Sustained response off treatment after fostamatinib in refractory immune thrombocytopenia: A series of four case reports by Waleed Ghanima, Francisco Javier Lucas Boronat, Valentina Carrai, Stefan Rackwitz

“…He was pre-treated with prednisone and rituximab before being in the FIT-2 clinical trial (placebo). He received fostamatinib in the FIT-3 open-label extension for seven weeks and maintained SROT for 2.5 years. …”
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Comparative Analysis of the Influence of Selected Physical Factors on the Level of Pain in the Course of Temporomandibular Joint Disorders by Łukasz Kopacz, Żaneta Ciosek, Helena Gronwald, Piotr Skomro, Roman Ardan, Danuta Lietz-Kijak

“…The study included 60 patients of both genders with diagnosed TMD in a clinical trial. The participants were randomly divided into two groups. …”
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The Effects of Foot Reflexology Massage on the Sleep Quality of Nurses Working in the Selected Hospitals of Sabzevar University of Medical Sciences by Mojgan Gholitabar Omrani, mohammad Reza Ghasemi, Mohammad Gholizadeh Gerdrodbari, Roghayeh Javan, Neda Mahdavifar

“…Therefore, this study aimed to evaluate the effects of foot reflexology massage on the sleep quality of nurses. This controlled clinical trial was conducted on 80 nurses working in the selected hospitals of Sabzevar University of Medical Sciences. …”
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Retrospective MRI analysis of 418 adult shoulder joints to assess the physiological morphology of the glenoid in a low-grade osteoarthritic population by Marc-Pascal Meier, Lars Erik Brandt, Mark-Tilmann Seitz, Paul Jonathan Roch, Katharina Jäckle, Ali Seif Amir Hosseini, Wolfgang Lehmann, Thelonius Hawellek

“…These findings have to be considered in shoulder diagnostics and surgery. Clinical trial number Not applicable.…”
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Prospective Randomized Controlled Study of Hemostatic Efficacy with Kaolin-Impregnated Dressings in Diabetic Foot Ulcers Taking Anticoagulants Undergoing Debridement in an Outpatie... by Yeok Gu Hwang, Jin Woo Lee, Eun Ae Won, Seung Hwan Han

“…A prospective, randomized, clinical trial study was performed in twenty-six patients with diabetic foot ulcers who take an anticoagulant requiring minor debridement in an outpatient clinic. …”
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Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus by Shreya Mukhopadhyay, Ioannis Manolaridis, Christopher Warren, Aimin Tang, Gregory O’Donnell, Bin Luo, Ryan P. Staupe, Kalpit A. Vora, Zhifeng Chen

“…It is the precursor for MK1654 (clesrovimab), which successfully completed a Phase III clinical trial. <b>Methods:</b> In this study, we isolated two anti-IDs, 1A6 and 1D4, targeting RB1 CDR regions, demonstrating that 1A6 competes fully with RSV F in binding to RB1. …”
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Efficacy and safety of LiWei capsule in chronic non-atrophic gastritis with erosions: a randomized controlled trial by Danyang Cui, Xiao Geng, Juan Wang, Xu Han, Zhijun Huang, Miao Jiang, Yang Gong

“…Trial registration: ChiCTR2100052010, assigned by the Chinese Clinical Trial Registry, registration date 13/10/2021.…”
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Therapeutic applications of artemisinin in ophthalmic diseases by Hao Sun, Ping Zhao, Lianghui Zhao, Zhizhong Zhao, Haoyu Chen, Cong Ren, Bin Guo

“…However, since ocular diseases are often caused by various factors, how artemisinin can play a good disease prevention role by modulating these factors needs to be further verified, and most of the current studies focus on in vitro and animal experiments, lacking sufficient information on clinical trial studies. To better explore and perfect the mechanism of action of artemisinin in ophthalmic diseases, and to better promote the clinical application of artemisinin, this study reviews the latest progress of artemisinin treatment for uveitis, uveal melanoma, age-related macular degeneration, diabetic retinopathy, ocular neovascularization, and dry eye, and it will provide theoretical support for the large-scale application of artemisinin in ophthalmic diseases in the future.…”
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“The effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty”. A prospective, randomized, double-blind controlled... by Tamer Samir Abdelsalam Abdelaziz, Hatem Elsayed Mohammed Elsayed, Doaa Mohammed Kamal Eldin, Ismail Mohammed Ibrahim

