First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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Experiences of working as a clinical nurse while pregnant during the coronavirus disease-2019 pandemic: a qualitative study by Lin Ye Wu, Wing Fai Yeung, Yao Lin Pei, Ling Xi Chen, Meng Qi Li, Jia Yin Ruan

“…Moreover, research on moral stigma and bullying in nursing during pregnancy deserves further exploration. Clinical trial number Not applicable.…”
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C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation by Yongfeng Hu, Shaoqiang Li, Yunhui Hong, Dongxian Peng

“…It is crucial for cellular functions and inflammation, with future studies aiming to leverage this for novel preeclampsia treatments. Clinical trial Not applicable.…”
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Association between the triglyceride glucose body mass index and asthma: evidence from NHANES 2011–2018 by Sijia Yu, Shiping Wu, Shouxin Wei

“…These results suggest that TyG-BMI has the potential to be used as an indicator to monitor the prevalence of asthma, but further longitudinal studies are needed to confirm causality and to assess its utility in the management of long-term comorbidities. Clinical trial number Not applicable.…”
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Prevalence of hepatitis B virus and associated factors among blood donors in Hossana blood bank catchment area, Southern Ethiopia by Mesfin Menza Jaldo, Mhireteab WoldeYohannes Joffe, Eyasu Samuel Zemedkun

“…Though post-donation counseling is important for the control and prevention of hepatitis b virus infection, it has been neglected since the establishment of the blood bank we strongly recommend counseling regular donors. Clinical trial number Not applicable.…”
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Therapeutic alliance during trauma focused treatment in adolescent and young adult patients with PTSD by Anne Grass, Rita Rosner, Angelina Ciner, Babette Renneberg, Regina Steil

“…Trial registration The trial was registered at the German Clinical Trial Registry, DRKS00004787, 18 March 2013, https://www.drks.de/DRKS00004787 .…”
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The efficacy of hypothermia combined with thrombolysis or mechanical thrombectomy on acute ischemic stroke: a systematic review and meta-analysis by Dan Wang, Dan Yan, Mingmin Yan, Hao Tian, Haiwei Jiang, Bifeng Zhu, Yu Chen, Tao Peng, Yue Wan

“…The primary objective of the study was to evaluate the effectiveness and safety of hypothermia by combining reperfusion therapy in acute ischemic stroke patients.MethodsA systematic search was performed in PubMed, EMBASE, Cochrane Library, and the Clinical Trial Registries on articles published until May 2024. …”
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Oral health status, behavior and impact profile among naval personnel in the Malaysian naval armed forces by Nik Madihah Nik Azis, Raja Noreihan Raja Abdullah, Mohamad Nur Adzmi Mohamad Ayub, Badiah Baharin

“…These findings highlight the need for tailored oral health interventions within the naval setting to enhance deployment readiness, improve oral health outcomes, and elevate the quality of life for naval personnel. Clinical trial number Not applicable.…”
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Implant Stability Changes for Nonsubmerged and Submerged Protocols for a Single Implant Mandibular Overdenture Using Ball Attachment by Ahmed Salah, Karim Foda, Mohamed Farouk Abdalla, Marwa Abdel Aal, Amr Naguib, Nouran Abdel Nabi

“…The scope of this clinical trial focused only on results of the ball attachment. …”
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Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications by Shinji Uemoto, Kazue Ozawa, Hiroto Egawa, Yasutsugu Takada, Hiroshi Sato, Satoshi Teramukai, Mureo Kasahara, Kohei Ogawa, Masako Ono, Kenji Takai, Masanori Fukushima, Kayo Inaba, Koichi Tanaka

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Reflection to enhance dental students´ awareness of and comfort with uncertainty – an experimental study by Joséphine Brodén, Helena Fransson, Niklas Vareman, Maria Pigg

“…There is a need for further research to better understand students’ and teachers’ perception and attitudes to uncertainty and its effective management. Clinical trial number Not applicable.…”
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Combined effects of reflexology massage and respiratory relaxation on pain following chest tube removal in heart surgery patients by Zainab Bahramian, Majid Kazemi, Reza Vazirinejad, Hadi Hasani

“…Methods This was a double-blind randomized clinical trial performed on 140 patients who underwent heart surgery and had a chest tube in Shiraz, Iran. …”
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Everyday life and boredom of people living with dementia in residential long-term care: a merged methods study by Doris Gebhard, Julia I. Frank

“…Person-centred dementia care provides a valuable intervention strategy to meet this requirement. Clinical trial number Not applicable.…”
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Bupivacaine–fentanyl isobaric spinal anesthesia reduces the risk of ICU admission in elderly patients undergoing lower limb orthopedic surgery by Wenxun Liu, Shuzhen Bao, Jiaxin Chen, Yan Li, Yinghua Gu, Qingshan Ye, Kerong Hai

“…Trial registration: This study has been registered in the Chinese Clinical Trial Registry (ChiCTR2000033411).…”
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Immunogenicity and safety of the MF59-adjuvanted seasonal influenza vaccine in non-elderly adults: A systematic review and meta-analysis. by Alexander Domnich, Carlo-Simone Trombetta, Elettra Fallani, Marco Salvatore

“…<h4>Methods</h4>A systematic literature review was conducted according to the available guidelines and studies were searched in MEDLINE, Biological Abstracts, Web of Science, Cochrane Library and clinical trial registries. Studies on absolute and relative immunogenicity, efficacy, effectiveness, and safety of aTIV/aQIV in non-elderly adults (<65 years) were potentially eligible. …”
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Benefit from regular versus leakage-related exchange of voice prostheses in patients post-laryngectomy considering complication rates and patient satisfaction feedback—a randomized... by Michał Żurek, Małgorzata Czesak, Daniel Majszyk, Anna Rzepakowska

“…The number of replacements (NNTs) that should be performed in the REA scheme to prevent one complication over the LEA scheme is 721.ConclusionThe replacement of regular voice prostheses improved the overall complication rate over the scheme based on leakage demand; however, it did not yield superior benefits in terms of patient satisfaction or economic aspects.Clinical Trial Registrationhttps://clinicaltrials.gov/study/NCT04268459, identifier NCT04268459.…”
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Assessing the relationship between nursing process competency and work environment among clinical nurses: a cross-sectional correlational study by Reza Nemati-Vakilabad, Ehsan Kamalifar, Mobina Jamshidinia, Alireza Mirzaei

“…Additionally, targeted training programs should be provided to focus on the nursing process and skills enhancement, thereby boosting both confidence and competency. Clinical trial number Not applicable.…”
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Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis by Gaiyan Li, Yu Cheng, Shanshan Ding, Qianyun Zheng, Lanqiong Kuang, Ying Zhang, Ying Zhou

“…Conclusion In conclusion, 6 feature genes (HSPA8, NCF2, FOS, KLF4, THBS1, and HSPA1A) related to OS were mined by bioinformatics analysis, which might provide a new insights into the evaluation and treatment of IS. Clinical trial number: Not applicable.…”
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Persistence with Early-Line Abatacept versus Tumor Necrosis Factor-Inhibitors for Rheumatoid Arthritis Complicated by Poor Prognostic Factors by Xue Han, Francis Lobo, Michael S. Broder, Eunice Chang, Sarah N. Gibbs, David J. Ridley, Irina Yermilov

“…Gathering data on treatment patterns outside of a clinical trial setting can provide useful context for clinicians. …”
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Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

“…It can be further developed in clinical studies for the unmet medical needs in management of CVDs and overcome the pharmacogenomic limitations of Clopidogrel.Trial registration number Clinical Trial Registry-India URL: http://ctri.nic.in. …”
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