ethical Outcomes with Palliative Care Educators (VIDEO-PCE): a pragmatic stepped wedge cluster randomised trial of older... by Joshua R Lakin, Na Wang, Howard J Cabral, Michael K Paasche-Orlow, Charlotta Lindvall, Angelo Volandes, Aretha Delight Davis, Michael R Winter, Edward T Moseley, Lori Henault, Sophia N Zupanc, Sophiya Das, Kate Sciacca, Edith A Burns, Maria T Carney, Jennifer Itty, Santiago Lopez, Kaitlin Emmert, Narda J Martin, Sherene Lambert, Jennifer Polo, Shreya Sanghani, Julianne N Dugas, Michele Gomez, Shira Gabry-Kalikow, Alexandra Dobie, Meredith Amshoff, Traci Cucinotta, Milton Joel, Lisa B Caruso, Ana Maria Ramirez, Kathleen Salerno, Qausarat Ogunneye

“…This trial is registered at ClinicalTrials.gov.Trial registration number NCT04857060; ClinicalTrials.gov…”
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Case Reports: The core of practice-based evidence by Antonio Villa

“…The great value of case reports is shown by the fact that they are being increasingly published by scholar journals, in a time where researchers need to publish clinical trials and systematic reviews to get adequate visibility and more impact factor [2]. …”
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Identification and characteristics of distressed patients with coronary heart disease and insufficiently controlled medical risk factors: baseline findings and sex differences from... by Christoph Herrmann-Lingen, Christoph Herrmann-Lingen, Monika Sadlonova, Monika Sadlonova, Monika Sadlonova, Monika Sadlonova, Monika Sadlonova, Ingrid Becker, Kristina Bersch, Franziska Geiser, Martin Hellmich, Ingrid Kindermann, Matthias Michal, Mariel Nöhre, Astrid Petersmann, Astrid Petersmann, Rolf Wachter, Rolf Wachter, Rolf Wachter, Birgit Herbeck Belnap, Birgit Herbeck Belnap, Christian Albus

“…Women differed from men in relevant aspects of their RF profiles and mental health and should receive special attention in future analyses and treatment planning for patients with CHD.Clinical Trial RegistrationGerman Clinical Trials Register, https://drks.de/search/de/trial/DRKS00020824, identifier DRKS00020824.…”
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Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis by Yirui Zhai, Liming Wang, Hong Zhao, Fan Wu, Lingxia Xin, Feng Ye, Wei Sun, Yan Song, Lijuan Niu, Huiying Zeng, Jingbo Wang, Yuan Tang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Hao Jing, Shunan Qi, Wenwen Zhang, Shulian Wang, Ye-Xiong Li, Jianxiong Wu, Bo Chen

“…This phase II trial shows that concurrent sorafenib and radiotherapy is effective and well-tolerated in the treatment of advanced HCC with portal vein or hepatic vein tumor thrombosis. Clinical trials registration: This study is registered at ClinicalTrials.gov (NCT03535259).…”
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Organ preservation, for rectal cancer: general overview of the latest data from phase III randomized trials by Syrine Ben Dhia, Damien Chauviere, Diana Mitrea, Renaud Schiappa, Tanguy Pace Loscos, Emmanuel Chamorey, David Baron

“…Method: We searched for articles and abstracts on randomized clinical trials investigating OP approaches for rectal cancer, including data presented at the LUCARRE Congress held in Nice on November 25, 2023, covering ongoing and recently published trials on rectal preservation. …”
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Evaluation of Inflammatory Markers in a Large Sample of Obstructive Sleep Apnea Patients without Comorbidities by Izolde Bouloukaki, Charalampos Mermigkis, Nikolaos Tzanakis, Eleftherios Kallergis, Violeta Moniaki, Eleni Mauroudi, Sophia E. Schiza

“…This trial is registered with ClinicalTrials.gov number NCT03070769.…”
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Protocol for a scoping review on rehabilitation among individuals with traumatic brain injury who intersect with the criminal justice system. by Vincy Chan, Maria Jennifer Estrella, Zacharie Beaulieu-Dearman, Jessica Babineau, Angela Colantonio

“…Primary research articles that meet pre-defined inclusion criteria will be identified from electronic databases (MEDLINE® ALL, Embase and Embase Classic, Cochrane CENTRAL Register of Clinical Trials, CINAHL, APA PsycINFO, Applied Social Sciences Index and Abstracts, Criminal Justice Abstracts, Nursing and Allied Health, and Dissertation and These Global), reference lists of included articles, and scoping or systematic reviews. …”
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The pharmacology, toxicology, and detoxification of Aconitum kusnezoffii Reichb., traditional and modern views by Kenneth Happy, Sungyu Yang, Chang Ho Kang, Youngmin Kang

“…While research on this herb is extensive, gaps remain in clinical trials and efficacy studies. Further research is recommended to evaluate the quality of medicinal materials, understanding the herb’s pharmacodynamic substances, and assess long-term toxicity and clinical efficacy. …”
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MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY by Leila Akhvlediani, Marina Izmailovich, Meruyert Gazaliyeva, Anna Skvortsova, Kanan Tanriverdiev

“…Vitamin D, particularly 25(OH)D, plays a pivotal immunomodulatory role, supporting Treg and Breg cell function, and mitigating allergic inflammation. Clinical trials demonstrate that vitamin D supplementation enhances ASIT outcomes, especially in pediatric patients. …”
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Multiplex Tests for Respiratory Tract Infections: The Direct Utility of the FilmArray Respiratory Panel in Emergency Department by Siyuan Yang, Hui Li, Yunxia Tang, Fengting Yu, Chengjie Ma, Huimin Zhang, Lin Pang, Hongxin Zhao, Linghang Wang

“…The FilmArray Respiratory Panel with multiplex targets for respiratory pathogens has been widely used and verified in clinical trials in special test settings. However, it is necessary to evaluate the panel’s performance at the point of care directly, in nonspecific test settings. …”
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