“…Conclusions IM dexmedetomidine premedication was more efficient than gabapentin in the reduction of the emergence agitation incidence, severity, and postoperative pain scores after rhinoplasty in adults. Clinical trial registration number ID NCT05626998 on 25/11/2022.…”
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A Systematic Review on Safety and Efficacy of Ayurvedic Interventions in Hemiplegia () by Akashlal M. MD (Ay), Pratibha P Nair MD (Ay), Devi R Nair MD (Ay), Azeem Ahmad MD (Ay), B Chandrasekhararao MD (Ay), D Sudhakar MD (Ay), Srikanth Narayanam PhD (Ay), Rabinarayan Acharya PhD (Ay)

“…The study involved a search across multiple online databases and online clinical trial registries. Additionally, major Ayurveda postgraduate institutes were contacted to acquire unpublished trial data related to hemiplegia/Pakshaghata. …”
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The effect of dienogest and gonadotropin-releasing hormone agonist on pelvic pain after laparoscopic surgery for endometriosis: An RCT by Fatemeh Davari Tanha, Azam Rasti, Hamideh Pakniat, Shohreh Salimi Setudeh

“…Materials and Methods: In this randomized clinical trial study, 104 women with endometriosis who were referred to the Department of Reproductive Medicine of Yas hospital, Tehran, Iran, between April 2022 and March 2023 were studied. …”
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Clinical Comparison between HD-tDCS and tDCS for Improving Upper Limb Motor Function: A Randomized, Double-Blinded, Sham-Controlled Trial by Yaqin Zeng, Ruidong Cheng, Li Zhang, Shan Fang, Shaomin Zhang, Minmin Wang, Qian Lv, Yunlan Dai, Xinyi Gong, Feng Liang

“…This randomized, sham-controlled clinical trial included 69 patients with subcortical stroke. …”
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Mixed vulnerabilities: the biological risk of high parity is aggravated by emergency referral in Benin, Malawi, Tanzania and Uganda by Manuela Straneo, Lenka Beňová, Thomas van den Akker, Muzdalifat S. Abeid, Elizabeth Ayebare, Jean-Paul Dossou, Greta Handing, Bianca Kandeya, Andrea B. Pembe, Claudia Hanson

“…Trial registration Pan African Clinical Trial Registry ( www.pactr.org ): PACTR202006793783148. …”
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The Effects of Extra Virgin Olive Oil on Alanine Aminotransferase, Aspartate Aminotransferase, and Ultrasonographic Indices of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease... by Farzad Shidfar, Samaneh Sadat Bahrololumi, Saeid Doaei, Assieh Mohammadzadeh, Maryam Gholamalizadeh, Ali Mohammadimanesh

“…This study aimed to examine the effect of virgin olive oil on alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and the severity of steatosis in the NAFLD patients undergoing a weight-loss diet. Methods. This clinical trial was carried out on 50 patients with nonalcoholic fatty liver (mean age of 45.91 ± 9.61 years, mean BMI of 29.7 ± 0.58 Kg/m2) and the subjects were randomly assigned to the olive oil group (receiving the equivalent of 20% of their total daily energy requirement from olive oil) or the control group (with normal consumption of oil) for 12 weeks. …”
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Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation by Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Toshio Horiuchi, Takahiko Omameuda, Kiichiro Takadra, Ryosuke Akimoto, Yasuharu Onishi, Yasunaru Sakuma, Koichi Mizuta

“…Conclusions This study demonstrates that IMDs are a potent independent risk factor for CMV infection following pediatric liver transplantation. Clinical trial number Not applicable.…”
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Mixed-methods process evaluation of a proactive approach to healthcare in Parkinson’s disease—ParkProReakt: a protocol of a hybrid efficacy-implementation study by Xinyu Huang, Max Geraedts, Elke Kalbe, Carsten Eggers, David José Pedrosa, Ann-Kristin Folkerts, Marcin Grzegorzek, Marlena van Munster, Johanne Stümpel, Natalie Altschuck, Ingmar Wellach, Hannes Boebinger, Anna Pedrosa, Kati Niemand, Dirk Becker, Nicole Pohlschmidt, Isabel Doblinger, Kristina Schmidt, Daniel Wolferts, Marius Nisslmueller, Gennet Beer, Mohammad Osman Ashraf, Florian Eberhardt, Rebecca Wichartz, Birgit Samans, Volker Gross, Keywan Sohrabi, Linda Kerkemeyer, Uemran Seven, Paulina Olgemoeller, Artur Piet, Mona Irsfeld, Marlena van Munster

