Novel oral adjuvant to enhance cytotoxic memory like NK cell responses in HIV vaccine platform by Mario Alles, Manuja Gunasena, Christina Isckarus, Ilmini De Silva, Sarah Board, Will Mulhern, Patrick L. Collins, Thorsten Demberg, Namal P. M. Liyanage

“…Abstract Natural killer (NK) cell-driven effector mechanisms, such as antibody-dependent cell-mediated cytotoxicity, emerged as a secondary correlate of protection in the RV144 HIV vaccine clinical trial, the only vaccine thus far demonstrating some efficacy in human trials. …”
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Analysis of changes in PCSK9 and TNF-α concentrations in response to physical exercises using virtual reality in patients in the fifth stage of chronic kidney disease undergoing he... by Agnieszka Turoń-Skrzypińska, Alicja Mińko, Aleksandra Rył, Aneta Cymbaluk-Płoska, Maciej Domański, Kazimierz Ciechanowski, Iwona Rotter

“…Conclusion Regular physical activity using innovative physiotherapy methods, such as virtual reality, contributes to the improvement of inflammatory parameters and may improve lipid homeostasis. Clinical trial number not applicable.…”
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Does the “state of disaster” response have a downside? Hospital incident command group leaders’ experiences of a terrorist-induced major incident: a qualitative study by Jason P. Murphy, Anna Hörberg, Monica Rådestad RN, Lisa Kurland, Maria Jirwe

“…In addition, the results suggest that an exaggerated response may have led to unanticipated adverse events. Clinical trial number Not applicable.…”
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Phenolic Compounds and Anthocyanins in Legumes and Their Impact on Inflammation, Oxidative Stress, and Metabolism: Comprehensive Review by Rocio Guadalupe Hernández-Ruiz, Xochitl Citalli Olivares-Ochoa, Yahatziri Salinas-Varela, David Guajardo-Espinoza, Luis Gustavo Roldán-Flores, Edgar Alfonso Rivera-Leon, Andres López-Quintero

“…In vivo, in vitro, and clinical trial studies demonstrate that these compounds can modulate key cellular signaling pathways involved in inflammation and metabolism, improving insulin sensitivity and regulating lipid and glucose metabolism. …”
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Comparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases by Celal Saritoy, Erol Karaaslan, Ahmet Selim Ozkan, Mehmet Tan, Ilham Gulcek

“…The study was planned as a prospective, double-blind, and randomized clinical trial. A total of 64 patients aged between 18 and 65 were included in the study and the patients were randomized into 2 groups: Group N (Nicardipine=32) and Group R (Remifentanil=32). …”
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Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial by Jing Li, Fei Chen, Wei Xiao, Feng Li, Lan Chen, Ting He, Yanxiong Mao, Aiping Zou, Bo Fan, Weihao Ni, Huimin You, Wenjiang Fu

“…This protocol describes a head-to-head clinical trial designed to compare the efficacy of two dosing regimens of azithromycin in Chinese NCFB population.Methods and analysis This prospective, open-label and randomised controlled trial will be conducted in the First People’s Hospital of Jiashan, China. …”
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Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges by Inga Brockmann, Juliet Ehrenpfordt, Tabea Sturmheit, Matthias Brandenburger, Charli Kruse, Marietta Zille, Dorothee Rose, Johannes Boltze

“…We further provide an overview of clinical trial activities in the field and discuss relevant translational and clinical challenges associated with the use of these products.…”
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Differences between SSRI and SNRI in depression treatment by Mateusz Grego, Katarzyna Grego, Łukasz Stojak, Dariusz Popiela, Karina Urbańska, Filip Kwiatkowski, Mateusz Baczewski, Witold Czyż

“…Conclusion The review of the literature and clinical trial results shows that no single universal group of medications can be identified for depression therapy. …”
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Randomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity by Hiroko Ochiai, Shigeru Inoue, Gaku Masuda, Shiho Amagasa, Tomohiko Sugishita, Toshiya Ochiai, Naoko Yanagisawa, Yoshio Nakata, Michiko Imai

