Peripheral nerves adjacent to spinal cord injury could help restore sensory motor regeneration in complete paralysis patients by Mohammad Mousazadeh

“…We developed this novel technique and tested it in four individuals with complete sensory-motor paralysis as part of the ongoing clinical trial. Result: Within 6 months time loop shape frame work stimulation novel technique mediated ASIA score improvement from A score to C score in case 1,2 and after 8 months case three can move his hand and foot, Mr. 4 sensory recovered from umbilical level to beneath of knee and the patient move proximal muscle voluntary (3/5). …”
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Impact of a soft tip nicotine-free harmless cigarette as part of a smoking cessation program with psychological support and varenicline: an integrated workplace smoking cessation i... by Marilena Maglia, Pasquale Caponnetto, Riccardo Polosa, Cristina Russo, Giuseppe Santisi

“…This two-group randomized clinical trial compared the 12-week combined effect of psychological support and varenicline associated with the use or not of a nicotine-free inhaler with a soft mouthpiece (QuitGo™) on the 4 to 24-week cessation rate in enrolled smokers to a smoking cessation program promoted by our research group. …”
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Abdominal plexiform neurofibroma. Case report by José Rolando Rodríguez Núñez, Fernando Karel Fonseca Sosa, Juan Guillermo Bauzá López, Pedro Rafael Casado Mendez

“…Although there is no curative treatment for this disease, surgical resection of the tumor together with the use of drugs that are still in the clinical trial phase have managed to reduce tumor volume and improve quality and life expectancy.…”
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Malignant Bowel Obstruction in Advanced Gynecologic Cancers: An Updated Review from a Multidisciplinary Perspective by Yeh Chen Lee, Nazlin Jivraj, Catherine O’Brien, Tanya Chawla, Eran Shlomovitz, Sarah Buchanan, Jenny Lau, Jennifer Croke, Johane P. Allard, Preeti Dhar, Stephane Laframboise, Sarah E. Ferguson, Neesha Dhani, Marcus Butler, Pamela Ng, Terri Stuart-McEwan, Pamela Savage, Lisa Tinker, Amit M. Oza, Stephanie Lheureux

“…This article focuses on the challenges in developing evidence-based treatment guidelines for MBO and barriers in clinical trial design for MBO and proposes strategies to advance the MBO management. …”
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Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms by Shivan Sivakumar, Ashwin Jainarayanan, Edward Arbe-Barnes, Piyush Kumar Sharma, Maire Ni Leathlobhair, Sakina Amin, David J. Reiss, Lara Heij, Samarth Hegde, Assaf Magen, Felicia Tucci, Bo Sun, Shihong Wu, Nithishwer Mouroug Anand, Hubert Slawinski, Santiago Revale, Isar Nassiri, Jonathon Webber, Gerard D. Hoeltzel, Adam E. Frampton, Georg Wiltberger, Ulf Neumann, Philip Charlton, Laura Spiers, Tim Elliott, Maria Wang, Suzana Couto, Thomas Lila, Pallavur V. Sivakumar, Alexander V. Ratushny, Mark R. Middleton, Dimitra Peppa, Benjamin Fairfax, Miriam Merad, Michael L. Dustin, Enas Abu-Shah, Rachael Bashford-Rogers

“…Analysis of patients from the APACT clinical trial shows that myeloid enrichment had a shorter overall survival compared to those with adaptive cell enrichment. …”
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Predictors for Return to Work in Subjects with Mild Traumatic Brain Injury by Eirik Vikane, Torgeir Hellstrøm, Cecilie Røe, Erik Bautz-Holter, Jörg Aßmus, Jan Sture Skouen

“…The study was conducted as part of a randomised clinical trial. Injury characteristics were obtained from the medical records. …”
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Impact of social support and breastfeeding success on the self-efficacy levels of adolescent mothers during the postpartum period by Veysel Can, Mehmet Bulduk, Emine Kurt Can, Nesrullah Ayşin

“…Conclusions In conclusion, social support networks, including partners, mothers, and mothers-in-law, should be incorporated into breastfeeding training programs to help adolescent mothers leverage these resources effectively. Clinical trial number: Not applicable.…”
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Electroencephalogram biomarkers as predictors of mortality and functional recovery in patients with severe traumatic brain injury: Protocol study by Walter Gomes da Silva Filho, Layza Julhia do Nascimento Moura, Arthur Barcelos Massariol Nascimento, Gabrielle Cristina Tessmann, Fabricia Silva Miranda, Vitória Caroline Reinoso de Almeida, Bárbara Vargens Broedel, Miller Lucas de Faria, Fernando Zanela da Silva Arêas

“…Through continuous monitoring and analysis of abnormal brain activity patterns, the protocol aims to personalize therapeutic interventions and improve patient quality of life. This randomized clinical trial includes 84 adult participants with severe TBI, followed at different stages of recovery, using validated scales for functional and predictive analysis. …”
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A review on current and future advancements for commercialized microalgae species by Jia Fei Wong, Hui Jing Hong, Su Chern Foo, Michelle Khai Khun Yap, Ji Wei Tan

