A phase I study of the CDK4/6 inhibitor ribociclib combined with gemcitabine in patients with advanced solid tumors by Aurora Norman, Mahesh Seetharam, Jacob Allred, Jianping Kong, Mateusz Opyrchal, Wen Wee Ma, Yanyan Lou, Grace K. Dy, Amit Mahipal, S. John Weroha, Andrea E. Wahner Hendrickson, Joel M. Reid, Alex A. Adjei

“…Biomarkers such as Rb status and activity of CDK2 and CDK4/6 complexes may help to select patients who may respond better to the combination of gemcitabine and ribociclib. Clinical Trial Registration NCT03237390.…”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Gang, Roggers, Okello, Denis, Yeongjun, Ban, Kang, Youngmin

“…Additionally, toxicity and clinical trial data for A. africana are limited with most toxicological assessments being acute in nature. …”
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Effect of core stability exercises on upper limb reaching in children with spastic hemiparetic cerebral palsy: a randomized controlled trial by Nadia Hassan Abd-Elhameed, Heballah Mohammed Kamal, Mai Elsayed Abbass

“…Trial registration This study was authorized by the Faculty of Physical Therapy’s ethics committee under the number “REC/012/003125” and registered in ClinicalTrial.gov with the number “NCT05316090” on 9 April 2022 retrospectively.…”
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Scoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children. by Courtney C Choy, Kate Nyhan, Kima Savusa, Christina Soti-Ulberg, Rochelle K Rosen, Take Naseri, Nicola L Hawley, Mona Sharifi

“…To investigate existing interventions for adaptation and potential use in Pacific Islander communities, we will search Scopus, MEDLINE ALL (Ovid), EMBASE (Ovid), Yale-licensed Web of Science Core Collection, Cochrane Library, CINAHL (EBSCOhost), ProQuest Dissertations & Theses Global, Global Health (EBSCO), non-indexed Pacific journals, grey literature, government reports, and clinical trial registrations. The Joanna Briggs Institute Manual for Evidence Synthesis and the Preferred Reporting Items for Scoping Reviews will guide data extraction, evidence mapping, synthesis, and reporting of information including study population, intervention components, behavioral changes, health and implementation outcomes, theoretical frameworks, and evaluation measures.…”
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Within-session propulsion asymmetry changes have a limited effect on gait asymmetry post-stroke by Sarah A. Kettlety, James M. Finley, Kristan A. Leech

“…Reducing propulsive asymmetry using biofeedback is unlikely to produce substantial reductions in overall gait asymmetry, suggesting that biofeedback-based approaches to reduce propulsion asymmetry may need to be combined with other interventions to improve overall gait asymmetry. Clinical Trial Registration. NCT04411303.…”
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Effects of Advanced Platelet Rich Fibrin (A-PRF+), Enamel Matrix Derivative (EMD) and Open Flap Debridement on clinical and wound healing parameters in molar furcation sites: A cas... by L. Pitzurra, D. Vasdravellis, N.A.M. Rosema, S. Bizzarro, B.G. Loos

“…The defects in the A-PRF+ group showed delayed early healing compared to the EMD and OFD groups.ConclusionThe case series (RCT design) suggests a slight advantage for A-PRF+ over EMD and OFD, regarding the regressing of a furcation II to grade I; however this treatment showed delayed early wound healing compared to EMD or OFD.Clinical Trial Registrationhttps://www.isrctn.com/, identifier ISRCTN13520922.…”
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Phakic Posterior Chamber Intraocular Lens with a Central Hole in Treating Patients with Moderate to High Myopia: A Meta-Analysis by Ying Tang, Jian Ye

“…PubMed, Embase, Cochrane Library, Clinical Trial, China Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), and China Science Periodical Database (CSPD) were searched online. …”
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Investigating the Effects of Performing the Early Mobilization Protocol on Postoperative Hemorrhaging in Cardiac Surgery Patients by Hanie Dahmardeh

“…Methods: This research is a clinical trial study conducted in 2023-2024 at Ali Ibn AbiTalib Hospital in Zahedan, Iran, on 100 patients undergoing cardiac surgery. …”
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Effect of 4DryField® PH, a Novel Adhesion Barrier, on Recurrence of Intestinal Adhesions after Extensive Visceral Adhesiolysis by Gerhard Blumhardt, Matthias Haas, Stefanie Polte

“…In this retrospective one-center clinical trial, the course of patients with extensive abdominal adhesiolysis and application of a recent starch-based formulation, 4DryField PH (4DF), is analyzed. …”
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The Effect of the Idiopathic Epiretinal Membrane and Surgically Induced Posterior Vitreous Detachment on the Retinal Nerve Fiber Layer by A. Altun

