An exploratory analysis of differences in serum protein expression by sex in patients with systemic sclerosis associated interstitial lung disease by Giuliana Cerro-Chiang, Matthew Ayres, Alejandro Rivas, Sarah J. Parker, Mitra Mastali, Peter Chen, Jennifer E. Van Eyk, Paul J. Wolters, Francesco Boin, Tanzira Zaman

“…These proteins could influence disease progression and treatment response and underscore the importance of personalized therapeutic strategies and further research into sex-related molecular pathways in SSc-ILD. Clinical trial number Not applicable.…”
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The Use of Social Network in Daily Pediatric Practice and Education: Turkish Pediatric Atelier by Erdem Gönüllü, Ahmet Soysal, İlkay Can, Ercan Tutak, Turan Tunç, İsmail Yıldız, Osman Yeşilbaş, Naci Öner, Ali Anarat, Feryal Gün Soysal, Cengiz Bayram, Mehmet Cihan Balcı, Emine Betül Tavil, Teoman Akçay, Metin Karaböcüoğlu

“…We think that the development of technology and artificial intelligence may lead to the usage of on-line platforms or systems in clinical medical practice. Clinical Trial Registration (if any). Registry name, registration number, web link to study on registry, and data sharing statement.…”
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Various endurance training intensities improve GFR and Up-regulate AQP2/GSK3β in lithium-induced nephropathic rats by Shadan Saberi, Mohammad Amin Rajizadeh, Mohammad Khaksari, Azadeh Saber, Mohammad Akhbari, Soheil Aminizadeh, Forouzan Rafie

“…These findings suggest that tailored exercise regimens could be beneficial for patients undergoing long-term lithium therapy to prevent renal damage. Clinical trial number Not applicable. Graphical Abstract…”
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Effect of different restorative design and materials on stress distribution in cracked teeth: a finite element analysis study by Ting Liu, Yinghao Huang, Yue Li, Jiali Meng, Yajing Liu, Yuan Wei, Yequan Huang, Qian Zhou, Weidong Yang, Fuhua Yan, Xiang Wang, Yanan Zhu

“…Trial registration A protocol was specified and registered with the Chinese Clinical Trial Registry (ChiCTR) on 2022–04-12 (registration number: ChiCTR2200058630).…”
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Risk factors for growth retardation in children with juvenile idiopathic arthritis: a case-control study by Ying Zhang, Liping Song, Weihu Ma, Ye Wang, Peipei Wang, Xiaolin Zhang, Zhe Zhang, Yuan Zhang, Qianhui Yu, Yang Yu, Lin Zhang

“…While each of these factors demonstrates moderate predictive value individually, their combined consideration significantly improves predictive accuracy. Clinical trial number Not applicable.…”
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Multimodal data-based longitudinal prognostic model for predicting atrial fibrillation recurrence after catheter ablation in patients with patent foramen ovale and paroxysmal atria... by Shoupeng Duan, Xujun Li, Jun Wang, Yuhong Wang, Tianyou Xu, Fuding Guo, Yijun Wang, Lingpeng Song, Zeyan Li, Xiaomeng Yang, Xiaoyu Shi, Hengyang Liu, Liping Zhou, Yueyi Wang, Hong Jiang, Lilei Yu

“…Trial registration: This trial was registered in the Chinese Clinical Trial Registry. (ChiCTR2300072320). Graphical Abstract…”
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Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial by Hiroyuki Ase, Kaoru Honaga, Mami Tani, Tomokazu Takakura, Futoshi Wada, Yuhei Murakami, Reina Isayama, Akira Tanuma, Toshiyuki Fujiwara

“…Trial registration: This study was registered in the University Hospital Medical Information Network (UMIN) Clinical Trial Registry in Japan (Unique Identifier: UMIN000038469) on November 1, 2019; https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?…”
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Association between clinical-biological characteristics of Klebsiella pneumoniae and 28-day mortality in patients with bloodstream infection by Xiaofeng Yu, Yi Zhao, Xiao Sun, Jiahui Luan, Haiyan Wang, Tianyu Sun, Tongtong Lin, Xia Zhou, Wei Yang, Ziguang Deng, Bo Liu, Hongyun Cao

