Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis by Yang Ding, Shengyi Yang, Shasha Fan, Yi Tang, Yan Teng, Xiaohua Tao, Wei Lu

“…Future studies, including random controlled clinical trials, should evaluate the association and mechanisms between serum VD levels and SLE.…”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Future research should focus on planning larger clinical trials with dietary interventions in PD in order to obtain hard evidence for the hypothesized beneficial effects.…”
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Multicenter randomized double-blind placebo-controlled crossover study of the effect of prolonged noisy galvanic vestibular stimulation on posture or gait in vestibulopathy. by Chisato Fujimoto, Takuya Kawahara, Yayoi S Kikkawa, Makoto Kinoshita, Teru Kamogashira, Mineko Oka, Tsukasa Uranaka, Naoya Egami, Kentaro Ichijo, Kayoko Kabaya, Sachiyo Katsumi, Ikumi Takashima, Yoshiharu Yamamoto, Masato Yagi, Tatsuya Yamasoba, Shinichi Iwasaki

“…<h4>Materials and methods</h4>This trial was registered in the Japan Pharmaceutical Information Center Clinical Trials Information registry (jRCT1080224083). …”
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Phytoconstituent analysis, bioactivity, and safety evaluation of various colors of Chrysanthemum morifolium flower extracts for cosmetic application by Angsana Neatpatiparn, Varaporn Buraphacheep Junyaprasert, Krit Thirapanmethee, Veerawat Teeranachaideekul

“…However, further studies, including human clinical trials, are needed to confirm these biological activities and safety profiles.…”
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Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages by Tao Guo, Yukun He, Weijie Ma, Zhisu Liu, Quanyan Liu

“…And the efficacy of SAMe therapy should be further explored in randomized prospective clinical trials.…”
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The Effects of Baclofen for the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Trials by Shujie Li, Shengying Shi, Feng Chen, Jingming Lin

“…We systematically searched randomized controlled trials published prior to November 2013 from PubMed, Medline, Embase, ScienceDirect, ClinicalTrials.gov, and the Cochrane Central Register of Randomized Controlled Trials. …”
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Recent advances in mesenchymal stem cell therapy for multiple sclerosis: clinical applications and challenges by Kamran Sheikhi, Salah Ghaderi, Hassan Firouzi, Sarvenaz Rahimibarghani, Ehsan Shabani, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Aref Yarahmadi

“…It examines preclinical studies and clinical trials evaluating the efficacy, safety, and limitations of MSC therapy in various MS phenotypes. …”
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A scoping review of the contralateral effects of unilateral peripheral stimulation on neuromuscular function. by Shi Zhou, Shuang-Shuang Zhang, Zachary J Crowley-McHattan

“…The findings suggest a need to enhance the awareness of cross-education caused by peripheral stimulation, to help improve the translation of theoretical concepts to clinical practice, and aid in developing well-designed clinical trials to determine the efficacy of cross-education therapies.…”
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Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease by Tianle Chen, Yuanjia Wang, Yanyuan Ma, Karen Marder, Douglas R. Langbehn

“…Accurate estimation of the AAO distribution based on CAG repeat length is important for genetic counseling and the design of clinical trials. In the Cooperative Huntington's Observational Research Trial (COHORT) study, the CAG repeat length is known for the proband participants. …”
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Photobiomodulation Therapy for Neurosensory Disturbances in Orthognathic Surgery Patients: A Systematic Review by Aneta Olszewska, Mateusz Wolny, Julia Kensy, Agnieszka Kotela, Agata Czajka-Jakubowska, Jacek Matys