“…Although studies have proved the therapeutic potentials of high-value bioproducts in microalgae, however, there is still room to understand their potential therapeutic properties on humans’ health, discovering novel microalgae-derived bioactive compounds, as well as translating the lab-based evidence to clinical trial studies. This review will focus on accessing the biochemical compositions of commercialised microalgae species from 2007 to 2020, and the activity of their biologically active molecules in eliciting selected therapeutic potentials which are anti-oxidative, anti-inflammatory, anti-microbial and anti-cancer properties. …”
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Our journey with François Gros by Butler-Browne, Gillian, Mouly, Vincent

“…Their group in collaboration with the clinical team of Professor Jean Lacau St-Guily and Professor Sophie Perié completed a successful autologous myoblast transplantation clinical trial for Oculo-pharyngeal muscular dystrophy. …”
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Mathematical modeling of continuous and intermittent androgen suppression for the treatment of advanced prostate cancer by Alacia M. Voth, John G. Alford, Edward W. Swim

“…We will compute and analyze parameter sensitivity analysis for CAS and IAS which may give insight to plan effective data collection in a future clinical trial. Moreover, a periodic model for IAS is used to develop an analytical formulation for relapse times which then provides information about the sensitivity of relapse to the parameters in our models.…”
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The Combined Use of Metformin and Methotrexate in Psoriasis Patients with Metabolic Syndrome by Huynh Thi Xuan Tam, Luong Nguyen Dac Thuy, Ngo Minh Vinh, Tran Ngoc Anh, Bui Thi Van

“…Materials and Methods. A prospective clinical trial was conducted using metformin and MTX to treat psoriasis patients with metabolic syndrome. …”
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Mobile Phone Short Message Service (SMS) for Weight Management in Iranian Overweight and Obese Women: A Pilot Study by Somayeh Faghanipour, Eftekharalsadat Hajikazemi, Soghra Nikpour, Shabnam al-Sadat Shariatpanahi, Agha Fatemeh Hosseini

“…Text messaging seems to be an effective channel of communication for weight management in Iranian overweight and obese women. The clinical trial registration number is IRCT201204029360N1.…”
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Digital humanistic program to manage premature frailty in young breast cancer survivors with gender perspective by Yun Hu, Joshua Wiley, Lulu Jiang, Xiyi Wang, Ran Yi, Jiehui Xu, Yanyan Liu, Aozhou Weng, Futai Zou, Eun-Ok Im

“…This randomized controlled trial, registered at the Chinese Clinical Trial Registry (ChiCTR2200058823), tests the “AI-TA” program’s efficacy on premature frailty and quality of life in YBCSs. …”
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Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Diseas... by Hugh Chan, Helen Paur, Anthony C. Vernon, Virginia Zabarsky, Krishna P. Datla, Martin J. Croucher, David T. Dexter

“…Clinical trials have demonstrated positive proof of efficacy of dual metabotropic glutamate receptor 2/3 (mGluR2/3) agonists in both anxiety and schizophrenia. …”
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Safety of a Bioactive Polyphenol Dietary Supplement in Pediatric Subjects with Acute Diarrhoea by Shafiqul A. Sarker, Shamima Sultana, Mark Pietroni, Arthur Dover

“…The hematological and clinical chemistry profile for children aged 6 months to 5 years with acute diarrhoea was measured in a double blind clinical trial. Subjects were randomized to the study group (N=44) given a bioactive polyphenol dietary supplement in oral rehydration solution (ORS) or to the control group (N=41) given distilled water as a placebo in ORS twice daily for up to 4 days. …”
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Effect of Posture Training with Weighted Kypho-Orthosis (WKO) on Improving Balance in Women with Osteoporosis by Seyed Ahmad Raeissadat, Leyla Sedighipour, Safura Pournajaf, Reza Vahab Kashani, Shahram Sadeghi

“…In this nonrandomized controlled clinical trial, 31 patients with osteoporosis were included. …”
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Whey Protein Lycosome Formulation Improves Vascular Functions and Plasma Lipids with Reduction of Markers of Inflammation and Oxidative Stress in Prehypertension by Ivan M. Petyaev, Pavel Y. Dovgalevsky, Victor A. Klochkov, Natalya E. Chalyk, Nigel Kyle

“…Parameters reflecting cardiovascular health and inflammation were studied in a pilot clinical trial conducted on 40 patients with prehypertension. …”
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Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction by Xiaoling Fu, Yimin Xu, Xinyue Han, Xiangying Lin, Jingnan Wang, Guanhong Li, Xiaochen Fu, Min Zhang

“…Method A randomized controlled clinical trial was conducted, with patients diagnosed with CRA within 6 months as the study subjects. …”
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Metformin increases mammographic breast density: a randomized controlled trial by Sadaf Alipour, Ladan Hosseini, Zohreh Forootan, Hadith Rastad, Leila Bayani, Mahboubeh Abedi, Bita Eslami

“…Conclusions This clinical trial showed that consumption of metformin 500 mg twice daily for 6 months is associated with a higher mammographic breast density as compared to the placebo group. …”
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