Perspective of Patient Advocacy Groups on Clinical Research and Outcomes of Their Involvement by Poonam Bagai, Pooja Sharma, Aala Ansari, Nirbhay Singh, Rhea Aggarwal, Durga Chougule, Sonal Sharma, Padam Singh, Manish Kumar Singh, Gargi Singh, Sanjeev Singh

“…Results: Among 185 participants, 97.8% were aware about clinical research/trials and 90.3% understood clinical trials are conducted before any drug reaches market. …”
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Durvalumab, Tremelimumab, and Platinum Chemotherapy in EGFR Mutation–Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE) by Chee Khoon Lee, PhD, Bin-Chi Liao, MD, Shalini Subramaniam, MMed (Clin Epi), Chao-Hua Chiu, MD, Antony J. Mersiades, MMed (Clin Epi), Chao-Chi Ho, MD, PhD, Chris Brown, MBiostats, Chun-Liang Lai, MD, PhD, Brett G.M. Hughes, M.B.B.S. (Hons), Tsung-Ying Yang, MD, PhD, Ken O’Byrne, MD, Yung-Hung Luo, MD, PhD, Sonia Yip, PhD, Ching-Liang Ho, MD, Victoria Bray, PhD, Wu-Chou Su, MD, PhD, Melissa Moore, PhD, Wei-Lien Feng, MS, Ya-Ying Bai, MS, Kate Ford, MHSc, Michelle M. Cummins, PhD, Martin R. Stockler, MSc (Clin Epi), Benjamin J. Solomon, PhD, Thomas John, PhD, James Chih-Hsin Yang, MD, PhD

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A note on the probability structure of a doubly randomized delayed start design by Zhao Yang

“…Y., Li, Y., Liu, Y., Lewin, D., & Lim, P. (2016 On clinical trials with a high placebo response rate. Contemporary Clinical Trials Communications, 2, 34–53. https://doi.org/10.1016/j.conctc.2015.10.002) introduced a new statistical methodology with a conditional probability structure to account for the specific characteristics of the DRDS design. …”
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Options of dyslipidemia treatment at non-alcoholic fatty liver disease by M. V. Mayevskaya, M. A. Morozova

“…Results of numerous experiments and several clinical trials form the basis for phenofibrate administration for NAFLD patients. …”
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Ability of pulse oximetry-derived indices to predict hypotension after spinal anesthesia for cesarean delivery: A systematic review and meta-analysis. by Yuriko Kondo, Eishin Nakamura, Hisashi Noma, Sayuri Shimizu, Takahisa Goto, Takahiro Mihara

“…We searched MEDLINE, Embase, Web of Science, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, ClinicalTrials.gov, European Union Clinical Trials Register, World Health Organization International Clinical Trials Registry Platform, and University Hospital Medical Information Network Clinical Trials Registry databases from inception until June 15, 2023. …”
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Efficacy of Adjunctive Treatments Added to Olanzapine or Clozapine for Weight Control in Patients with Schizophrenia: A Systematic Review and Meta-Analysis by Yun-Jung Choi

“…Fourteen randomized clinical trials were included for systematic review and meta-analysis from 132 potential trials. …”
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Lutein, Zeaxanthin, and meso-Zeaxanthin in the Clinical Management of Eye Disease by Nicole K. Scripsema, Dan-Ning Hu, Richard B. Rosen

“…Subsequently, the effect of xanthophylls in the prevention and treatment of various eye diseases has been examined through epidemiological studies, animal studies, and clinical trials. This paper attempts to review the epidemiological studies and clinical trials investigating the effects of xanthophylls on the incidence and progression of various eye diseases. …”
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Randomised controlled trial to investigate the effectiveness of local oestrogen treatment in postmenopausal women undergoing pelvic organ prolapse surgery (LOTUS): a pilot study to... by Jane Daniels, Lee Middleton, Tina Sara Verghese, Versha Cheed, Lisa Leighton, Pallavi Manish Latthe

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‘Piloting a framework for analysing the public contributions to R&D: new antibiotics in focus’ by Louise Schmidt, Ozren Sehic, Ursula Theuretzbacher, Daniel Fabian, Claudia Wild

“…Information on clinical trials, university spinouts and public funding for SMEs was then gathered from various sources. …”
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FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trial by Laith Alrubaiy, Rachel Cooney, Tariq Iqbal, Mohammed Nabil Quraishi, Susan Manzoor, Christopher Quince, Palak J Trivedi, Andrew D Beggs, Alexandra Vince, Chris Weston, Benjamin Mullish, Sahida Shabir, Nicola Jackson, Anna Rowe, Victoria Homer, Willem van Schaik, Peter Rimmer, Sarah Al-Shakhshir, Arzoo Patel, Derick Gyimah, Miriam Hares, Elena Efstathiou

“…Weblink: Study Details | FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis | ClinicalTrials.gov.…”
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Brain Metastases Research 1990–2010: Pattern of Citation and Systematic Review of Highly Cited Articles by Carsten Nieder, Anca L. Grosu, Minesh P. Mehta