“…This study protocol describes the process evaluation within a randomised clinical trial to assess the implementation and its impact on patient health outcomes of ParkProReakt—a proactive, multidisciplinary, digitally supported care model for community-dwelling PwPD.Methods and analysis The hybrid efficacy-implementation study will assess key implementation outcomes using the Medical Research Council framework for complex interventions alongside a randomised controlled trial. …”
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Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial by Annie Altman-Merino, MD, Kemberlee Bonnet, MA, David Schlundt, PhD, Jesse Wrenn, MD, PhD, Wesley H. Self, MD, MPH, Elisa J. Gordon, PhD, MPH, Alexander T. Hawkins, MD, MPH

“…In a survey of 218 subjects, 62% of respondents reported willingness to participate in a randomized clinical trial. “What my doctor thinks,” followed by “What I have experienced in the past” were the most important decision-making factors. …”
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Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial by Yaadwinder Shergill, Danielle B. Rice, Eve-Ling Khoo, Virginia Jarvis, Tinghua Zhang, Monica Taljaard, Keith G. Wilson, Heather Romanow, Brittany Glynn, Rebecca Small, Joshua A. Rash, Andra Smith, Lynette Monteiro, Catherine Smyth, Patricia A. Poulin

“…Conclusion. Our randomized clinical trial did not find significant benefits of group-based mindfulness-based stress reduction for the management of CNP. …”
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Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants by Guiqiang Wang, Kexin Zhao, Xiuli Zhao, Yimin Cui, Peng He, Tianzuo Zhang, Yanchao Wang, Rui Shi, Yanhua Li, Qian Wang, Yanping Ren, Zhisong Chen, Xuedan Zhao, Zekang Xie, Yufei Liang, Qingyun Tian, Jing Pan, Chao Zhang, Ying Han, Yuyang Dai, Siyang Ni, Yun Zhang, Xinjie Yang, Yongpan Fu, Dongfang Liu, Jing Li, Miaomiao Zhang, Zhongyu Hu, Liangzhi Xie

“…Reactogenicity was generally mild, with one adverse event of special interest (AESI) and 9 ≥Grade 3 treatment-related adverse events (TRAEs); all recovered within 3 days.Conclusions SCTV01C, when administered as both a primary series and a booster vaccination, exhibited encouraging sustained immunogenicity against both antigen-matched and antigen-mismatched variants, with no significant safety concerns.Clinical trial registration www.clinicaltrials.gov identifier is NCT05148091.…”
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Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial by Mohammad Jafar Eghbal, Ali Haeri, Arash Shahravan, Ali Kazemi, Fariborz Moazami, Mohammad Ali Mozayeni, Eshaghali Saberi, Mohammad Samiei, Mehdi Vatanpour, Alireza Akbarzade Baghban, Mahta Fazlyab, Ardavan Parhizkar, Mahboobe Ahmadi, Nazila Akbarian Rad, Shima Bijari, Delaram Bineshmarvasti, Paria Davoudi, Roya Dehghan, Mandana Dehghani, Habibollah Ebrahimi, Nafiseh Emami, Nafiseh Farajian, Rahim Fereidooni, Gelareh Ghobadi, Mostafa Ghodrati, Atefeh Gohari, Azadeh Hashemi, Mohammadreza Hosseini, Elham Karami, Nasir Kheirabadi, Sepideh Kozegari, Hadi Labaf Ghasemi, Alireza Majidi, Parastu Malekzadeh, Vahid Mehrabi, Mehrnush Mohammadi, Leila Moradi Eslami, Atefeh Noghani, Negin Omatali, Negar Pourhatami, Behnam Rahbani Nobar, Saeid Rahmani, Parviz Shafaq, Sara Soofiabadi, Somaye Teimoori, Farzaneh Vatandoost, Saeed Asgary

“…This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. …”
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