Comparative assessment of a virtual performance measure with self-report and performance-based outcomes in patients with hip osteoarthritis by Helen Razmjou, Suzanne Denis, Susan Robarts, Amy Wainwright, Patricia Dickson, Ania Roszkowski, John Murnaghan

“…Digitally based outcome measures have the potential of enhancing remote measurement of functional difficulties in specific situations. Clinical trial number Not applicable.…”
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Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy by Xuebiao Wei, Wenqiang Jiang, Zhonghua Wang, Yichen Li, Yuanwen Jing, Yongli Han, Linqiang Huang, Shenglong Chen

“…Through the regulatory loop of PTEN/AKT/FOXO1/MAF1, CUL2 initiated the gradual downregulation of MAF1, which subsequently regulated polymerase III (Pol III)-dependent transcription and played essential roles in cell apoptosis in SAE. Clinical trial number: not applicable. Graphical Abstract…”
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FTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder by Li Ling, Wei Wei, Li Lin, Li Ke, Ye Chen, Li Ning, Wang Yu, Zhang Xin, Yang Rong, Zhang Xueying, Cui Jiaqu, Chen Qiyi, Qin Huanlong, Du Yasong, Zhao Xiaoxin, Lu Jubao, Lv Xiaoqiong, Ma Chunlian, Chen Shidong, Kuang Guifang, Zhao Dongmei, Fang Shuanfeng, Zhang Xujing, Yang Binrang, Wang Yanxia, Yuan Song, Zhou Xiang, Zhang Beihua, Jiang Lin, Ji Hong, Yan Yinmei, Yan Peihua, Huang Linsheng, Zhang Shaoyi, Ma Chenhuan, Miao Yun, Ling Wenqi, Geng Bojing, Feng Xueying, Li Huilin, Liu Liyan, Wu Weijia, Li Dexin, Jiang Qianru

“…The secondary objective focuses on the clinical efficacy and safety of FMT, including its improvement of the clinical response and metabonomics.Ethics and dissemination Ethical approval was obtained from the hospital Ethics Committee of each Faecal Transfer for ASD China Multicenter Trial Working Group. The ongoing FMT clinical trial is intended to support the approval of the new technology and its administration. …”
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Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study by Fumin Xu, Xiao Chen, Chenwenya Li, Jing Liu, Qiu Qiu, Mi He, Jingjing Xiao, Zhihui Liu, Bingjun Ji, Dongfeng Chen, Kaijun Liu

“…The study is registered with the China Clinical Trial Registry (Identifier: ChiCTR1800016079).…”
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Functional and structural connectivity of the subregions of the amygdala in ADHD children with or without ODD by Zhao-Min Wu, Peng Wang, Xue-Chun Liu, Qing-Chao Zhou, Xiao-Lan Cao, Li Sun, Lu Liu, Qing-Jiu Cao, Li Yang, Yu-Feng Wang, Ying Qian, Bin-Rang Yang

“…Conclusions Altered structural and functional connectivity of the subregions of the amygdala in children with ADHD compared with their healthy counterparts were respectively associated with ADHD-related behavioral and emotional problems. Clinical trial number : not applicable.…”
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An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f... by Ana Paula Taboada Sobral, Elaine Marcilio Santos, Marcela Leticia Leal Gonçalves, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Elza Padilha Ferri, Juliana Maria Altavista Sagretti Gallo, Thais Gimenez, José Carlos Pettorossi Imparato

“…Thus, this project aims to evaluate the effectiveness of restorative treatment of anterior primary teeth with monochromatic composite resin in single insertion through polyvinyl crowns, after selective removal of carious tissue compared with the effectiveness of conventional restoration.Methods and analysis This study proposes to conduct a randomised clinical trial, composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified International Caries Detection and Assessment System (ICDAS) C+ score (active and extensive stage caries: ICDAS 5 and 6), with involvement of more than two surfaces. …”
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Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families by Bin Mao, Xiaoling Cai, Na Lin, Yulin Jiang, Na Hao, Yifang Dai, Danhua Guo, Deqin He, Huili Xue, Lingji Chen, Qianqian He, Min Zhang, Meihuan Chen, Hailong Huang, Liangpu Xu

“…Molecular analysis is highly beneficial for the precise diagnosis, genetic counseling and prenatal diagnosis of families suspected of having genetic muscular disorders. Clinical trial number Not applicable.…”
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Brain Functional Network in Chronic Asymptomatic Carotid Artery Stenosis and Occlusion: Changes and Compensation by Shihao He, Ziqi Liu, Zongsheng Xu, Ran Duan, Li Yuan, Chu Xiao, Zhe Yi, Rong Wang

“…This trial is registered with Clinical Trial Registration-URL http://www.chictr.org.cn and Unique identifier ChiCTR1900023610.…”
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Intense Pulsed Light Therapy with Optimal Pulse Technology as an Adjunct Therapy for Moderate to Severe Blepharitis-Associated Keratoconjunctivitis by Fang Ruan, Yunxiao Zang, Ruti Sella, Hongshuang Lu, Shang Li, Ke Yang, Tao Jin, Natalie A. Afshari, Zhiqiang Pan, Ying Jie

“…This open-label nonrandomized clinical trial evaluated 33 patients diagnosed with BKC. …”
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Smartphone video games for cognitive functions and negative symptoms in male with chronic schizophrenia: A randomized controlled trial by Wenhui Wang, Mengting Ye, Yongjie Zhong, Miaomiao Zhang, Yue Wang, Chuanchuan Chen, Yitan Yao, Ziqiao Feng, Xiaoping Yuan, Shenya Shi, Xiaoqin Zhou, Kai Zhang

