Synbiotics in caries prevention: A scoping review. by Mohammed Nadeem Bijle, Manikandan Ekambaram, Edward C M Lo, Cynthia Kar Yung Yiu

“…No controlled clinical trials or systematic reviews on the role of synbiotics in caries prevention could be identified. …”
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The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells by Faranak Korfi, Hossein Javid, Reza Assaran Darban, Seyed Isaac Hashemy

“…Therefore, this drug might be introduced as a potential candidate for controlling glioblastoma cancer in animal models and clinical trials.…”
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Lecanemab’s Path Forward: Navigating the Future of Alzheimer’s Treatment in Europe Amidst the EMA's Rejection by Alessandro Martorana, Chiara Giuseppina Bonomi, Martina Gaia Di Donna, Caterina Motta

“…The EMA’s refusal underscores the need to address doubts surrounding the real-world effectiveness and safety of such treatments, especially concerning amyloid-related imaging abnormalities (ARIAs), a common side effect observed in clinical trials. The recent approval of lecanemab by the UK's Medicines and Healthcare products Regulatory Agency, despite the National Institute for Health and Care Excellence’s rejection on cost-effectiveness grounds, further fuels the debate on the feasibility of anti-amyloid therapies. …”
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Effect of different regional anaesthesia techniques on postoperative analgesia following percutaneous nephrolithotomy: A systematic review and network meta-analysis by Kun Long, Chengfu Zhou, Jingqiu Liang, Xixi Tang, Zhijian Li, Qi Chen

“…Methods: We searched PubMed, ScienceDirect, ClinicalTrials.gov, MEDLINE, Web of Science, Ovid and EMBASE to identify all relevant randomised controlled trials published up to January 2024. …”
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Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. by Shirley D Wenker, María Isabel Farias, Victoria Gradaschi, Corina Garcia, Juan Beauquis, María Celeste Leal, Carina Ferrari, Xianmin Zeng, Fernando J Pitossi

“…Even though successful transplantation of dopamine-producing cells into the striatum exhibits favourable effects in animal models and clinical trials; transplanted cell survival is low. Since every transplant elicits an inflammatory response which can affect cell survival and differentiation, we aimed to study in vivo and in vitro the impact of the pro-inflammatory environment on human dopaminergic precursors. …”
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Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy: A Meta-Analysis of Randomized Controlled Trials by YinFeng Shen, WenYin Jin

“…Published data of randomized clinical trials (RCTs) comparing the clinically relevant outcomes of PG versus PJ after PD were analyzed. …”
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Exploiting question-answer framework with multi-GRU to detect adverse drug reaction on social media by Jiao-huang Luo, Ai-hua Yang

“…The dilemma arises from the inherent impossibility of conducting a comprehensive evaluation of a drug before its market release, constrained by the limitations in scale and duration of clinical trials. Therefore, the post-marketing detection of ADRs in a timely and accurate manner becomes imperative. …”
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From Molecule to Patient Rehabilitation: The Impact of Transcranial Direct Current Stimulation and Magnetic Stimulation on Stroke—A Narrative Review by Anca Badoiu, Smaranda Ioana Mitran, Bogdan Catalin, Tudor Adrian Balseanu, Aurel Popa-Wagner, Florin Liviu Gherghina, Carmen Valeria Albu, Raluca Elena Sandu

“…Thus, no response or even worsening effects were obtained under certain circumstances both in animal stroke model studies and in clinical trials. Overall, weighing up risks and benefits, the new transcranial electrical and magnetic stimulation techniques can represent effective tools with which to improve the patients’ recovery after stroke, with minimal to no adverse effects. …”
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Therapies with Emerging Evidence of Efficacy: Avotermin for the Improvement of Scarring by Jim Bush, Karen So, Tracey Mason, Nick L. Occleston, Sharon O'Kane, Mark W. J. Ferguson

“…A wide range of non-invasive and invasive techniques have been used in an attempt to improve scarring although robust, prospective clinical trials to support the efficacy of these therapies are lacking. …”
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Anti-Inflammatory and Antimicrobial Effects of Herbal Formulation Called Apo-Taat Using Extended-Spectrum ß-Lactamase-Producing Escherichia coli Isolates by Thanakan Kitnithiprapha, Sumalee Panthong, Intouch Sakpakdeejaroen, Sumalee Kondo