“…It may facilitate the clinical management of patients with bloodstream infection (BSI) caused by hypervirulent KP strains, especially those with rfbA/B/D genes. Clinical trial number Not applicable…”
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Brief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors by Alissa J. Cooper, MD, Andrea Arfe, PhD, Biagio Ricciuti, MD, Andréanne Gagné, MD, PhD, Lynette M. Sholl, MD, Alessandro Di Federico, MD, Mark M. Awad, MD, PhD, Mihaela Aldea, MD, PhD, Maria Rosa Ghigna, MD, Miruna Grecea, MD, Phoebe Clark, MS, Jamie E. Chaft, MD, Mark G. Kris, MD, Gregory J. Riely, MD, Charles M. Rudin, MD, PhD, Ibiayi Dagogo-Jack, MD, Mari Mino-Kenudson, MD, Lingzhi Hong, MD, PhD, Neda Kalhor, MD, Natalie Vokes, MD, Anita Bowman, MS, Soo-Ryum Yang, MD, Natasha Rekhtman, MD, PhD, Adam J. Schoenfeld, MD

“…Prospective clinical studies are urgently needed to identify better therapeutic approaches to treat this aggressive malignancy, and this analysis may serve as a benchmark for future clinical trial design.…”
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Seasonal fluctuation of total water intake and hydration status among young men and women: a prospective cohort study by Jianfen Zhang, Jianfen Zhang, Na Zhang, Na Zhang, Junbo Lu, Junbo Lu, Shufang Liu, Yongwei Lin, Guansheng Ma, Guansheng Ma

“…Men need to pay more attention than women to maintain optimal hydration status.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?…”
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The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…The clinical implication of elevated LCN2 and its variants post-exercise on satiety and energy regulation, as well as the mechanisms involved warrant further investigation. Clinical trial registration: www.anzctr.org.au , ACTRN12615000755538.…”
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Preoperative Altered Spontaneous Brain Activity and Functional Connectivity Were Independent Risk Factors for Delayed Neurocognitive Recovery in Older Adults Undergoing Noncardiac... by Zhaoshun Jiang, Xixue Zhang, Yating Lv, Xiaodong Zheng, Huibiao Zhang, Xuelin Zhang, Chongyi Jiang, Guangwu Lin, Weidong Gu

“…This trial is registered with Chinese Clinical Trial Registry ChiCTR-DCD-15006096.…”
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Disproportionality analysis of upadacitinib-related adverse events in inflammatory bowel disease using the FDA adverse event reporting system by Shiyi Wang, Xiaojian Wang, Jing Ding, Xudong Zhang, Hongmei Zhu, Yihong Fan, Changbo Sun

“…The most commonly reported AEs were acne, product residue present, haematochezia, frequent bowel movements, flatulence, blood cholesterol increased, aligning with clinical trial outcomes. Notably, significant but unexpected AEs, such as rosacea, proctalgia, polyp, were also reported. …”
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Diffuseness of coronary artery disease impacts on immediate hemodynamic and predicted clinical outcomes by Shigetaka Kageyama, Pruthvi Chenniganahosahalli Revaiah, Tsai Tsung-Ying, Kotaro Miyashita, Akihiro Tobe, Neil O’Leary, Johan H. C. Reiber, Shengxian Tu, Azfar Zaman, Manel Sabaté, Helge Möllmann, Faisal Sharif, Julien Lemoine, Adrian Wlodarczak, Scot Garg, Yoshinobu Onuma, Patrick W. Serruys