“…In conclusion, mindful forest walking has the potential to enhance immunity and promote health. Clinical trial registration: University Hospital Medical Information Network. …”
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A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in He... by Lee HW, Kang WY, Park JS, Lee JH, Park JJ, Gwon MR, Yoon YR, Seong SJ

“…YYD601 20 mg was safe and well tolerated following single and multiple oral administrations, supporting its use as an effective alternative to conventional esomeprazole therapy.Clinical Trial Registry: http://clinicaltrials.gov, NCT03985319 (Date of registration: May 29, 2019; Study period: between July 2019 and March 2020).Keywords: esomeprazole, dual delayed-release formulation, pharmacokinetics, pharmacodynamics…”
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Dosimetric Comparison of Noncoplanar VMAT Without Rotating the Patient Couch Versus Conventional Coplanar/Noncoplanar VMAT for Head and Neck Cancer: First Report of Dynamic Swing A... by Kouta Hirotaki, MS, Kento Tomizawa, MD, PhD, Satoe Kitou, BS, Shunta Jinno, MS, Shunsuke Moriya, PhD, Takeshi Fujisawa, MD, Sadamoto Zenda, MD, PhD, Takeji Sakae, PhD, Masashi Ito, BS

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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…Methods we performed a prospective multicenter randomized clinical trial (STOP) and followed up patients over 5 years (May 2014 – Nov. 2020) at 4 centers and around Cologne, Germany. …”
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Pengaruh Terapi Oksigen Menggunakan Non-Rebreathing Mask Terhadap Tekanan Parsial CO2 Darah pada Pasien Cedera Kepala Sedang by Hendrizal ., Syaiful Saanin, Hafni Bachtiar

“…Metode: Penelitian ini merupakan penelitian Clinical Trial dengan rancangan penelitian one shoot pretest and postest pada pasien cedera kepala sedang dengan GCS 9-13 yang dilakukan terapi konservatif di RS Dr. …”
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Effects of Dexmedetomidine as an Adjuvant in Preoperative Ultrasound-Guided Internal Branch of Superior Laryngeal Nerve Block on Postoperative Sore Throat and Hemodynamics in Patie... by Chen Z, Zhang L, Lu G, Zhang Y, Zhao D, Zhao S, Zhang H, Jin Y, Zhao X, Jin Y

“…No additional hemodynamic benefits were observed.Clinical Trial Registration: Chinese Clinical Trial Registry (ChiCTR2200061001).Keywords: dexmedetomidine, superior laryngeal nerve, sore throat, cough, hemodynamics…”
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Grepafloxacin Clinical Program for Lower Respiratory Tract Infections by Arne C Rodloff

“…The present paper evaluates the clinical trial program in lower respiratory tract infections treated with a new fluoroquinolone antibiotic, grepafloxacin. …”
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Diabetes Technology: Markers, Monitoring, Assessment, and Control of Blood Glucose Fluctuations in Diabetes by Boris P. Kovatchev

“…Following a number of in-clinic trials, the quest for a wearable ambulatory artificial pancreas is under way, with a first prototype tested in outpatient setting during the past year. …”
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The Effects of Morus alba and Acacia catechu on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee by Douglas S. Kalman, Susan J. Hewlings

“…This study is registered with Clinical Trial ID ISRCTN15418623.…”
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Comparison of gingivectomy procedures for patient satisfaction: Conventional and diode laser surgery by Elif Öncü

“…Background: To compare the use of the 940 nm diode laser with conventional surgery in the management of soft tissue in gingivectomy procedures in terms of patient satisfaction.Methods: This controlled clinical trial was conducted on 20 healthy patients who needing esthetic-only gingivectomy in the anterior maxilla. …”
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Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy by James C. L. Chow

“…By facilitating personalized nanomedicine and streamlining regulatory and clinical trial processes, MC simulations offer a pathway toward more effective, tailored, and accessible cancer treatments. …”
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Current trends in peanut allergy immunotherapy: a review by Klementyna Łyżwa, Anna Krupa-Łaska, Joanna Zielińska, Marek Kulus, Katarzyna Grzela

“…In addition, the translation of clinical trial results into real-world settings remains a critical issue, as shown by low participation rates in immunotherapy programs. …”
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