“…Patients with unilateral ERM with vitreomacular traction were included in this prospective, randomized, and controlled clinical trial. The control group (Group 1) was formed with the nonoperated fellow eyes of the patients, and the study group (Group 2) was formed with the eyes that underwent PPV including idiopathic ERM and ILM peeling. …”
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Effectiveness of Spinal Stabilization Exercises on Dynamic Balance in Adults with Chronic Low Back Pain by Yousef M. Alshehre, Khalid Alkhathami, Kelli Brizzolara, Mark Weber, Sharon Wang-Price

“… # Study Design A double-blind randomized clinical trial. # Methods Forty participants with CLBP were assigned randomly into either an SSE group or a general exercise (GE) group, which consisted of flexibility and range-of-motion exercises. …”
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Spanish version of the short European Health Literacy Survey Questionnaire HLS-Q12: Transcultural adaptation and psychometric properties. by Sergio Muñoz-Villaverde, Leticia Serrano-Oviedo, María Martínez-García, Yolanda Pardo, Llüisa Tares-Montserrat, Francisco Javier Gómez-Romero, Paloma Garcimartin

“…The sample consisted of 60 patients who initiated cancer treatment for the first time within a clinical trial. Double direct translation, back-translation, cognitive debriefing with a 10-patient sample, and an expert committee were used for cross-cultural adaptation. …”
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Hemostatic effect of oxidized regenerated cellulose vs. topical tranexamic acid in total knee arthroplasty—a prospective randomized controlled trial by Bowei Li, Wenjie Pan, Jianbing Ma, Yuanchi Huang

“…This provides a safe and effective hemostatic option for patients with severe underlying diseases or contraindications to tranexamic acid.Clinical Trial registrationhttps://www.chictr.org.cn/bin/project/edit?…”
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Case Report: Two years of compassionate use with Olipudase-alfa in a child with neurovisceral acid sphingomyelinase deficiency by Federica Deodato, Sara Boenzi, Benedetta Greco, Alessia Graziosi, Carlo Dionisi-Vici

“…Recently, Olipudase-alfa, an intravenous enzyme replacement therapy, has been approved for non-neurological manifestations based on clinical trial results showing significant improvements. …”
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Frailty risk prediction models for patients undergoing maintenance hemodialysis in China: a systematic review by Yu Zhong, Songmei Cao, Liangying Chen, Teng Li, Wei Ye

“…To develop more accurate and practical prediction models, future studies must rely on large-sample, multicenter prospective cohort studies and adhere to a rigorous study design. Clinical trial number Not applicable.…”
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The Effect of Phase I Cardiac Rehabilitation on the Rate of Delirium After Coronary Artery Bypass Graft Surgery by Kolsoum Parnan Emamverdi, Zahra Sadat Manzari, Seyed Reza Mazloum

“…Materials and Methods: This clinical trial study was performed on 60 patients in the cardiac intensive care unit of Imam Reza Hospital in Mashhad during 1398. …”
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Cost-Effectiveness of Hypochlorous Acid Preserved Wound Cleanser versus Saline Irrigation in Conjunction with Ultrasonic Debridement for Complex Wounds by Peter J. Mallow, John M. Hiebert, Martin C. Robson

“…All clinical data were obtained from a prospective clinical trial. Cost data were obtained from the publicly available data sources in 2021 US dollars. …”
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The Effect of Omeprazole on Urinary Magnesium Excretion in Children with Peptic Diseases by Fatemeh Famouri, Nirvana Tavahen, Hossein Gholami, Maryam Yazdi, Motahar Heidari-Beni, Mahnaz Momenzadeh

“…Methods: This single-arm clinical trial was conducted from 2020 to 2021. With 44 children diagnosed with acid peptic disease who received omeprazole (1–2 mg/kg/day) for 3 months at the Gastroenterology Clinic of Imam Hossein Hospital, Isfahan, Iran. …”
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Study on the efficacy of fractional CO2 laser treatment for vaginal relaxation syndrome combined with recurrent bacterial vaginitis by Lan Wang, Lulu Chen, Yanhui Li, Xinnan Song, Jiaya Mo, Guoyan Ding, Ying Shen

“…Trial registration: Chinese Clinical Trial Registry, Registration number ChiCTR2400094125.…”
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Short-Term Efficacy of High-Intensity Laser Therapy in Alleviating Pain in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial by Punpetch Siriratna, Chompoonuch Ratanasutiranont, Thongsuk Manissorn, Nonthalee Santiniyom, Waree Chira-Adisai

“…Trial Registration. This clinical trial registration was performed at Clinical.gov (NCT04889885).…”
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