Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial by Basharat Hussain, Basharat Hussain, Muhammad Tahir Khalily, Muhammad Tahir Khalily, Ahmed Waqas, Atif Rahman, Ioannis Angelakis, Anum Nisar, Sabir Zaman, Tanveer Akhtar

“…Participants reported that this cultural alignment made the coping strategies more relatable and easier to adopt, contributing to improvements in both their mental health and somatic symptoms.Clinical Trial Registrationhttps://clinicaltrials.gov/ct2/show/NCT04981522, identifier NCT04981522.…”
Get full text

Effects of the MyBFF@school obesity intervention program with nutrition education intervention on nutrition knowledge and attitude of secondary schoolchildren: a cluster randomized... by Rusidah Selamat, Junidah Raib, Nur Azlina Abdul Aziz, Norlida Zulkafly, Ainan Nasrina Ismail, W Nurul Ashikin W Mohamad, Ainol Aizuddin Zulkiply, Muhammad Yazid Jalaludin, Fuziah Md. Zain, Zahari Ishak, Abqariyah Yahya, Abdul Halim Mokhtar

“…Trial registration Clinical trial number: NCT04155255, November 7, 2019 (Retrospective registered). …”
Get full text

Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

“…., Montreal, QC, Canada) in children receiving INH daily at 10 mg/kg in a single-center, open-label, non-randomized, phase IIa clinical trial (EudraCT Number: 2016-002000-31) in Barcelona (Spain). …”
Get full text

Subjective Taste and Smell Changes in Conjunction with Anxiety and Depression Are Associated with Symptoms in Patients with Functional Constipation and Irritable Bowel Syndrome by Jie Liu, Chaolan Lv, Dandan Wu, Ying Wang, Chenyu Sun, Ce Cheng, Yue Yu

“…This study protocol was registered on the Chinese Clinical Trial Registry (No. ChiCTR-2100044643). Results. …”
Get full text

Dietary intake of tomato and lycopene, blood levels of lycopene, and risk of total and specific cancers in adults: a systematic review and dose–response meta-analysis of prospectiv... by Arghavan Balali, Kimia Fathzadeh, Gholamreza Askari, Omid Sadeghi, Omid Sadeghi

“…Also, an inverse association was observed between blood lycopene levels and lung cancer mortality (Pooled RR: 0.65, 95% CI: 0.45–0.94, I2 = 0, p = 0.022).ConclusionOur findings show that dietary intake and blood levels of lycopene are associated with a lower risk of cancer and death due to cancer.Clinical trial registrationCRD42023432400.…”
Get full text

Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells agains... by Weiting Liao, Ge Gao, Xia He, Pei Shu, Qizhi Ma, Benxia Zhang, Diyuan Qin, Yongsheng Wang

Get full text

Real-world study of phakic refractive lens for correction of high myopia by An-Peng Pan, Xu Shao, Yi-Ke Li, Zi-Yue Li, Qiong Yan, Wei-Yang Sun, A-Yong Yu

“…Trail registration: Chinese Clinical Trial Registry, ChiCTR2100043600. Registered on 23 February 2021, https://www.chictr.org.cn/showproj.html?…”
Get full text

Evaluating Whether Nonimmersion Virtual Reality Simulation Training Improves Nursing Competency in Isolation Wards: Randomized Controlled Trial by Dandan Zhang, MuLi Fu, Jianzhong Zhang, Yuxuan Li, Li Chen, Yong-Jun Chen, Zhefeng Zhong, Yin-Ping Zhang

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR240083155; https://www.chictr.org.cn/hvshowproject.html?…”
Get full text

Impact of school salad bars on fruit and vegetable selection, intake, and waste in Mid-Atlantic elementary schools by Melanie K. Bean, Suzanne E. Mazzeo, Lilian de Jonge, Laura Thornton, Hollie Raynor, Ashley Mendoza, Sarah Farthing, Bonnie Moore

“…Trial registration This investigation reports results of a systematic evaluation of school salad bars and does not meet criteria for a clinical trial, yet was retrospectively registered (10/28/22) in clinicaltrials.gov (NCT05605483) as an observational study.…”
Get full text

Ten Machine Learning Models for Predicting Preoperative and Postoperative Coagulopathy in Patients With Trauma: Multicenter Cohort Study by Xiaojuan Xiong, Hong Fu, Bo Xu, Wang Wei, Mi Zhou, Peng Hu, Yunqin Ren, Qingxiang Mao

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR2300078097; https://www.chictr.org.cn/showproj.html?…”
Get full text

A novel gene signature for predicting outcome in colorectal cancer patients based on tumor cell-endothelial cell interaction via single-cell sequencing and machine learning by Lina Pang, Qingxia Sun, Wenyue Wang, Mingjie Song, Ying Wu, Xin Shi, Xiaonan Shi

Get full text

ApoB/ApoA-Ι is associated with major cardiovascular events and readmission risk of patients after percutaneous coronary intervention in one year by Jie Zhang, Mengyu Liu, Ju Gao, Xiaowen Tian, Yaru Song, Haibei Zhang, Peng Zhao

“…Trial registration Chinese clinical trial registry: No.ChiCTR22000597-23.…”
Get full text