“…Trial registration: This study was registered in the Chinese Clinical Trial Registry (ChiCTR2100044113) and registered on 11/3/21.…”
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Can “LITE” Procedure Combined With a Short Course Antibiotic Treatment Be Effective in Treating the Chronic PJI?—A Prospective Randomized Controlled Trial by Yang Chen, Haiqi Ding, Qijin Wang, Zida Huang, Chaofan Zhang, Wenbo Li, Yansheng Lin, Yufeng Guo, Xinyu Fang, Wenming Zhang

“…Trial Registration Chinese Clinical Trial Registry: ChiCTR1900027089…”
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Emergence of coinfection with visceral Leishmania infantum in COVID-19 patients: a case‒control field study in an endemic area of visceral leishmaniasis in Iran by Selva Aminizadeh, Behnam Mohammadi-Ghalehbin, Mehdi Mohebali, Homa Hajjaran, Zabih Zarei, Zahra Heidari, Behnaz Akhondi, Zahra Alizadeh, Jafar Aghaei

“…It seems that L. infantum infection can be considered a risk factor for COVID-19, particularly in VL endemic areas. Clinical trial number Not applicable.…”
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Impaired Hepatitis B and COVID-19 vaccination responses show strong concordance in hemodialysis patients with end stage renal disease by Karsten Lürken, Anna Meinecke, Luis A. Manthey, Anne Cossmann, Metodi V. Stankov, Frank Klawonn, Anna Zychlinsky Scharff, Sandra Steffens, Alexandra Dopfer-Jablonka, Frank Müller, Georg M. N. Behrens, Christine Happle

“…Trial registration: German Clinical Trial Registry, DRKS00021152.…”
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Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study by Lucivalda Viegas de Almeida, Aldair Darlan Santos-de-Araújo, Luís Cláudio Nascimento da Silva, Patricia Martins Santos, Mariana Campos Maia, Victória Pereira Frutuoso, Daniel Santos Rocha, Adriana Sousa Rêgo, Daniela Bassi-Dibai

“…Metabolic outcomes are associated and explain between 16.6% and 30.30% of certain variables of resting HRV in post-COVID individuals. Clinical trial number Not applicable.…”
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Two Transcutaneous Stimulation Techniques in Shoulder Pain: Transcutaneous Pulsed Radiofrequency (TPRF) versus Transcutaneous Electrical Nerve Stimulation (TENS): A Comparative Pil... by Mu-Lien Lin, Hung-Wei Chiu, Zao-Ming Shih, Po-Ying Lee, Pei-Zhi Li, Chin-Hong Guo, Yuan-Jie Luo, Shen-Chieh Lin, Kwan-Yu Lin, Yu-Ming Hsu, Angela Pang, Weiwu Pang

“…A prospective, randomized, and double-blind clinical trial. Setting. Academic pain service of a city hospital. …”
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CLINTERVENTIONAL protocol: a randomized controlled trial to evaluate clinical consultations and audiovisual tools for interventional radiology by Pedro Blas García Jurado, Juan José Espejo Herrero, María Sagrario Lombardo Galera, María Eugenia Pérez Montilla, Sara Barranco Acosta, José García-Revillo, Pilar Font Ugalde, Marina Álvarez Benito

“…Key Points We describe the protocol of an interventional radiology randomized clinical trial. The control group will receive procedure information from the referring physician and the experimental group receives additional consultation with interventionalists and views a video. …”
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Traumatic head injuries in children: demographics, injury patterns, and outcomes in Saudi Arabia by Hussin Albargi, Rayan Jafnan Alharbi, Ateeq Almuwallad, Naif Harthi, Yahya Khormi, Hari Krishnan Kanthimathinathan, Sharfuddin Chowdhury

“…These findings highlight the importance of targeting preventive measures for MVCs in older children and improving trauma care for severe cases. Clinical trial number Not applicable.…”
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Preliminary Experiment on the Effect of 18% Substitute Salt on Home Blood Pressure Variability in Hypertensives by Jing Li, Lisha Mu, Huakun Rao, Yangfeng Wu, Hao Wang, Hongbing Tao, Lihong Mu

“…The present study is a phase I clinical trial involving 43 hypertensives in which the effect of 18% sodium substitute salt on the home blood pressure variability (BPV) was observed for 8 weeks with weekly follow-up. …”
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TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled and Parallel‐Group Trial by Xuefei Zhao, Xuedong An, Yashan Cui, Liu Dong, Zhaohui Fang, Zhonghua Zheng, Xinhe Zuo, Huailin Gao, Tianshu Gao, Qing Ni, Fengmei Lian, Xiaolin Tong

“…Methods This multicenter, placebo‐controlled, double‐blind, randomized controlled clinical trial recruited patients from 6 clinical centers in mainland China. …”
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Classification of kinesiophobia in patients after cardiac surgery under extracorporeal circulation in China: latent profile and influencing factors analysis from a cross-sectional... by Qi Li, Rong Wang, Yanmei Gu, Tong Ren, Jing Jing Piao, Wenhui Xing, Yujing Liang

“…These findings provide a basis for implementing preventive interventions in cardiac rehabilitation.Trial registration number The research is registered with the Chinese Clinical Trial Registry (ChiCTR2200057895).…”
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