“…However, the development of standardized treatment protocols and the conduct of larger-scale clinical trials are essential to optimize their clinical application.…”
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Protocol for a Randomized Hybrid Type 2 Trial on the Implementation of Group Problem Management Plus (PM+) for Venezuelan Women Refugees and Migrants in Colombia by Manaswi Sangraula, M. Claire Greene, Diany Castellar, Jean Carlos Flechas de la Hoz, Jennifer Diaz, Valeria Merino, Lucy Miller-Suchet, Maria Cristobal, Ana Maria Chamorro Coneo, Luisa Morales, Marcela Venegas, Abel Guerrero Gonzalez, Marilyn DeLuca, Miguel Uribe, Sara A. Romero, Monica Ferrer, Leslie Snider, Lisa A. Marsch, Zelde Espinel, James M. Shultz, Peter Ventevogel, Brandon A. Kohrt, Camilo Ramirez, Annie Bonz, Ana Maria Trejos Herrera, Adam D. Brown

“…Trials Registry: ClinicalTrials.gov identifier: NCT05477355…”
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Reverse Fragility Index in Plastic Surgery Randomized Controlled Trials by Rodney Ahdoot, BS, Trista M. Benítez, MPH, Chien-Wei Wang, MD, Kevin C. Chung, MD, MS

“…The RFI is a useful measure to complement the P value and examine the neutrality of null clinical trials.…”
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A systematic review of Randomized Controlled Trials about some non-pharmacological interventions for treatment of hypertension: Physical exercise, sodium restriction, weight and al... by Amobi Akonobi, Jawad Khan

“…Original papers and randomized clinical trials, published in English between 1988 and 2010 and regarding hypertensive individuals as participants were included. …”
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Acupuncture for military veterans with posttraumatic stress disorder and related symptoms after combat exposure: Protocol for a scoping review of clinical studies. by Hye-Bin Seung, Jungtae Leem, Hui-Yong Kwak, Chan-Young Kwon, Sang-Ho Kim

“…These results will be helpful for developing disaster site-specific research protocols for future clinical trials on this topic.…”
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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

“…This narrative review underscores the need for continued research into the molecular mechanisms underlying these interactions and suggests future directions for therapeutic development, including clinical trials, biomarker discovery, and combination therapies that synergistically target aging processes.…”
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Novel fusion protein REA induces robust prime protection against tuberculosis in mice by Sintayehu Kebede Gurmessa, Han-Gyu Choi, Yong Woo Back, Zongyou Jiang, Thuy An Pham, Seunga Choi, Hwa-Jung Kim

“…Abstract While many novel candidates for tuberculosis vaccines are presently undergoing pre-clinical or clinical trials, none of them have been able to eliminate infection entirely. …”
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Effect of COVID-19 on Pregnancy and Neonate’s Vital Parameters: A Systematic Review by Anna Charuta, Monika Smuniewska, Zofia Woźniak, Agnieszka Paziewska

“…In order to analyse the available research literature, the Web of Science, Scopus, and PubMed databases were used, in which the search for articles was conducted using terms (“pregnancy,” “coronavirus,” “SARS-CoV-2,” and “newborn”) and using PRISMA (Preferred Reporting Items for Systemic Reviews and Meta-Analysis) guidelines for clinical trials. Meta-analyses and systematic reviews (2022–2023) on symptoms, neonatal course, and risk of COVID-19 infection have been summarized. …”
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The Effect of Long-Term Exercise on the Production of Osteoclastogenic and Antiosteoclastogenic Cytokines by Peripheral Blood Mononuclear Cells and on Serum Markers of Bone Metabol... by J. Kelly Smith, Rhesa Dykes, David S. Chi

“…This trial is registered with Clinical Trials.gov Identifier: NCT02765945.…”
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Reducing the urge to be physically active in patients with anorexia nervosa through virtual reality: protocol for a randomised-controlled feasibility trial by Nina Timmesfeld, Georgios Paslakis, Georg Halbeisen

“…The findings will be published with open access.Trial registration number DRKS00035681, German Clinical Trials Register.…”
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The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis by Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin, Jan A. Plock

“…A trend towards potential promotion of both breast cancer growth and invasion by ADSCs found in basic science studies was indeed not confirmed in clinical trials. Whether experimental findings eventually correlate with or will be predictive of clinical outcomes remains unclear. …”
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