“…Among the 10 most cited articles, 7 reported on randomized clinical trials. Nine covered surgical or radiosurgical approaches and the remaining one a widely adopted prognostic score. …”
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Behavioural components and delivery features of early childhood obesity prevention interventions: intervention coding of studies in the TOPCHILD Collaboration systematic review by Brittany J. Johnson, Paul M. Chadwick, Samantha Pryde, Anna Lene Seidler, Kylie E. Hunter, Mason Aberoumand, Jonathan G. Williams, Hei In Lau, Sol Libesman, Jannik Aagerup, Angie Barba, Louise A. Baur, Samantha Morgillo, Lee Sanders, Sarah Taki, Kylie D. Hesketh, Karen Campbell, Alexandra Manson, Alison Hayes, Angela Webster, Charles Wood, Denise A. O’Connor, Karen Matvienko-Sikar, Kristy Robledo, Lisa Askie, Luke Wolfenden, Rachael Taylor, H. Shonna Yin, Vicki Brown, Alexander Fiks, Alison Ventura, Ata Ghaderi, Barry J. Taylor, Cathleen Stough, Christine Helle, Cristina Palacios, Eliana M. Perrin, Elizabeth Reifsnider, Finn Rasmussen, Ian M. Paul, Jennifer S. Savage, Jessica Thomson, Jinan Banna, Junilla Larsen, Kaumudi Joshipura, Ken K. Ong, Levie Karssen, Li Ming Wen, Márcia Vitolo, Margrethe Røed, Maria Bryant, Maribel Campos Rivera, Mary Jo Messito, Natalia Golova, Nina Cecilie Øverby, Rachel Gross, Rajalakshmi Lakshman, Rebecca Byrne, Russell L. Rothman, Sharleen O’Reilly, Stephanie Anzman-Frasca, Vera Verbestel, Claudio Maffeis, Kayla de la Haye, Sarah-Jeanne Salvy, Seema Mihrshahi, Janani Ramachandran, Paola Seffrin Baratto, Rebecca K. Golley, on behalf of the TOPCHILD Collaboration

“…Methods Annual systematic searches were performed in MEDLINE, Embase, Cochrane (CENTRAL), CINAHL, PsycINFO, and two clinical trial registries, from inception to February 2023. …”
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Mesenchymal Stem Cell-Based Immunomodulation: Properties and Clinical Application by Mengyuan Wang, Quan Yuan, Liang Xie

“…In this review, we will summarize and update the latest research findings and clinical trials on MSC-based immunomodulation.…”
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A survey of obstetric ultrasound uses and priorities for artificial intelligence-assisted obstetric ultrasound in low- and middle-income countries by Amy Sarah Ginsburg, Zylee Liddy, Eren Alkan, Kayla Matcheck, Susanne May

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Mapping the global clinical landscape of stem cell therapies for neurological diseases from 1998 to 2023: an analysis based on the Trialtrove database by Shenzhong Jiang, Xinjie Bao, Chunlong Zhong, Renzhi Wang

“…Based on the Trialtrove database, we retrospectively analyzed 530 clinical trials initiated by the end of 2023.…”
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Update on the Treatment of Metastatic Urothelial Carcinoma by Nedal Bukhari, Humaid O. Al-Shamsi, Faisal Azam

“…This review reports key findings from the clinical trials especially highlighting the importance of PD-1 and PD-L1 inhibitors in the treatment of bladder/urothelial carcinomas.…”
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Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review by Aakriti Saini, Amandeep Kaur, Sidhartha Sharma, Vijay Kumar, Amrita Chawla, Ajay Logani

“…Electronic searches were performed in PubMed, Embase, Web of Science, International Clinical Trials Registry Platform, and ClinicalTrials.gov for English language articles until July 2021. …”
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Polatuzumab vedotin combined with bendamustine and rituximab for relapsed/refractory diffuse large B-cell lymphoma: A systematic review protocol. by Mohammadreza Eslami, Mahdi Mehrabi, Mehrdad Payandeh, Fakhredin Saba

“…A comprehensive search will be conducted across databases such as Medline/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE, ProQuest, EU Clinical Trials Register, WHO International Clinical Trials Registry Platform (ICTRP), and ClinicalTrials.gov from the January 2000 to April 2024. …”
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Effects of maternal positions in electronic fetal monitoring: a randomised controlled trial by Tuğba Yilmaz Esencan, Ayça Demir Yildirim, Ebru Sağiroğlu

“…Clinical Study Registration Since our research constituted a randomized controlled study, it was registered on the ClinicalTrials.gov website under ClinicalTrials ID No. …”
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TZDs and Bone: A Review of the Recent Clinical Evidence by Ann V. Schwartz

“…Increased fracture risk in women, but not men, was reported for both TZDs, based on analyses of adverse event reports from clinical trials. In short-term clinical trials in women, both TZDs caused more rapid bone loss. …”
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