Clinical significance of retrograde inferior parathyroid protection technique based on thymus preservation in thyroid surgery by Shouyi Yan, Yuhan Chen, Wenxin Zhao, Liyong Zhang, Shaojun Cai

“…Conclusion Retrograde inferior parathyroid protection technique (RIPPT) underscores the importance of protecting inferior parathyroid gland (IPG) in thyroid surgery and has been demonstrated to be effective in the rapid identification and functional preservation of IPG, based on short-term outcomes. Clinical trial number Not applicable.…”
Get full text

Clinical Effect of Teucrium polium Extract Ointment on Post Pilonidal Sinus Excision Wound Healing: A Randomized Controlled Trial by Reza Hosseinpour, Nuruddin Hosseini, Seyedeh Fatemeh Hekmatzadeh, Saadat Mehrabi, Hossein Sadeghi Mansourkhani, Marita Mohamadshahi

“…Methods: This randomized double-blind clinical trial was conducted from April 2021 to March 2022. …”
Get full text

The engagement of healthcare providers in implementing the selfBACK randomised controlled trial – A mixed-methods process evaluation by Mette Jensen Stochkendahl, Barbara I Nicholl, Karen Wood, Frances S Mair, Paul Jarle Mork, Karen Søgaard, Charlotte DN Rasmussen

“…Aims We aimed to examine HCPs’ engagement in patient recruitment for the selfBACK app clinical trial and explore their perceptions of the app. …”
Get full text

Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…Future studies should determine if LF-rTMS alone or in conjunction with practice/training would be more effective. Clinical Trial Registration Information. This trial is registered with unique identifier CRD42016042181.…”
Get full text

Effectiveness of an environmental educational program on intern dentists’ knowledge and practices regarding eco-friendly green dentistry: a quasi-experimental study by Eman Helmy Hassan, Nesma Lotfy, Mamdouh Hanafy Abdou, Ebtisam Mohamed Fetohy, Mohamed Fakhry Hussein

“…The successful educational program in early career is important in reducing waste generation and resource consumption, as well as potential cost savings on the long run. Clinical trial registration number PACTR202405544685014. …”
Get full text

A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…Our objective was to provide an overview of the clinical trial evidence on the effect of n-of-1 trials on clinical outcomes.…”
Get full text

Cost-effectiveness of Ruxolitinib vs Best Available Therapy in the Treatment of Myelofibrosis in Spain by María Teresa Gómez-Casares, Juan Carlos Hernández-Boluda, Antonio Jiménez-Velasco, Joaquin Martínez-López, María Giovanna Ferrario, Irmina Gozalbo, Joana Gostkorzewicz, Rudi Subirá

“…The population was assumed to be similar to that of the COMFORT-II clinical trial (CT), which was also the source of treatment efficacy data. …”
Get full text

The influence of cognitive flexibility on research abilities among medical students: cross-section study by Sarah S. Almutawa, Norah A. Alshehri, Abdulrahman A. AlNoshan, Nasser M. AbuDujain, Khaled S. Almutawa, Ahmed S. Almutawa

“…Meanwhile, research efforts should aim to test more specific and accountable methods for enhancing cognitive flexibility, as well as their impact on learning and clinical practice. Clinical trial number Not applicable.…”
Get full text

Development and pilot testing of a nurse-led common-sense model of self-regulation-based heart failure self-care program by Zehao Huang, Sek Ying Chair

“…Trial registration Chinese Clinical Trial Registry (No., ChiCTR2300068156; February 9, 2023).…”
Get full text

In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. by Baback Roshanravan, Sophia Z Liu, Amir S Ali, Eric G Shankland, Chessa Goss, John K Amory, H Thomas Robertson, David J Marcinek, Kevin E Conley

“…Here, we describe the impact of a first-in-class cardiolipin-binding compound that is targeted to mitochondria and improves oxidative phosphorylation capacity (Elamipretide, ELAM) in a randomized, double-blind, placebo-controlled clinical trial.<h4>Methods</h4>Non-invasive magnetic resonance and optical spectroscopy provided measures of mitochondrial capacity (ATPmax) with exercise and mitochondrial coupling (ATP supply per O2 uptake; P/O) at rest. …”
Get full text

The effect of telenursing follow-up on blood glycosylated hemoglobin and quality of life in the elderly with diabetes type 2 by Elahe Asadi, Fariba Borhani, Abbas Abbaszadeh

“…Materials and Methods: In this clinical trial study, 90 patients with type 2 diabetes referred to the hospitals affiliated with Shahid Beheshti University of Medical Sciences in 1401–1402 were divided into two control and experimental groups (45 patients in each group) by the simple random sampling method. …”
Get full text