“…Furthermore, safety and clinical trials should be conducted in the future.…”
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Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach by Luc J. W. Evers, Yordan P. Raykov, Tom M. Heskes, Jesse H. Krijthe, Bastiaan R. Bloem, Max A. Little

“…Objective and continuous monitoring of Parkinson’s disease (PD) tremor in free-living conditions could benefit both individual patient care and clinical trials, by overcoming the snapshot nature of clinical assessments. …”
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Safety and Efficacy of Two Trabecular Micro-Bypass Stents as the Sole Procedure in Japanese Patients with Medically Uncontrolled Primary Open-Angle Glaucoma: A Pilot Case Series by Daisuke Shiba, Shingo Hosoda, Saori Yaguchi, Naoki Ozeki, Kenya Yuki, Kazuo Tsubota

“…Implantation of two trabecular micro-bypass stents as the sole procedure in Japanese POAG patients effectively reduced IOP and exhibited a favorable safety profile. Clinical Trials Registration number is UMIN000004002.…”
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Acupuncture for psoriasis: protocol for a systematic review by Lei Wang, Weiming Wang, Haoyu Yang, Nuo Li, Yanping Bai

“…We will also try to obtain literature by manually searching reference lists, conference proceedings and registers of clinical trials (eg, the Meta Register of Controlled Trials and the Chinese Clinical Trial Registry). …”
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A Case of Non-Small Cell Lung Cancer with Possible “Disease Flare” on Nivolumab Treatment by Shotaro Chubachi, Hiroyuki Yasuda, Hidehiro Irie, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima, Tomoko Betsuyaku

“…Background. Recent clinical trials proven the clinically significant efficacy and tolerability of nivolumab, a programmed death 1 (PD-1) inhibitor, in previously treated patients with non-small cell lung cancer (NSCLC). …”
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New Treatments for Bacterial Keratitis by Raymond L. M. Wong, R. A. Gangwani, Lester W. H. Yu, Jimmy S. M. Lai

“…In vitro studies and prospective clinical trials have shown that fourth-generation fluoroquinolones are better than the older generation fluoroquinolones and are as potent as combined fortified antibiotics against common pathogens that cause bacterial keratitis. …”
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Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa: A systematic scoping review. by Solène Thorey, Corinne Blanchet, Sélim Benjamin Guessoum, Marie Rose Moro, Maude Ludot, Emilie Carretier

“…<h4>Introduction</h4>Second-generation antipsychotics (SGAs) are frequently prescribed for the treatment of resistant anorexia nervosa. However, few clinical trials have been conducted so far and no pharmacological treatment has yet been approved by the Food and Drug Administration. …”
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Neonatal Surgery Intensive Care Unit: Hacettepe University Experience by Umit Ayse Tandircioglu, Hasan Tolga Celik, Sule Yigit, Murat Yurdakok

“…The protocol was registered with Clinical Trials.gov identifier NCT04734002. RESULTS: The total number of newborns admitted to the neonatal intensive care unit was 5442. …”
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Assessment of smartphone-based active distraction in association with audioanalgesia for overcoming airotor-related anxiety in children: a randomized controlled trial by Kritika Bali, Radhika Ailawadi, Y. M. Karuna, N. Srikant, Ashwin Rao, P. Anupama Nayak, Charisma Thimmaiah

“…Trial Registration Registered in the Clinical Trials Registry India (CTRI/2024/07/070160) dated 08/07/2024.…”
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Association of CVAI, LAP and SMI with risk of haematological toxicity after immunochemotherapy in patients with DLBCL: a retrospective study by Caifeng Liao, Hurong Lai, Yansong Tu, Ling He, Chuyang Lin, Huaijun Tu, Jian Li

“…Trial registration: This is a retrospective study, and no registration on ClinicalTrials.gov.…”
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<i>Cordyceps militaris</i>-Derived Bioactive Gels: Therapeutic and Anti-Aging Applications in Dermatology by Trung Quang Nguyen, Thinh Van Pham, Yusuf Andriana, Minh Ngoc Truong

“…Emphasis is placed on the necessity of clinical trials and standardization to establish the safety, efficacy, and reproducibility of such applications. …”
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