Examining the impact of social stressor stimuli in eliciting physiological reactivity in children and adolescents with autism spectrum disorder: a systematic review and meta-analys... by Samantha Burns, Agnes S K Wong, Earl Woodruff

“…The second source of literature will be across grey literature, including ProQuest Dissertations & Theses Global and across clinical trial registries in August 2021. Hand searching of references will be performed on the reference lists of all included studies. …”
Get full text

The Impact of the COVID-19 Pandemic on the Mental Health of Older Primary Care Patients and Their Family Members by Tara Seibert, Matthew W. Schroeder, Anthony J. Perkins, Seho Park, Eleanor Batista-Malat, Katharine J. Head, Tamilyn Bakas, Malaz Boustani, Nicole R. Fowler

“…This study compared the rates of depression and anxiety in a sample of older primary care patients (aged ≥65 years old) and their family members recruited for a clinical trial before and during the COVID-19 pandemic. …”
Get full text

Digital measurement of ocular microtremor in Parkinson's disease: Protocol for a pilot study to assess reliability and clinical validation. by Lisa Graham, Rodrigo Vitorio, Richard Walker, Alan Godfrey, Rosie Morris, Samuel Stuart

“…Identifying OMT as a PD biomarker could better support clinical assessment, enabling improved provision of care to patients with advanced disease monitoring. Clinical trial registration: This trial is registered at clinicaltrials.gov (NCT06051877; September 2023).…”
Get full text

Association Between Weight Loss and Changes in Optimal Positive Airway Pressure Levels in Patients With Obstructive Sleep Apnea by Ji Ho Choi, Dong Yun Lee, Tae Kyoung Ha, Ji Eun Moon

Get full text

Efficacy of Exenatide Administered Twice Daily in Body Mass Index Reduction in Patients with Type 2 Diabetes Mellitus by Jie Zhang, Tong-Zhang Xian, Yu Teng, Xiuzhi Wang, Ming-Xiao Wu, Chen Li, Weihao Wang, Fuli Man, Xianbo Zhang, Xiaoxia Wang, Li-Xin Guo

“…Trial Registration. Chinese Clinical Trial Registry (ChiCTR-1800015658).…”
Get full text

Treatment of Multiple Sclerosis with Cladribine Tablets: Literature Review and the Guidance of the Lithuanian Association of Neurologists by R. Kizlaitienė, D. Mickevičienė, L. Malcienė, N. Giedraitienė, R. Balnytė, D. Jatužis

“…During more than five years after the approval of the medicinal product, the new clinical trial data and the Real-World Evidence (RWE) on the efficacy and safety of cladribine tablets have become available, based on which, several national and international expert panels, as well as the Lithuanian Association of Neurologists, have issued guidance on the use of cladribine tablets reviewed in this article. …”
Get full text

The heart rate on admission was associated with the mortality in elderly patients with hip fractures: a retrospective cohort study from a trauma centre in northwestern China by Zhi Yang, Wei-Song Zhang, Shao-Hua Chen, Bin-Fei Zhang

“…When the heart rate was over 84 beats per minute, the risk of death peaked, and there was no association with heart rate anymore.Trial registration number This study was registered on the website of the Chinese Clinical Trial Registry (ChiCTR: ChiCTR2200057323).…”
Get full text

Exploring the Effects of Sub-Dissociative Doses of Ketamine on Sedation Quality in Bronchoscopy: A Double-Blind Clinical Study by Hamidreza Shetabi, Samira Rostami

“…Methods: This research utilized randomized clinical trial design involving three cohorts, each consisting of 30 participants. …”
Get full text

Effects of COVID-19 on short-term outcomes of hip arthroplasty: a multicenter, retrospective, propensity score matched study by Shih-Hui Peng, Yu-Chih Lin, Chih-Hsiang Chang, Chih-Chien Hu, Lan-Yan Yang, Yuhan Chang

Get full text

Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial by Asif Hussain, Sushil Kumar Saini, Jaydeep Patel, Chandra Prakash Pal, Hemant Singh Chahar, Rohit Yadav

“…Methods: This is a blinded randomized clinical trial conducted at a government hospital. Patients aged 50–89 years with bone mineral density (BMD) T score < −2.5 or < −1.5 with 2 mild vertebral fractures or 1 moderate vertebral fractures were randomized to receive placebo versus zoledronic acid. …”
Get full text

Effects of a Groin Pain Prevention Program in Male High School Soccer Players: A Cluster-Randomized Controlled Trial by Kazuki Fujisaki, Kiyokazu Akasaka, Takahiro Otsudo, Hiroshi Hattori, Yuki Hasebe, Toby Hall

“… # Design Randomized Controlled Clinical Trial. # Methods A cluster randomized controlled trial spanning 16 weeks was conducted on 202 high school soccer players from seven high schools in a Japanese under 18 Soccer League. …”
Get full text