Comparison of a ready-to-use intranasal dexmedetomidine spray with traditional intranasal dexmedetomidine drops for sedation in preschool children: a prospective, randomized, contr... by Qi-Qi Jin, Wei-Cha Cai, Ying-Feng Zhou, Yan-Tong Zhang, Gang Chen, Meng-Ting Xu, Jun Li, Kai-Ming Yuan

“…Compliance with induction was comparable, with 53.5% in the DS group and 40.0% in the DD group demonstrating “optimal” compliance.ConclusionBoth intranasal spray and syringe drop methods were highly effective in providing sedation and anxiolysis, but the ready-to-use intranasal dexmedetomidine spray was more acceptable to children, offering a viable alternative to the syringe method.Clinical Trial RegistrationChiCTR.org.cn, identifier ChiCTR2400089374.…”
Get full text

Quantitation of Phenolic Compounds Related to Antioxidant and Antiosteoporosis Activities in Ripe and Unripe Maesil (Prunus mume) by Chong Woon Cho, Young Sik Park, Xi-Tao Yan, Hyun June Kim, Young Ho Kim, Kyung Tae Kim, Chu Van Men, Jong Seong Kang

Get full text

The effects of integrated traditional Chinese and western medicine rehabilitation programs on post-acute ankle sprain: A randomized controlled trial study protocol. by Hang Gao, Xiao Chen, Jiayi Ren, Xinglai Zhang, Yuqian Hu, Zhao Ma, Yuanjia Gu, Jiming Tao, Weian Yuan

“…<h4>Trial registration</h4>The trial was registered at Chinese Clinical Trial Registry https://www.chictr.org.cn/showproj.html?…”
Get full text

Evaluation of ior ® Leukocim efficacy on patients with Neutropenia. by Ana María Ramos Cedeño, Leslie Pérez Ruiz, Julio Dámaso Fernández Águila, Tamara Guerra, Maritza Cabrera Zamora, Hailen Bobillo López

“…</p><p><strong>Abstract</strong></p><p>To demonstrate the effectiveness of Leukocim an open, phase IV clinical trial was designed, 39 patients from Cienfuegos were evaluated with 73 neutropenic episodes in primary or secondary prophylaxis or treatment, the demographic parameters behaved with an age 49.86 year old average, the predominant sex was the feminine 64.38%, 73.97% belonged to the white race, when the effectiveness was analyzed we obtained that 46.5% received the treatment in an ambulatory way, whereas 52.1% was hospitalized; one patient abandoned before beginning the treatment, the 12,3% of patients abandoned the study, the dose number received in order to correction CAN was between 3 and 7, behaving with a stocking of 1.26 before receiving the treatment and of 5.82 after the same one receiving the next cycle chemo y/o radiotherapy in time demonstrating this way the effectiveness of the product.…”
Get full text

Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges by Man Wang, Fei Yu, Yuan Zhang

“…Owing to gaps between preclinical and clinical studies, nano-immunotherapy faces multiple challenges, including the biosafety of nanomaterials and clinical trial design. In this review, we provide an overview of cancer immunotherapy and summarize the evidence indicating how nanomedicine-based approaches increase the efficacy of immunotherapies. …”
Get full text

Effects on Parental Stress of Early Home-Based CareToy Intervention in Low-Risk Preterm Infants by Giuseppina Sgandurra, Elena Beani, Emanuela Inguaggiato, Jakob Lorentzen, Jens Bo Nielsen, Giovanni Cioni

“…This trial is registered with Clinical Trial.gov NCT01990183.…”
Get full text

Comparison of the Efficacy and Safety of Temporary Spinal Cord Stimulation versus Pulsed Radiofrequency for Postherpetic Neuralgia: A Prospective Randomized Controlled Trial by Xiaohong Li, Pan Chen, Jian He, Xiang Huang, Dacheng Tang, Lumiao Chen, Xiaoping Wang

“…This study was prospectively registered in the Chinese Clinical Trial Registry (ChiCTR2100050647).…”
Get full text

Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway by Heung-Man Lee, Ju-Hyung Kang, Jae-Min Shin, Seoung-Ae Lee, Il-Ho Park

Get full text

Influence of psychological resilience on compassion fatigue in nurses in the operating room: a cross-sectional study in China by Cong Fu, Ying Wang, Xiaopan Shi, Yang Wang, Weihua Liu, Gaijing Wang

“…Appropriate interventions are recommended to address these factors and reduce nurses’ compassion fatigue. Clinical trial number Not applicable.…”
Get full text