“…A pre-procedure physiological pattern of diffuse CAD is an independent determinant of an unfavourable immediate hemodynamic outcome post-PCI, and detrimentally affects the predicted 2-year VOCE. Clinical Trial Registration URL: https://www.clinicaltrials.gov/ct2/show/NCT04390672 Unique Identifier: NCT04390672 (registration date 15/05/2020)…”
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Young, Empowered & strong (YES): a study protocol paper for a randomized controlled trial of an mHealth symptom monitoring and self-management intervention for adolescent and young... by Kate E Dibble, Shoshana M Rosenberg, Craig Snow, Gregory J Kirkner, Nabihah Tayob, Magnolia Contreras, Noel D Roma, Cecilia R DeGraffinreid, Timiya S Nolan, Dawn L Hershman, Michelle Naughton, Ann H Partridge

“…Secondary outcomes include patient reported AYA concerns/needs, emotional symptoms, general health, physical symptoms, and health behaviors, Discussion Study findings will provide valuable insight into the ability of the YES digital health intervention to address symptoms and concerns of AYA BC survivors and assist them to track and self-manage their own symptoms, concerns, and needs related to their cancer outside of the clinic. Trial registration Clinicaltrials.gov, NCT04906200, registered May 13, 2021.…”
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Decreased Levels of Insulin-Regulated Aminopeptidase (IRAP) in Gestational Diabetes Mellitus: A Prospective Cohort Study by Osman Köse, Koray Gök, Elif Köse, Sezen Irmak Gözükara, Abdullah Tüten, Mehmet Sühha Bostancı

“…These findings suggest that low serum IRAP level could be a novel biomarker for the prediction of GDM. Clinical Trial registration: The study has been registered on https://classic.clinicaltrials.gov/ (registration number: NCT06716320).…”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…This trial aims to develop and evaluate the effectiveness of a social participation-focused virtual reality (SP-VR) intervention on the physical, psychological and social outcomes of community-dwelling stroke survivors with physical disabilities.Methods and analysis A two-arm randomised, controlled, assessor-blind clinical trial will be conducted with 250 stroke survivor–caregiver dyads recruited from three acute and one rehabilitation hospitals, and three stroke nurse-led clinics. …”
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Evaluation of naturally occurring IgG anti-Vi antibody titers as predictors and correlates of typhoid fever in Dhaka, Bangladesh by Farhana Khanam, Natasha Y. Rickett, Faisal Ahmmed, Md Taufiqul Islam, Cecilia Kathure Mbae, Justin Im, Asma Binte Aziz, Beatrice Ongadi, Fahima Chowdhury, Ashraful Islam Khan, Afroza Akter, Md Golam Firoj, Sadia Isfat Ara Rahman, Kassa Haile, Se Eun Park, Martin Bundi Mwebia, Moses Mwangi, Benjamin Ngugi, Meseret Gebre Behute, Kelvin Kering, Suneth Agampodi, Suman Kanungo, Xinxue Liu, Andrew J. Pollard, K. Zaman, Deok Ryun Kim, Samuel Kariuki, Firdausi Qadri, John D. Clemens

“…Future research should explore these possibilities. Clinical trial number Not applicable.…”
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Risk Factors Associated with Cardiac Autonomic Modulation in Obese Individuals by Camila Oliveira, Erika Aparecida Silveira, Lorena Rosa, Annelisa Santos, Ana Paula Rodrigues, Carolina Mendonça, Lucas Silva, Paulo Gentil, Ana Cristina Rebelo

“…The present study is a cutout of a randomized clinical trial “Effect of nutritional intervention and olive oil in severe obesity” (DieTBra Trial), where the baseline data were analyzed. …”
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A bibliometric analysis of 30 years of research on transarterial radioembolization (TARE) for hepatocellular carcinoma by Tongyao Hu, Tongyao Hu, Qifan Xu, Qifan Xu, Guorong Jia, Tao Wang, Changjing Zuo

“…The keywords were classified into three clusters: 90Y microspheres for TARE, Basic research on TARE, and Clinical trial of TARE for HCC. Furthermore, we identified the most frequently cited keywords with strong citation bursts since 2020 were “multicenter,” “overall survival” and “PET/CT.”ConclusionOur study employed a bibliometric approach to achieve the visualization research on TARE for HCC, and further revealed the trends and frontiers of TARE research, providing valuable information for researchers to identify the critical and persistent challenges and select potential partners in related area. …”
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