Cardiomeds, an mHealth App for Self-Management to Support Swiss Patients With Heart Failure: 2-Stage Mixed Methods Usability Study by Lisa Simioni, Elena Tessitore, Hamdi Hagberg, Aurélie Schneider-Paccot, Katherine Blondon, Liliane Gschwind, Philippe Meyer, Frederic Ehrler

“…The app will be further tested in a randomized clinical trial (2022-00731) after acute HF hospitalization to assess its impact on patients’ knowledge about HF, self-care, and quality of life.…”
Get full text

How to build a framework to establish a patient research partner network in rheumatology research: a report of a 2-year implementation project by Maarten de Wit, Oliver Distler, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Muriel Elhai, Rucsandra Dobrota, Adrian Ciurea, Caroline Ospelt, Raphael Micheroli, Dania Diem, Stefan Dudli, Kristina Buerki, Stacey Grealis, Melpomeni Toitou, Silke Ludwig, Chantal Britt, Florian Klett, Isabelle Steeb, Tanja Maletic, Andreas Eisenring, Penelope Jane Timpert-Argust, Eva Camarillo-Retamosa

Get full text

Correlation between Therapeutic Efficacy of CD34+ Cell Treatment and Directed In Vivo Angiogenesis in Patients with End-Stage Diffuse Coronary Artery Disease by Tien-Hung Huang, Cheuk-Kwan Sun, Yi-Ling Chen, Pei-Hsun Sung, Chi-Hsiang Chu, Mel S. Lee, Yuan-Ping Lin, Hon-Kan Yip, Fan-Yen Lee

Get full text

The biomechanical effects of treating double-segment lumbar degenerative diseases with unilateral fixation through interlaminar fenestration interbody fusion surgery: a three-dimen... by Kai-Kai Feng, Xiao-Bing Xiang, Cheng-Peng Li, Kai-Yin Gao, Wei-Wei Zhang, Zhen-Yu Nie, Wen-Xin Liao, Dong Zhao, Guang-Ru Cao

“…This provides some biomechanical evidence for selecting surgical approaches for elderly patients who cannot tolerate long surgeries, suggesting that two-segment unilateral fixation may be advisable. Clinical trial number Not applicable.…”
Get full text

The association between neighborhood social vulnerability and community-based rehabilitation after stroke by Shuqi Zhang, Elizabeth R. Mormer, Anna M. Johnson, Cheryl D. Bushnell, Pamela W. Duncan, Fang Wen, Shweta Pathak, Amy M. Pastva, Janet K. Freburger, Sara B. Jones Berkeley

“…Future studies should evaluate potential mechanisms for these findings and further identify both patient and community factors that may inform strategies to improve rehabilitation use. Clinical Trial Number https://www.clinicaltrials.gov/ NCT02588664 [registration date: 2015–10-23].…”
Get full text

Optimizing transcutaneous spinal stimulation: excitability of evoked spinal reflexes is dependent on electrode montage by Kelly Lynn Thatcher, Karen Emily Nielsen, Evan Blake Sandler, Oliver John Daliet, Jennifer Ann Iddings, Edelle Carmen Field-Fote

“…Our findings optimize electrode placement for interventional TSS and PRM reflex assessments. Clinical Trial Number: NCT04243044.…”
Get full text

Identification of EARS2 as a Potential Biomarker with Diagnostic, Prognostic, and Therapeutic Implications in Colorectal Cancer by Wang L, Deng X, Tang J, Gong Y, Bu S, Li Z, Liao B, Ding Y, Dai T, Liao Y, Li Y

“…Ling Wang,1,2,* Xuemei Deng,1,* Jiaxi Tang,3 Yi Gong,2 Shaojin Bu,4 Zuli Li,1 Bin Liao,2 Yao Ding,2 Tingting Dai,1,5 Yong Liao,1 Yongsheng Li2,6 1Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Phase I Clinical Trial Ward, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China; 3Department of Anesthesiology, Chongqing University Cancer Hospital, Chongqing, China; 4Department of Anesthesiology, Fengdu People’s Hospital, Chongqing, People’s Republic of China; 5Department of Medical Oncology, Chongqing University Fuling Hospital, Chongqing, China; 6Department of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yong Liao, Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, NO. 288 Chayuan Astronomy Avenue, Nanan District, Chongqing, 401336, People’s Republic of China, Email yongliao@cqmu.edu.cn Yongsheng Li, Department of Medical Oncology, Chongqing University Cancer Hospital, No. 181 hanyu Road, Shapingba District, Chongqing, 400030, People’s Republic of China, Email yongshengli2005@163.comPurpose: Colorectal cancer (CRC) is a prevalent malignancy, and lactate metabolism significantly influences tumorigenesis and progression. …”
Get full text

The effect of pressurized intraperitoneal aerosolized chemotherapy on the surgical treatment outcomes of ovarian cancer with peritoneal carcinomatosis by A. S. Dzasochov, A. A. Kostin, V. L. Astashov, A. B. Turiev, A. D. Uskov, M. A. Andreeva

“…These phenomena didn’t require additional medical interventions, didn’t increase the duration of hospitalization and didn’t lead to the exclusion of patients from the clinical trial protocol.Conclusion. The use of the PIPAC technique as an additional method of standard regional treatment has demonstrated an improvement in the results of treatment of newly diagnosed ovarian cancer with peritoneal carcinomatosis. …”
Get full text