Reducing children’s anxiety and pain in dental environment using an eye massage device combined with natural sounds—a randomized controlled trial by Dajma Abed, Jamila Bchara, Dani Abed, Jina Alfeel, Nada Bshara

“…A total of 105 children aged between 8 and 10 years whose dental treatment required inferior alveolar nerve block (IANB) injection participated in this randomized controlled clinical trial. The participants were randomly divided into three groups: Group A: eye massage with natural sounds; Group B: eye massage only; and Group C (control group): traditional behavior management techniques. …”
Get full text

Diagnosis of Intraductal Biliary Lesions: Towards Greater Accuracy and Safety by Sung Woo Ko, Seung Bae Yoon

“…Methods: This single-center, randomized, parallel-group clinical trial included patients aged 20 to 85 years admitted to Kyoto University Hospital for biliary strictures. …”
Get full text

Atropine 0.01% for the Control of Myopia in Chinese Children: Effect on Accommodation Functions and Pupil Size by Yuliang Wang, Jing Yao, Xiaomei Qu

“…This was a single-center randomized clinical trial. 63 participants with myopia of at least −0.50 D and astigmatism of ≤−2.50 D were enrolled and randomized to receive atropine 0.01% once nightly with regular single-vision lenses or to wear regular single-vision lenses, in an allocation ratio of 3 : 2. …”
Get full text

Feasibility and staff acceptability of implementing Xpert HIV-1 viral load point-of-care testing: a pilot study in San Francisco by Kelvin Moore Jr., Noelle Le Tourneau, Jasmin Alvarez, Santos Rodriguez, Janessa Broussard, Pierre-Cédric Crouch, Jorge Roman, Patricia Defechereux, Jason Bena, Kimberly A. Koester, Lissa Moran, Christopher Pilcher, Robert Grant, Katerina A. Christopoulos

“…While the Xpert demonstrated comparable results to standard-of-care testing and staff found it acceptable, further work is needed to develop the workflow and implementation strategies that would enable real-time use and improved patient care. Clinical trial Not applicable.…”
Get full text

A serosurvey study of hand, foot and mouth disease in healthy children aged 6 to 71 months old in West Bandung and Bandung Region, Indonesia by Rodman Tarigan Girsang, Kusnandi Rusmil, Eddy Fadlyana, Budi Setiabudiawan, Riyadi Adrizain, Rizky Perdana Mulyadi, Arief Budiman, Rona Kania Utami, Behesti Zahra Mardiah, Muhammad Gilang Dwi Putra, Frizka Primadewi Fulendry, Dinda Tiaraningrum Nashsyah, Hadyana Sukandar

“…Trial registration This study is registered at clinicaltrials.gov, National Clinical Trial (NCT) No. NCT05637229.…”
Get full text

Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration by Hamid Riazi-Esfahani, Hooshang Faghihi, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hassan Khojasteh, Ahmed Husein Ahmed, Shahin Faghihi, Ali Fakhraie, Mohammad Hossein Zamani, Samin Ghasemi, Esmaeil Asadi Khameneh, Elias Khalili Pour

“…Conclusion Baseline OCT biomarkers, including SIPED, IRF, and PED width, may predict visual acuity changes in nAMD patients treated with aflibercept, highlighting the need for individualized monitoring. Clinical trial number Not applicable.…”
Get full text

Cognitive Deficit-Related Interhemispheric Asynchrony within the Medial Hub of the Default Mode Network Aids in Classifying the Hyperthyroid Patients by Mengmeng Zhi, Zhenghua Hou, Yuqun Zhang, Yingying Yue, Ling Li, Yonggui Yuan

“…The altered interhemispheric coordination in the hub of the default mode network may implicated in the modulation of episodic memory in HPs patients and the distinct feature of the interhemispheric asynchrony may be treated as a potential target for the early recognition and intervention for the HPs with cognitive impairments. Clinical Trial Registration. This is a study of the neurological basis for dysfunction of mood and cognition in hyperthyroid patients: a resting-state fMRI study (registration number: ChiCTR-OOC-16008607).…”
Get full text

Lactate/albumin ratio as a prognostic biomarker for in-hospital mortality in pediatric patients with necrotizing enterocolitis by Ban Li, Yuanzhi Chen, Zhen Yang, Xianglun Sun, Cheng Tian, Jingsi Liu, Lihua Yuan, Kanglin Dai

“…However, given the limitations of our research, more prospective studies are still needed in the future to test the predictive value of L/A ratio for the prognosis of NEC disease. Clinical trial number Not applicable.…”
Get full text

Effect of intraoperative noise isolation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: protocol for a randomized controlled trial by Chong Fu, Fan Xia, Zihan Yan, Han-bing Xu, Wei-ming Zhao, Yi-shan Lei, Chang Xu, Wen-wen Huo, Duo-duo Tao, Juan Wang, Xi-sheng Shan, Ke Peng, Hong Liu, Fu-hai Ji, Hua-yue Liu

“…Trial registration Chinese Clinical Trial Registry (ChiCTR2400087460).…”
Get full text